• 제목/요약/키워드: early identification

검색결과 667건 처리시간 0.024초

Feasibility of Revision Cochlear Implant Surgery for Better Speech Comprehension

  • Hwang, Kyurin;Lee, Jae Yong;Oh, Hyeon Seok;Lee, Byung Don;Jung, Jinsei;Choi, Jae Young
    • Journal of Audiology & Otology
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    • 제23권2호
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    • pp.112-117
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    • 2019
  • Background and Objectives: The purpose of this study was to evaluate the efficacy of revision cochlear implant (CI) surgery for better speech comprehension targeting patients with low satisfaction after first CI surgery. Subjects and Methods: Eight patients who could not upgrade speech processors because of an too early CI model and who wanted to change the whole system were included. After revision CI surgery, we compared speech comprehension before and after revision CI surgery. Categoies of Auditory Performance (CAP) score, vowel and consonant confusion test, Ling 6 sounds, word and sentence identification test were done. Results: The interval between surgeries ranged from eight years to 19 years. Same manufacturer's latest product was used for revision surgery in six cases of eight cases. Full insertion of electrode was possible in most of cases (seven of eight). CAP score (p-value=0.01), vowel confusion test (p-value=0.041), one syllable word identification test (p-value=0.026), two syllable identification test (p-value=0.028), sentence identification test (p-value=0.028) had significant improvement. Consonant confusion test (p-value=0.063), Ling 6 sound test (p-value=0.066) had improvement but it is not significant. Conclusions: Although there are some limitations of our study design, we could identify the effect of revision (upgrade) CI surgery indirectly. So we concluded that if patient complain low functional gain or low satisfaction after first CI surgery, revision (device upgrade) CI surgery is meaningful even if there is no device failure.

Feasibility of Revision Cochlear Implant Surgery for Better Speech Comprehension

  • Hwang, Kyurin;Lee, Jae Yong;Oh, Hyeon Seok;Lee, Byung Don;Jung, Jinsei;Choi, Jae Young
    • 대한청각학회지
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    • 제23권2호
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    • pp.112-117
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    • 2019
  • Background and Objectives: The purpose of this study was to evaluate the efficacy of revision cochlear implant (CI) surgery for better speech comprehension targeting patients with low satisfaction after first CI surgery. Subjects and Methods: Eight patients who could not upgrade speech processors because of an too early CI model and who wanted to change the whole system were included. After revision CI surgery, we compared speech comprehension before and after revision CI surgery. Categoies of Auditory Performance (CAP) score, vowel and consonant confusion test, Ling 6 sounds, word and sentence identification test were done. Results: The interval between surgeries ranged from eight years to 19 years. Same manufacturer's latest product was used for revision surgery in six cases of eight cases. Full insertion of electrode was possible in most of cases (seven of eight). CAP score (p-value=0.01), vowel confusion test (p-value=0.041), one syllable word identification test (p-value=0.026), two syllable identification test (p-value=0.028), sentence identification test (p-value=0.028) had significant improvement. Consonant confusion test (p-value=0.063), Ling 6 sound test (p-value=0.066) had improvement but it is not significant. Conclusions: Although there are some limitations of our study design, we could identify the effect of revision (upgrade) CI surgery indirectly. So we concluded that if patient complain low functional gain or low satisfaction after first CI surgery, revision (device upgrade) CI surgery is meaningful even if there is no device failure.

다중 역전사-루프매개등온증폭법(RT-LAMP)를 이용한 생물 독소 유전자 신속 진단법 (Rapid, Simultaneous Detection of Various Biological Toxin Genes Using Multiplex Reverse Transcription Loop-Mediated Isothermal Amplification(RT-LAMP))

  • 이승호;정찬호;구세훈;김정은;윤형석;이대상;허경행;송동현
    • 한국군사과학기술학회지
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    • 제27권4호
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    • pp.516-527
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    • 2024
  • Rapid, early, accurate detection and identification of the various pathogenic agents associated with the development of biological weapons is critical in preventing loss of life and limiting the impact of these organisms when used against civilian or military targets. The aim of this study was to produce a system for the simple, rapid, accurate and simultaneous detection and identification of Ricin, Botulinum toxin B and Staphylococcal enterotoxin B as a proof of principle for developing field appropriate reverse transcription loop-mediated isothermal amplification systems for the accurate identification of potential biological threats. These systems were designed to facilitate the identification of potential threats even in remote or resource-limited locations.

드론 식별 시스템을 위한 합성곱 신경망 기반 이미지 분류 모델 성능 비교 (Performance Comparison of CNN-Based Image Classification Models for Drone Identification System)

  • 김영완;조대균;박건우
    • 문화기술의 융합
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    • 제10권4호
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    • pp.639-644
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    • 2024
  • 최근 전장에서의 드론 활용이 정찰뿐만 아니라 화력 지원까지 확장됨에 따라, 드론을 조기에 자동으로 식별하는 기술의 중요성이 더욱 증가하고 있다. 본 연구에서는 드론과 크기 및 외형이 유사한 다른 공중 표적들인 새와 풍선을 구분할 수 있는 효과적인 이미지 분류 모델을 확인하기 위해, 인터넷에서 수집한 3,600장의 이미지 데이터셋을 사용하고, 세 가지 사전 학습된 합성곱 신경망 모델(VGG16, ResNet50, InceptionV3)의 특징 추출기능과 추가 분류기를 결합한 전이 학습 접근 방식을 채택하였다. 즉, 가장 우수한 모델을 확인하기 위해 세 가지 사전 학습된 모델(VGG16, ResNet50, InceptionV3)의 성능을 비교 분석하였으며, 실험 결과 InceptionV3 모델이 99.66%의 최고 정확도를 나타냄을 확인하였다. 본 연구는 기존의 합성곱 신경망 모델과 전이 학습을 활용하여 드론을 식별하는 새로운 시도로써, 드론 식별 기술의 발전에 크게 기여 할 것으로 기대된다.

초기 벨마비에서 나타나는 탈신경의 시간경과에 따른 변화: 전기생리학적 검사를 통한 확인 (Time course of the denervation in early stage of Bell's palsy.: Identification by electrophysiologic study)

  • 배종석;엄근용;김병준;권기한
    • Annals of Clinical Neurophysiology
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    • 제6권1호
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    • pp.26-30
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    • 2004
  • Background: Electrophysiologic study accurately predicts the degree of degenerated motor axons but cannot give precise information on the type of injury that occurred in Bell's palsy. Because of these limitation for prognostic prediction in Bell's palsy, we evaluated divergence of electrophysiological time course for the purpose of presuming the type of injury in Bell's palsy. Methods: We did bilateral facial nerve conduction studies in 103 Bell's palsy patients, who visited to Han-Gang sacred heart hospital from 1998 to 2001. We compared the CMAP amplitude of disease site with that of normal site and suggested that decremental CMAP amplitude ratio (percentage) as a degree of denervation of affected facial nerve. Then we demonstrated the time course of denervation percentage. After defining normal range of CMAP amplitude difference from normal control group, we also evaluated if distinct time course of early minimal denervation is present. Results: Our results show that time course of the denervation in early stage of Bell's palsy reflect various injury type such as axonotmesis, neurotmesis or other unidentified type. We cannot identify the distinct time course of early minimal denervation. Conclusions: The time course as well as the maximal value of denervation are the best prognostic guidelines in Bell' s palsy. So repeated serial electrophysiologic test are inevitable to assess prognosis. As an another topic, early minimal denervation for prognostic prediction deserve to be evaluated as a future work up for prognostic prediction.

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Novel Algorithms for Early Cancer Diagnosis Using Transfer Learning with MobileNetV2 in Thermal Images

  • Swapna Davies;Jaison Jacob
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • 제18권3호
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    • pp.570-590
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    • 2024
  • Breast cancer ranks among the most prevalent forms of malignancy and foremost cause of death by cancer worldwide. It is not preventable. Early and precise detection is the only remedy for lowering the rate of mortality and improving the probability of survival for victims. In contrast to present procedures, thermography aids in the early diagnosis of cancer and thereby saves lives. But the accuracy experiences detrimental impact by low sensitivity for small and deep tumours and the subjectivity by physicians in interpreting the images. Employing deep learning approaches for cancer detection can enhance the efficacy. This study explored the utilization of thermography in early identification of breast cancer with the use of a publicly released dataset known as the DMR-IR dataset. For this purpose, we employed a novel approach that entails the utilization of a pre-trained MobileNetV2 model and fine tuning it through transfer learning techniques. We created three models using MobileNetV2: one was a baseline transfer learning model with weights trained from ImageNet dataset, the second was a fine-tuned model with an adaptive learning rate, and the third utilized early stopping with callbacks during fine-tuning. The results showed that the proposed methods achieved average accuracy rates of 85.15%, 95.19%, and 98.69%, respectively, with various performance indicators such as precision, sensitivity and specificity also being investigated.

응답 라운드 조기종료와 전송확률 제어를 통한 STAC 프로토콜의 성능 개선 (Performance Improvement of STAC Protocol by Early Release of Reply Round and Transmission Probability Control)

  • 임인택
    • 한국정보통신학회논문지
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    • 제17권11호
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    • pp.2569-2574
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    • 2013
  • Auto-ID 센터에서는 13.56MHz RFID 시스템에서 다중 태그를 식별하기 위한 충돌 방지 알고리즘으로 STAC 프로토콜을 제안하였다. STAC 프로토콜에서는 다음 응답 라운드의 슬롯 개수를 결정하기 위하여 태그 수 추정 기법을 적용한다. 이 경우 추정한 태그의 수에 오차가 발생하면 충돌 또는 빈 슬롯이 많이 발생할 수 있으므로 식별 성능이 저하되는 문제점이 있다. 따라서 본 논문에서는 응답 라운드 동안 빈번한 충돌 또는 빈 슬롯이 발생하면 응답 라운드를 종료하는 기법과 태그의 전송확률을 제어하는 기법을 적용한 ERPB 알고리즘을 제안하고, 이에 대한 성능을 분석한다. 시뮬레이션을 통한 성능분석의 결과, 제안한 기법은 충돌률이 STAC 프로토콜에 비하여 39% 정도 낮으므로 태그 식별 시간이 짧음을 알 수 있었다.

정맥용 면역글로불린 투여로 호전된 항-$Di^a$ 항체에 의한 신생아 용혈성 질환 1예 (A Case of Hemolytic Disease of a Newborn by an Anti-$Di^a$ Antibody Treated with Intravenous Immunoglobulin)

  • 이창언;박수진;김원덕
    • Journal of Yeungnam Medical Science
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    • 제30권1호
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    • pp.21-24
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    • 2013
  • Hemolytic disease in a newborn that causes early jaundice is common. It is often due to the Rh (D) and ABO incompatibility, but rarely due to unexpected antibodies. Among these unexpected antibodies, the anti-$Di^a$Dia antibody rarely occurs. The anti-$Di^a$ antibody was observed in the serum and red-cell eluate of an infant, and in the serum of his mother. The frequency of the appearance of the $Di^a$ antigen in the Korean population is estimated to be 6.4-14.5%. This paper reports a case of hemolytic disease in a newborn associated with the anti-$Di^a$ antibody. A full-term male infant was transferred to the authors' hospital due to hyperbilirubinemia the day after his birth. The laboratory data indicated a hemoglobin value of 11.6 g/dL, a reticulocyte count of 10.6%, a total bilirubin count of 14.4 mg/dL, a direct bilirubin count of 0.6 mg/dL, and a positive result in the direct Coombs' test. Due to the identification of an irregular antibody from the maternal serum, an anti-$Di^a$ antibody was detected, which was also found in the eluate made from the infant's blood. The infant had been treated with phototherapy and intravenous immunoglobulin since the second day after his birth and was discharged due to an improved condition without exchange transfusion. Therefore, in cases of iso-immune hemolytic disease in a newborn within 24 hours from birth who had a negative result in an antibody screening test, the conduct of an anti-$Di^a$ antibody identification test is recommended due to the suspicion of an anti-$Di^a$ antigen, followed by early administration of intravenous immunoglobulin.

Molecular characterization of reciprocal crosses of Aerides vandarum and Vanda stangeana (Orchidaceae) at the protocorm stage

  • Kishor, Rajkumar;Devi, H.S.;Jeyaram, K.;Singh, M.R.K.
    • Plant Biotechnology Reports
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    • 제2권2호
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    • pp.145-152
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    • 2008
  • Aerides vandarum and Vanda stangeana are two rare and endangered vandaceous orchids with immense floricultural traits. The intergeneric hybrids were synthesized by performing reciprocal crosses between them. In vitro germination response of the immature hybrid embryos was found to be best on half-strength Murashige and Skoog medium supplemented with 20% (v/v) coconut water/liquid endosperm from tender coconut. Determination of hybridity was made as early as the immature seeds or embryos germinated in vitro, using randomly amplified polymorphic DNA (RAPD) markers. Out of 15 arbitrarily chosen decamer RAPD primers, two were found to be useful in amplification of polymorphic bands specific to the parental species and their presence in the reciprocal crosses. However, a decisive profile that can identify the reciprocal crosses could not be provided by RAPD. Amplification of the trnL-F non-coding regions of chloroplast DNA of the parent species and hybrids aided easy identification of the reciprocal crosses from the fact that maternal inheritance of chloroplast DNA held true for these intergeneric hybrids. Subsequent restriction digestion of the polymerase chain reaction (PCR) amplified trnL-F non-coding regions of chloroplast DNA also consolidated the finding. Such PCR-based molecular markers could be used for early determination of hybridity and easy identification of the reciprocal crosses.

Performance of mid-upper arm circumference to diagnose acute malnutrition in a cross-sectional community-based sample of children aged 6-24 months in Niger

  • Marshall, Sarah K;Monarrez-Espino, Joel;Eriksson, Anneli
    • Nutrition Research and Practice
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    • 제13권3호
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    • pp.247-255
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    • 2019
  • BACKGROUND/OBJECTIVES: Accurate, early identification of acutely malnourished children has the potential to reduce related child morbidity and mortality. The current World Health Organisation (WHO) guidelines classify non-oedematous acute malnutrition among children under five using Mid-Upper Arm Circumference (MUAC) or Weight-for-Height Z-score (WHZ). However, there is ongoing debate regarding the use of current MUAC cut-offs. This study investigates the diagnostic performance of MUAC to identify children aged 6-24 months with global (GAM) or severe acute malnutrition (SAM). SUBJECTS/METHODS: Cross-sectional, secondary data from a community sample of children aged 6-24 months in Niger were used for this study. Children with complete weight, height and MUAC data and without clinical oedema were included. Using WHO guidelines for GAM (WHZ < -2, MUAC < 12.5 cm) and SAM (WHZ < -3, MUAC < 11.5 cm), the sensitivity (Se), specificity (Sp), predictive values, Youden Index and Receiver Operating Characteristic (ROC) curves were calculated for MUAC when compared with the WHZ reference criterion. RESULTS: Of 1161 children, 23.3% were diagnosed with GAM using WHZ, and 4.4% with SAM. Using current WHO cut-offs, the Se of MUAC to identify GAM was greater than for SAM (79 vs. 57%), yet the Sp was lower (84 vs. 97%). From inspection of the ROC curve and Youden Index, Se and Sp were maximised for MUAC < 12.5 cm to identify GAM (Se 79%, Sp 84%), and MUAC < 12.0 cm to identify SAM (Se 88%, Sp 81%). CONCLUSIONS: The current MUAC cut-off to identify GAM should continue to be used, but when screening for SAM, a higher cut-off could improve case identification. Community screening for SAM could use MUAC < 12.0 cm followed by appropriate treatment based on either MUAC < 11.5 cm or WHZ < -3, as in current practice. While the practicalities of implementation must be considered, the higher SAM MUAC cut-off would maximise early case-finding of high-risk acutely malnourished children.