• Asian Pacific Journal of Cancer Prevention
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• v.13 no.10
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• pp.5257-5261
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• 2012

Background: High incidence of breast cancer and its fatal effect has reached an alarming stage across the globe, including the third world countries. Many factors have been reported to be associated with the development of breast cancer but detailed structural and functional information is missing. CA 15-3 is one of the known potential tumor marker of breast cancer; however little is known about structure and functional site of this protein. Present study aims to investigate the functional role of CA 15-3 in breast cancer, especially in development and metastasis. Material and Methods: Hundred female breast cancer patients confirmed by histopathological reports were included in the study. Their physiological characters were recorded in a performa. Enzyme linked immunosorbent assay (ELISA) technique was used to estimate serum CA 15-3 level. Immunohistochemistry was done for estrogen (ER), progesterone (PR) and Her2/neu receptors expression. Results: The study revealed the details of physiological characteristics of female breast cancer. Mean age was $37.72{\pm}5.99$ and $55.05{\pm}7.28$ years and serum CA 15-3 (MUC1) level was $60.47{\pm}8.59$ and $63.17{\pm}4.58$ U/ml in pre and post-menopause respectively, and both groups of women had sedentary life style. Their receptor status especially of progesterone, estrogen and HER-2/neu were positive in 50% of premenopausal women and 65% of postmenopausal women. Conclusion: There are multiple physiological factors promoting breast cancer. High serum CA 15-3 level and hormonal imbalance of ER, PR and Her2/neu appears to be the main cause of breast cancer. It may be possible that the functional sites of these proteins may be altered which may increase the chances of metastasis in breast cancer.

• Journal of Korean Society for Atmospheric Environment
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• v.25 no.4
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• pp.275-288
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• 2009

The Korean government strengthened the environmental polices to manage and enhance Metropolitan Area air quality, and also has enforced "Special Act on Seoul Metropolitan Air Quality Improvement (SASMAQI)" issued in Dec. 2004. Recently government expanded the Seoul Metropolitan Air Quality Management District (SMAQMD) to the outskirts satellite cities of Seoul area through the "Revised Law Draft of SASMAQI". The SMAQMD has been alloted the allowable emission loads to the local governments on the basis of the carrying $PM_{10}$ capacity. However, in order to establish the effective air quality control strategy for $PM_{10}$, it is necessary to understand the corresponding sources which have a potential to directly impact ambient $PM_{10}$ concentration. To deal with the situations, many receptor methodologies have been developed to identify the origins of pollutants and to determine the contributions of sources of interests. The objective of this study was to extensively identify $PM_{10}$ sources and to estimate their contributions at the metropolitan area. $PM_{10}$ samples were simultaneously collected at the 3 semi-industrialized local cities in the Seoul metropolitan area such as Hwasung-si, Paju-si, and Icheon-si sites from April 15 to May 31, 2007. The samples collected on the teflon membrane filter by one $PM_{10}$ cyclone sampler were analyzed for trace metals and soluble ions and samples on the quartz fiber filter by another sampler were analyzed for OC and EC. Source apportionment study was then performed by using a positive matrix factorization (PMF) receptor model. A total of 6 sources were identified and their contributions were estimated in each monitoring site. Contribution results on Hwasung, Paju, and Icheon sites were as follows: 33%, 27%, and 27% from soil source, 26%, 26%, and 21% from secondary aerosol source, 11%, 11%, and 12% from biomass burning, 12%, 6%, and 5% from sea salt, 7%, 15%, and 19% from industrial related source, and finally 11%, 15%, and 16% from mobile and oil complex source, respectively. This study provides information on the major sources affecting air quality in the receptor sites and thus it will help to manage the ambient air quality in the metropolitan area by establishing reasonable control strategies, especially for the anthropogenic emission sources.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.21 no.1
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• pp.768-773
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• 2020

In large-scale land development for the rational use and management of national land resources, the use of geospatial information is essential for the efficient management of projects. Recently, drone LiDAR (Light Detection And Ranging) has attracted attention as an effective geospatial information construction technique for large-scale development areas, such as housing site construction and open-pit mines. Drone LiDAR can be classified into a method using SLAM (Simultaneous Localization And Mapping) technology and a GNSS (Global Navigation Satellite System)/IMU (Inertial Measurement Unit) method. On the other hand, there is a lack of analytical research on the application of drone LiDAR or the characteristics of each method. Therefore, in this study, data acquisition, processing, and analysis using SLAM and GNSS/IMU type drone LiDAR were performed, and the characteristics and utilization of each were evaluated. As a result, the height direction accuracy of drone LiDAR was -0.052~0.044m, which satisfies the allowable accuracy of geospatial information for mapping. In addition, the characteristics of each method were presented through a comparison of data acquisition and processing. Geospatial information constructed through drone LiDAR can be used in several ways, such as measuring the distance, area, and inclination. Based on such information, it is possible to evaluate the safety of large-scale development areas, and this method is expected to be utilized in the future.

• Journal of Korea Water Resources Association
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• v.44 no.12
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• pp.929-940
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• 2011

In this study, the future expected discharges are analyzed for Daecheong and Yongdam Dam Watershed in Geum River watershed using A1B scenario based RCM with 27 km spatial resolutions from Korea Meteorological Agency and SWAT model. The direct use of GCM and RCM data for water resources impact assessment is practically hard because the spatial and temporal scales are different. In this study, the problems of spatial and temporal scales were settled by the spatial and temporal downscaling from watershed scale to weather station scale and from monthly to daily of RCM grid data. To generate the detailed hydrologic scenarios of the watershed scale, the multi-site non-stationary downscaling method was used to examine the fluctuations of rainfall events according to the future climate change with considerations of non-stationary. The similarity between simulation and observation results of inflows and discharges at the Yongdam Dam and Daecheong Dam was respectively 90.1% and 84.3% which shows a good agreement with observed data using SWAT model from 2001 to 2006. The analysis period of climate change was selected for 80 years from 2011 to 2090 and the discharges are increased 6% in periods of 2011~2030. The seasonal patterns of discharges will be different from the present precipitation patterns because the simulated discharge of summer was decreased and the discharge of fall was increased.

• Journal of Korea Water Resources Association
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• v.41 no.9
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• pp.943-958
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• 2008

This study employs Bayesian regression analysis for fitting discharge rating curves. The parameter estimates using the Bayesian regression analysis were compared to ordinary least square method using the t-distribution. In these comparisons, the mean values from the t-distribution and the Bayesian regression are not significantly different. However, the difference between upper and lower limits are remarkably reduced with the Bayesian regression. Therefore, from the point of view of uncertainty analysis, the Bayesian regression is more attractive than the conventional method based on a t-distribution because the data size at the site of interest is typically insufficient to estimate the parameters in rating curve. The merits and demerits of the two types of estimation methods are analyzed through the statistical simulation considering heteroscedasticity. The validation of the Bayesian regression is also performed using real stage-discharge data which were observed at 5 gauges on the Anyangcheon basin. Because the true parameters at 5 gauges are unknown, the quantitative accuracy of the Bayesian regression can not be assessed. However, it can be suggested that the uncertainty in rating curves at 5 gauges be reduced by Bayesian regression.

• Journal of Korea Water Resources Association
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• v.41 no.8
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• pp.845-854
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• 2008

The old bridge of Woljeong-gyo, which has the fluvial history and culture, represents the ancient construction and civil engineering techniques. It is the oldest stone bridge in Korea and currently restored with its vicinities. In this study, the experimental model was used to analyze the hydraulic characteristics, the local pier-scour depth without scour protection, and the stability of riprap protection using the old grid type panels and stones for Woljeong-gyo of the study area. The water levels were increased around 30cm due to the restored bridge piers and foundations and the effects went up to 200m upstream. The maximum scour depth of 5.4m was measured and the scour protection tests were performed with the riprap size calculated using empirical equations and the existing scour protection range. The riprap of the existing scour protection in the upstream side was broken away, while the riprap of extended scour protection was very stable for the design flood condition of Woljeong-gyo area.

• Journal of Korea Water Resources Association
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• v.48 no.1
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• pp.9-21
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• 2015

This study examined pollution level of sediment in Sookchun lake, and studied dredging validity by examining phosphorous release characteristics on surface polluted soil. Total phosphorous, the principal cause of algal blooms, exceeded dredging assessment standards regarding Daechung lake (1.5 mg/g) at all points. Also at all points, total nitrogen exceeded the dredging assessment standard regarding Paldang Lake (1.1 mg/g), but fell short of the standard regarding Daechung lake (3.0 mg/g). Dredging zone was suggested in this study is Chuso water body (WS-6~WS-12) in Sookchun lake. In relation to sediment pollution levels measured at different depths, LOI tended to decrease as it became deeper. The concentrations of T-N varied depending upon the depth as well as points, but no regular pattern was observed. The depth and site did not significantly influence T-P. From the results of phosphorous release tests, it was shown that total phosphorous release flux was calculated to be $7.2{\sim}15.4mg/m^2/d$ for anaerobic condition, $0.5{\sim}2.0mg/m^2/d$ for aerobic condition and $2.0{\sim}4.1mg/m^2/d$ for facultative condition. Release flux and T-P concentration of surface sediments had positive correlation ($R^2$ 0.7871). And The corelation between release flux and DO condition in reactor had strong negative correlation ($R^2$ 0.8824).

• Journal of Internet of Things and Convergence
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• v.6 no.3
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• pp.67-73
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• 2020

The research status of endangered amphibians in Korea was mainly studied the life-cycle and distribution status of species from the 1980s to the early 2000s. Although a relatively diverse range of studies have been conducted on mackerels, studies on habitat prediction, analysis, change and management are insufficient. WEB, which provides biota information using location information in Korea, is a site operated by the National Bio Resource Center under the Ministry of Environment, but there is no information on endangered species and general species information has also been found to be very scantily. For this research, we secured a database of location information of Narrow-mouth frog, an endangered species, by combining literature and field research, and established a system by applying new technologies and open-based platform technologies that can be easily accessed by non-technical personnel of IT among IT technologies. The system was divided into administrator functions and user functions to prevent indiscriminate sharing of information through authentication procedures through user membership of users. The established system was authorized to show the distance between the current location and the location of the Narrow-mouth frog. Considering the ecological characteristics of the Narrow-mouth frog, which is an endangered species, a radius of 500m was marked to determine the habitat range. The system is expected to be applied to the legal system to change existing protected areas, etc. and to select new ones. It is estimated that practical reduction measures can be derived by utilizing the development plan for reviewing the natural environment. In addition, the deployed system has the advantage of being able to apply to a wide variety of endangered species by modifying the information entered.

• Journal of the Korea Institute of Building Construction
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• v.10 no.5
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• pp.11-20
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• 2010

With the amendment to the Building Act in November of 2005 that offered incentives in terms of floor area ratio and number of stories to apartment buildings adopting the Rahmen structure to facilitate remodeling, the construction industry is paying more attention to PC structures. As connections between PC columns and beams require complex design, it is very difficult to install and remove forms. Since forms made of plywood for such connections are fabricated and installed on site, a significant amount of labor is required, and constructability is low. Furthermore, after concrete casting, the forms are removed in a state in which they cannot be recycled, which leads to a significant amount of construction waste. For this reason, a solution to address such issues needs to be studied. However, many researchers have focused only on the structural performance of PC structures in Korea and elsewhere, ignoring the need for research on the forms used in building PC structure connections. Therefore, this research aims to develop a form that can improve the productivity of PC structure connection construction, and compare it with conventional forms to highlight its contribution to gains in productivity and economic viability.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.39B no.6
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• pp.333-340
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• 2014

Despite the security weakness of reusing passwords, many Internet users are likely to use a single ID and password on various sites to avoid the inconvenience of remembering multiple credentials. This paper proposes a scheme for securely storing, retrieving, and updating randomly chosen (ID, password) pairs by using smart cards as secure and portable storages. The scheme makes a user free from remembering her (ID, password) pairs for Internet accesses. By splitting and scattering the (ID, password) pairs of a user across the user's smart card memory and a remote server's storage, it can protect the logon credentials even from the theft or loss of the smart card. Also, a user, if deemed necessary, can issue and let the server to delete all information belonging to the user. Hence even an attacker who cracked the smart card memory would not be able to obtain any (ID, password) pair of the victim thereafter. The scheme requires a user to input a site information and pass-phrase to her smart card to obtain the logon credentials, but it should be an acceptable overhead considering the benefits of not remembering the freely chosen (ID, password) pairs at all.