• International Journal of Computer Science & Network Security
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• 제22권12호
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• pp.239-244
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• 2022

The study aimed to build a program in activities for early childhood students to develop some of the basic skills necessary for the age of artificial intelligence, to achieve the objectives of the study , the researcher used the experimental design, and the research sample consisted of 37 early childhood students. The study used the following tools: Experimental treatment subject: the proposed program in the activities, Measurement and evaluation tool: testing the basic skills needed for the age of artificial intelligence. The study concluded several results: There is a statistically significant difference (α≤0.05) between the average grades of the early childhood students in the research group in the tribal and remote measurements to test the basic skills necessary for the age of artificial intelligence in favor of the students grades in the dimensional measurements. Practical application of the study through benefiting from the proposed program of activities prepared in the current study in planning and implementing activities to develop the basic skills necessary for the age of artificial intelligence among early childhood students.

• 대한족부족관절학회지
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• 제22권2호
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• pp.78-81
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• 2018

This paper presents a case of an early malignant transformation of untreated ulcers in a patient with diabetes. This case shows that Marjolin's ulcer can occur not only after chronic injury, but can also develop in the early stages after the onset. Hence, an early biopsy for diabetic foot ulcers that fail to heal with acute treatment can enable an earlier diagnosis and treatment without amputation, resulting in a better quality of life for the patient.

• Journal of Gastric Cancer
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• 제9권2호
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• pp.39-45
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• 2009

국내에서 조기위암에 대한 내시경절제술은 잘 선택된 환자에서 적용시 매우 좋은 성적을 보이는 치료법으로 중요한 치료로 자리를 잡았다. 그러나 내시경절제술의 적응증, 최선의 치료 술기, 합병증의 예방과 치료 및 추적관찰 등의 분야에서 아직 명확히 확립되지 못한 부분이 있다. 최근 국내에서 조기위암 내시경절제술에 대한 대규모의 다기관 연구의 성적들이 보고되지 시작하였다. 내시경 점막 절제술이 최소 침습 시술이고 수술과 달리 시술 후 장기 보존이 가능해 환자의 삶의 질이 우수하다는 점, 최근 내시경 시술과 기기의 발전으로 인해 절제 가능한 병변의 크기에 제한이 없어지고 있다는 점 등을 고려할 때 내시경 점막 절제술은 국내에서 조기 위암 치료의 중요한 치료 수단으로서 그 역할이 점차 확대될 것으로 기대된다. 본고에서는 조기위암 내시경 절제술에 대한 최근 국내 결과를 요약하고 향후 발전방향에 대하여 살펴보고자 한다.

• Journal of Gastric Cancer
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• 제17권1호
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• pp.88-92
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• 2017

Early detection and treatment decrease the mortality rate associated with gastric cancer (GC). However, the natural history of GC remains unclear. An 85-year-old woman was referred to our hospital for evaluation of a gastric tumor. Esophagogastroduodenoscopy identified a 6 mm, flat-elevated lesion at the lesser curvature of the antrum. A biopsy specimen showed a well-differentiated tubular adenocarcinoma. The depth of the lesion was estimated to be intramucosal. Although the lesion met the indications for endoscopic resection, periodic endoscopic follow-up was performed due to the patient's advanced age and comorbidities. The mucosal GC invaded into the submucosa 3 years later, and finally progressed to advanced cancer 5 years after the initial examination. The patient died of tumor hemorrhage 6.4 years after the initial examination. In this case, mucosal GC progressed to advanced GC, eventually leading to the patient's death from GC. Early and appropriate treatment is required to prevent GC-related death.

• Journal of Chest Surgery
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• 제9권2호
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• pp.125-132
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• 1976

The author made clinical study of 100 cases of empyema in infancy and childhood that were treated at the Department of Chest Surgery, Busan University Hospital and Busan Children's Charity Hospital, from Jan 1962 to Nov. 1975. 1. In infancy and childhood, 62 cases out of my 100 cases of empyema were caused by .staphylococci and most of recent reports showed a gradual increase in number of staphylococcal empyema. 2. Most frequent lesion predisposing to empyema in infancy and childhood was pneumonia (72%), being remarkable in staphylococcal empyema (85.5%) to that of others. 3. Antibiotics sensitivity test for staphylococci revealed that the erythromycin was most susceptible (85. 5%). 4. The mortality rate was 6% in over all and the author believes that from the point of view of surgical treatment, failure of early continuous drainage on account of multiple thoracentesis for the early stage of empyema, and also early open thoracotomy procedure such as decortication were all the contributing factors to higher mortality in the empyema of infancy and childhood. 5. It may be concluded that the treatment of choice for empyema in infancy and childhood were early and prolonged continuous drainage of pus by closed thoracotomy with caution and administration of more susceptible antibiotics with nutritional support.

• Journal of Korean Neurosurgical Society
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• 제58권3호
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• pp.304-307
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• 2015

Only a few cases of anterior longitudinal ligament (ALL) injury related with retropharyngeal hematoma without fracture have previously been reported. The treatment of choice for retropharyngeal hematoma is generally considered to be conservative care, but we believe that early surgery of this pathology would be better in certain situations. Here, we describe two cases with life-threatening large retropharyngeal hematomas related with ALL injuries and operated on at an early stage. Two previously healthy patients visited the emergency room with neck pain and dyspnea after falling. Serious neck swelling was observed and lateral neck X-ray showed severe widening of the prevertebral space. Due to dyspnea progression, emergency endotracheal intubation was performed. Although there was no primary cause of the retropharyngeal hematoma on preoperative examination, ALL tearing was intraoperatively confirmed during early surgery. The in-hospital evolutions of the patients were favorable after surgery. We should bear in mind the possibility of ALL injury and perform early surgery where possible given the earlier convalescence and good prognosis.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제17권1호
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• pp.73-81
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• 1995

The poor survival rates of patients with carcinoma of a tongue, despite of modern therapy, is well recognized. One of the most important prognostic factors is status of the cervical lymph nodes. There have been a long-standing debate about the treatment of cervical lymph nodes in early-stage tongue cancer. There are two major treatment opinion. The one is surgical excision of primary tumor with prophylactic neck dissection, simultaneously, and the other is to delay the cervical therapy until cervical lymph node is palpable. Recently we have experienced the early cervical metastasis in three patients who had been diagnosed as a carcinoma of the tongue. They were T1, T2 lesion and no palpable node was found. But histopathologic examination showed the occult metastasis or delayed cervical metastasis was occured. By the review of literature and clinical experience, we could conclude the prophylactic neck dissection offers a better chance for success than therapeutic neck dissection of palpable lymph nodes, in case of oral tongue cancer.

• Asian Pacific Journal of Cancer Prevention
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• 제13권4호
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• pp.1699-1703
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• 2012

Cervical cancer remains the most frequent cancer in women from the developing world. More than 88% of deaths occur in low-income countries, and it is predicted to climb to 91.5% by 2030. Although Pap-based screening programmes have shown to be effective in reducing the disease burden in high-resource countries, implementation and sustention of cytology-based programmes is quite challenging in low-resource settings. The present paper reviews evidence-based alternatives of screening methods, triaging algorithm, treatment of cervical precancerous lesions, and age-group at screening appropriate for low-income countries. Evidence shows that visual inspection methods using diluted acid acetic or Lugol's iodine, and HPV-DNA testing are more sensitive tests than the Pap-smear screening test. Visual inspection allows an immediate result and, when appropriate, may be immediately followed by cryotherapy, the so called "screen-and-treat" approach, achieved in a single visit, by trained nurses and midwives. Examples of cervical cancer prevention programmes in India and selected low-income countries are given.

• 한국어병학회지
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• 제16권1호
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• pp.39-49
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• 2003

Cytosolic oxidation by 4-hydroxy-2-nonenal (4HNE) and tert-butyl hydroperoxide (t-BHP) results in cell death of bovine aortic endothelial cells (BAEC). In this study, we have investigated the roles of antioxidants such as 2,3,6-tribromo-4,5-dihydroxy benzyl methyl ether (TDB) and phloroglucinol in preventing cell death. After treatment with oxidants for 6h, cells became compact and showed nuclear condensation, which were characteristics of early apoptosis. After l2h treatment, morphologic features including severe cytoplasm condensation, membrane blebbing, and apoptotic bodies were prominent and these findings were interpreted as characteristics of late-apoptosis. When the apoptotic cells were treated with antioxidants for 12h, both early and late apoptotic cells did show no significant change. After oxidant treated cells were incubated with antioxidant for 24h, the characteristics of early-apoptosis were eliminated but cells in lateapoptosis could not return to normal cells. These results suggest that TDB and phloroglucinol prevent the cells from dying through apoptosis induced by 4HNE and t-BHP in early stage.

• 한국초지조사료학회지
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• 제17권1호
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• pp.59-66
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• 1997

This experiment was conducted at the forage experimental field, College of Agriculture and Life Sciences, Seoul National University, Suweon in 1992 and 1993 to investigate the effects of tillage method-conventional and rotary-till, rye (Secde cereale L.) harvest date-early (April 14) and late (April 26), and rye residue treatmentno paraquat(1, 1-dinethyl-4,4'-bipyridinium dichloride) and paraquat in minimizing the adverse effects of the rye residue on growth and yield of succeeding corn(Zea mays L.). Corn plant height during the growing season was slighly taller with conventional tillage relative to rotary-till when rye was harvested in early and treated by paraquat. Corn LA1 during the growing season was slighly increased when rye was harvested in early and where conventional tillage was used with paraquat treatment. There were no differences in the leaf number and silking dates of corn among the tillage methods, harvest dates of rye and paraquat treatments. The dry matter yield of corn was significantly increased by paraquat treatment when rye was harvest in early, but no differences were found in the dry matter percentage, ear percent to total dry matter, and stover, ear and estimated TDN yields of corn among the treatments.