• Title/Summary/Keyword: eosinophilic granuloma

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A Case Report of Eosinophilic Granuloma in the Frontal Bone (전두골에 발생한 호산구성육아종의 치험례)

  • Shim, Seung-Hyun;Chung, Chul-Hoon;Chang, Yong-Joon
    • Korean Journal of Head & Neck Oncology
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    • v.26 no.2
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    • pp.243-246
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    • 2010
  • Purpose : Eosinophilic granuloma is a rare benign tumor that is characterized histologically by the presence of destructive granulomas containing numerous Langerhans, cells. The most common presentation of eosinophilic granuloma is a painful, immobile scalp mass in the frontal and parietal bones occurring predominantly in children and adolescents or young adults. We report a representative case of eosinophilic granuloma. Methods : A 16-year-old woman complained of an enlarging fixed scalp mass without pain and tenderness which measured $3{\times}4.5cm$ at the frontal area, which had been found incidentally 2 months before. Plain skull x-ray showed a punched-out bone lesion. Computed tomography and magnetic resonance imaging showed a non-enhancing osteolytic lesion. The tumor and surrounding bony edges were completely removed via a bicoronal approach. The bony defect was reconstructed with bone cement. Results : The tumor was involved frontal bone and dura mater. We confirmed the tumor by the documentation of Birbeck's granules by electron microscopy. There is no evidence of local recurrence during postoperative 1.5 years. Conclusion : The present case shows the characteristic feature of frontal bone involvment of the eosinophilic granuloma. The prognosis of eosinophilic granuloma depend on age at diagnosis and number of bones involved. We consider that best choice of treatment for eosinophilic granuloma is surgical excision.

Eosinophilic granuloma in the anterior mandible mimicking radicular cyst

  • Lee, Byung-Do;Lee, Wan;Lee, Jun;Son, Hyun-Jin
    • Imaging Science in Dentistry
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    • v.43 no.2
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    • pp.117-122
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    • 2013
  • Eosinophilic granuloma is a common expression of Langerhans cell histiocytosis and corresponds with typical bone lesions. The radiographic appearance of eosinophilic granuloma in the jaw is variable and not specific. It may resemble periodontitis, radicular cyst, or malignancies. The purpose of this report is to describe the characteristic radiographic features of eosinophilic granuloma of a 39-year-old male. The lesion in the anterior mandible was first diagnosed as radicular cyst because the radiographic findings were ovoid radiolucent lesion with well-defined border. However, careful interpretation revealed a non-corticated border and floating tooth appearance that were the characteristic radiographic features for the differential diagnosis. Early clinical signs of eosinophilic granuloma can occur in the jaw and a bony destructive lesion might be mistaken for periodontitis or an odontogenic cystic lesion; therefore, careful interpretation of radiographs should be emphasized.

A Case of Pulmonary Eosinophilic Granuloma Involving Mediastinal Lymph Node (종격동 임파절 침범을 동반한 폐 호산구성 육아종 1예)

  • Kwak, Seung-Min;Kim, Se-Kyu;Shin, Dong-Hwan;Chung, Kyung-Young;Jang, Joong-Hyun;Lee, Hong-Lyeol;Kim, Sung-Kyu;Lee, Won-Young
    • Tuberculosis and Respiratory Diseases
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    • v.40 no.4
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    • pp.424-430
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    • 1993
  • Pulmonary eosinophilic granuloma or histiocytosis X is a chronic interstitial lung disease characterized by proliferations of Langerhans cells and, therefore, not truly histiocytosis. Both histiocytes and Langerhans cells are believed to be related to the mononuclear phagocyte system. In Eosinophilic granuloma, extra-pulmonary such as mediastinal or hilar lymph nodes involvement is very rare in adult. We report a case of young man with eosinophilic granuloma involving lung and anterior mediastinal lymph node simultaneously which is confirmed by open thoracotomy.

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Eosinophilic granuloma at the sternum associated with diabetes insipidus -One case report- (뇨붕증을 동반한 흉골의 소산구성 육아종 치험 1례)

  • Park, Hui-Cheol;Sin, Ho-Seung;Hong, Gi-U
    • Journal of Chest Surgery
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    • v.19 no.2
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    • pp.325-330
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    • 1986
  • Eosinophilic granuloma is one of the histiocytosis X. It may occur in any bone and tissues, but the one originated from the sternum was rarely reported. Recently, we experienced an eosinophilic granuloma at the manubrium sterni, associated with diabetes insipidus, which was surgically resected. Although intranasal spray of DDAVP has been used for the control of diabetes insipidus, the bony lesion was remitted. With the brief review of the literatures, we report the case.

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Eosinophilic granulomas in two dogs

  • Kim, Jae-Hoon;Jung, Ji-Youl;Kang, Sang-Chul;Lee, Young-Rak;Lee, Jin-Yong;Hwang, Eui-Kyung;Woo, Gye-Hyeong;Kim, Jae-Hoon
    • Korean Journal of Veterinary Research
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    • v.51 no.1
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    • pp.69-72
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    • 2011
  • Eosinophilic granuloma is a common hypersensitive inflammatory skin disease in cats, and rare in dogs and horses. The skin biopsies of 5 years old female Cocker spaniel and 2 years old female mixed dog had the clinical signs of skin nodules with alopecia were submitted for diagnosis. Solitary skin nodules and papillary nodules were presented on the left external ear and back of Cocker spaniel and on the external ear of mixed dog, respectively. Histopathologically, epidermis of skin showed mild to severe hyperplasia with multifocal ulceration. Small to large irregular, brightly eosinophilic foci with degenerating eosinophils and homogeneous degenerated collagens were existed in the dermis of both ear and back skin. Typical 'flame figures', a mixture of degenerated collagen and degranulated eosinophils, were observed in both cases. Based on the histopathologic findings and special staining characters, 2 cases were diagnosed as canine eosinophilic granuloma. This is the first report for the eosinophilic granuloma of dogs in Korea.

Eosinophilic Granuloma 일예보고

  • Kim, Dong-Sun;Oe, Sam-Myeong
    • The Journal of the Korean dental association
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    • v.5 no.1
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    • pp.71-74
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    • 1964
  • The authors have observed a case of eosinophilic granuloma which occurred in 10 years old girl 1.The lesion which occurred swelling and facial disfigurement , was located in the right side of ramus mandible, but toothache and loosening of tooth was absent. 2. Roentgenograph showed bean-sized monocystic radiolucent shadow in mandible border.3. Microscopically,few hemorrhagic araas were existed, and numerous eosinophilic leukocytes eosinophilic myelocyteswith inflammatory cells were infiltrated.

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Eosinophilic granuloma of the mandibular condyle (하악과두에 발생한 호산구육아종)

  • Choi, Mun-Kyung;Huh, Kyung-Hoe;Yi, Won-Jin;Oh, Sung-Wook;Lee, Sam-Sun
    • Imaging Science in Dentistry
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    • v.38 no.1
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    • pp.63-67
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    • 2008
  • The present study reports a case of eosinophilic granuloma of the mandibular condyle. Eosinophilic granulomas on the mandibular condyle are very rare, but there are several common clinical and radiographic presentations. The clinical presentations involve swelling on preauricular area, limitation of opening, TMJ pain, etc. The radiographic presentations involve radiolucent lytic condylar lesion with or without pathologic fracture. Sometimes new bone formations are observed. The purpose of the article is to add new cases to the literatures.

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Eosinophilic Granuloma Presenting as an Epidural Hematoma and Cyst

  • Lee, Young-Suk;Kwon, Jeong-Taik;Park, Yong-Sook
    • Journal of Korean Neurosurgical Society
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    • v.43 no.6
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    • pp.304-306
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    • 2008
  • Langerhans' cell histiocytosis (LCH) is a rare immunologic disorder characterized by histiocyte proliferation in multiple organ systems. Eosinophilic granuloma, a benign bone lesion, represents a focal form of LCH. We experienced a case of Langerhans' cell histiocytosis in a patient who presented with intracranial epidural hematoma and cyst on the midline of the frontal skull. A 10-year-old boy presented with a rapidly growing large scalp mass on the midline frontal area after mild head trauma. The scalp mass was painless and immobile. Plain skull x-ray showed a punched-out bone lesion. Computed tomography and magnetic resonance imaging showed a non-enhancing osteolytic lesion presenting with an epidural hematoma and cyst on the midline of the frontal skull. The lesion of the skull was completely resected and the patient's recovery was uneventful. The acute presentation of a solitary eosinophilic granuloma of skull with an epidural hematoma has been described in only five cases in the literature and we report the first case of LCH presenting as an intracranial epidural hematoma on frontal area.

A Case of Pulmonary Histiocytosis-X Associated with Bilateral, Recurrent, and Spontaneous Pneumothorax (양측성, 재발성 자연기흉을 동반한 폐 조직구증 1예)

  • Hong, Sa-Joon;Ahn, Kang-Hyun;Lee, Won-Yeon;Kong, Sue-Jung;Yong, Suk-Joong;Shin, Kye-Chul
    • Tuberculosis and Respiratory Diseases
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    • v.41 no.2
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    • pp.152-157
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    • 1994
  • Histiocytosis-X is a tenn used to define three diseases with similar morphologic characteristics : Letterer-Siwe diseae, Hand-Schuller-Christian disease and Eosinophilic granuloma. In general, they differ in terms of their age of onset, severity of clinical course and site of involvement. Eosinophilic granuloma typically is seen in young adults. Eosinophilic granuloma is diagnosed in the presense of diffuse pulmonary infiltrate, bony involvement. However, the pulmonary radiologic findings of eosinophilic granuloma are variable accordinary to stage of disease. therefore pathologic diagnosis of involving site is essential for confirmative diagnosis of eosinophilic grananuloma. Pathologically. the three disease are characterized by granulomatous infiltration of alveolar septa and bronchial walls and often involvement of bone. The hallmark of this disease is proliferation of the Langerhans' cell. The identifying feature is the X-body or Birbeck granule that is present in Langerhans' cells and histiocytic cells found in the lung of EG patient. We report a case of bilatera1, recurrent and spontaneous pneumothoraces in a 21 year old man with pulmonary histiocytosis-X, which is confirmed by eosinophilc granuloma in bone marrow biopsy and ultrastructural examination in cells obtained from BAL.

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Surgical Treatment of Eosinophilic Granuloma in Cervical Spine - 3 Cases Report - (경추에서 발생한 호산구 육아종의 수술적 치료 - 3예 보고 -)

  • Chung, Jae-Yoon;Lee, Jae-Joon;Kim, Jong-Seon;Jung, Sung-Taek
    • The Journal of the Korean bone and joint tumor society
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    • v.12 no.2
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    • pp.171-175
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    • 2006
  • The involvement in the spine of eosinophilic granuloma is not common. Especially, involvement of cervical spine and posterior neural arch is quite rare. In addition, radiographic findings including magnetic resonance images of eosinophilic granuloma are manifested as vertebral body collapse, loss of pedicle and paravertebral soft mass formation; it must be differentiated with other conditions, such as malignant bone tumor, metastatic cancer or tuberculous spondylitis. We experienced three cases of eosinophilic granuloma involving posterior neural arch of C4, C7, and body of C4 respectively, which were performed surgical treatment and achieved complete healing. We report these cases with review of literatures.

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