• Title/Summary/Keyword: emission computed

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Are There Any Additional Benefits to Performing Positron Emission Tomography/Computed Tomography Scans and Brain Magnetic Resonance Imaging on Patients with Ground-Glass Nodules Prior to Surgery?

  • Song, Jae-Uk;Song, Junwhi;Lee, Kyung Jong;Kim, Hojoong;Kwon, O Jung;Choi, Joon Young;Kim, Jhingook;Han, Joungho;Um, Sang-Won
    • Tuberculosis and Respiratory Diseases
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    • v.80 no.4
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    • pp.368-376
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    • 2017
  • Background: A ground-glass nodule (GGN) represents early-stage lung adenocarcinoma. However, there is still no consensus for preoperative staging of GGNs. Therefore, we evaluated the need for the routine use of positron emission tomography/computed tomography (PET)/computed tomography (CT) scans and brain magnetic resonance imaging (MRI) during staging. Methods: A retrospective analysis was undertaken in 72 patients with 74 GGNs of less than 3 cm in diameter, which were confirmed via surgery as malignancy, at the Samsung Medical Center between May 2010 and December 2011. Results: The median age of the patients was 59 years. The median GGN diameter was 18 mm. Pure and part-solid GGNs were identified in 35 (47.3%) and 39 (52.7%) cases, respectively. No mediastinal or distant metastasis was observed in these patients. In preoperative staging, all of the 74 GGNs were categorized as stage IA via chest CT scans. Additional PET/CT scans and brain MRIs classified 71 GGNs as stage IA, one as stage IIIA, and two as stage IV. However, surgery and additional diagnostic work-ups for abnormal findings from PET/CT scans classified 70 GGNs as stage IA, three as stage IB, and one as stage IIA. The chest CT scans did not differ from the combined modality of PET/CT scans and brain MRIs for the determination of the overall stage (94.6% vs. 90.5%; kappa value, 0.712). Conclusion: PET/CT scans in combination with brain MRIs have no additional benefit for the staging of patients with GGN lung adenocarcinoma before surgery.

Ictal single-photon emission computed tomography with slow dye injection for determining primary epileptic foci in infantile spasms (영아연축에서 추적자의 느린 점적주사를 이용한 발작기 SPECT)

  • Hur, Yun Jung;Lee, Joon Soo;Kang, Hoon Chul;Park, Hye Jung;Yun, Mi Jin;Kim, Heung Dong
    • Clinical and Experimental Pediatrics
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    • v.52 no.7
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    • pp.804-810
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    • 2009
  • Purpose : We investigated whether ictal single-photon emission computed tomography (SPECT) with prolonged injection of technetium-99m (99mTc) ethyl cysteinate dimer during repeated spasms can localize the epileptogenic foci in children with infantile spasms. Methods : Fourteen children with infantile spasms (11 boys, 3 girls; mean age, $2.2{\pm}1.3$ years) were examined. When a cluster of spasms was detected during video electroencephalography (EEG) monitoring, $^{99m}Tc$ ethyl cysteinate dimer was slowly and continuously injected for 2 minutes to determine the presence of ictal SPECT. For 7 children, the ictal and interictal SPECT images were visually analyzed, while for the remaining 7 children, the SPECT images were analyzed using the subtraction ictal SPECT coregistered to magnetic resonance imaging (MRI) (SISCOM) technique. Subsequently, we analyzed the association between the ictal SPECT findings and those of other diagnostic modalities such as EEG, MRI, and positron emission tomography (PET). Results : Increase in cerebral blood flow on ictal SPECT involved the epileptogenic foci in 10 cases6 cases analyzed by visual assessment and 4 analyzed by the SISCOM technique. The ictal SPECT and video-EEG findings showed moderate agreement (Kappa=0.57; 95% confidence interval, 0.18-0.96). Conclusion : Ictal SPECT with prolonged injection of a tracer could provide supplementary information to localize the epileptogenic foci in infantile spasms.

Reduced Regional Cerebral Blood Flow in Patients with Traumatic Brain Injury Who Had No Structural Abnormalities on Magnetic Resonance Imaging : A Quantitative Evaluation of Tc-99m-ECD SPECT Findings (정상 MRI 소견을 보이는 외상성 뇌손상 환자에서 국소뇌혈류량의 이상)

  • Kim, Nam-Hee;Chung, Young-Ki
    • Korean Journal of Biological Psychiatry
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    • v.9 no.2
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    • pp.152-158
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    • 2002
  • Background & Purpose:Neuropsychological disorders after traumatic brain injury(TBI) are poorly correlated with structural lesions detected by structural neuroimaging techniques such as computed tomography(CT) scan or magnetic resonance imaging(MRI). It is well known that patients with TBI have cognitive and behavioral disorders even in the absence of structural lesions of the brain. This study investigated whether there are abnormalities of regional cerebral blood flow(rCBF) in TBI patients without structural abnormality on MRI, using technetium 99m ethyl cysteinate dimer(Tc-99m-ECD) single photon emission computed tomography(SPECT) scans. Materials and Methods:Twenty-eight TBI patients without structural abnormality on MRI(mild, n=13/moderate, n=9/severe, n=6) and fifteen normal controls were scanned by SPECT. A voxel-based analysis using statistical parametric mapping(SPM) was performed to compare the patients with the normal controls. Results:rCBF was reduced in the right uncus and the right lateral orbitofrontal gyrus in the TBI patients. However, no increase of rCBF was noted in the patients in comparison to the normal controls. Conclusions:These results suggest that the TBI patients, even in the absence of structural lesion of the brain, may have dysfunction of the brain, particularly of the orbitofrontal and anterior pole of the temporal cortex. They also suggest that SPECT can be a useful method to identify brain dysfunctions in combination with structural brain imaging and neuropsychological tests.

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Study on Friction Welding of SUS431 and SCM21 for External Shaft of Ship (선외기 샤프트용 재료의 마찰용접에 관한 연구)

  • 오세규;이종환;배명주;오명석
    • Journal of Advanced Marine Engineering and Technology
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    • v.17 no.4
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    • pp.38-48
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    • 1993
  • A study on friction welding of stainless steel bar(SUS431) to chrome molybdenum steel bar(SCM21) was accomplished experimentally through analysis for relations among friction welding conditions, tension test, hardness test, microstructure test and acoustic emission test. The results obtained are summarized as follows ; 1. Through friction welding of SUS431 bar to SCM21 bar, the optimum welding condition by considering on strength and toughness was found to be the range of heating time of 3-5 sec when the number of rotating speed of 2000rpm, heating pressure of 10kg/$mm^2$, and upsetting time of 4 sec. 2. Quantitative ralationship was identified between heating time($T_1$, sec) and tensile strength (${\sigma},\;kgf/mm^2$) of the friction welded joint and the relation equation is $\sigma$=52.62$T_1{^{0.06}}$. 3. Through AE test, quantitative relationship was confirmed between heating time($T_1$, sec) and total AE(N, counts) during welding, and the relation is computed as follows ; N=30413.6$e^{0.06T1}$. 4. It was confirmed that the quantitative ralationship exists between the tensile strength of the welded joints and AE cumulative counts. And the relation is computed as the following ; ${\sigma}$=16.37(ln N)- 116.4. 5. When ONZ=36500-41500 counts by $OT_1Z$=3~5sec, it was identified by experiment that the range of welded joint tensile strength is 55.6-57.7kgf/$mm^2$/ whose joint efficiency is more than 100%, and it was experimentally confirmed that the real-time nondestructive quality(strength) evaluation for the friction welded joints could be possible by acoustic emission technique.

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Comparison of Image Uniformity with Photon Counting and Conventional Scintillation Single-Photon Emission Computed Tomography System: A Monte Carlo Simulation Study

  • Kim, Ho Chul;Kim, Hee-Joung;Kim, Kyuseok;Lee, Min-Hee;Lee, Youngjin
    • Nuclear Engineering and Technology
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    • v.49 no.4
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    • pp.776-780
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    • 2017
  • To avoid imaging artifacts and interpretation mistakes, an improvement of the uniformity in gamma camera systems is a very important point. We can expect excellent uniformity using cadmium zinc telluride (CZT) photon counting detector (PCD) because of the direct conversion of the gamma rays energy into electrons. In addition, the uniformity performance such as integral uniformity (IU), differential uniformity (DU), scatter fraction (SF), and contrast-to-noise ratio (CNR) varies according to the energy window setting. In this study, we compared a PCD and conventional scintillation detector with respect to the energy windows (5%, 10%, 15%, and 20%) using a $^{99m}Tc$ gamma source with a Geant4 Application for Tomography Emission simulation tool. The gamma camera systems used in this work are a CZT PCD and NaI(Tl) conventional scintillation detector with a 1-mm thickness. According to the results, although the IU and DU results were improved with the energy window, the SF and CNR results deteriorated with the energy window. In particular, the uniformity for the PCD was higher than that of the conventional scintillation detector in all cases. In conclusion, our results demonstrated that the uniformity of the CZT PCD was higher than that of the conventional scintillation detector.

Study on Real-Time Weld Quality Evaluation by Acoustic Emission for Production of Drills by Friction Weldiing (마찰용접에 의한 드릴 생산에서의 AE에 의한 실시간 품질평가에 관한 연구)

  • 오세규;윤인진;오정환;오명석
    • Journal of Ocean Engineering and Technology
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    • v.7 no.2
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    • pp.121-130
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    • 1993
  • A study off riction welding of high speed steel(SKH 51) bar for blade side to carbon steel(STC 3)bar for shank side was carried out experimentally through tensile test, hardness test, microstructure, and acoustic emission (AE) test. So, this paper deals with optimizing the welding conditions and the real-time quality (strength) evaluation of friction weleded joints by acoustic emission technique. The results obtained are summarized as follows: (1) For friction welded joints of SKH 51to STC 3 steel bars, the total upset (U) increases linearly with an increase of heating time (t sub(1)). (2) The determined optimum welding conditions are heating time (t sub(1)) 7-9 sec, upsetting time (t sub(2)) 5 sec, heating pressure(P sub(1)) 12 kg sub(f)mm supper(2), upsetting pressure (P sub(2)) 15 kg sub(f) mm supper(2) and rotating speed (n) 2, 000 rpm, resulting in a computed relationship between the tensile strength of the joint .sigma. (kg sub(f) mm supper(2)) and the heating time t sub(1) (sec) as the following. sigma.=2.39t sub(1)

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Does High-Speed Rail Have Superiority over Motorway in Terms of CO2 Emission? (고속철도는 고속도로에 비하여 저탄소 친환경적인가?)

  • Kang, Taeseok;Chang, Hyunho
    • International Journal of Highway Engineering
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    • v.18 no.5
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    • pp.83-93
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    • 2016
  • PURPOSES : The aim of this article is to compare and identify eco-friendly competitiveness between (regional) motorway and high-speed rail(HSR) from the perspective of $CO_2$ emission in the Republic of Korea. METHODS : In order for an analysis of low-carbon competitiveness between the two modes, $CO_2e$ emission, $CO_2eppk$ (equivalent $CO_2$ gram per passenger kilometer), is employed as a comparison index. As for HSR, the index is calculated based on the passenger transport data and the gross of $CO_2e$ produced by Kyungbu high-speed line in 2013. Additionally, the gross of $CO_2e$ is computed by the greenhouse gas emission factors of domestic electricity generation mix. Regarding the index of motorway, it is directly calculated using both the official $CO_2e$ emission factor and the passenger-car occupancy of motorway. RESULTS : The results revealed, in the case of inter-regional transport, that the $CO_2e$ emission of displacement-based cars is 54.9% less than that of HSR, as the domestic electric power systems heavily relies on the thermal power plants over 66%. Note that internal combustion engines commonly used for vehicles are more energy-efficient than steam-driven turbines usually utilized for thermal power generation. CONCLUSIONS : It can be seen, at the very least in our study, that HSR has no superiority over motorway in the case of $CO_2e$ emission under the situations of domestic electricity generation mix. In addition, advanced eco-friendly vehicles have strong advantages over HSR. Therefore, all-out efforts should be made to develop and harvest renewable energy sources in order to achieve low-carbon HSR, sparing fossil fuels.

Importance of 3-dimensional imaging in the early diagnosis of chondroblastic osteosarcoma

  • Laura Althea Cuschieri;Rebecca Schembri-Higgans;Nicholas Bezzina;Alexandra Betts;Arthur Rodriguez Gonzalez Cortes
    • Imaging Science in Dentistry
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    • v.53 no.3
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    • pp.247-256
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    • 2023
  • The aim of this report is to present a case of chondroblastic osteosarcoma located in the right maxillary premolar region of a 17-year-old female patient. The initial clinical presentation and 2-dimensional (2D) radiographic methods proved inadequate for a definitive diagnosis. However, a cone-beam computed tomography scan revealed a hyperdense, heterogeneous lesion in the right maxillary premolar region, exhibiting a characteristic "sun-ray" appearance. To assess soft tissue involvement, a medical computed tomography scan was subsequently conducted. A positron emission tomography scan detected no metastasis or indications of secondary tumors. T1- and T2-weighted magnetic resonance imaging showed signal heterogeneity within the lesion, including areas of low signal intensity at the periphery. Histological examination conducted after an incisional biopsy confirmed the diagnosis of highgrade chondroblastic osteosarcoma. The patient was then referred to an oncology department for chemotherapy before surgery. In conclusion, these findings suggest that early diagnosis using 3-dimensional imaging can detect chondroblastic osteosarcoma in its early stages, such as before metastasis occurs, thereby improving the patient's prognosis.

Incidental Abnormal FDG Uptake in the Prostate on 18-fluoro-2-Deoxyglucose Positron Emission Tomography-Computed Tomography Scans

  • Kang, Pil Moon;Seo, Won Ik;Lee, Sun Seong;Bae, Sang Kyun;Kwak, Ho Sup;Min, Kweonsik;Kim, Wansuk;Kang, Dong Il
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.20
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    • pp.8699-8703
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    • 2014
  • 18-fluoro-2-deoxyglucose positron emission tomography-computed tomography ($^{18}F$-FDG PET/CT) scans are commonly used for the staging and restaging of various malignancies, such as head and neck, breast, colorectal and gynecological cancers. However, the value of FDG PET/CT for detecting prostate cancer is unknown. The aim of this study was to evaluate the clinical value of incidental prostate $^{18}F$-FDG uptake on PET/CT scans. We reviewed $^{18}F$-FDG PET/CT scan reports from September 2009 to September 2013, and selected cases that reported focal/diffuse FDG uptake in the prostate. We analyzed the correlation between $^{18}F$-FDG PET/CT scan findings and data collected during evaluations such as serum prostate-specific antigen (PSA) levels, digital rectal examination (DRE), transrectal ultrasound (TRUS), and/or biopsy to confirm prostate cancer. Of a total of 18,393 cases, 106 (0.6%) exhibited abnormal hypermetabolism in the prostate. Additional evaluations were performed in 66 patients. Serum PSA levels were not significantly correlated with maximum standardized uptake values (SUVmax) in all patients (rho 0.483, p=0.132). Prostate biopsies were performed in 15 patients, and prostate cancer was confirmed in 11. The median serum PSA level was 4.8 (0.55-7.06) ng/mL and 127.4 (1.06-495) ng/mL in the benign and prostate cancer groups, respectively. The median SUVmax was higher in the prostate cancer group (mean 10.1, range 3.8-24.5) than in the benign group (mean 4.3, range 3.1-8.8), but the difference was not statistically significant (p=0.078). There was no significant correlation between SUVmax and serum PSA, prostatic volume, or Gleason score. $^{18}F$-FDG PET/CT scans did not reliably differentiate malignant or benign from abnormal uptake lesions in the prostate, and routine prostate biopsy was not usually recommended in patients with abnormal FDG uptake. Nevertheless, patients with incidental prostate uptake on $^{18}F$-FDG PET/CT scans should not be ignored and should be undergo further clinical evaluations, such as PSA and DRE.

Evaluation and Comparison of Contrast to Noise Ratio and Signal to Noise Ratio According to Change of Reconstruction on Breast PET/CT (Breast PET CT 영상 재구성 변화에 따른 대조도 대 잡음비와 신호 대 잡음비의 비교평가)

  • Lee, Jea-Young;Lee, Eul-Kyu;Kim, Ki-Won;Jeong, Hoi-Woun;Lyu, Kwang-Yeul;Park, Hoon-Hee;Son, Jin-Hyun;Min, Jung-Whan
    • Journal of radiological science and technology
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    • v.40 no.1
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    • pp.79-85
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    • 2017
  • The purpose of this study was to measure contrast to noise ratio (CNR) and signal to noise ratio (SNR) according to change of reconstruction from region of interest (ROI) in breast positron emission tomography-computed tomography (PET-CT), and to analyze the CNR and SNR statically. We examined images of breast PET-CT of 100 patients in a University-affiliated hospital, Seoul, Korea. Each patient's image of breast PET-CT were calculated by using ImageJ. Differences of CNR and SNR among four reconstruction algorithms were tested by SPSS Statistics21 ANOVA test for there was statistical significance (p<0.05). We have analysis socio-demographical variables, CNR and SNR according to reconstruction images, 95% confidence according to CNR and SNR of reconstruction and difference in a mean of CNR and SNR. SNR results, with the quality of distributions in the order of PSF_TOF, Iterative and Iterative-TOF, FBP-TOF. CNR, with the quality of distributions in the order of PSF_TOF, Iterative and Iterative-TOF, FBP-TOF. CNR and SNR of PET-CT reconstruction methods of the breast would be useful to evaluate breast diseases.