• Title/Summary/Keyword: early ages

Search Result 750, Processing Time 0.021 seconds

Implantable cardioverter defibrillator therapy in pediatric and congenital heart disease patients: a single tertiary center experience in Korea

  • Jin, Bo Kyung;Bang, Ji Seok;Choi, Eun Young;Kim, Gi Beom;Kwon, Bo Sang;Bae, Eun Jung;Noh, Chung Il;Choi, Jung Yun;Kim, Woong Han
    • Clinical and Experimental Pediatrics
    • /
    • v.56 no.3
    • /
    • pp.125-129
    • /
    • 2013
  • Purpose: The use of implantable cardioverter defibrillators (ICDs) to prevent sudden cardiac death is increasing in children and adolescents. This study investigated the use of ICDs in children with congenital heart disease. Methods: This retrospective study was conducted on the clinical characteristics and effectiveness of ICD implantation at the department of pediatrics of a single tertiary center between 2007 and 2011. Results: Fifteen patients underwent ICD implantation. Their mean age at the time of implantation was $14.5{\pm}5.4$ years (range, 2 to 22 years). The follow-up duration was $28.9{\pm}20.4$ months. The cause of ICD implantation was cardiac arrest in 7, sustained ventricular tachycardia in 6, and syncope in 2 patients. The underlying disorders were as follows: ionic channelopathy in 6 patients (long QT type 3 in 4, catecholaminergic polymorphic ventricular tachycardia [CPVT] in 1, and J wave syndrome in 1), cardiomyopathy in 5 patients, and postoperative congenital heart disease in 4 patients. ICD coils were implanted in the pericardial space in 2 children (ages 2 and 6 years). Five patients received appropriate ICD shock therapy, and 2 patients received inappropriate shocks due to supraventricular tachycardia. During follow-up, 2 patients required lead dysfunction-related revision. One patient with CPVT suffered from an ICD storm that was resolved using sympathetic denervation surgery. Conclusion: The overall ICD outcome was acceptable in most pediatric patients. Early diagnosis and timely ICD implantation are recommended for preventing sudden death in high-risk children and patients with congenital heart disease.

Success of a Cervical Cancer Screening Program: Trends in Incidence in Songkhla, Southern Thailand, 1989-2010, and Prediction of Future Incidences to 2030

  • Sriplung, Hutcha;Singkham, Phathai;Iamsirithaworn, Sopon;Jiraphongsa, Chuleeporn;Bilheem, Surichai
    • Asian Pacific Journal of Cancer Prevention
    • /
    • v.15 no.22
    • /
    • pp.10003-10008
    • /
    • 2014
  • Background: Cervical cancer has been a leading female cancer in Thailand for decades, and has been second to breast cancer after 2007. The Ministry of Public Health (MoPH) has provided opportunistic screening with Pap smears for more than 30 years. In 2002, the MoPH and the National Health Security Office provided countrywide systematic screening of cervical cancer to all Thai women aged 35-60 years under universal health care coverage insurance scheme at 5-year intervals. Objectives: This study characterized the cervical cancer incidence trends in Songkhla in southern Thailand using joinpoint and age period cohort (APC) analysis to observe the effect of cervical cancer screening activities in the past decades, and to project cervical cancer rates in the province, to 2030. Materials and Methods: Invasive and in situ cervical cancer cases were extracted from the Songkhla Cancer Registry from 1990 through 2010. Age standardized incidence rates were estimated. Trends in incidences were evaluated by joinpoint and APC regression models. The Norpred package was modified for R and was used to project the future trends to 2030 using the power of 5 function and cut trend method. Results: Cervical cancer incidence in Songkhla peaked around 1998-2000 and then dropped by -4.7% per year. APC analysis demonstrated that in situ tumors caused an increase in incidence in early ages, younger cohorts, and in later years of diagnosis. Conclusions: Both joinpoint and APC analysis give the same conclusion in continuation of a declining trend of cervical cancer to 2030 but with different rates and the predicted goal of ASR below 10 or even 5 per 100,000 women by 2030 would be achieved. Thus, maintenance and improvement of the screening program should be continued. Other population based cancer registries in Thailand should analyze their data to confirm the success of cervical cancer screening policy of Thailand.

Demographic Survey of Four Thousand Patients with 10 Common Cancers in North Eastern Iran over the Past Three Decades

  • Nikfarjam, Zahra;Massoudi, Toktam;Salehi, Maryam;Salehi, Mahta;Khoshroo, Fahimeh
    • Asian Pacific Journal of Cancer Prevention
    • /
    • v.15 no.23
    • /
    • pp.10193-10198
    • /
    • 2015
  • Background: Cancer is a major cause of mortality in developing countries and correct and valid information about the epidemiology of this disease is the first step in the planning of health care in each region. The aim of this study was to determine the relative frequency, mean age and sex ratio of the most 10 common non-skin cancers in the world and Iran, among patients referred to an oncology clinic. Materials and Methods: This descriptive study was conducted in Mashhad, north east of Iran. The data obtained from the records of patients referred to the private oncology center between the years of 1985-2012". According to the latest report of GLOBOCAN study commonest malignancies included were lung, breast, colorectal, prostate, stomach, liver, cervix, esophageal, bladder cancers and Non-Hodgkin lymphoma. Results: A total of 4,606 cases were analyzed. The mean age was $55.5{\pm}13.8years$ (male: $59.5{\pm}13.9$, female: $52.6{\pm}12.9$). Overall, breast cancer (1,264 cases, relative frequency of 27.4%) was the most prevalent cancer; however the mean ages of diagnosis were not significantly different between 5-year time period divisions (p=0.290). The most common cancer in men was esophageal cancer (26.3%).The lowest mean age was related to women diagnosed with breast cancer ($48.5{\pm}11.8$) and men with non-Hodgkins lymphoma ($48.4{\pm}17.8$). There were statistically significant differences between the mean age of men and women with gastric (p=0.003) and esophageal cancers (p<0.001). Male to female sex ratios in our study for bladder, lung and stomach cancers were 6.57, 2.60 and 2.50 respectively. Conclusions: The results showed that breast cancer tends to be found in younger female patients and bladder cancer appears more often in men. Screening in target population in addition to early diagnosis may reduce death and disability.

The Study Of Development Plan Based On The Analysis of the Import & Export Market In Korean Webtoon (한국웹툰의 수출입 시장분석을 통한 발전방안 연구)

  • Ryu, Yu-Hee;Lee, Seung-Jin
    • Cartoon and Animation Studies
    • /
    • s.42
    • /
    • pp.105-123
    • /
    • 2016
  • The webtoon market has been consisently developing in the digital market. Under such circumstances, The Korea webtoon market is rapidly growing and leading of them. This is the time to prepare the base of a stable environment for the webtoon market which shows a swift rise. The Korean webtoon is surely aiming at the global market as well as the domestic one. As the Korean webtoon companies spread out to the world briskly, The leading publication cartoon market, Japan tries to break into the Korean digital market. The domestic market that has the good-quality cartoons through exportation and importation to make people of all ages enjoy them. and also the Korean webtoon is in the center of the global webtoon markert. The early model of Korean webtoon, line-webtoon is translated in English, Chinese, Thai language and Indonesian language to use on the mobile applications and web. Nevertheless, It is just the stating point. With Eradicating of the Achilles heel of the digital contents, illegal distribution and finding materials for cultural discount rate minimized cartoon, The Korean webtoon can become the highest in the global market and hold it. Moreover, not only webtoon but also published cartoons are existing together to have a long run. Beyond the existing cartoon books printed on paper, we should reach toward the digital books with portability and economic feasibility to make the contents stay out longer.

Risk Factors for Recurrent Pneumothorax after Primary Spontaneous Pneumothorax (원발 기흉 수술 후 재발의 위험인자)

  • Yu, Jai-Kun;Lee, Seong-Ki;Seo, Hong-Joo;Seo, Min-Bum
    • Journal of Chest Surgery
    • /
    • v.41 no.6
    • /
    • pp.724-728
    • /
    • 2008
  • Background: The purpose of this study was to identify factors associated with recurrent pneumothorax after wedge resection in primary spontaneous pneumothorax in our hospital. Material and Method: Two hundred thirty-five consecutive patient (98% males; mean age, $23.9{\pm}4.5$ years) who had undergone video-assisted thoracoscopic surgery (VATS) were reviewed retrospectively. The two groups were divided as follows: group A, non-recurrent patients (225 patients [96%]); and group B, recurrent group (10 patients [4%]); the risk factors were compared between the two groups. The single and multiple factors that influenced the recurrence rate were analyzed using Cox's proportional hazard model. Result: There were no significant differences between the recurrent and non-recurrent groups in terms of gender, smoking, site of recurrence, degree of collapse, operative time, and number or weight of resected bullae. The recurrence rate was significantly more common in the following: younger ages, increased height/weight ratio, longer initial air leakage period, and shorter duration of chest drainage. Early aggressive exercise (<30 days) of patients after wedge resection increased the tendency for recurrence. Conclusion: Thoracoscopic wedge resection does not have a higher recurrence rate than open thoracotomy. However, young age, height/weight ratio, continuous air, and duration of chest tube placement were risk factors for a recurrent pneumothorax.

The Study on Optimal Image Processing and Identifying Threshold Values for Enhancing the Accuracy of Damage Information from Natural Disasters (자연재해 피해정보 산출의 정확도 향상을 위한 최적 영상처리 및 임계치 결정에 관한 연구)

  • Seo, Jung-Taek;Kim, Kye-Hyun
    • Spatial Information Research
    • /
    • v.19 no.5
    • /
    • pp.1-11
    • /
    • 2011
  • This study mainly focused on the method of accurately extracting damage information in the im agery change detection process using the constructed high resolution aerial im agery. Bongwha-gun in Gyungsangbuk-do which had been severely damaged from a localized torrential downpour at the end of July, 2008 was selected as study area. This study utilized aerial im agery having photographing scale of 30cm gray image of pre-disaster and 40cm color image of post-disaster. In order to correct errors from the differences of the image resolution of pre-/post-disaster and time series, the prelim inary phase of image processing techniques such as normalizing, contrast enhancement and equalizing were applied to reduce errors. The extent of the damage was calculated using one to one comparison of the intensity of each pixel of pre-/post-disaster im aged. In this step, threshold values which facilitate to extract the extent that damage investigator wants were applied by setting difference values of the intensity of pixel of pre-/post-disaster. The accuracy of optimal image processing and the result of threshold values were verified using the error matrix. The results of the study enabled the early exaction of the extents of the damages using the aerial imagery with identical characteristics. It was also possible to apply to various damage items for imagery change detection in case of utilizing multi-band im agery. Furthermore, more quantitative estimation of the dam ages would be possible with the use of numerous GIS layers such as land cover and cadastral maps.

Full-mouth rehabilitation in an amelogenesis imperfecta patient with anterior open bite using CAD/CAM system (전치부 개방교합을 보이는 법랑질형성부전증 환자의 CAD/CAM system을 이용한 전악 수복 증례)

  • Lee, Sang-Hoon;Yi, Yang-Jin;Jo, Deuk-Won
    • The Journal of Korean Academy of Prosthodontics
    • /
    • v.55 no.4
    • /
    • pp.410-418
    • /
    • 2017
  • Amelogenesis imperfecta characterized as abnormally formed enamel is caused by a defect of unique group of genes. Patients affected by this disease might have difficulties in social and psychological aspects due to non-esthetic teeth as well as functional problems caused by enamel detachment and tooth wear from their early ages. Adult patients with amelogenesis imperfecta can be treated with full-mouth restorations, which make functional and esthetic rehabilitations of severely worn tooth. However, the anterior open bite and lack of occlusal clearance for posterior teeth restorations due to compensatory extrusion are the intervening factors in the prosthetic treatment. Therefore, the determination of anterior tooth lengths, vertical dimension, and anterior guidance should be set carefully. Recently, computer-aided design and computer-aided manufacturing (CAD/CAM) techniques help systematic approaches and enable dentists to reduce time-consuming procedures in the diagnosis and treatment of full-mouth rehabilitation. This case report demonstrates the successful full mouth rehabilitation using a CAD/CAM system in a young adult patient with amelogenesis imperfecta and anterior open bite.

Strength Properties of Mortar Mixed with Accelerator for Freeze Protection in Constant and Variable Temperature Condition (정온 및 변온조건하에서 내한촉진제를 혼합한 모르터의 강도특성)

  • Kim, Young-Jin;Lee, Sang-Soo;Won, Cheol;Park, Sang-Joon
    • Journal of the Korea Concrete Institute
    • /
    • v.14 no.6
    • /
    • pp.942-948
    • /
    • 2002
  • When fresh concrete is exposed to low temperature, the concrete may suffer frost damage due to freezing at early ages and the strength development may be delayed. One of the solution methods to resolve these problems is to reduce freezing temperature of concrete by the use of chemical admixture called Accelerator for freeze protection. In this study we Investigate the effect on the strength development of cement mortar using accelerator for freeze protection with the variable curing condition. As the result of this study, the mortar using accelerator for freeze protection show continuously the strength development in curing condition of -5$^{\circ}C$. And the compressive strength under variable temperature condition was higher than constant temperature condition in same maturity.

A Study on the Carbonation Characteristics of Fly Ash Concrete by Accelerated Carbonation Test (급속 촉진 탄산화 시험을 통한 플라이애쉬 콘크리트의 탄산화 특성 연구)

  • Choi, Sung;Lee, Kwang-Myong;Jung, Sang-Hwa;Kim, Joo-Hyung
    • Journal of the Korea Concrete Institute
    • /
    • v.21 no.4
    • /
    • pp.449-455
    • /
    • 2009
  • The increase of industrial carbonic dioxide emissions has accelerated the carbonation of reinforced concrete structures, which drops off their durability. Although advanced countries have already taken safety control measures against the carbonation of RC structures, it is still difficult now to accurately predict the actual carbonation depth. Additionally, it requires much time and efforts. Recently, it is possible to get the data more rapidly through accelerated carbonation test with the $CO_2$ concentration of 100%. In this paper, the carbonation test results obtained by two test methods such as the normal carbonation test method and the accelerated carbonation test method, were compared to investigate the carbonation characteristics of fly ash concrete. The accelerated carbonation test on concrete specimens with the pre-curing age of 180 days was also carried out to examine the carbonation characteristics of fly ash concrete at long-term age. Consequently, fly ash concrete at early age was vulnerable to carbonation and however, its carbonation resistance at long-term ages was improved compared with OPC concrete.

Strength and Resistance to Chloride Penetration in Concrete Containing GGBFS with Ages (GGBFS를 혼입한 콘크리트의 재령에 따른 강도 및 염소이온 침투 저항성)

  • Park, Jae-Sung;Yoon, Yong-Sik;Kwon, Seung-Jun
    • Journal of the Korea Concrete Institute
    • /
    • v.29 no.3
    • /
    • pp.307-314
    • /
    • 2017
  • Concrete is a durable and cost-benefit construction material, however performance degradation occurs due to steel corrosion exposed to chloride attack. Penetration of chloride ion usually decreases due to hydrates formation and reduction of pores, and the reduced chloride behavior is considered through decreasing diffusion coefficient with time. In the work, HPC (High Performance Concrete) samples are prepared with 3 levels of W/B (water to binder) ratios of 0.37, 0.42, and 0.27 and 3 levels of replacement ratios of 0%, 30% and 50%. Several tests containing chloride diffusion coefficient, passed charge, and compressive strength are performed considering age effect of 28 days and 180 days. Chloride diffusion is more reduced in OPC concrete with lower W/B ratio and GGBFS concrete with 50% replacement ratio shows significant reduction of chloride diffusion in higher W/B ratio. At the age of 28 days, GGBFS concrete with 50% replacement ratio shows more rapid reduction of chloride diffusion than strength development, which reveals that abundant GGBFS replacement has effective resistance to chloride penetration even in the early-aged condition.