• Journal of the Korean Institute of Landscape Architecture
• /
• v.43 no.3
• /
• pp.114-124
• /
• 2015

The concepts of activity involvement(AI) and place attachment(PA) are useful for explaining the sustainable use of natural resources by humans. Although several studies have investigated the effects of AI and PA on environmental behaviors and found its implications, it has not examined the simultaneous effects of both AI and PA. Thus, the purpose of this study was to develop a typology of both AI and PA. This typology was used to explain the environmentally responsible behaviors of visitors. The study sample surveyed 587 users of the main trail in Namhansanseong Provincial Park The results were analyzed by frequency, reliability, factor analysis, cross-tabulation, T-test, correlation and ANOVA analysis. As a result, the typology identified four subgroups of hikers based on involvement in hiking and attachment to setting. Results also indicate that environmentally responsible behaviors do vary significantly across typology. In detail, general environmental behavior and specific environmental behavior were significantly different between the four groups. These finding suggests that PA seems to play a more powerful role than AI in relation to environmental behavior. While more involved and more attached hikers were more active in environmental behaviors, less involved and less attached hikers had a more passive attitude. In this respect, this study placed emphasis on the fact that the future resource management of tourism and outdoor recreation may be established based on its activity experience in certain place.

• Asian Pacific Journal of Cancer Prevention
• /
• v.17 no.3
• /
• pp.1299-1308
• /
• 2016

Our previous studies clearly demonstrated that a combination of WP 631 and Epo B has higher activity against ovarian cancer cells than either of these compounds used separately. In order to fully understand the exact mechanism of action in combination, we assessed effects on the cell cycle of SKOV-3 cells. We evaluated three control points essential for WP 631 and Epo B action to determine which cell cycle-regulating proteins (CDK1/cyclin B complex, EpCAM or HMGB1) mediate activity. The effects of the drug on the cell cycle were measured based on the nuclear DNA content using flow cytometry. Expression of cell cycle-regulating genes was analyzed using real-time PCR. It was discovered that WP 631, at the tested concentration, did not affect the SKOV-3 cell cycle. Epo B caused significant G2/M arrest, whereas the drug combination induced stronger apoptosis and lower mitotic arrest than Epo B alone. This is very important information from the point of view of the fight against cancer, as, while mitotic arrest in Epo B-treated cells could be overcame after DNA damage repair, apoptosis which occurs after mitotic slippage in combination-treated cells is irreversible. It clearly explains the higher activity of the drug combination in comparison to Epo B alone. Epo B acts via the CDK1/cyclin B complex and has the ability to inhibit CDK1, which may be a promising strategy for ovarian cancer treatment in the future. The drug combination diminishes EpCAM and HMGB1 expression to a greater degree than either WP 631 and Epo B alone. Owing to the fact that the high expression of these two proteins is a poor prognostic factor for ovarian cancer, a decrease in their expression, observed in our studies, may result in improved efficacy of cancer therapy. The presented findings show that the combination of WP 631 and Epo B is a better therapeutic option than either of these drugs alone.

• The Korean Journal of Ecology
• /
• v.23 no.6
• /
• pp.453-460
• /
• 2000

The forest vegetation of Mt. seondal was classified into eight communities and one afforestation by the phytosocialogical method (Z-M method). In general, Quercus mongolica trees occupied most of the area, while afforestation forest was distributed on the lower slope, cultivated land, and at the vicinity of village. The vegetation on the top part of Mt. Seondal was comparatively well preserved, but that in the lower areas has been disturbed heavily by human activity and some had mixed forests composed of pine trees, oaks, ashes, and Rhododendron micrantum shrub. By cluster analysis method. nine groups were identified as follows : Quercus mongolica group, Q. mongolica - Pinus densiflora group, Q. mongolica - Rhododendron schlipen - bachii group, Q. mongolica - Symplocos chinensis for. pilosa group, P. densiflora group, Juglans mandshurica group, Fraxinus mandshurica group, Betula costata group and Larix leptolepis group. These groups showed differences in species composition, but Quercus mongolica, Q. mongolica - P. densiflora, Q. mongolica - R. schlippenbachii and Q. mongolica - S. chinensis for. pilosa groups among them showed very similar floristic composition to each other. In the relationship between polar ordination axes and environmental variables, altitude was the environmental factor determining variation in species composition along axis X and soil moisture was the environmental along axis Y. They were the main factors in determining forest vegetation. The result of cluster analysis and polar ordination for the forest vegetation were corresponded to those of phytosocialogical classification in classifying vegetation.

• Journal of the Korean Applied Science and Technology
• /
• v.28 no.3
• /
• pp.345-350
• /
• 2011

Antioxidant agent, 1,1,3-tris(2-methyl-4-hydroxy-5-tert-butylphenyl)butane were prepared and investigated the antioxidant activity on recycled rubber mat manufactured with waste tire powder. Mechanical properties of rubber mat are influenced by many factor such as compounding ingredients and state of cure, process of rubber, and fillers. Our study aim is to investigate influence of antioxidant activities on ozone cracking and the thermal aging time. In this work, the degradation of recycled rubber mat was studied and suggested mechanism to involve two-type of degradation, thermal aging and cracking both of which can be contained antioxidant or non-antioxidant agent.

• Journal of Environmental Science International
• /
• v.30 no.1
• /
• pp.45-55
• /
• 2021

In this study, the odor of the parts and the odor of the surrounding environment were classified and verified. In order to increase the reliability of odor quantitative/qualitative analysis, the selection criteria for 5 sensory evaluators were established, and the n-Butanol control solution for each odor intensity was periodically trained to recognize the odor intensity before sensory evaluation. In addition, although various odor thresholds have been used through several studies, verification of whether the odor intensity value obtained through GC/MSD analysis is similar to the degree to which a person directly smells and feels it. It is important to select the odor threshold that has the best correlation with the odor intensity calculated by the person smelling the odor. Finally, sampling and measuring flowing airflow and temporary odors such as odor component analysis was experimentally difficult due to limited collection space and differences in concentration of generated components. In this study, a quantitative analysis was made possible by using the low temperature concentration (cooling) trap method. Through this, it was confirmed that the correlation with the actual odor intensity was not caused by the product itself, but by the environmental factor discharged from the product after creating the odor environment.

• Journal of Korean Academy of Nursing Administration
• /
• v.6 no.2
• /
• pp.259-279
• /
• 2000

This study is a descriptive analytic research measuring nursing service quality, using SERVQUAL model, to make fundamental data and strategies for nursing service improvement. Data were collected by self-reported questionnaire from 202 patients and 142 nurses, from June 7 to 14, 1999. The reliability of instrument were adequate(Cronbach ${\alpha}=.94$). SAS program was utilized for statistical analysis of collected data. The results were as follows; 1. There was a gab between patient's expectation and perception on nursing service(Gap B). Gap D was indicated an affecting factor to decide nursing service quality. Gap C was indicated an indirect affecting factor of nursing service quality. Because it was not statistically significant in total item analysis, but in individual item analysis, 7 items were appeared statistically significant. Gap A was not a gap occurrence factor of nursing service quality. 2. Focuses of nursing service quality improvement strategies were; (1) to direct qualitative improvement of nursing service in order to correspondence patient's nursing service expectation. (2) to make nurse's service activity modified because nurse's practice were not reached patient's expectation level. (3) to need internal, external factor analysis affecting nurse's service activity. 3. Nursing service quality was decided by rather environmental inappropriateness provided nursing service than itself. Therefore, to make nursing service quality improvement, it is required to improve nursing service environment. For this, followings are required; (1) to strengthen nurse's education on lower part of nursing service satisfaction and QI activities. (2) to balance demand and supply of nursing personnel. 3) to fix computerized system for reducing other duties weight except nursing care through analysis of nursing activity. (4) to construct rational cooperating system among related departments. 4. The important parts for nursing service quality improvement were indicated as follows: (1) Gap B: 'prompt reaction', 'examination symptom before patient's complaint', 'hearted nursing service reducing patient's dissatisfaction', 'explanation goals of nursing activities', 'having special Knowledge enough', 'maintenance position comfortably', 'management of patient's physical hygiene'. (2) Gap C: 'maintenance physical safety', 'explanation about hospital rules and facilities'. (3) Gap D: 'tender, safe injection and wound care'. Because above items are mostly improved through nurse's attitude change and quality improvement, it is required to establish nursing standardization and to strengthen nurse's clinical education. As the based on above results, followings are suggested; 1. SERVQUAL model is very useful to make strategies for nursing service quality improvement because it indicates multiple factors affecting hap occurrence. 2. At individual items analysis of Gap C, statistically significant 7 items appeared higher nurse's perception level than patient's perception level on nursing service were trouble perception level on nursing service quality improvement. So. it need further research to analysis about these difference occurring factors. 3. At analysis of Gap D, it is indicated that in nursing service performance process, multiple factors lowing nursing service quality were intruded. So it needs further research to analysis what these factors are and how each factors affect on nursing performance process. 4. nursing service quality measurement is changeable according to sample select time or sampled subject's characteristics. So to develope strategy for nursing service quality improvement is based on the results of periodical analysis.

• Journal of Korean Society of Forest Science
• /
• v.77 no.4
• /
• pp.401-413
• /
• 1988

To investigate the users' activity, impact and psychology in Naejang Temple district at Mt. Naejang National Park in Korea, users' density and questionnaire survey at three major picnic areas and passenger counting at major pass were executed and environmental impacton on the site was surveyed. The total number of visitors showed stability at the level of one million persons every year after 1984. Users' impact was much severe along the main trail, the upper cablecar station and the slope from the observatory to Keumsun Valley, The maximum momentary number of users was estimated as 53,000 persons in autumn. Approximately 20% of the total number of visitor used Keumsun Valley and Weonjeok Valley area and 80% of visitors left after using only grassland and cablecar. The visitors' characteristics was similiar to the type of long-distanced national park and the main visiting purpose was to see autumn leaves. The psychological satisfaction did not very significantly as to increasing user's speace. As a result of varimax rotated factor analysis, the 1st factor, most affecting users' psychological satisfaction, was related to landscape and consisted of nature disturbance, crowdedness, noisiness, cleanness, in order of importance. The 2nd factor was related to facilities and consisted of number of toilet, number of waste-baskets, amount of drinking water, safety, in order of importance.

• BMB Reports
• /
• v.53 no.10
• /
• pp.521-526
• /
• 2020

Endogenous retroviruses (ERVs) are retrotransposons present in various metazoan genomes and have been implicated in metazoan evolution as well as in nematodes and humans. The long terminal repeat (LTR) retrotransposons contain several regulatory sequences including promoters and enhancers that regulate endogenous gene expression and thereby control organismal development and response to environmental change. ERVs including the LTR retrotransposons constitute 8% of the human genome and less than 0.6% of the Caenorhabditis elegans (C. elegans) genome, a nematode genetic model system. To investigate the evolutionarily conserved mechanism behind the transcriptional activity of retrotransposons, we generated a transgenic worm model driving green fluorescent protein (GFP) expression using Human endogenous retroviruses (HERV)-K LTR as a promoter. The promoter activity of HERV-K LTR was robust and fluorescence was observed in various tissues throughout the developmental process. Interestingly, persistent GFP expression was specifically detected in the adult vulva muscle. Using deletion constructs, we found that the region from positions 675 to 868 containing the TATA box was necessary for promoter activity driving gene expression in the vulva. Interestingly, we found that the promoter activity of the LTR was dependent on che-1 transcription factor, a sensory neuron driver, and lin-15b, a negative regulator of RNAi and germline gene expression. These results suggest evolutionary conservation of the LTR retrotransposon activity in transcriptional regulation as well as the possibility of che-1 function in non-neuronal tissues.

• Journal of Biomedical and Translational Research
• /
• v.19 no.4
• /
• pp.92-102
• /
• 2018

The objectives of this study were to find out the plant to enhance immune activity among 42 kinds of foods frequently consumed by the Korean elderly consisting of 5 food groups and 5 wild plants. Each sample was assessed the immunoactive effect by measuring $NF-{\kappa}B/AP1$ gene expression, nitric oxide and cytokine production in $RAW-Blue^{TM}$ cell. Soybean sprouts of 47 plants showed the highest $NF-{\kappa}B/AP1$ gene expression at the level of $1.13{\pm}0.03$ (O.D. 650 nm) and Soritae, sweet potato, banana, apple, garlic, crown daisy, cabbage and Ailanthus altissima also had high activity of $NF-{\kappa}B/AP1$ gene in $RAW-Blue^{TM}$ cell stimulated by LPS. NO production of Ailanthus altissima was significantly higher than that of other plants and 16 plants of glutinous sorghum, black rice, Seoritae, Heuktae, sweet potato, banana, apple, garlic, mungbean sprouts, spinach, crown daisy, young pumpkin, cabbage, soybean sprouts, Actinidia arguta and Aster scaber were the next best activity. The above results selected 17 out of 47 plant samples. Moreover, soybean sprouts was significantly shown to increase $TNF-{\alpha}$ ($1,509.55{\pm}1.38pg/mL$) and $IL-1{\beta}$ ($54.56{\pm}1.08pg/mL$) cytokines in comparison with RAW-Blue cell stimulated by LPS. According to the results of in vitro evaluation, the ethanol extract of soybean sprout increased the production of immune-enhancing cytokines by proliferation of macrophages. In addition, $NF-{\kappa}B$ transcription factor activity and NO production ability were excellent, and it was selected as a material having excellent immunological activity.

• Journal of The Korean Society of Agricultural Engineers
• /
• v.65 no.5
• /
• pp.69-80
• /
• 2023

Carbon neutrality in agriculture can be derived from systematic GHG reduction policies based on quantitative environmental impact analysis of GHG-emitting activities. This study is to explore how to advance the calculation of carbon emissions from agricultural activities to the detailed spatial level to a spatial Tier 3 level (Tier 2.5 level), methodologically beyond the Tier 2 approach. To estimate the GHG emissions beyond the Tier 2.5 level by region for detailed spatial units, we constructed available activity data on carbon emission impact factors such as rice cultivation, agricultural land use, and livestock. We also built and verified detailed data on emission activities at the field level through field surveys. The GHG emissions were estimated by applying the latest national emission factors and regional emission factors according to the IPCC 2019 GL based on the field-level activity data. This study has significance that it explored ways to build activity data and calculate GHG emissions through statistical data and field surveys based on parcels, one of the smallest spatial units for regional carbon reduction strategies. It is expected that by utilizing the activity data surveyed for each field and the emission factor considering the activity characteristics, it will be possible to improve the accuracy of GHG emission calculation and quantitatively evaluate the effect of applying reduction policies.