• Title/Summary/Keyword: effective diameter

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Synthesis of Hyaluronic Acid Microsphere Crosslinked with Polyethylene Glycol Diglycidyl Ether Prepared by A Simple Fluidic Device

  • Yuk, Sujeong;Jeong, Dayeon;Lee, Yongjun;Lee, Deuk Yong
    • Journal of Biomedical Engineering Research
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    • v.42 no.6
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    • pp.251-258
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    • 2021
  • Hyaluronic acid (HA) microspheres (MSs) crosslinked with polyethylene glycol diglycidyl ether (PEGDE) are prepared using a simple fluidic device (SFD) to investigate the optimized parameters. A solution mixture of PEGDE in 2-methyl-1-propanol was prepared as a continuous phase in SFD. HA solutions of 1 wt% concentration were introduced into SFD as a discontinuous phase. The HA solution prepared by stirring for more than 48 h exhibited spherical MSs at the needle tip inside the ring cap. As the flow rate of the continuous phase increased from 0.7 to 1.9 mL/min, the diameter of the MS decreased from 173±36 ㎛ to 129±13 ㎛. Although the PEGDE concentration in the range of 0.2 to 1.8 vol% did not affect the diameter of the MS, the microstructure of MS, consisting of inner hollow void and wall, was changed. The inner void and wall size decreased and increased from 79.5 ㎛ to 57.2 ㎛ and from 10.3 ㎛ to 21.4 ㎛, respectively, with increasing PEGDE concentration from 0.2 vol% to 1.8 vol%. FT-IR peaks located around 2867 cm-1 and 1088 cm-1 indicated that the HA MS prepared at different PEGDE concentrations were chemically crosslinked. The HA MSs containing different PEGDE concentrations exhibited quantitative cell viability of more than 98%. L-929 cells adhered well to the HA MSs and proliferated continuously with increasing culture time to 48 h regardless of PEGDE concentration, implying that the HA MSs are clinically safe and effective.

Surface Fracture Behaviors of Unidirectional and Cross Ply Glass Fiber/Epoxy Lamina-Coated Glass Plates under a Small-Diameter Steel Ball Impact (일방향 및 직교형 유리섬유/에폭시 복합재로 피막된 판유리의 미소강구 충격에 의한 표면파괴거동)

  • Chang, Jae-Young;Choi, Nak-Sam
    • Composites Research
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    • v.22 no.4
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    • pp.33-40
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    • 2009
  • Fiber orientation effects on the impact surface fracture of the glass plates coated with the glass fiber/epoxy lamina layer were investigated using a small-diameter steel-ball impact experiment. Four kinds of materials were used: soda-lime glass plates, unidirectional glass fiber/epoxy layer(one ply, two plies)-coated, crossed glass tiber/epoxy layer (two plies)-coated glass plates. The maximum stress and absorbed fracture energy were measured on the back surface of glass plates during the impact. With increasing impact velocity, various surface cracks such as ring, cone, radial and lateral cracks appeared near the impacted site of glass plates. Cracks in the plate drastically diminished by glass fiber coating. The tiber orientation guided the directions of delamination and plastic deformation zones between the tiber layer and the glass plate. Impact surface-fracture indices expressed in terms of the maximum stress and absorbed energy could be used as an effective evaluation parameter of the surface resistance.

Effect of Ambient Air Pollution on Years of Life Lost from Deaths due to Injury in Seoul, South Korea (대기오염물질이 손상으로 인한 손실수명연수에 미치는 영향: 서울특별시를 중심으로)

  • Sun-Woo Kang;Subin Jeong;Hyewon Lee
    • Journal of Environmental Health Sciences
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    • v.49 no.3
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    • pp.149-158
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    • 2023
  • Background: Injury is one of the major health problems in South Korea. Few studies have evaluated both intentional and unintentional injury when investigating the association between exposure to air pollutants and injury. Objectives: We aimed to explore the association between short-term exposure to ambient air pollution and years of life lost (YLLs) due to injury. Methods: Data on daily YLLs for 2002~2019 were obtained from the the Death Statistics Database of the Korean National Statistical Office. This study estimated short-term exposure to particulate matter with an aerodynamic diameter of <10 ㎛ (PM10), particulate matter with an aerodynamic diameter of <2.5 ㎛ (PM2.5), sulfur dioxide (SO2), nitrogen dioxide (NO2), carbon monoxide (CO), and ozone (O3). This time series study was conducted using a generalized additive model (GAM) assuming a Gaussian distribution. We also evaluated a delayed effect of ambient air pollution by constructing a lag structure up to seven days. The best-fitting lag was selected based on smallest generalized cross validation (GCV) value. To explore effect modification by intentionality of injury (i.e., intentional injury [self-harm, assault] and unintentional injury), we conducted stratified subgroup analyses. Additionally, we stratified unintentional injury by mechanism (traffic accident, fall, etc.). Results: During the study period, the average daily YLLs due to injury was 307.5 years. In the intentional injury, YLLs due to self-harm and assault showed positive association with air pollutants. In the unintentional injury, YLLs due to fall, electric current, fire and poisoning showed positive association with air pollutants, whereas YLLs due to traffic accident, mechanical force and drowning/submersion showed negative associations with air pollutants. Conclusions: Injury is recognized as preventable, and effective strategies to create a safe society are important. Therefore, we need to establish strategies to prevent injury and consider air pollutants in this regard.

Design of Roof Side Rail by Hot Blow Forming using High Strength Aluminum (핫블로우 포밍을 이용한 고강도 알루미늄 루프 사이드 레일 설계)

  • M. G. Kim;J. H. Lee;D. C. Ko
    • Transactions of Materials Processing
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    • v.32 no.6
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    • pp.311-320
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    • 2023
  • Recently, lightweight of automotive parts has been required to solve environmental problems caused by global warming. Accordingly, research and development are proceeded on manufacturing of parts using aluminum that can replace steel for lightweight of the automotive parts. In addition, high strength aluminum can be applied to body parts in order to meet both requirements of lightening and improving crash safety of vehicle. In this study, hot blow forming of roof side rail is employed to manufacturing of the automotive parts with high strength aluminum tube. In hot blow forming, longer forming times and excessive thinning can be occurred as compared with conventional manufacturing processes. So optimization of process conditions is required to prevent excessive thinning and to uniformize thickness distribution with fast forming time. Mechanical properties of high strength aluminum are obtained from tensile test at high temperature. These properties are used for finite element(FE) analysis to investigate the effect of strain rate on thinning and thickness distribution. Variation of thickness was firstly investigated from the result of FE analysis according to tube diameter, where the shapes at cross section of roof side rail are compared with allowable dimensional tolerance. Effective tube diameter is determined when fracture and wrinkle are not occurred during hot blow forming. Also FE analysis with various pressure-time profiles is performed to investigate the their effects on thinning and thickness distribution which is quantitatively verified with thinning factor. As a results, optimal process conditions can be determined for the manufacturing of roof side rail using high strength aluminum.

Retrospective study of implant stability according to the implant length, diameter and position (임플란트 길이, 직경 및 식립 위치에 따른 임플란트 안정성에 관한 후향적 연구)

  • Kim, Ji-Hye;Jeon, Jin-Yong;Heo, Yu-Ri;Son, Mee-Kyoung
    • The Journal of Korean Academy of Prosthodontics
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    • v.51 no.4
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    • pp.269-275
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    • 2013
  • Purpose: The aim of this retrospective study was to evaluate the influence of implant diameter, length and placement to implant stability. Materials and methods: Total 90 implants (US II plus$^{TM}$, Osstem co, Busan, Korea) of 72 patients were determined as experimental samples. The factors of diameters(${\phi}$ 4 mm, ${\phi}$ 5 mm), lengths (10 mm, 11.5 mm, 13 mm), and implant placement (maxilla, mandible) were analyzed. The stability of the implants was measured by resonance frequency analysis (RFA) at the time of implant placement and impression taking. The difference of ISQ values according to patient's gender was evaluated by Independent t-test. ISQ values were compared between implant diameter, length and placement using one-way ANOVA and Tukey HSD test (${\alpha}=.05$). To compare ISQ values between at the time of surgery and impression taking, paired t-tests were used (${\alpha}=.05$). Results: The change of implant length did not show significant different on the ISQ value (P>.05). However, 5 mm diameter implants had higher ISQ values than 4 mm diameter implants (P<.05). Implants placed on the mandible showed significantly higher ISQ values than on the maxilla (P<.05). Conclusion: In order to increase implant stability, it is better to select the wider implant, and implants placed on mandible are possible to get higher stability than maxilla. ISQ values at impression taking showed higher implant stability than ISQ values at implant placement, it means that RFA is clinically effective method to evaluate the change of implant stability through the osseointegration. The consideration of the factors which may affect to the implant stability will help to determine the time of load applying and increase the implant success rate.

Hydrodynamic Dispersion Characteristics of Multi-soil Layer from a Field Tracer Test and Laboratory Column Experiments (현장추적자시험과 실내주상실험을 이용한 복합토양층의 수리분산특성 연구)

  • Kang, Dong-Hwan;Yang, Sung-Il;Kim, Tae-Yeong;Kim, Sung-Soo;Chung, Sang-Yong
    • Journal of Soil and Groundwater Environment
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    • v.13 no.4
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    • pp.1-7
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    • 2008
  • This study analyzed for hydrodynamic dispersion characteristics of multi-soil layer (Silt and clay, Find sand, Coarse sand), data of a field tracer test on the multi-soil layer and data of laboratory column experiments on the samples on each soil layers. Through the analysis of permeability and flow, MS (Silt and clay) and FS (Fine sand), which were low effective porosity, were higher average linear velocity while CS (Coarse sand), which was high effective porosity, was higher hydraulic conductivity. Hydraulic conductivity function based on average soil particle diameter was assumed Y=$3.49{\times}10^{-8}e^{15320x}$ and coefficient of determination was 0.90. Average linear velocity function based on average soil particle diameter was assumed Y=$1.88{\times}10^{-7}e^{11459x}$ and coefficient of determination was 0.81. Longitudinal dispersivity function based on average soil particle diameter was Y = 0.00256$e^{5971x}$ and coefficient of determination was 0.98. According to the linear regression analysis of average linear velocity and longitudinal dispersivity, assumed function was Y = 21.7527x + 0.0063, and coefficient of determination was 0.9979. The ratio of field scale/laboratory scale was 54.09, it exhibited scale-dependent effect of hydrodynamic dispersion. Field longitudinal dispersivity (1.39m) was 7.47 times as higher than longitudinal dispersivity estimated by the methods of Xu and Eckstein (1995). Hydrodynamic dispersion on CS layer was occurred mainly by diffusion flow in the test aquifer.

Design for Installation of Suction Piles in Sand Deposits for Mooring of Floating Offshore Structures (부유식 해상구조물의 계류를 위한 사질토 지반의 석션파일 설계)

  • Park, Chul-Soo;Lee, Ju-Hyung;Baek, Du-Hyun;Do, Jin-Ung
    • Journal of the Korean Geotechnical Society
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    • v.30 no.10
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    • pp.33-44
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    • 2014
  • The preliminary design of suction pile as the supporting system for concrete floating structures was performed for the pilot project of the southwest coast area in Korea. Prior to starting design work, site conditions of the area including ground and hydraulic conditions, and a 100-year return period external force were throughly evaluated. The suction pile for mooring of the offshore floating structures has to satisfy the lateral resistance against external force as well as the penetration ability according to the soil conditions such as soil types, shear strengths, effective stresses, and seepage forces. In the design, the required penetration depths, which were stable for lateral resistance, were evaluated with the diameters of cylindrical suction pile as the final installing ones. And the design suction pressures at each penetrating depths, at which sand boiling did not occur, were assessed through the comparison of penetration and penetrationresistance forces. As a result, it was impossible for suction piles with the diameter range of 3.0~5.0 m to penetrate into required penetration depths. On the other hand, suction piles with the diameter range of 6.0 m and 7.0 m satisfied both the horizontal stability and the penetration ability by design suction pressures at the required penetration depths of 8.5 m and 8.0 m, respectively.

An Experimental Study on Mechanical Properties of Hybrid Fiber Reinforced Concrete Pavement (하이브리드 섬유로 보강된 콘크리트 포장의 역학적 특성 실험연구)

  • Park, Jong-Sup;Choi, Sung-Yong;Jung, Woo-Tai;Park, Young-Hwan
    • Journal of the Korea Concrete Institute
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    • v.25 no.1
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    • pp.11-18
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    • 2013
  • Cement concrete pavement offers long-term service life and excellent applicability for heavy traffic. It is easier to purchase and more durable and economical than the asphalt pavement. However, it is difficult to repair and rehabilitate compared to the asphalt pavement when it comes to the maintenance problem. Since the crack is the main reason of the damage of concrete pavement, it is necessary to control the early and long-term crack in the concrete pavement. In this experimental study, the basic performance tests have been carried out to investigate the effect of hybrid fibers which were composed of micro fibers with small diameter and high aspect ratio and macro fibers with large diameter and low aspect ratio on the concrete pavement, in which lower water ratio and larger aggregates were used compared to the general concrete mixture. The test results showed that the flexural strength and toughness of concrete pavement mixture have been increased with the use of hybrid fibers in the concrete pavement mixture, even though they were less effective compared to the normal concrete mixture. It was found that the hybrid fibers were effective to control the early shrinkage of the concrete pavement which is one of the main reasons of the damage in the concrete pavement.

Effects of Planting Date on Growth and Yield of Bitter Gourd (Mormordica charantia L.) in Rain Shielding Plastic House (여주 비가림 재배 시 정식시기가 생육 및 수량에 미치는 영향)

  • Kim, Young Suk;Kim, Geun Hye;Yoo, Mi Bok;Go, Hung Six;Kim, Tae Soo;Kim, Chun Hwan;Seong, Ki Cheol
    • Journal of Bio-Environment Control
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    • v.25 no.1
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    • pp.71-75
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    • 2016
  • The experiment was carried out to examine the effects of planting date on the growth and marketable yield of bitter gourd grown in rain-shield plastic houses. Bitter gourd cv 'Dragon' seedlings were separately transplanted during the months of June, July and August, 2015. The training method of all plants was made with four lateral vines and pinching the main vine. Lateral length of plants exhibited no significant difference between each planting date. However, bitter gourd planted in June had significantly higher main stem diameter than those treatments planted on August. The application of planting date was found effective in increasing marketable yield and number of fruits. June, as a planting date, had the highest marketable yield (6,439kg/10a), whereas bitter gourd planted in August had the lowest yield (870kg/10a) which were also consistent in terms of the number of fruits. Fruit length and diameter had no significant differences as affected by treatments. Therefore, planting date of bitter gourd in June was effective in increasing yield of fruit in rain-shield plastic house conditions.

Analysis of Hydrodynamic Similarity in Three-Phase Fluidized Bed Processes (삼상유동층 공정에서 수력학적 Similarity 해석)

  • Lim, Ho;Lim, Hyun-Oh;Jin, Hae-Ryoung;Lim, Dae-Ho;Kang, Yong
    • Korean Chemical Engineering Research
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    • v.49 no.6
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    • pp.790-797
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    • 2011
  • Hydrodynamic similarity was analyzed by employing scaling factor in three phase fluidized beds. The scaling factor was defined based on the holdups of gas, liquid and solid particles and effectivity volumetric flux of fluids between the two kinds of fluidized beds with different column diameter. The column diameter of one was 0.102 m and that of the other was 0.152 m. Filtered compressed air, tap water and glass bead of which density was 2,500 kg/$m^3$ were used as gas, liquid and solid phases, respectively. The individual phase holdups in three phase fluidized beds were determined by means of static pressure drop method. Effects of gas and liquid velocities and particle size on the scaling factors based on the holdups of each phase and effective volumetric flux of fluids were examined. The deviation of gas holdup between the two kinds of three phase fluidized beds decreased with increasing gas or liquid velocity but increased with increasing fluidized particle size. The deviation of liquid holdup between the two fluidized beds decreased with increasing gas or liquid velocity or size of fluidized solid particles. The deviation of solid holdup between the two fluidized beds increased with increasing gas velocity or particle size, however, decreased with increasing liquid velocity. The deviation of effective volumetric flux of fluids between the two fluidized beds decreased with increasing gas velocity or particle size, but increased with increasing liquid velocity. The scaling factor, which was defined in this study, could be effectively used to analyze the hydrodynamic similarity in three phase fluidized processes.