• Korean Journal of Materials Research
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• v.20 no.3
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• pp.132-136
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• 2010

This study examined the biostability and drug delivery efficiency of g-$Fe_2O_3$ magnetic nanoparticles (GMNs) by cytotoxicity tests using various tumor cell lines and normal cell lines. The GMNs, approximately 20 nm in diameter, were prepared using a chemical coprecipitation technique, and coated with two surfactants to obtain a water-based product. The particle size of the GMNs loaded on hangamdan drugs (HGMNs) measured 20-50 nm in diameter. The characteristics of the particles were examined by X-ray diffraction (XRD), field emission scanning electron microscopy (FE-TEM) and Raman spectrometer. The Raman spectrum of the GMNs showed three broad bands at 274, 612 and $771\;cm^1$. A 3-(4, 5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide (MTT) assay showed that the GMNs were non-toxic against human brain cancer cells (SH-SY5Y, T98), human cervical cancer cells (Hela, Siha), human liver cancer cells (HepG2), breast cancer cells (MCF-7), colon cancer cells (CaCO2), human neural stem cells (F3), adult mencenchymal stem cells (B10), human kidney stem cells (HEK293 cell), human prostate cancer (Du 145, PC3) and normal human fibroblasts (HS 68) tested. However, HGMNs were cytotoxic at 69.99% against the DU145 prostate cancer cell, and at 34.37% in the Hela cell. These results indicate that the GMNs were biostable and the HGMNs served as effective drug delivery vehicles.

• Journal of Korean Ophthalmic Optics Society
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• v.14 no.3
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• pp.29-35
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• 2009

Purpose: To develop a relay lens type scope with 70 mm eye relief. Methods: By using Sigma 2000 design program, we designed and manufactured a relay lens type scope with 70 mm eye relief, which is integrated after designing an objective part with relay lenses and an eyepiece part, respectively. Results: The characteristics of the relay lens type scope with 70 mm eye relief whch is designed and manufactured by methods, which integrate after respectively designing an object part with relay lenses and an eyepiece part, have the magnification of $+4{\times}$,the length from 1st lens to last lens of about 105 mm, the barrel diameter of 18mm, and the effective diameter of 13 mm. Also we know that the resolution line width is 275 cycles/rad at the 30% MTF value criterion. Conclusions: We could design and manufacture the relay type scope with 70 mm eye relief, the characteristics of which have the magnification of $+4.0{\times}$the MTF above 30% at 275 cycles/rad, and the length from 1st lens to last lens of about 105 mm.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.37 no.1
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• pp.77-82
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• 2013

A cyclone separator has been widely used in various industrial processes for removing fine particulate matter because it is easy to fabricate, cost effective, and adaptable to extremely harsh conditions. However, owing to the complex flow field in cyclones, a complete understanding of the detailed mechanisms of particulate removal has not yet been gained. In this study, a theoretical analysis was performed for calculating the collection efficiency and cut-off size in cyclones by taking into account the effects of geometrical and flow parameters. The collection efficiency and cut-off size values predicted by the theoretical model showed good agreement with experimental measurements for particles with a diameter of $0.5-30{\mu}m$. It was also revealed that the surface friction, along with the flow and geometrical parameters, has a significant effect on the cyclone performance.

• Journal of the Korean Society of Fisheries and Ocean Technology
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• v.53 no.3
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• pp.276-285
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• 2017

The research vessel NARA equipped with an azimuth thruster system was built in 2015. There are few vessels with this propulsion system in Korea. This vessel has two modes such as the normal for maneuvering and the power for investigation, and the other two modes as one axis and two axes on the operating. This type of vessels does not seem to have a clear grasp of the maneuvering character in comparison with the vessel with a conventional propulsion system. So the authors carried out the sea test for the turning, the zigzag and the inclination, and the results are as follows. In turning test, the case of using the two axes mode is much better than the case of using the one axis mode for the elements of turning, such as advance, transfer, tactical diameter and final diameter, but turning hard over the rudder in full speed is very vulnerable to capsize in both modes. In zigzag test, the yaw quicking responsibility index, T is very large excessively, which means a bad counter maneuvering ability, so an operator has to keep in mind that in turning operation. If necessary to avoid collision at head on situation, it may be a more effective method to use the crash astern stop than the turning according to the conditions and circumstances for the shortest stopping distance is very short.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.38 no.4
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• pp.177-183
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• 2015

Incremental sheet metal forming is a manufacturing process to produce thin parts using sheet metals by a series of small incremental deformation. The process rarely needs dedicated dies and molds, thus, preparation time for the process is relatively short as to be compared to conventional metal forming. Spring back in sheet metal working is very common, which causes critical errors in dimensions. Incremental sheet metal forming is not fully investigated yet. Hence, incremental sheet metal forming frequently produces inaccurate parts. This paper proposes a method to minimize dimensional errors to improve shape accuracy of products manufactured by incremental forming. This study conducts experiments using an exclusive incremental forming machine and the material for these experiments are sheets of aluminum AL1015. This research defines a process parameter and selects a few factors for the experiments. The parameters employed in this paper are tool feed rate, tool diameter, step depth, material thickness, forming method, dies applied, and tool path method. In addition, their levels for each factor are determined. The plan of the experiments is designed using orthogonal array $L_8$ ($2^7$) which requires minimum number of experiments. Based on the measurements, dimensional errors are collected both on the tool contacted surfaces and on the non-contacted surfaces. The distances between the formed surfaces and the CAD models are scanned and recorded using a commercial software product. These collected data are statistically analyzed and ANOVAs (analysis of variances) are drawn up. From the ANOVAs, this paper concludes that the process parameters of tool diameter, forming depth, and forming method are the significant factors to reduce the errors on the tool contacted surface. On the other hand, the experimental factors of forming method and dies applied are the significant factors on the non-contacted surface. However, the negative forming method always produces better accuracy than the positive forming method.

• Nuclear Engineering and Technology
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• v.52 no.5
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• pp.925-936
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• 2020

To ascertain the characteristics of pool sloshing behavior that might be encountered during a core disruptive accident of sodium-cooled fast reactors, in our earlier work several series of experiments were conducted under various scenarios including the condition with mono-sized solid particles. It is found that under the particle-bed condition, three typical flow regimes (namely the bubble-impulsion dominant regime, the transitional regime and the bed-inertia dominant regime) could be identified and a flow-regime model (base model) has been even successfully established to estimate the regime transition. In this study, aimed to further understand this behavior at more realistic particle-bed conditions, a series of simulated experiments is newly carried out using mixed-size particles. Through analyses, it is verified that for present scenario, by applying the area mean diameter, our previously-developed base model can provide the most appropriate predictive results among the various effective diameters. To predict the regime transition with a form of extension scheme, a correction factor which is based on the volume-mean diameter and the degree of convergence in particle-size distribution is suggested and validated. The conducted analyses in this work also indicate that under certain conditions, the potential separation between different particle components might exist during the sloshing process.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.46 no.11
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• pp.944-951
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• 2018

Artificial icing test and wind tunnel test can be performed to reduce the development period when a rotorcraft is required operation under icing situations. Artificial icing test of the KUH(Korean Utility Helicopter) was performed in advance to verify anti-icing and de-icing performance before natural icing test. Although high-precision sensor, the CCP(Cloud Combination Probe) is used to measure icing test condition parameters such as LWC(Liquid Water Content) and MVD(Median Volume Diameter), the measured values need to be verified in various methods due to the possibility of uncertainties which are the test atmosphere environment, sensor errors, and etc. The calculated LWC from the ice thickness cumulated on the fuselage of the KUH is compared to the measured value by CCP, and the results show the effective indirect method to check the test conditions.

• Journal of Pharmacopuncture
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• v.23 no.4
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• pp.247-251
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• 2020

Objectives: Ganglion cysts require a sustainable treatment that suppresses their frequent recurrence. This study aimed to explore the clinical effects of Scolopendra pharmacopuncture (SP) and electroacupuncture on ganglion cysts. Methods: We retrospectively reviewed the patient records and follow-up reports for 20 patients with wrist ganglion cysts who received SP and electroacupuncture from April 2016 to March 2017. The cyst diameter, recurrence, visual analog scale (VAS) scores for pain, the Korean version of the disabilities of arm, shoulder, and hand (K-DASH) score, and the Korean version of the patient-rated wrist evaluation (K-PRWE) score before and after treatment were noted. Results: After treatment, the cyst diameter decreased significantly from 13.61 ± 6.41 mm to 5.15 ± 6.18 mm (p < 0.001), and VAS score for pain decreased from 1.31 ± 1.77 to 0.41 ± 0.33 (p = 0.021). Further, the K-DASH score decreased significantly from 8.97 ± 12.66 to 2.21 ± 7.39 (p = 0.016), and score for the function subscale of K-PRWE decreased from 11.37 ± 4.48 to 9.1 ± 3.67 (p = 0.046). No recurrences were reported from the followed-up patients. Any complication related to SP or electroacupuncture was not observed, except mild rash, itching, and swelling at the injection site in four patients. Conclusion: Combination of SP and electroacupuncture may be effective in treating ganglion cysts; further prospective studies with large population are needed to clarify the effect of SP and electroacupuncture.

• Geomechanics and Engineering
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• v.29 no.2
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• pp.183-192
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• 2022

Piled raft foundations are widely used and effective in supporting high-rise buildings around the world. In this study, a piled raft system was numerically simulated using PLAXIS 3D. The settlement comparison results between the actual building measurements and the three-dimensional (3D) numerical analysis, were in good agreement, indicating the usefulness of this approach for the evaluation of the feasibility of using a piled raft foundation in Ho Chi Minh City subsoil. The effects were investigated of the number of piles based on pile spacing, pile length, raft embedment on the settlement, load sharing, bending moments, and the shear force of the piled raft foundation in Ho Chi Minh City subsoil. The results indicated that with an increased number of piles, increased pile length, and embedding raft depth, the total and differential settlement decreased. The optimal design consisted of pile numbers of 60-70, corresponding to pile spacings is 5.5-6 times the pile diameter (D_p), in conjunction with a pile length-to-pile diameter ratio of 30. Furthermore, load sharing by the raft, by locating it in the second layer of stiff clay, could achieve 66% of the building load. The proposed model of piled raft foundations could reduce the total foundation cost by 49.61% compared to the conventional design. This research can assist practicing engineers in selecting pile and raft parameters in the design of piled raft foundations to produce an economical design for high-rise buildings in Ho Chi Minh City, Viet Nam, and around the world.

• Journal of the Korean Wood Science and Technology
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• v.30 no.4
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• pp.58-65
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• 2002

This research was carried out to develop field treatment techniques of thinned small diameter softwood logs and less utilized hardwood logs using sap displacement method. In this paper, we report the feasibility of using transpiration method and butt-end method for the treatment of three softwood species and three hardwood species with preservatives, fire-retardant chemicals, and dimensional stabilizer. Butt-end method was effective as a field treatment technique compared to transpiration method when considered the treatability, easiness of treatment, productivity of treated wood, and environmental aspects related to chemical treatment, regardless of the combination of wood species and chemicals.