• Title/Summary/Keyword: emerging

Search Result 5,736, Processing Time 0.035 seconds

A Comparative Study on the Effective Surface Resistance of High-$T_c$ Superconductor Films as Measured by Using the S-parameter Circle-fit and the Lorentzian-fit Methods (S-parameter Circle-fit과 Lorentzian-fit 방법으로 측정된 고온초전도체 박막의 유효표면저항 비교)

  • Kim, Min-Jeong;Jung, Ho-Sang;Lee, J.H.;Lee, Sang-Young
    • Progress in Superconductivity
    • /
    • v.9 no.2
    • /
    • pp.146-151
    • /
    • 2008
  • Measurements of surface resistance ($R_s$) of high temperature superconductor (HTS) films with accuracy are essential for microwave applications of HTS materials. In using the dielectric resonator method, uncertainties in the unloaded quality factor of the resonator cause significant errors in the measured $R_s$ of HTS films. We compare the Rs values of $YBa_2Cu_3O_{7-{\delta}}$ films calculated from the $Q_0$ as determined from the Lorentzian fit with that from the $Q_0$ as determined from the S-parameter circle-fit at temperatures between 15 K and 77 K. The two sets of values appeared to differ by 5%, 7%, 6%, and 11% at temperatures of 15, 60, 70, and 77 K, respectively, from each other, implying that careful error analysis needs to be performed in obtaining the $R_s$ of HTS films by using the Lorentzian-fit method, with the ones determined from the S-parameter circle-fit used as the reference.

  • PDF

Protein Disorder/Order Region Classification Using EPs-TFP Mining Method (EPs-TFP 마이닝 기법을 이용한 단백질 Disorder/Order 지역 분류)

  • Lee, Heon Gyu;Shin, Yong Ho
    • Journal of Korea Society of Industrial Information Systems
    • /
    • v.17 no.6
    • /
    • pp.59-72
    • /
    • 2012
  • Since a protein displays its specific functions when disorder region of protein sequence transits to order region with provoking a biological reaction, the separation of disorder region and order region from the sequence data is urgently necessary for predicting three dimensional structure and characteristics of the protein. To classify the disorder and order region efficiently, this paper proposes a classification/prediction method using sequence data while acquiring a non-biased result on a specific characteristics of protein and improving the classification speed. The emerging patterns based EPs-TFP methods utilizes only the essential emerging pattern in which the redundant emerging patterns are removed. This classification method finds the sequence patterns of disorder region, such sequence patterns are frequently shown in disorder region but relatively not frequently in the order region. We expand P-tree and T-tree conceptualized TFP method into a classification/prediction method in order to improve the performance of the proposed algorithm. We used Disprot 4.9 and CASP 7 data to evaluate EPs-TFP technique, the results of order/disorder classification show sensitivity 73.6, specificity 69.51 and accuracy 74.2.

Quantitative Analysis of Gartner's "Hype Cycle for Emerging Technologies" (가트너 "부상하는 기술을 위한 Hype Cycle"의 정량적 분석)

  • Park, Yoo-hyun
    • Journal of the Korea Institute of Information and Communication Engineering
    • /
    • v.22 no.8
    • /
    • pp.1041-1048
    • /
    • 2018
  • Gartner's Hype Cycle model is widely used to describe technology maturity, acceptability, and commercialization. In the Hype Cycle model, the techniques go through five stages, those are Innovation Trigger(first stage), stage Peak of Inflated Expectations(second stage), Trough of Disillusionment(third stage), Slope of Enlightenment(fourth stage) and Plateau of Productivity(fifth stage). In many studies, Hype Cycle is widely used as a basis for future prediction of technology, but the verification is somewhat lacking. In this paper, we analyzed the technologies that appeared in the Hype Cycle for the emerging technologies from 1995 to 2017. Through this, we found technologies that appeared as non first stage when first appearing, and techniques that showed a reversal of the maturity stage. In addition, we found that none of the technologies from 1995 to 2017 had gone through stages 1-5.

Systems Biology and Emerging Technologies Will Catalyze the Transition from Reactive Medicine to Predictive, Personalized, Preventive and Participatory (P4) Medicine

  • Galas, David J.;Hood, Leroy
    • Interdisciplinary Bio Central
    • /
    • v.1 no.2
    • /
    • pp.6.1-6.4
    • /
    • 2009
  • We stand at the brink of a fundamental change in how medicine will be practiced. Over the next 5-20 years medicine will move from being largely reactive to being predictive, personalized, preventive and participatory (P4). Technology and new scientific strategies have always been the drivers of revolutions and this is certainly the case for P4 medicine, where a systems approach to disease, new and emerging technologies and powerful computational tools will open new windows for the investigation of disease. Systems approaches are driving the emergence of fascinating new technologies that will permit billions of measurements on each individual patient. The challenge for health information technology will be how to reduce this enormous amount of data to simple hypotheses about health and disease. We predict that emerging technologies, together with the systems approaches to diagnosis, therapy and prevention will lead to a down turn in the escalating costs of healthcare. In time we will be able to export P4 medicine to the developing world and it will become the foundation of global medicine. The "democratization" of healthcare will come from P4 medicine. Its first real emergence will require the unprecedented integration of biology, medicine, technology and computation. as well as societal issues of major importance: ethical, regulatory, public policy, economic, and others. In order to effectively move the P4 scientific agenda forward new strategic partnerships are now being created with the large-scale integration of complementary skills, technologies, computational tools, patient records and samples and analysis of societal issues. It is evident that the business plans of every sector of the healthcare industry will need to be entirely transformed over the next 10 years.and the extent to which this will be done by existing companies as opposed to newly created companies is a fascinating question.

HCBP6 upregulates human SREBP1c expression by binding to C/EBPβ-binding site in the SREBP1c promoter

  • Yang, Xueliang;Han, Ming;Liu, Shunai;Yuan, Xiaoxue;Liu, Xiaojing;Feng, Shenghu;Zhou, Li;Li, Yaru;Lu, Hongping;Cheng, Jun;Lin, Shumei
    • BMB Reports
    • /
    • v.51 no.1
    • /
    • pp.33-38
    • /
    • 2018
  • Sterol regulatory element-binding protein-1c (SREBP1c) plays an important role in triglyceride (TG) homeostasis. Although our previous study showed that hepatitis C virus core-binding protein 6 (HCBP6) regulates SREBP1c expression to maintain intracellular TG homeostasis, the mechanism underlying this regulation is unclear. In the present study, we found that HCBP6 increased intracellular TG levels by upregulating SREBP1c expression. HCBP6 increased SREBP1c transcription by directly binding to the SREBP1c promoter (at the -139- to +359-bp region). Moreover, we observed that HCBP6 interacted with $C/EBP{\beta}-binding$ site in the SREBP1c promoter both in vitro and in vivo. These results indicate that HCBP6 upregulates human SREBP1c expression by binding to the $C/EBP{\beta}-binding$ site in the SREBP1c promoter.

Development of a Risk Assessment Tool for Emerging Infectious Diseases (신종감염병의 양적 및 질적 혼합 위험 평가 모델 개발)

  • Woo, Darae;Choi, Eunmi;Choe, Young June;Yeh, Jungyong;Park, Sangshin
    • Health Policy and Management
    • /
    • v.32 no.4
    • /
    • pp.356-367
    • /
    • 2022
  • Background: The emergence of new infectious diseases threatens public health, increasing socioeconomic damage, and national risks. This study aimed to develop an evidence-based risk assessment tool to quickly respond to new infectious diseases. Methods: The risk elements were extracted by reviewing the risk assessment methods of the World Health Organization, United States, Europe, United Kingdom, and Germany, and the validity and priority of elements were determined through expert meetings and Delphi surveys. Then, the scale and level for each risk element were defined and a final score calculation method according to the risk evaluation result was derived. The developed risk assessment tool was verified using data at the time of domestic transmission of an emerging infectious disease. Results: In case of spread of actual infectious diseases, priority is determined based on the criticality of the elements in each area of transmissibility and severity, from which the weighted score of the risk assessment is derived. Then, the risk score for each element was calculated by multiplying the average value of the risk evaluation by its weight and the evaluation risk assessment score for the two areas was calculated. At last, the final score is plotted in a matrix where the x-axis indicates the transmissibility and the y-axis the severity and plotted on the coordinate plane for time series use. Conclusion: With respect to transmissibility and severity, this risk assessment method to respond to new and re-emerging infectious diseases enables rapid and evidence-based evaluation by quantitatively and qualitatively assessing various risk elements.

Recent Trends in Salmonella Outbreaks and Emerging Technology for Biocontrol of Salmonella Using Phages in Foods: A Review

  • Oh, Jun-Hyun;Park, Mi-Kyung
    • Journal of Microbiology and Biotechnology
    • /
    • v.27 no.12
    • /
    • pp.2075-2088
    • /
    • 2017
  • Salmonella is one of the principal causes of foodborne outbreaks. As traditional control methods have shown less efficacy against emerging Salmonella serotypes or antimicrobial-resistant Salmonella, new approaches have been attempted. The use of lytic phages for the biocontrol of Salmonella in the food industry has become an attractive method owing to the many advantages offered by the use of phages as biocontrol agents. Phages are natural alternatives to traditional antimicrobial agents; they have proven effective in the control of bacterial pathogens in the food industry, which has led to the development of different phage products. The treatment with specific phages in the food industry can prevent the decay of products and the spread of bacterial diseases, and ultimately promotes safe environments for animal and plant food production, processing, and handling. After an extensive investigation of the current literature, this review focuses predominantly on the efficacy of phages for the successful control of Salmonella spp. in foods. This review also addresses the current knowledge on the pathogenic characteristics of Salmonella, the prevalence of emerging Salmonella outbreaks, the isolation and characterization of Salmonella-specific phages, the effectiveness of Salmonella-specific phages as biocontrol agents, and the prospective use of Salmonella-specific phages in the food industry.

CEO Compensation and Unobserved Firm Performance in Pakistan

  • SHEIKH, Muhammad Fayyaz;BHUTTA, Aamir Inam;SULTAN, Jahanzaib
    • The Journal of Asian Finance, Economics and Business
    • /
    • v.6 no.3
    • /
    • pp.305-313
    • /
    • 2019
  • The study examines whether higher CEO compensation is related to unobserved future firm performance in an emerging market, Pakistan. Further, it extends its scope to analyzing the impact of group affiliation and ownership concentration on the relationship between CEO compensation and future firm performance. The study uses an unbalanced panel data consisting of 1508 firm-year observations from 225 non-financial listed companies in Pakistan Stock Exchange (PSX) for period 2005 to 2012. The multiple regression models adjusted to heteroskedasticity and autocorrelation in error terms are used. The study finds that, in general, CEO compensation is positively associated with future operating performance. However, higher CEO compensation leads to lower operating performance in firms that have lower ownership concentration and are affiliated with business groups. When firms are not affiliated with any group and have high ownership concentration, the relationship between excessive CEO compensation and future operating performance becomes insignificant. Given that efficient compensation packages may lead to long term value creation to shareholders and reduce agency problems, this study highlights an important moderating role of ownership concentration and group affiliation of the firms in emerging markets.

Apical membrane antigen-1 (AMA-1) gene sequences of re-emerging Plasmodium vivax in South Korea

  • Han, Eun-Taek;Park, Jae-Hwan;Shin, Eun-Hee;Choi, Min-Ho;Oh, Myoung-Don;Chai, Jong-Yil
    • Parasites, Hosts and Diseases
    • /
    • v.40 no.3
    • /
    • pp.157-162
    • /
    • 2002
  • Plasmodium vivax malaria re-emerged in South Korea in 1993, and epidemics continue since then. We examined genetic variation in the region encompassing the apical membrane antigen-1 (PvAMA-1) of the parasites by DNA sequencing of the 22 re-emerging p. vivax isolates. The genotype of the PvAMA-1, which was based on sequence data previously reported for the polymorphic regions, showed that two haplotypes were present at one polymorphic site. Compared with reported data, the two types, SKOR type I and type II, were similar to Chinese CH- l0A and CH-05A isolates, respectively. Thus, the present study showed that two genotypes of AMA-1 genes coexist in the re-emerging Korean P. vivax.

Sustainable Business Strategies for Local Fashion Communities (small and medium scale enterprises) in Ethiopia and Ukraine

  • Khurana, Karan;Ryabchykova, Kateryna
    • Fashion & Textile Research Journal
    • /
    • v.20 no.1
    • /
    • pp.22-33
    • /
    • 2018
  • The aim of the research study is to carve sustainable business strategies for the fashion communities in Ethiopia and Ukraine which are suffering today due to ever-increasing share of fast fashion consumerism. Fashion houses and international brands propagandize sustainability and consumption for better consumer base, where as originally sustainable local-based craftsmen still stay in the shade. Four communities/local designers are selected from the countries through the method of purposive sampling. Qualitative analysis is the basis of the research as we performed personal interviews and in-depth analysis of the communities to diagnose the problems and subsequently devise the solutions. In this research, we have studied and analyzed the problems faced by hereditary communities and ethnic designers in small and medium scale enterprise sector from two emerging economies. After the grounding the difficulties faced we advised strategies for sustainable future growth to the companies. The current academic literature on small and medium scale enterprises highlights the problems and solutions for general industry sectors. This paper brings attention to fashion communities and designers who promote national heritage and are struggling to survive in emerging economies due to industrialization and globalization. Moreover the comparison of the two geographies is unique in nature.