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The effect of Youngyanggaksan on the anticonvulsive, antipyretic, analgesic, sedative and GABAergic system (영양각산(羚羊角散)이 진경(鎭痙), 해열(解熱), 진통(鎭痛), 진정(鎭靜) 및 GABAergic system에 미치는 영향)

  • Kim, Jin-Hee;Moon, Byoung-Soon;Sung, Kang-Kyoung
    • Korean Journal of Oriental Medicine
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    • v.2 no.1
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    • pp.205-225
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    • 1996
  • This study has been carried out to investigate the effects of Youngyanggaksan (YGS) extract on the anticonvulsive, antipyretic, anlgesic, sedative and GABAergic system of experimental animals. The results of this study were as follows : 1. YGS extract prolonged significantly the beginning time to convulsion and time to death induced by strychnine. 2. YGS extract prolonged significantly the time to death induced by electrical shock of ECT unit (3sec, 200F, 25mA). 3. On the experiment of hypothermic effects of YGS extract on the rectal temperature of rats, YGS extract decreased significantly the rectal temperature of rats. 4. On the experiment of antipyretic effects of YGS extract on the febrile induced by the subcutaneous injection of $150{\mu}g/kg$ endotoxin in rats, YGS extract decreased significantly the rectal temperature of rats. 5. On the experiment of analgesic effects of YGS extract on the writhing syndrome induced by intraperitoneal injection 0.7% acetic acid 1ml/100g in rats, the writhing syndrome was reduced significantly by administration of YGS extract. 6. On the experiment of sedative effects of YGS extract on spontaneous motor activity measured by wheel cage method in mice, the spontaneous motor activity was reduced significantly by administration of YGS extract. 7. On the experiment of effects of YGS extract on the activity of GABA-transaminase(GABA-T) in rat brains after 21 days of oral administration of YGS extract, the activity of GABA-T was reduced significantly by administration of YGS extract. 8. On the experiment of effects of YGS extract on the activity concentration of GABA in rat brains after 21 days of oral administration of YGS extract the activity concentration of GABA was reduced significantly by administration of YGS extract. 9. On the experiment of effects of YGS extract on the activity of GAD in rat brains after 21 days of oral adminstration of YGS extract, the activity of GAD was reduced significantly by administration of YGS extract. According to the those results, Youngyanggaksan extract reveals the effects on the anticonvulsive, antipyretic, anlgesic, sedative and GABAergic system.

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A Study on Setting Up Work Conditions for Improving Productiviyt of BIM-based Cost Estimation (BIM 견적 작업 생산성 향상을 위한 업무 환경 조성에 관한 연구)

  • Kim, Seong-Ah;Park, Gweon;Song, Byeong-Seob;Choi, Chel-Ho;Chin, Sang-Yoon
    • Korean Journal of Construction Engineering and Management
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    • v.17 no.1
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    • pp.56-65
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    • 2016
  • Many cases have mentioned the effect by applying BIM on the media such as at conferences, workshops, reports, ect. These cases reported that costs could be saved directly by prevention the need to re-do and reconstruct caused by using BIM. BIM users mentioned that using BIM has potential value in saving costs. The benefits of the BIM include intangible value that cannot be estimated in costs, such as reducing work time and improving productivity. However, the financial value of using BIM, such as Return on Investment, has not yet been exposed, and BIM users have a negative view of the financial value of BIM in Korea. Therefore, this study has researched the effects of applying BIM on construction estimate services in view of business productivity, not finance. This study compared the traditional and BIM based estimation, and verified the effect of estimating BIM through work sampling. This study investigated a precondition for getting the effects of BIM based estimation. The results show a need for BIM education, 3D Modeling standards, and database on quantity in order to improve product ivity and reduce work time on BIM based estimation

Conceptualization of Defense Industrial Security in Relation to National Security (국가 안보와 연계한 방위산업 보안 개념 정립)

  • Go, Hee-Jae;Lee, Yong-Joon
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.20 no.12
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    • pp.265-270
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    • 2019
  • In order to protect the advancement of defense technology that has a tremendous e?ect on both the national security and the economy, the Republic of Korea established the Defense Technology Security Act in 2015. As the new enactment brought changes to the landscape of the defense industry and defense industrial security, a new examination of the concept of the defense industrial security has now become necessary. Even after taking into consideration the undisclosed nature of defense industrial security research, and the fact that only the limited number of firms participates in the subject matter, scientific studies related to the topic have not been active. However, with the new enactment of the Defense Technology Security Act, it is necessary to expand the scope of security and to redefine the concept of defense industrial security. In this paper, we analyzed the research works on related technology protection policies and our environment of the defense industry in order to conceptualize defense industrial security. The established concepts are expected to provide a systematic way to protect the confidential and defense technology.

A Study on Transformation of iOS GUI Design in the view of Affordance (iOS GUI 디자인의 변화에 대한 어포던스 관점의 고찰)

  • Yang, Yun;Kim, Hyung Woo
    • Smart Media Journal
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    • v.5 no.4
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    • pp.96-102
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    • 2016
  • The purpose of this study is to investigate the transformation of affordance in iOS GUI design and the relationship of affordances. We figured out variety kinds of Affordance concepts and choosed six Affordances(Visceral, Behavioral, Reflective, Explicit, Metaphorical, Pattern Affordance) Based on the previous studies. The result of investigating the transformation of iOS GUI design which based on the viewpoint of these 6 Affordance we have chosen is as follows. Firstly, the Visceral Affordance of iOS GUI design has already sufficiently become to the Reflective Affordance. So we can ignore or ellipsis the Visceral Affordance and the addition of specific Explicit Affordance can be possible. Secondly, due to the use experience of iOS, Behavioral Affordance and Pattern Affordance have already become to a kind of Reflective Affordance. Through this evolution, new kind of Pattern Affordance is formed. At the mean time, it also applied the basic field of Metaphorical Affordance. Thirdly, investigating the Flat Design of iOS based on the viewpoint of Affordance, we have figured out that Visceral Affordance has been reduced. So that the constrains of visual performance has also been reduced. This is the reason that there are more space remained in screen layout design, the color has become more natural and more Explicit Affordance has been provided, ect. Futhermore, in this thesis we have also figured out that there are some interactions and relationships between each Affordance. With the development of iOS, some Affordances have transformed to other Affordances. With the accumulation of use experience, Visceral Affordance has transformed to Reflective Affordance based on the field of Metaphorical Affordance. With the disappearance or reduction of Visceral Affordance, iOS provide Explicit Affordance instead. As a result of this kind of process, a new Pattern Affordance has been formed.

Characteristics Testing of the ECT Bobbin Probe for Steam Generator Tube Inspection of Nuclear Power Plant (원전 증기발생기 전열관 와전류검사 보빈탐촉자의 특성 시험)

  • Nam, Min-Woo;Lee, Hee-Jong;Cho, Chan-Hee;Yoo, Hyun-Joo
    • Journal of the Korean Society for Nondestructive Testing
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    • v.30 no.4
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    • pp.386-395
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    • 2010
  • The steam generator management program(SGMP) has recently defined the procedures for the qualification of eddy current hardware and technique. These procedures provide two basic methods for qualification. The first way is to qualify the equipment or the probe by using the flaw mechanism and method of the pulled tubes from the heat exchangers or the artificial flawed tubes. The second way is to verify the equivalency with the characteristics of the qualified equipment or probe. In this case, the qualified equipment or probe may be modified to substitute or replace instruments or probes without re-qualification provided that the range of essential variables defined in the examination technique specification sheet are met. This study is to describe the result of the comparative performance evaluation of bobbin coil eddy current probes manufactured by KEPCO Research Institute and probes manufactured by a foreign manufacturer. As a result of this study, although there were minor differences between the two kinds of probes, it was evaluated that the two kinds of probes were almost identical in the significant performance characteristics described in the KEPCO Research Institute guideline.

Changes of Vegetation Structure according to the Hydro-seral Stages in the East Coastal Lagoons, Korea (동해안 석호에서 수생천이계열에 따른 식생구조의 변화)

  • Kim, Hyoe-Young;Kim, Mi-Hee;Choi, Hee-Kyung;Lyang, Doo-Yong;Shin, Eun-Joo;Lee, Kyu-Song;Yi, Hoon-Bok
    • Journal of Wetlands Research
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    • v.12 no.3
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    • pp.129-144
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    • 2010
  • We have studied the changes of the environmental and vegetational factors according to the hydro-seral stages in the shoreline of the lagoons, Korea. We have divided seral stages into 7 stages from open water stage to the stratified forest stage considering as the characteristics of water body, dominance of submerged and emergent plant, and development of the shrub, subtree and tree layer. According to the successional stage, water depth gradually decreased and water quality changed from seawater to brackish water and from brackish water to fresh water, organic matter in a soil layer gradually increased, and the litter layer grew up. As the development of the vegetation structure, the life-form of the vascular plants changed as follows; open water ${\rightarrow}$ submerged plant and floating-leaved plant ${\rightarrow}$ emergent plant and submerged plant ${\rightarrow}$ emergent plant ${\rightarrow}$ emergent plant, mesophyte and scrub ${\rightarrow}$ mesophyte. In the late seral stage, the 3 different forest types were established by the water retention or drainage and nutrient accumulation of the soil layer. Salix dominant forest developed in the wetted sites, the forest type dominated by Pinus thunbergii, Carex pumila and mesophytes developed in the well drained sites causing by sand substrate, and the forest type dominated by the planted or ruderals such as Pinus densiflora, Robinia psedo-acacia, Festuca ovina, Setaria viridis ect. developed in the sites composed of forest soil introduced by artificial reclamation.

Community Structure and Understory Vegetation Distribution Pattern of Fagus engleriana Stand in Is. Ulleung (울릉도 너도밤나무림의 군집구조와 하층식생의 분포특성)

  • Cheon, Kwang-Il;Jung, Sung-Cheol;Lee, Chang-Woo;Byeon, Jun-Gi;Joo, Sung-Hyun;You, Ju-Han;Lee, Seul-Gi;Choi, Cheol-Hyun;Park, In-Hwan
    • Journal of the Korean Society of Environmental Restoration Technology
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    • v.15 no.4
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    • pp.81-95
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    • 2012
  • This study was intended for Fagus engleriana stand in Is. Ulleung where the disturbance of vegetation has been caused by the exploitation and the increase of tourists. For the effective conservation and management on this issue, this study was conducted provide basic data. The sixteen study sites ($20{\times}20m$) were installed in the dominant Fagus engleriana stand and the base environment and vegetation were investigated. The Fagus engleriana stand was classified into two groups, The Fagus engleriana stand was classified into two groups, community A is Fagus engleriana-Sorbus amurensis and community B is Fagus engleriana-Acer pictum subsp. Mono by cluster analysis and community A were nothing signigicant by indicator species analysis. Community B were Eight species (Tsuga sieboldii, Camellia japonica, Dystaenia takesimana ect.) significant by indicator species analysis. The diameter class of 16cm to 25cm was 53.7% in population structure of Fagus engleriana, which was the highest and showed inverse J-distribution. Species diversity index (H') of investigated woody layer group ranged from 0.99 to 2.05 and that of under layer group ranged from 1.75~2.59. According to Non-metric Multidimensional Scaling (NMS) analysis, the woody layer was divided into community A developed in the region having relatively high sand content at high altitudes and community B formed at the place having relatively high clay content at low altitudes. Then this classification was significant through Multi-Response Permutation Procedures (MRPP) analysis. The distribution of understory vegetation through Detrended Correspondence Analysis (DCA) was induced by the silt content and cover degree of vegetation layer.

Analysis of Core Patent and Technology of Unmanned Ground Technology Using an Analytical Method of the Patent Information (특허정보 분석 방법을 이용한 지상무인화 기술 분야 핵심 특허 및 기술 분석)

  • Park, Jae Yong
    • KIPS Transactions on Software and Data Engineering
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    • v.7 no.5
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    • pp.189-194
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    • 2018
  • Unmanned technology is a representative technology that integrates various technologies like electric, electronic, mechanical, artificial intelligence, ICT technology, ect. In special emphasize, ground technology has been developing exponentially in the military field and expanding its utilization area. The patent information analysis method presented in this study, proposes a new patent analysis methodology for patent information analysis and patent information on unmanned ground technology. The patent information analysis processor has 6 levels to extract core patents and technologies. The process consists of: selection of technology to be analyzed, classification of detailed technology / key keyword selection, patent information collection / noise reduction, selection of patent information analysis method, patent information analysis, finally, core patents and key technologies that are extracted. Patent information on unmanned ground technology is also analyzed in this study. First, the technical classification of ground unmanned technology is carried out in detail. The core technology and core patents of ground unmanned technology were extracted through CPP and IPC code connectivity analysis. The results of patent information analysis using proposed patent information analysis method that can be applied to various fields of technology and analysis. These can be used as a material to forecast the direction of future research and development on the technology to be analyzed.

Clinical Study on the Effect of Bee Venom Acupuncture Therapy on the Post-stroke Pain (뇌졸중 후 중추성 통증 환자에 대한 봉독약침요법약침 치료 효과에 대한 임상적 연구)

  • Jeoung, Kyoung-suk;Kim, Su-hyun;Park, Seon-kyeong;Lim, Ho-jae;Yoon, Hyoung-seon;Ahn, Ho-jin
    • Journal of Acupuncture Research
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    • v.22 no.3
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    • pp.69-75
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    • 2005
  • Objective : This study is designed to find out the effect of Bee Venom Acupuncture Therapy on the Post-stroke Pain. Methods : Bee venom solution was injected on Seven Points of CVA-GB2l(肩井), LI15(肩隅), Ll11(曲池), GB31(風市), ST36(足三里), GB39(絶骨), ect- every other day for 3 weeks, in twenty patients who were admitted in Dong-Seo Oriental Medical Hospital, as diagnosed by their typical pain characteristics of central pain from stroke. Result : After 3 weeks treatment, visual analogue scale of pain severity showed significant decrease.

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Needs for Sex Knowledge in Adolescents (청소년의 성지식 요구)

  • Lee Eun Joo
    • Child Health Nursing Research
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    • v.5 no.2
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    • pp.211-234
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    • 1999
  • The purpose of this article was to get hold of adolescent's needs for sex knowledge and to reveal their understanding of sex. These results may be applied to the sex education and counselling for adolescent. The participants of study were 267 students (females, 144 ; males, 123) who were the first and second grade form 1 middle and 2 high schools. They were asked to describe 3 questions that they wanted to know or to learn about sex. Their questions about sex were total 779(girls, subtotal 456, mean 3.2, boys, subtotal 323, mean, 2.6). These questions categorized to 9 items by content analysis. The items were ‘sexual drive, behavior and tendency(229, 29.4%)’ , ‘anatomy and physiology of reproductive system(140, 18.0%)’, ‘reproduction(131, 16.8%)’, ‘concept of sex(31, 4.0%)’, ‘acquaintance between the other sexes(17, 2.2%)’, and ‘the others(9, 1.2%)’ in order of frequency. The most frequent item that the student want to know or team about sex was ‘sexual drive, behavior and tendency’ except girls of sophomore in middle school. There were several features in participants' needs for sex knowledge as respects of the understanding of sex- biological sex, gender, and sexuality. The prominent feature in knowledge need of bio logical sex was that the participants had the interests according to their biological sex. They had the negative attitude to the phenomenons (ex, menstruation and pregnancy, phimosiectomy, etc) that they experienced or would experience due to their biological sex. A part of them asked the questions based the misconceptions and used the slangs or ‘××’, ect. to name the male or female genitalia. The male students wanted to know the female genitalia. The participants' understanding of gender reflected the sexism of our society, but they didn't accept and had doubts about the dual, hierarchical structure of that. The students, especially female seemed to be powerless to the harms of the sexual violence. Girls had much interest in their appearances and complained to our sexual culture that women comforted and served men. The participants had the dual perspective that the sexuality as respects of physiologic phenomenon was considered as natural but that as related to heterosexuals was as negative. And they deemed that men's sexual drive was stronger than women's and was difficult or was not able to be inhibited. They had much interests in homosexuality but reflected the negative attitude to that in our society. Adolescent felt wonder why the expressions of sexuality of adult were permitted but theirs were not. Lastly, a part of boys substituted querying the sexuality of animals for asking that of human. Maybe it was because of the embarrassment to talk about human's sexuality directly. The teenaged participants understood that the sex had not only the biological meanings but also the sociocultural meanings. They regarded the sex as natural and wanted to know it, but they had conceptions that it was difficult and embarrass to talk about it openly and directly.

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