• 한국식생활문화학회지
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• 제17권2호
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• pp.153-164
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• 2002

This study examined the consumers' awareness and information need toward the irradiated foods and environmental hormones. The data were collected from 350 adults living in Daegu and Busan by the self-administered questionnaire. Frequencies and chi-square tests were conducted by SPSS. The results of the survey were as follows: (1) consumers' awareness regarding the irradiated foods and environmental hormones were low, while consumers' concerns for them were high, (2) the orders of the information needs for the irradiated foods are safety of irradiated foods, dose permitted for food irradiation, benefits of irradiated foods, kinds of permitted irradiated foods, and legislations of food irradiation, and (3) the orders of the information needs for the environmental hormones are harmfulness of environmental hormones, standards for contamination by environmental hormones, materials releasing environmental hormones, methods to prevent environmental hormones, and kinds of environmental hormones.

• 한국직업건강간호학회지
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• 제28권4호
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• pp.285-292
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• 2019

Purpose: This study aimed to examine the factors associated with behavior that reduces exposure to environmental hormones among nursing students. Methods: Data were collected from 160 nursing students in D and B cities, using self-report questionnaires. Data were analyzed using SPSS 22.0, and the analyses included descriptive statistics, t-test, ANOVA, Pearson's correlation coefficient test, and stepwise multiple regression. Results: Behavior that reduces exposure to environmental hormones differed significantly in terms of the participants' knowledge about environmental hormones. Behavior that reduces exposure to environmental hormones was negatively correlated with knowledge of environmental hormones, attitude towards pro-environmental behavior, and environmental self-efficacy; these factors were significant predictors of behavior that reduces exposure to environmental hormones, and accounted for 27.0% of the variance. Conclusion: Environmental self-efficacy was identified as the most significant factor affecting behavior that reduces exposure to environmental hormones in nursing students. Therefore, it is necessary to develop programs to improve pro-environmental behavior and environmental self-efficacy in nursing students.

• Bulletin of the Korean Chemical Society
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• 제32권3호
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• pp.809-814
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• 2011

A method based on the TMS derivatives and acidic hydrolysis was developed for the simultaneous determination of free and conjugated steroidal hormones in surface water. A silylation of five natural and two synthetic steroidal hormones was achieved with N-methyl-N-(trimethylsilyl) trifluoroacetamide/$NH_4I$ (1000:3) under catalysis of dithioerythritol for 60 min at $80^{\circ}C$. TMS derivatives of the steroid hormones containing multifunctional groups offer a single derivative product under this condition. The accuracy of the analytes was in the range of 87 to 110% at a concentration of 20 and 50 ng/L with relative standard deviations of less than 10%. The method detection limit was in the range of 0.01 to 0.02 ng/L for surface water. Natural steroidal hormones were detected in a concentration range of 0 to 1.03 ng/L in free form and 0 to 14.6 ng/L in conjugated form, respectively. We found that most of the natural hormonal steroids exist in conjugate forms (43 to 100%) in river water.

• Journal of Korean Dental Science
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• 제10권1호
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• pp.1-9
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• 2017

There is increasing evidence that the environmental hormones may adversely affect the human body. The human reproductive system misrecognizes some of these endocrine disruptors with consequences to reproductive cell differentiation. Therefore, studies on the safety of these substances have been widely carried out to develop the science to create effective legislation to limit or prevent their use or require the development of inert, alternative substances. A few studies have reported that the oral cavity is the pathway for absorption of these substances released from plastic products or environmental hormone substances. This review suggests that the oral environment is vulnerable to exposure to environmental hormones and introduces supporting literature.

• 한국식품영양과학회지
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• 제36권7호
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• pp.825-831
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• 2007

당귀로부터 분리한 decursin을 환경호르몬에 의해 증식을 유도한 인체 유방암세포(MCF-7)에 처리한 후 그 억제효과를 조사하였다. 인체 유방암세포주인 MCF-7은 20, 40, 60, 80 및 100 ${\mu}g/mL$ 농도로 decursin의 처리 시 20 ${\mu}g/mL$ 이상에서 농도 의존적으로 그 증식이 억제되었다. 호르몬이 제거된 배지로 배양한 세포에 0, 0.01, 0.1 및 1 ${\mu}M$의 농도로 환경 호르몬 $17{\beta}$-estradiol과 bisphenol을 처리한 결과 호르몬이 제거된 배지로 배양한 세포에 비해 세포의 증식을 유도하였으며, Yamada(21)와 본 실험 결과가 유사한 세포성장을 보여 암세포의 성장억제 효과를 측정하기 위한 환경호르몬의 농도를 0.1 ${\mu}M$로 하였다. 환경호르몬에 의해 증식이 유도된 MCF-7 세포에 당귀 메탄올추출물 및 decursin을 1, 3, 10 및 30 ${\mu}g/mL$ 농도로 처리한 결과 농도에 비례하여 세포의 증식을 억제하였으며, 10 ${\mu}g/mL$의 농도 이상에서는 대조구의 증식보다도 낮은 생존율을 나타내어 강한 세포독성을 나타내었다. 또한 hoechst 염색을 통하여 세포 핵의 변화를 알아본 결과 decursin 처리군에서 핵의 응축과 apoptic body가 관찰되어 decursin은 apoptosis를 유도함으로써 환경호르몬이 처리된 MCF-7 세포의 증식을 억제하는 것으로 판단된다. 이들 결과는 decursin이 환경호르몬에 의해 증식이 유도되는 MCF-7 세포의 성장을 apoptosis에 의해 억제한다는 것을 나타낸다.

• Molecular & Cellular Toxicology
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• 제4권3호
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• pp.230-234
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• 2008

Epidemiological studies demonstrate an adverse effect of several environmental and occupational exposures on male sex hormone. Bisphenol A (BPA) is a weak estrogen and a widely used industrial chemical. Epoxy resin painters may be continuously exposed to BPA at high concentrations. The effect of occupational exposure of BPA on male reproduction was examined by measuring the urinary BPA, testosterone and gonadotropic hormones of epoxy resin painters in the shipyard. The painters had significantly higher concentrations of urinary BPA (2.61${\pm}$1.08 ${\mu}g$/g creatinine) than controls (1.38${\pm}$0.5 9 ${\mu}g$/g creatinine). In serum, the testosterone level of painters was significantly decreased but the luteinizing hormone (LH) and follicle-stimulating hormone (FSH) levels of painters were significantly higher than controls. Occupational exposure to BPA influences testosterone and gonadotropic hormones in male workers.

• Asian-Australasian Journal of Animal Sciences
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• 제4권3호
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• pp.293-298
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• 1991

A study was conducted to determine the effect of environmental temperature and level of food intake on plasma concentration of thyroid hormones. Three dairy heifers were used in an experiment which consisted of three levels of chamber temperature (10, 20 and $30^{\circ}C$) and three levels of food intake (100, 75 and 50% of recommended requirements). The analysis showed significant effects of environmental temperature on plasma triiodothyronine concentration, rectal temperature, respiration rate and heart rate but not on heat production. The range of plasma triiodothyronine was 2.51~1.79 ng/ml when the environmental temperature varied from 10 to $30^{\circ}C$. Effects of feed intake level were significant for heart rate and heal production. Heat production decreased from 25.9 to $20.0kJ/kg^{0.75}{\cdot}h$ when the TDN intake decreased from 66.3 to $35.1g/kg^{0.75}{\cdot}d$. There was no interactive effect of environmental temperature and feed intake level. Plasma triiodothyronine concentration decreased under high environmental temperature without any changes in heat production. The effects of environmental temperature and feed intake level on the physiological function of thyroid gland, as indicated by the relative circulating rate of thyroid hormones, were found to be clear.

• 한국환경보건학회지
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• 제38권3호
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• pp.195-203
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• 2012

Objectives: This paper aims to investigate the influence on stress hormones of job stress resulting from firefighting duties, as well as the degree of such influence. Methods: KOSS-26 and stress hormones such as norepinephrine (NE), epinephrine (EPI), adrenocorticotrophic hormone (ACTH), and cortisol were analyzed for 191 male firefighters from the western area of Incheon, the Incheon Industrial Complex, and Bucheon, Korea. Job stress and stress hormones were compared between a office working group and field-working group. Results: There was no significant difference in EPI and ACTH between the two groups. Change of stress hormones prior to engaging in typical duties, following typical duties, and immediately after field activities was examined. All the EPI, ACTH, and cortisol showed statistically significant changes with time, but not NE in the blood. In the field-working group, the cortisol levels in the blood of the firefighting and rescue groups showed notable differences depending on the time at which the measurements were taken. Conclusion: The differences in stress hormone levels depending on the type of duties of the firefighters were identified. Thus, interventions proper to job requirements is required in order to ease stress.

• 한국환경보건학회지
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• 제28권4호
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• pp.17-22
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• 2002

In crustaceans, as in other arthropods, the molt cycle and the physiological process of growth are controlled by molting hormones (MH) which are steroid hormones, the ecdysteroids. Ecdysteroids are major arthropod hormones which control both development (embryonic and larval molts, metamorphosis) and reproduction. The purpose of the present study was to evaluate both fenarimol and methoprene for embryotoxicity to daphnids. The embryotoxicity associated with each compound was assessed to discern whether the embryotoxicity of methoprene might be due to ecdysone agonist and the ecdysone antagonistic effects of fenarimol on Daphnia embryo. Exposure of daphnids for three weeks to 50 M methoprene resulted in a significantly high incidence of offspring that exhibited general toxicity. This exposure concentration had significant effects on the overall number of embryo death. However, exposure to 3 or 1 $\mu$M fenarimol were no significant effects on the embryo toxicity. The incidence of both of these toxicity increased with methoprene exposure. This observation suggest that methoprene showed embryonic general toxicity during embryo development, while, only fenarimol showed weak general toxicity with early stages of embryonic development.

• 한국생명과학회:학술대회논문집
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• 한국생명과학회 2008년도 제49회 학술심포지움 및 국제학술대회
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• pp.77.2-77.2
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• 2008