• Journal of the Society of Naval Architects of Korea
• /
• v.53 no.6
• /
• pp.503-513
• /
• 2016

In order to reduce the green-house gas exhaustion, International Maritime Organization (IMO) has been reinforcing carbon gas regulations. Due to the regulations, a lot of competitions for designing Eco ship in the shipbuilding industry are progressing now. It is faced with the necessity of reducing hull weight by combining automated systems for optimal compartment arrangement with hull structural design. Most researches on optimum structural design method have been consistently in progress and applied to minimize weight and cost of mid-ship section in preliminary ship design stage based on analytical structural analysis method on fixed compartment arrangement. In order to reduce design period and to improve international technical competitiveness by shortening the period of hull structural design and enhancing design accuracy, it has been felt necessity to combine optimized compartment arrangement with optimum design of ship structure based on the international regulations and rules. So in this study, the automated design algorithm for longitudinal members has been developed to combine automated algorithm of compartment arrangement with hull structural design system for oil tanker. The SeaTrust-Hullscan software developed by Korean Register is used to perform ship structural design for mother ship and selected design cases. The effect of weight reduction is verified with comparison of ship weight between mother ship and the cases suggested in this study.

• Journal of the Society of Cosmetic Scientists of Korea
• /
• v.42 no.2
• /
• pp.119-126
• /
• 2016

Skin is the largest organ that protects the body from the external environmental factors such as smog, cigarette smoke, UV. Protective skin barrier is composed with keratinizational keratinocytes and intercellular lipids such as ceramides, cholesterols and fatty acids combined by the lamellar liquid crystal structure. In this research, we confirmed that the Jeju wild ginseng (JWG) extracts dose-dependently increased the expression of serine-palmitoyltransferase (SPT) protein which is associated with ceramide biosynthesis. In addition, emulsion containing 5% JWG extract was applied on skin of human volunteers for 2 weeks and then significantly reduced transepidermal water loss (TEWL) compared to that of control group. As a results, JWG extract increased the biosynthesis of ceramides that is the key components of the skin lipid through enhancing expression of SPT. In addition, JWG extract reduced TEWL resulting in improvement of skin barrier function. In this context, we suggest that JWG extract could be used as a skin barrier enhancer and moisturing agents in cosmetic fileds.

• Journal of the Korea Society of Computer and Information
• /
• v.19 no.11
• /
• pp.193-202
• /
• 2014

This study was attempted in order to measure the level of Korean people's social capital and their multicultural acceptance, and to explain the relationship between the sub-factors of social capital(trust, reciprocity, and participation) and the multicultural acceptance. Furthermore, this study aimed to examine the relative influence of the sub-factors of social capital on the multicultural acceptance and to suggest which social capitals should be reinforced. Data on 'social capital' and 'multicultural acceptance' used in this study were obtained from the data of the 8th Korean General Social Survey (KGSS) in 2010. The results of analyses are as follows. First, social capital was lower with increase in age (F=28.18, p<.001), and higher with increase in academic qualification (F=15.49, p<.001), and total household income (F=8.85, p<.001). Second, the multicultural acceptance was higher in men (t=9.98, p<01) and lower with increase in age (F=27.29, p<.001), and higher with increase in academic qualification (F=28.99, p<.001), and total household income (F=11.92, p<.001). Third, among the three social capital factors influencing the multicultural acceptance, 'trust' was found to have a significant positive (+) effect. Based on these results were suggested various strategies for enhancing Korean people's multicultural acceptance.

• Food Science and Preservation
• /
• v.6 no.4
• /
• pp.514-520
• /
• 1999

Changes in pH, titratable acidity, CO$_2$production, reducing sugar, and lactic acid bacteria of fresh kimchi juice supplemented with combinations of 3 lactic acid bacteria and germanium(Ge)-132 or fructooligosaccharide(FO) during fermentation at 30$^{\circ}C$ were investigated to assess the potential for extending the shelf life and enhancing the functional properties in kimchi. In kimchi juice containing Ge-132, sample(I) (inoculated with a mixture of bacteriocin-producing SNF-13 strain and E. faecium) exhibited that the amounts of organic acid and evolved CO$_2$gas were lower than those of the other starter samples(II-IV). The growth of lactic acid bacteria naturally present in kimchi juice, particularly Lb. plantarum and Leu. mesentroides, may be inhibited due to competition of the isolated SNF-13 strain and E. faecium by Ge-132. During fermentation of kimchi juice containing FO sugar, the contents of organic acid and evolved CO$_2$gas On juice broth with 4 starters were predominantly higher than those of control and Ge-132 groups, and then the growth of lactic acid bacteria originated from kimchi ingredients was thought to be markedly accelerated. Our results indicated that functional properties like the extension of shelf life and increase of biological activity in kimchi were enhanced by adding Ge-132 and bacterium-producing lactic acid bacterium, which were resistant to organic acid and stimulated by Ge-132.

• Journal of Veterinary Science
• /
• v.22 no.5
• /
• pp.63.1-63.14
• /
• 2021

Background: Recently, mesenchymal stem cells therapy has been performed in dogs, although the outcome is not always favorable. Objectives: To investigate the therapeutic efficacy of mesenchymal stem cells (MSCs) using dog leukocyte antigen (DLA) matching between the donor and recipient in vitro. Methods: Canine adipose-derived MSCs (cA-MSCs) isolated from the subcutaneous tissue of Dog 1 underwent characterization. For major DLA genotyping (DQA1, DQB1, and DRB1), peripheral blood mononuclear cells (PBMCs) from two dogs (Dogs 1 and 2) were analyzed by direct sequencing of polymerase chain reaction (PCR) products. The cA-MSCs were co-cultured at a 1:10 ratio with activated PBMCs (DLA matching or mismatching) for 3 days and analyzed for immunosuppressive (IDO, PTGS2, and PTGES), inflammatory (IL6 and IL10), and apoptotic genes (CASP8, BAX, TP53, and BCL2) by quantitative real-time reverse transcriptase-PCR. Results: cA-MSCs were expressed cell surface markers such as CD90⁺/44⁺/29⁺/45^- and differentiated into osteocytes, chondrocytes, and adipocytes in vitro. According to the Immuno Polymorphism Database, DLA genotyping comparisons of Dogs 1 and 2 revealed complete differences in genes DQA1, DQB1, and DRB1. In the co-culturing of cA-MSCs and PBMCs, DLA mismatch between the two cell types induced a significant increase in the expression of immunosuppressive (IDO/PTGS2) and apoptotic (CASP8/BAX) genes. Conclusions: The administration of cA-MSCs matching the recipient DLA type can alleviate the need to regulate excessive immunosuppressive responses associated with genes, such as IDO and PTGES. Furthermore, easy and reliable DLA genotyping technology is required because of the high degree of genetic polymorphisms of DQA1, DQB1, and DRB1 and the low readability of DLA 88.

• Journal of the Korean Recycled Construction Resources Institute
• /
• v.9 no.3
• /
• pp.236-245
• /
• 2021

It is very important for structure designer to understand the service life variation since a wide range of service life is evaluated with changing exposure conditions and design parameters. Recently, for zero-carbon, waste plastic has been used for fuel for clinker production and this yields increase in chloride content in cement. This study is for evaluation of changing service life in the concrete with increasing initial chloride content due to usage of plastic-SRF(Solid Refuse Fuel) considering various exposure conditions and design parameters. For this, 4 levels of initial chloride content were assumed, and the service life was assessed using LIFE 365 program considering various environmental conditions including 3 levels of surface chloride content. As for analysis parameters, critical/initial chloride content, blast furnace slag powder replacement ratio, W/B(Water to Binder) ratio, cover depth, and unit mass for binder are adopted. Service life decreases with increasing initial chloride content and a significant reduction of service life is not evaluated permitting up to 1,000ppm of initial chloride content. With increasing slag replacement ratio, a longer service life can be secured since blast furnace slag powder has the effect of reducing the diffusion of external chloride ions and fixing the free chloride. It is thought that increasing initial chloride content up to European standard is helpful for enhancing sustainability and reducing carbon emission. Though the reduction in service life due to an increase in the initial chloride content is not significant in slag-concrete with low surface chloride content, careful consideration for mixing design should be paid for the exposure environment with high surface chloride content.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.22 no.4
• /
• pp.473-482
• /
• 2021

The introduction of automated flight systems has greatly improved aviation safety, but aircraft pilots continue to face new challenges. The pilot's stress from an aeronautical perspective can be distinguished by the 'Startle and Surprise' responses. 'Startle' is a short, strong physiological response to sudden or threatening stimuli such as unexpected gunfire. 'Surprise' is a cognitive-emotional response to an event that goes beyond one's expectations. In Martin et al.'s (2012) Startle Effect Experiment, the pilot identified physiological responses in the 'Startle' state, including delayed response and increased heart rate. In the Rahim (2020) Startle/Surprise experiment, the pilot's breathing rate and pulse rate did not change due to pre-planned emergency training. On the other hand, it was confirmed that the pilot's respiratory and heart rate were greatly increased due to the complicated aircraft and unplanned emergencies. Based on the results of these experiments, domestic pilots need to be trained to handle non-technical and various unexpected emergencies that could arise in an aircraft, rather than be just put through courses for enhancing technical capabilities or simple repetitive training as required by aviation law.

• Journal of Microbiology and Biotechnology
• /
• v.29 no.7
• /
• pp.1083-1095
• /
• 2019

Butyrate is known to play a significant role in energy metabolism and regulating genomic activities that influence rumen nutrition utilization and function. Thus, this study investigated the effects of an isolated butyrate-producing bacteria, Clostridium saccharobutylicum, in rumen butyrate production, fermentation parameters and microbial population in Holstein-Friesian cow. An isolated butyrate-producing bacterium from the ruminal fluid of a Holstein-Friesian cow was identified and characterized as Clostridium saccharobutylicum RNAL841125 using 16S rRNA gene sequencing and phylogenetic analyses. The bacterium was evaluated on its effects as supplement on in vitro rumen fermentation and microbial population. Supplementation with $10^6CFU/ml$ Clostridium saccharobutylicum increased (p < 0.05) microbial crude protein, butyrate and total volatile fatty acids concentration but had no significant effect on $NH_3-N$ at 24 h incubation. Butyrate and total VFA concentrations were higher (p < 0.05) in supplementation with $10^6CFU/ml$ Clostridium saccharobutylicum compared with control, with no differences observed for total gas production, $NH_3-N$ and propionate concentration. However, as the inclusion rate (CFU/ml) of C. saccharobutylicum was increased, reduction of rumen fermentation values was observed. Furthermore, butyrate-producing bacteria and Fibrobacter succinogenes population in the rumen increased in response with supplementation of C. saccharobutylicum, while no differences in the population in total bacteria, protozoa and fungi were observed among treatments. Overall, our study suggests that supplementation with $10^6CFU/ml$ C. saccharobutylicum has the potential to improve ruminal fermentation through increased concentrations of butyrate and total volatile fatty acid, and enhanced population of butyrate-producing bacteria and cellulolytic bacteria F. succinogenes.

• Journal of the Society of Cosmetic Scientists of Korea
• /
• v.45 no.2
• /
• pp.139-150
• /
• 2019

This study is investigated sunscreen formulation that enhances UV absorption efficiency by UV light. Ethylhexyl methoxycinnamate (OMC) is one of the most common UV filters. Many studies have been conducted about photostability of OMC. It is well known that under the UV exposure, trans-OMC could turn to cis-OMC, or produce various photoproducts including its dimers. Those chemical structure changes were understood as the reason of a decrease in UV absorption efficiency upon UV exposure. However, it was found that OMC and isoamyl p-methoxycinnamate (IMC) could even enhance its UV absorption efficiency when it was exposed to UV light in an environment similar to actual use. In order to develop sunscreen formulation that enhances UV absorption efficiency by UV light, emollient with high polarity and compatibility should be avoided from the formular. Those emollient seemed to prevent OMC or IMC from producing photoproducts under UV light. Finally, a sunscreen formulation (UV sensing SPF boosting formular) enhancing UV absorption efficiency by UV was developed by the UV activated SPF boosting technology, and the effect of the sunscreen was evaluated. in vitro SPF of the sunscreen was increased from 50.69 to 72.33 when it was exposed to UV light and its in vivo SPF (53.7) was 56.10% higher than that of the control sunscreen (below 34.4).

• The Journal of the Korea Contents Association
• /
• v.19 no.3
• /
• pp.336-348
• /
• 2019

This study aimed to verify the effects of design thinking-based team project learning on nursing college students' empathy and proactivity of problem solving. This study also examined the subjects' experiences obtained from participating in team project activity through reflective analysis. The research was a one-group, pre-and-posttest design. The subjects were 64 seniors majoring in nursing studies in N university who had attended the course of nursing management practice. During the course, they participated in a design thinking team project for a total of 10 sessions for two weeks, five times per week, and one and a half hour per day. Data was analyzed using SPSS Win 22.0, a paired t-test was conducted and Pearson's correlation coefficients were calculated. Content analysis was carried out on their experiences obtained from participation in team project activity. The subjects' empathy(t=-2.94, p=.005) and proactivity of problem solving(t=-6.23, p<.001) showed statistically significant difference between before and after the design thinking-based team project learning and had significant positive correlation(r=.634, p<.001). Analysis of team reflection revealed four themes: design thinking, empathy, problem solving ability, and critical thinking. This study verified that design thinking-based team project learning was very effective in developing nursing college students' empathy and proactivity of problem solving. Research Results Design Thinking Based on team learning, project learning is an effective teaching learning method for finding and defining customer needs, creating a solution to problems, and enhancing engagement and empathy through various stakeholder collaborations I could.