• Journal of Preventive Medicine and Public Health
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• v.40 no.1
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• pp.16-22
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• 2007

Objective : The purpose of this study was to evaluate the levels of DNA damage in human lymphocytes caused by smoking and other lifestyle factors. Methods : The study population consisted of 173 normal healthy male adults from 21 to 59 years old. The demographic and lifestyle variables were obtained from administered questionnaires. The level of lymphocytic DNA damage in the peripheral blood was evaluated by the Comet assay. Statistical analyses were done by general linear model analysis and Dunnett's multiple comparison. Results : The difference in DNA damage between smokers and non-smokers was statistically significant. The means for the Tail%DNA were found to be 10.48 in the current smokers and 9.60 in the non-smokers (p < 0.05). The tail moment means were 1.58 and 1.45 (p < 0.05) for the current smokers and non-smokers, respectively. The number of cigarettes smoked per day did not result in a significant difference in the level of DNA damage among the smokers. Other lifestyle factors such as age, and drinking and exercise habits were not related to DNA damage. Conclusions : The DNA damage in the lymphocytes of smokers was found to be significantly higher than that for non-smokers. However, the number of cigarettes smoked per day was not related to DNA damage. Further study is needed to evaluate the relationship between the amount of smoking and level of damage to DNA. In addition, the status of DNA repair activities should be assessed.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.44 no.1
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• pp.19-32
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• 2024

An investigation into the detailed safety diagnosis report indicates that domestic highway bridges mainly suffer from defects, deterioration, and damage due to physical forces. In particular, deterioration is an inevitable damage that occurs due to various environmental and external factors over time. In particular, bridge deck is very vulnerable to cracks, which occur along with various types of damages such as rebar corrosion and surface delamination. Thus, this study evaluates a correlation between heterogeneous damage and deterioration environment and then identifies the main causes of such heterogeneous damage. After all, a bridge heterogeneous damage prediction model was developed using random forests to determine the top five factors contributing to the occurrence of the heterogeneous damage. The results of the study would serve as a basic data for estimating bridge maintenance and budget.

• International Journal of Automotive Technology
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• v.4 no.2
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• pp.77-86
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• 2003

How to compare the environmental damage caused by vehicles with different foe]s and drive trains\ulcorner This paper describes a methodology to assess the environmental impact of vehicles, using different approaches, and evaluating their benefits and limitations. Rating systems are analysed as tools to compare the environmental impact of vehicles, allowing decision makers to dedicate their financial and non-financial policies and support measures in function of the ecological damage. The paper is based on the "Clean Vehicles" research project, commissioned by the Brussels Capital Region via the BIM-IBGE (Brussels Institute for the Conservation of the Environment) (Van Mierlo et at., 2001). The VriJe Universiteit Brussel (ETEC) and the universite Libre do Bruxelles (CEESE) have jointly carried out the workprogramme. The most important results of this project are illustrated in this paper. First an overview of environmental, economical and technical characteristics of the different alternative fuels and drive trains is given. Afterward the basic principles to identify the environmental impact of cars are described. An outline of the considered emissions and their environmental impact leads to the definition of the calculation method, named Ecoscore. A rather simple and pragmatic approach would be stating that all alternative fuelled vehicles (LPG, CNG, EV, HEV, etc.) can be considered as ′clean′. Another basic approach is considering as ′clean′ all vehicles satisfying a stringent omission regulation like EURO IV or EEV. Such approaches however don′t tell anything about the real environmental damage of the vehicles. In the paper we describe "how should the environmental impact of vehicles be defined\ulcorner", including parameters affecting the emissions of vehicles and their influence on human beings and on the environment and "how could it be defined \ulcorner", taking into account the availability of accurate and reliable data. We take into account different damages (acid rain, photochemical air pollution, global warming. noise, etc.) and their impacts on several receptors like human beings (e.g., cancer, respiratory diseases, etc), ecosystems, or buildings. The presented methodology is based on a kind of Life Cycle Assessment (LCA) in which the contribution of all emissions to a certain damage are considered (e.g. using Exposure-Response damage function). The emissions will include oil extraction, transportation refinery, electricity production, distribution, (Well-to-Wheel approach), as well as the emission due to the production, use and dismantling of the vehicle (Cradle-to-Grave approach). The different damages will be normalized to be able to make a comparison. Hence a reference value (determined by the reference vehicle chosen) will be defined as a target value (the normalized value will thus measure a kind of Distance to Target). The contribution of the different normalized damages to a single value "Ecoscore" will be based on a panel weighting method. Some examples of the calculation of the Ecoscore for different alternative fuels and drive trains will be calculated as an illustration of the methodology.

• Structural Engineering and Mechanics
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• v.40 no.5
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• pp.719-743
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• 2011

A hybrid damage monitoring scheme using parallel acceleration-impedance approaches is proposed to detect girder damage and support damage in steel plate-girder bridges which are under ambient train-induced excitations. The hybrid scheme consists of three phases: global and local damage monitoring in parallel manner, damage occurrence alarming and local damage identification, and detailed damage estimation. In the first phase, damage occurrence in a structure is globally monitored by changes in vibration features and, at the same moment, damage occurrence in local critical members is monitored by changes in impedance features. In the second phase, the occurrence of damage is alarmed and the type of damage is locally identified by recognizing patterns of vibration and impedance features. In the final phase, the location and severity of the locally identified damage are estimated by using modal strain energy-based damage index methods. The feasibility of the proposed scheme is evaluated on a steel plate-girder bridge model which was experimentally tested under model train-induced excitations. Acceleration responses and electro-mechanical impedance signatures were measured for several damage scenarios of girder damage and support damage.

• Journal of the Korean Society for Nondestructive Testing
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• v.31 no.3
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• pp.260-270
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• 2011

The electromechanical impedance(E/M)-based method detects local structural damages based on variations of electrical impedance signatures which are obtained from piezoelectric sensors bonded to the structure and excited in high frequency band. In this method, temperature changes may result in significant impedance variations and lead to erroneous diagnostic results of the structure. To tackle this problem, a new technique providing a 2-dimensional damage feature related to the temperature information is proposed to distinguish the structural damage from the undesirable temperature variation. For experimental tests to validate the proposed method, damages are introduced by bolt loosening to a bolt-jointed steel beam, and impedance signals are measured under varying temperature conditions through a piezoelectric sensor attached on the beam. A freely suspended piezoelectric sensor is additionally utilized to obtain temperature information indirectly from resistance signatures. From a relationship between the damage index (from a constrained sensor) and the temperature (from a freely suspended sensor or a temperature sensor), damages can be detected more clearly under varying temperature compared to other conventional approaches.

• Earthquakes and Structures
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• v.18 no.1
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• pp.97-111
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• 2020

Cylindrical steel tanks are important components of industrial facilities. Their safety becomes a crucial issue since any failure may cause catastrophic consequences. The aim of the paper is to show the results of comprehensive FEM numerical investigation focused on the response of cylindrical steel tanks under mining tremors and moderate earthquakes. The effects of different levels of liquid filling, the influence of non-uniform seismic excitation as well as the aspects of diagnosis of structural damage have been investigated. The results of the modal analysis indicate that the level of liquid filling is really essential in the structural analysis leading to considerable changes in the shapes of vibration modes with a substantial reduction in the natural frequencies when the level of liquid increases. The results of seismic and paraseismic analysis indicate that the filling the tank with liquid leads to the substantial increase in the structural response underground motions. It has also been observed that the peak structural response values under mining tremors and moderate earthquakes can be comparable to each other. Moreover, the consideration of spatial effects related to seismic wave propagation leads to a considerable decrease in the structural response under non-uniform seismic excitation. Finally, the analysis of damage diagnosis in steel tanks shows that different types of damage may induce changes in the free vibration modes and values of natural frequencies.

• Environmental Analysis Health and Toxicology
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• v.19 no.1
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• pp.49-58
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• 2004

It is important to select a risk based priority area for environmental policy formation and decision-making. We estimated the health risks and associated damage costs from exposure to fine particles and assigned priority areas for twenty -five districts in Seoul. In order to estimate the theoretical mortality incidence of the health risk, baseline risks were estimated from mortality rates in two low level areas of fine particles, Seocho Gu and Cheju city To estimate the damage cost from the risk estimates, we investigated and estimated the willingness to pay (WTP) for specific risk reduction. We assumed two different locations as the reference area, Cheju city as Scenario I and Seocho gu as Scenario II. From the results, the five districts, Kwangjin, Chungnang, Kangbuk, Nowon, and Kangnam, ranked high in the categories of both health risk and economic risk. Damage costs were over twenty billion won in each of these districts. As there are uncertainties in these results, the parameter values such as PM$_{2.5}$ level, dose -response slope factor, baseline risk, exposure population and WTP should be continuously validated and refined.d.

• Smart Structures and Systems
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• v.13 no.5
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• pp.849-868
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• 2014

An indirect approach is explored for structural health bridge monitoring allowing for wide, yet cost-effective, bridge stock coverage. The detection capability of the approach is tested in a laboratory setting for three different reversible proxy types of damage scenarios: changes in the support conditions (rotational restraint), additional damping, and an added mass at the midspan. A set of frequency features is used in conjunction with a support vector machine classifier on data measured from a passing vehicle at the wheel and suspension levels, and directly from the bridge structure for comparison. For each type of damage, four levels of severity were explored. The results show that for each damage type, the classification accuracy based on data measured from the passing vehicle is, on average, as good as or better than the classification accuracy based on data measured from the bridge. Classification accuracy showed a steady trend for low (1-1.75 m/s) and high vehicle speeds (2-2.75 m/s), with a decrease of about 7% for the latter. These results show promise towards a highly mobile structural health bridge monitoring system for wide and cost-effective bridge stock coverage.

• International Journal of Concrete Structures and Materials
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• v.7 no.3
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• pp.175-182
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• 2013

A damage-based approach for the performance-based seismic assessment of reinforced concrete frame structures is proposed. A new methodology for structural damage assessment is developed that utilizes response information at the material level in each section fiber. The concept of the damage evolution is analyzed at the section level and the computed damage is calibrated with observed experimental data. The material level damage parameter is combined at the element, story and structural level through the use of weighting factors. The damage model is used to compare the performance of two typical 12-story frames that have been designed for different seismic requirements. A series of nonlinear time history analyses is carried out to extract demand measures which are then expressed as damage indices using the proposed model. A probabilistic approach is finally used to quantify the expected seismic performance of the building.

• Computers and Concrete
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• v.21 no.6
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• pp.741-748
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• 2018

In this paper, the sensitivity of a plastic-damage-based structural damage index on mesh density is studied. Multiple finite element meshes with increasing density are used to investigate their effect on the damage index values calculated from nonlinear finite element simulations for a reinforced concrete column subjected to cyclic loading. With the simulation results, this paper suggests a correction method for the objective damage index based on nonlinear regression of volumetric tensile damage ratio data. The modified damage index values are presented in the quasi-static cyclic simulation to show the efficacy of the suggested correction method.