• Journal of the Korea Convergence Society
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• v.12 no.1
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• pp.243-250
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• 2021

In the medical field, applications of plasma are applied sterilize instruments mainly but with the advent of bio-plasma technology, the scope of application is expanding. Recently, In addition, high-density miniaturization with handheld is required for sophisticated procedures when irradiated directly or treated with non-standard conditions. Rosen-type PZT is a device with a structure that generates high voltage plasma by achieving voltage transformation through electro-mechanical coupling using piezoelectric effect.and is used in portable plasma generating devices as an advantage to increase energy density relatively. In this paper, Rosen-type PZT was modeled using equivalent circuits and was carried out and a plasma generating device for medical application was designed and prototype tested. Prototype plasma generating device generates an output voltage of 5.8 kV with 12V input power and is designed to operate at high voltage by applying the half-bridge topology power converter. The results of the study confirmed the availability of various medical devices, such as plasma jets or direct exposure equipment.

• The Journal of the Convergence on Culture Technology
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• v.7 no.1
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• pp.1-10
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• 2021

This study was intended to prepare a basis to apply one time laughter therapy in clinical circumstances as an intervention for reducing job stress and improve job involvement of geriatric hospital workers by identifying the effect of one time laughter therapy on their physiological stress responses, job stress, and job involvement. This study was a Non-Equivalent control group pre-post design to validate the effect of one time laughter therapy. The participants of this study included 80 staffs of 2 geriatric hospitals located in I city, including 40 persons in each experimental and control group. Consent was obtained from the participants, after explaining sufficiently study purpose, blood pressure and pulse rate measurement, serum cortisol level measurement, and a questionnaire on job stress and job involvement and data collection was performed 2 times each, before and after the experimental procedure. For the collected data, frequency, percentage, average and standard deviation, χ2 test, Fisher's exact test and t-test were conducted using SPSS Win 19.0. The results of this study were as follows. The systolic blood pressure and the serum cortisol level were reduced significantly. It was found that although there was no significant difference between the experimental group and the control group in job stress and job involvement. Therefore, it was identified that the one time laughter therapy was an effective nursing intervention to reduce physiological stress response of geriatric hospital workers.

• Korean Journal of Food Science and Technology
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• v.53 no.1
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• pp.19-28
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• 2021

Vitamin E and K are essential micronutrients required by our body in small amounts for proper metabolic functions; however, the content of vitamin E and K commonly consumed in foods has not been comprehensively defined. In this study, the contents of vitamins E and K in sea algae and vegetables were analyzed and the analytical methods were validated. The α-tocopherol equivalent (α-TE) and vitamin K1 content in sea algae ranged from 0.15 to 1.14 mg/100 g and from 11.91 to 1,629.5 ㎍/100 g, respectively. In addition, α-TE and vitamin K1 of vegetables were detected in the range of 0.02-2.48 mg/100 g and 16.15-979.60 ㎍/100 g, respectively. In particular, β- and γ-tocopherol and α- and β-tocotrienol were detected in several vegetables. The analytical methods were accurate and reproducible. These results provide reliable data on the vitamin E and K contents of foods consumed in Korea for the development of National Standard Food Composition Database.

• Structural Engineering and Mechanics
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• v.76 no.6
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• pp.687-708
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• 2020

Openings in steel plate shear walls (SPSWs) are usually used for decorative designs, crossing locations of multiple utilities and/or structural objectives. However, earlier studies showed that generating an opening in an SPSW has a negative effect on the cyclic performance of the SPSW. Therefore, this study proposes tripling or doubling the steel-sheet-plate (SSP) layer and stiffening the opening of the SPSW to provide a solution to undesirable opening effects, improve the SPSW performance and provide the infill option of potential strengthening measures after the construction stage. The study aims to investigate the impact of SSP doubling with a stiffened opening on the cyclic behaviour, expand the essential data required by structural designers and quantify the SPSW performance factors. Validated numerical models were adopted to identify the influence of the chosen parameters on the cyclic capacity, energy dissipation, ductility, seismic performance factors (SPF) and stiffness of the suggested method. A finite Element (FE) analysis was performed via Abaqus/CAE software on half-scale single-story models of SPSWs exposed to cyclic loading. The key parameters included the number of SSP layers, the opening size ratios corresponding to the net width of the SSP, and the opening shape. The findings showed that the proposed assembly method found a negligible influence in the shear capacity with opening sizes of 10, 15, 20%. However, a deterioration in the wall strength was observed for openings with sizes of 25% and 30%. The circular opening is preferable compared with the square opening. Moreover, for all the models, the average value of the obtained ductility did not show substantial changes and the ultimate shear resistance was achieved after reaching a drift ratio of 4.36%. Additionally, the equivalent sectional area of the SSP in the twin and triple configuration of the SPSWs demonstrated approximately similar results. Compared with the single SSP layer, the proposed configuration of the twin SSP layer with a stiffened opening suggest to more sufficiency create SSP openings in the SPSW compared to that of other configurations. Finally, a tabular SPF quantification is exhibited for SPSWs with openings.

• Journal of the Korean GEO-environmental Society
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• v.12 no.1
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• pp.61-70
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• 2011

The impact protection system consists of an arrangement of circular sheet pile cofferdams-denoted dolphin structuredeeply embedded in the seabed, filled with crushed rock and closed at the top with a robust concrete cap. Centrifuge model tests were performed to investigation the behaviors of dolphins in this study. Total 7 quasi-model tests and 11 dynamic model tests were performed. The main experimental results can be summarized as follows. Firstly, The experimental force-displacement results for quasi-static tests show a limited influence on the initial stiffness of the structure from the change in fill density and the related change in the stiffness of the fill. And by comparing the dissipation at the same dolphin displacement it was found that the denser fill increase the dissipation by 16% for the 20m dolphin and by 23% for the 30m dolphin. The larger sensitivity for the large dolphin is explained by a larger contribution to the dissipation from strain in the fill. In low level impacts the dynamic force-response is up to 26~58% larger than the quasi-static and the dissipation response is showed larger in small displacement. Hence, it is concluded conservative to use the quasi-static response characteristics in the approximation of the response, and it is further concluded that the dolphin resistance to low level impacts is demonstrated to be equivalent and even superior to the high level impacts.

• Translational and Clinical Pharmacology
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• v.25 no.3
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• pp.153-156
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• 2017

UI14SDF100CW is a chewable tablet of sildenafil citrate, which was developed to improve compliance through convenience of administration. The purpose of this study was to compare the pharmacokinetic (PK) properties of sildenafil citrate chewable tablets (UI14SDF100CW) and conventional sildenafil citrate film-coated tablets ($Viagra^{(R)}$, Pfizer). A randomized, open-label, single dose, two-treatment, two-period, two-way crossover study was conducted in 60 healthy male volunteers. In each period, the subjects received a single oral dose of UI14SDF100CW or $Viagra^{(R)}$ (both tablets contain 140.45 mg of sildenafil citrate, which is equivalent to 100 mg of sildenafil). Serial blood samples were collected up to 24 h post-dose for PK analysis. The plasma concentration of sildenafil was determined using a validated HPLC-MS/MS assay. PK parameters of sildenafil were calculated using non-compartmental methods. The plasma concentration-time profiles of sildenafil in both formulations were similar. For UI14SDF100CW, the $C_{max}$ and $AUC_{last}$ of sildenafil were $1068.69{\pm}458.25$ (mean${\pm}$standard deviation) mg/L and $3580.59{\pm}1680.29h{\cdot}mg/L$, and the corresponding values for $Viagra^{(R)}$ were $1146.84{\pm}501.70mg/L$ and $3406.35{\pm}1452.31h{\cdot}mg/L$, respectively. The geometric mean ratios (90% confidence intervals) of UI14SDF100CW to $Viagra^{(R)}$ for $C_{max}$ and $AUC_{last}$ were 0.933 (0.853-1.021) and 1.034 (0.969-1.108), respectively, which met the bioequivalence criteria of Korean regulatory agency. In conclusion, UI14SDF100CW and $Viagra^{(R)}$ showed similar PK properties. Therefore, UI14SDF100CW can be an alternative to sildenafil for the treatment of erectile dysfunction, providing better compliance.

• Journal of the Korea Institute of Information Security & Cryptology
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• v.18 no.6A
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• pp.139-149
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• 2008

The amount of personal information collected by organizations and government agencies is continuously increasing. When a data collector publishes personal information for research and other purposes, individuals' sensitive information should not be revealed. On the other hand, published data is also required to provide accurate statistical information for analysis. k-Anonymity and ${\iota}$-diversity models are popular approaches for privacy preserving data publication. However, they are limited to static data release. After a dataset is updated with insertions and deletions, a data collector cannot safely release up-to-date information. Recently, the m-invariance model has been proposed to support re-publication of dynamic datasets. However, the m-invariant generalization can cause high information loss. In addition, if the adversary already obtained sensitive values of some individuals before accessing released information, the m-invariance leads to severe privacy disclosure. In this paper, we propose a novel technique for safely releasing dynamic datasets. The proposed technique offers a simple and effective method for handling inserted and deleted records without generalization. It also gives equivalent degree of privacy preservation to the m-invariance model.

• Journal of the Korea Institute of Information Security & Cryptology
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• v.22 no.2
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• pp.201-211
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• 2012

This paper addresses a Full Disk Encryption hardware processor for SATA HDD in a single FPGA design, and shows its experimental result using an FPGA board. The proposed processor mainly consists of two blocks: the first block processes XTS-AES block cipher which is the IEEE P1619 standard of storage media encryption and the second block executes the interface between SATA Host (PC) and Device (HDD). To minimize the performance degradation, we designed the XTS-AES block with the 4-stage pipelined structure which can process a 128-bit block per 4 clock cycles and has 4.8Gbps (max) performance. Also, we implemented the proposed design with Xilinx ML507 FPGA board and our experiment showed 140MB/sec read/write speed in Windows XP 32-bit and a SATA II HDD. This performance is almost equivalent with the speed of the direct SATA connection without FDE devices, hence our proposed processor is very suitable for SATA HDD Full Disk Encryption environments.

• Korean Journal of Construction Engineering and Management
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• v.22 no.4
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• pp.20-28
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• 2021

The Domestic Construction Industry is in the process of changing from a one-sided production method centered on the contractor to a production method in which the order and the contractor can collaborate. Depending on the delivery method, the bid/success method, the contract method, and the degree of business involvement of the order may also vary. In this thesis, in order to introduce 'Construction Management at Risk' suitable for the domestic environment, domestic and foreign institutional analysis, bid process analysis, contract fulfillment and management analysis, post management analysis, and related laws and regulations for legalization In order to suggest a plan for the efficient operation of the system, a system and case analysis of domestic and international construction responsibility type construction project management was conducted. 'Construction Responsible Construction Project Management' defined in the Framework Act on the Construction Industry is divided into the main contract transfer contract, which is a service contract performing pre-con work, and the main contract, which is construction project management and construction contract. Therefore 'Construction Management at Risk' should be regarded as one of the ordering methods rather than a successful bid system, as in the case of overseas, and legalization as a bidding system equivalent to design/construction batch bid and technology proposal is necessary for introduction. In order to introduce 'Construction Management at Risk' suitable for the domestic environment, domestic and foreign institutional analysis, bidding process analysis, contract fulfillment and management analysis, and follow-up management analysis are conducted. A method for efficient operation was suggested so that it can be applied in the domestic market while maintaining the original merits of this system.

• Animal Bioscience
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• v.34 no.7
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• pp.1169-1180
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• 2021

Objective: This research aimed to study the effects of Artemisia argyi flavonoids (AAF) supplemented in diets on the growth performance and immune function of broiler chickens challenged with lipopolysaccharide (LPS). Methods: A total of one hundred and ninety-two 1-d-old broiler chicks were assigned into 4 treatment groups, which were, respectively, fed a basal diet (control), fed a diet with 750 mg/kg AAF, fed a basal diet, and challenged with LPS, fed a diet with 750 mg/kg AAF, and challenged with LPS. Each treatment had six pens with 8 chicks per pen. On days 14, 16, 18, 20 (stress phase I) and 28, 30, 32, 34 (stress phase II), broilers were injected with LPS (500 ㎍/kg body weight) or an equivalent amount of saline. Results: The results demonstrated that dietary AAF significantly improved the body weight (d 21) and alleviated the decrease of average daily gain in broilers challenged with LPS on d 21 and d 35 (p<0.05). Dietary AAF increased bursa fabricius index, and dramatically attenuated the elevation of spleen index caused by LPS on d 35 (p<0.05). Furthermore, serum interleukin-6 (IL-6) concentration decreased with AAF supplementation on d 21 (p<0.05). Diet treatment and LPS challenge exhibited a significant interaction for the concentration of IL-1β (d 21) and IL-6 (d 35) in serum (p<0.05). Additionally, AAF supplementation mitigated the increase of IL-1β, IL-6 in liver and spleen induced by LPS on d 21 and 35 (p<0.05). This study also showed that AAF supplementation significantly reduced the expression of IL-1β (d 21) and nuclear transcription factor kappa-B p65 (d 21 and 35) in liver (p<0.05), and dietary AAF and LPS treatment exhibited significant interaction for the gene expression of IL-6 (d 21), toll like receptor 4 (d 35) and myeloid differentiation factor 88 (d 35) in spleen (p<0.05). Conclusion: In conclusion, AAF could be used as a potential natural immunomodulator to improve growth performance and alleviate immune stress in broilers challenged with LPS.