• Title/Summary/Keyword: eMP

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Studies on the Sedative Alkaloids from Zizyphus spinosus Semen

  • Han, Byung-Hoon;Park, Myung-Hwan;Park, Jeong-Hill
    • Korean Journal of Pharmacognosy
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    • v.16 no.4
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    • pp.233-238
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    • 1985
  • A number of sedative alkaloids were isolated from Sanjoin(酸棗仁), the seeds of Zizyphus vulgaris Lamark var. spinosus Bunge (Rhamnaceae) which is an important Chinese medicinal material used to treat insomnia and sometimes to treat sleepiness. Those compounds were designated as Sanjoinine-A, B, C, D, etc. depending on the order of increasing polarity. Sanjoinine-A, $C_{31}H_{42}N_4O_4$, $mp\;249^{\circ}$, $[{\alpha}]^{27}_D-316$, Sanjoinine-B, $C_{30}H_{40}N_4O_4$, $mp\;212{\sim}4^{\circ}$, Sanjoinene, $C_{29}H_{35}N_3O_4$, $mp\;281{\sim}2^{\circ}$, $[{\alpha}]^{22}_D-272$, Sanjoinine-D, $C_{32}H_{46}N_4O_5$, $mp\;256{\sim}8^{\circ}$, $[{\alpha}]^{22}_D-53.6$, Sanjoinine-F, $C_{31}H_{42}N_4O_5$, $mp\;228{\sim}9^{\circ}$, $[{\alpha}]^{22}_D-215$, and $Sanjoinine-G_1,\;C_{31}H_{44}N_4O_5,\;mp\;236{\sim}8^{\circ},\;[{\alpha}]^{22}_D-68.6$, were found as 14-membered cyclic peptide alkaloids, $Sanjoinine-G_2,\;C_{30}H_{42}N_4O_4,\;mp\;182^{\circ},\;[{\alpha}]^{22}_D-79.2$, as being open chain peptide alkaloid, and Sanjoinine-E, $C_{19}H_{21}NO_2$, $mp\;166^{\circ}$, $[{\alpha}]^{20}_D-146.2$, N-Methylasimilobine, $C_{18}H_{19}NO_2$, $mp\;193{\sim}5^{\circ}$, $[{\alpha}]^{20}_D-204$, Sanjoinine-Ia, $C_{18}H_{19}NO_2$, $mp\;155{\sim}7^{\circ}$, $[{\alpha}]^{20}_D-140$, Sanjoinine-Ib, $C_{19}H_{21}NO_4$, $mp\;184^{\circ}$, Sanjoinine-K, $C_{16}H_{19}NO_3$, $mp\;159{\sim}61^{\circ}$, $[{\alpha}]^{20}_D+35$, Caaverine, $C_{17}H_{17}NO_2$, $mp\;204^{\circ}$, $[{\alpha}]^{20}_D-80$, and Zizyphusine, $C_{20}H_{24}NO_4$, $mp\;214{\sim}6^{\circ}$, $[{\alpha}]^{20}_D+317$ as being aporphine alkaloids. The heat treatment of the cyclic peptide alkaloids produced their isomeric products which showed enhanced sedative activity. The chemical structure of the isomeric products will be discussed.

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Naturally Derived Probiotic Supplementation Effects on Physiological Properties and Manure Gas Emission of Broiler Chickens

  • Hassan, Md R.;Ryu, Kyeong-Sun
    • Journal of agriculture & life science
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    • v.46 no.4
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    • pp.119-127
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    • 2012
  • To investigate the influence of multi-probiotic, fermented ginseng byproduct and fermented sulfone on the performance, intestinal microflora and immunity of broiler, a five weeks trial was conducted with 340, 1-d-old $Ross{\times}Ross$ broiler. All broilers were divided into five different groups having 68 birds in each treatment, and they were assigned as control, antibiotic avilamycin (AB), multi-probiotic (MP), fermented sulfone (FS) and fermented ginseng byproduct (FGB). Each artificial or naturally derived probiotic was inoculated 0.1% level with the basal diet, and all diets were provided to birds for five weeks. Weight gain and feed intake were measured weekly basis, and blood, spleen and feces were collectedand used for the physiological properties of broiler chickens. All performances and cholesterol profiles were not significantly differed but numerically lower level of neutral fat and LDL was found in multi-probiotics and FGB treatments respectively. The salmonella spp and E. coli numbers in the ileum were high in control in relation to those of other treatments and were significantly decreased in antibiotics treatments (p<0.05). In addition, Lactobacillus spp. showed significantly higher proliferation in MP as compared to that of others (p<0.05). Fecal ammonia and $CO_2$ gas emission was significantly decreased in MP, FGB and FS, respectively (p<0.05), but significantly increased proliferation of spleen was determined in MP group in comparison of other treatments (p<0.05). Therefore, the results indicates that multi-probiotics would be valuable feed additives to improve the salmonella, E. coli and Lactobacillus proliferation, and manure gas emission of broiler chickens, but further study related to the production of manure gas emission of MP is necessary.

Spectral Efficiency Evaluation of Coordinated Multi-point Systems Based on System Level Simulations (멀티 포인트 시스템에서 시스템 레벨 시뮬레이션에 기반을 둔 스펙트럼 효율성 검증)

  • Jung, Bang-Chul;Shin, Won-Yong;Ban, Tae-Won
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.15 no.10
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    • pp.2113-2120
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    • 2011
  • In this paper, so as to improve spectral efficiency for cell-boundary users, we introduce a coordinated multi-point (CoMP) system, which is one of inter-cell cooperative transmission strategies studied in 3GPP long-term evolution-advanced (LTE-A) systems, and develop a system-level simulator to evaluate performance. To identify performance improvement of the system with inter-cell cooperative transmission, we select a 3GPP LTE system as a reference, which shows the highest performance among the existing mobile communication systems, and conduct a performance comparison. System-level simulation is performed based on widely-used OPNET tool. We implement modules including central unit (CU), CoMP eNodeB (CeNB), user equipment (UE), and multiple-input multiple-output (MIMO) channel model, while designing the inter-cell cooperative transmission system. Under WINNER wireless channel model and international telecommunication union (ITU) network model environments, we then evaluate the performance of edge users who belong to the lower 5% in terms of spectral efficiency. It is finally shown that throughput of the proposed CoMP system gets improved up to 2.5 times compared to that of the 3GPP LTE reference system.

Theoretical Investigation for the Molecular Structures and Dimerization Energies for Complexes of H2O-C6H6 Dimer (물(H2O)과 벤젠(C6H6) 이합체의 분자 구조 및 결합 에너지에 관한 이론 연구)

  • Sun, Ju-Yong;Kim, Seung-Joon
    • Journal of the Korean Chemical Society
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    • v.53 no.1
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    • pp.7-16
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    • 2009
  • The global minimum structures of the benzene-water, Bz-$H_2O$ and benzene-water cation complex, [Bz-$H_2O]^+$ have been investigated using ab initio and density functional theory(DFT) with very large basis sets. The highest levels of theory employed in this study are B3LYP/cc-pVQZ for geometry optimization and MP2/aug-cc-pVTZ//B3LYP/aug-cc-pVTZ for binding energy. The harmonic vibrational frequencies and IR intensities are also determined at the various levels of theory to confirm whether the structure of water complex is affected by the presence of benzene. The binding energies of Bz-$H_2O$ (N-1) structure are predicted to be 3.92 kcal/mol ($D_e$) and 3.11 kcal/mol ($D_0$) after the zero-point vibrational energy correction at the MP2/cc-pVQZ//B3LYP/cc-pVQZ level of theory. The binding energies of [Bz-$H_2O]^+$ (C-1) structure are predicted to be 9.06 kcal/mol for $D_e$ and 7.82 kcal/mol for $D_0$ at the same level of theory.

Extraction of Water-Soluble Porphyrin and Metalloporphyrins into Acetonitrile by Salting-out

  • Tabata, Masaaki;Kumamoto, Midori
    • Analytical Science and Technology
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    • v.8 no.4
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    • pp.511-517
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    • 1995
  • A cationic water soluble porphyrin (5,10,15,20-tetrakis (l-methyl-pyridinium-4-yl)porphyrin, $H_2tmpyp^{4+}$) and its metalloporphyrins (MP) were easily extracted into acetonitrile separated by addition of sodium chloride ($4mol\;dm^{-3}$) in the presence of sodium perchlorate, where M denotes $Zn^{2+}$, $Cu^{2+}$, $Co^{3+}$, $Fe^{3+}$, and $Mn^{3+}$ and $P^{2-}$ is porphyrinate ion. The extracted ion-pair complexes were completely dissociated to $[MP(ClO_4)_3]^+$, and $[MP(ClO_4)_2]^{2+}$. The extraction and the dissociation constants were determined by taking into account of the partition constant of sodium perchlorate ($K_D=1.82{\pm}0.01$). The chemical properties of the separated acetonitrile phase as $E_{T(30)}$ and $D_{II,I}$ were determined and compared with other water miscible solvents (acetone, actonitrile, 1,4-dioxane, tetrahydrofuran, 1-propanol and 2-propanol). Furthermore, a sensitive and selective method was proposed for the determination of a subnanogram amount of copper(II) in natural water samples by using the present salting-out method and the porphyrins.

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VDI Performance Optimization with Hybrid Parallel Processing in Thick Client System under Heterogeneous Multi-Core Environment (Heterogeneous 멀티 코어 환경의 Thick Client에서 VDI 성능 최적화를 위한 혼합 병렬 처리 기법 연구)

  • Kim, Myeong-Seob;Huh, Eui-Nam
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.38B no.3
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    • pp.163-171
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    • 2013
  • Recently, the requirement of processing High Definition (HD) video or 3D application on low, mobile devices has been expanded and content data has been increased as well. It is becoming a major issue in Cloud computing where a Virtual Desktop Infrastructure (VDI) Service needs efficient data processing ability to provide Quality of Experience (QoE) in Cloud computing. In this paper, we propose three kind of Thick-Thin VDI Service which can share and delegate VDI service based on Thick Client using CPU and GPU. Furthermore, we propose and discuss the VDI Service Optimization Method in mixed CPU and GPU Heterogeneous Environment using CPU Parallel Processing OpenMP and GPU Parallel Processing CUDA.

Resource allocation algorithm for multiuser MIMO-OFDMA systems with CoMP (CoMP 기법이 적용된 다중 사용자 MIMO-OFDMA 시스템을 위한 자원 할당 기법)

  • Choi, Dongwook;Lee, Jae Hong;Lee, Moon-Sik;Kim, Ilgyu
    • Proceedings of the Korean Society of Broadcast Engineers Conference
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    • 2010.11a
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    • pp.225-228
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    • 2010
  • 본 논문은 CoMP 기법이 적용된 다중 사용자 MIMO-OFDMA 시스템을 위한 자원할당 알고리즘을 제안한다. 제안된 알고리즘에서는 eNode B가 RRE와 UE간의 채널 정보를 이용하여 전체 송신 전력 제한을 가지면서 전체 데이터 레이트가 최대가 되도록 자원을 할당한다. 자원할당 알고리즘을 통해 얻어진 결과를 이용하여 부반송파에 다수의 UE들이 할당된다. 할당된 UE들은 각각 MIMO 채널을 통해 다수의 공간경로를 갖고 각 공간경로에서는 할당된 전력에 따라 QPSK, 16QAM, 64QAM 중 하나를 선택하여 전송한다.

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Design of AOD System based on PKI for e-Commerce (전자상거래를 위한 공개키 기반 AOD 시스템의 설계)

  • 김영준;이윤정;박남섭;이병래;김태윤
    • Proceedings of the Korean Information Science Society Conference
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    • 2001.10a
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    • pp.658-660
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    • 2001
  • 최근 초고속 통신망을 이용한 인터넷의 대중화와 더불어 인터넷을 기반으로 하는 전자상거래가 활발해지고 있다. 특히 인터넷을 통한MP3 데이터 등의 멀티미디어 컨텐츠의 유통은 많은 연구의 대상이 되고 있다. 하지만 기존의 AOD(Audio On Demand) 시스템들은 실질 적인 불법복제방지와 저작권 보호에 미흡한 단점이 있다. 따라서 본 논문에서는 공개키 기반 구조(PKI: Public Key Infrastructure)[1,2]에 기초하여 실질적인 불법복제방지와 저작권을 보호하는 AOD 시스템을 제안한다. 제안된 기법은 사용자의 공개키를 이용하여 MP3 데 이터를 전송함으로써 전송 도중 제 3자로부터의 공격에 대응할 수 있고, 정당한사용자 외에는 MP3 데이터를 사용하지 못하도록 함으로써 사용자와 판매자의 권리를 보장한다.

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Microplastic pollution in two industrial locations of the Karnaphuli River, Bangladesh: insights on abundance, types, and characteristics

  • Shahida Arfine Shimul;Zannatul Bakeya;Jannatun Naeem Ananna;Antar Sarker;Saifuddin Rana;Sk. Ahmad Al Nahid
    • Fisheries and Aquatic Sciences
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    • v.26 no.12
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    • pp.715-725
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    • 2023
  • Microplastic (MP) pollution in aquatic environments is a growing concern worldwide. This study investigated the abundance, types, and attributes of MPs in the surface water at two industrial sites (Avoimitro Ghat and Kalurghat) along the Karnaphuli River in Chattogram, Bangladesh. Sampling was conducted over eight months across three transects encompassing a total area of 500 m at each site. A manta net of 200 ㎛ mesh size was used to sample MPs. The obtained samples were subsequently filtered, enumerated, and characterized using a stereo microscope and imaging software. The mean abundance of MP particles (per km2 ) was found higher in Avoimitro Ghat (94,861 ± 57,126) than in Kalurghat (31,343 ± 23,183). A significant statistical difference (p < 0.05) was observed in the mean abundance of MP particles between the wet and dry seasons. The fragment group of MP exhibited the most abundant category, whereas the pellet category displayed the lowest. MPs with an elongated shape prevailed at both locations throughout all seasons. At Avoimitro Ghat, blue-colored MPs demonstrated the highest mean count, while in Kalurghat, the highest mean count belonged to brown-colored MPs. The size distribution of MPs differed between the two sites, with 1-2 mm MPs being plentiful in both seasons and Avoimitro Ghat, whereas MPs ranging from 500 ㎛ to less than 1 mm were abundant in Kalurghat. Ten (10) polymer types were found from Fourier-transform infrared spectroscopy (FTIR) analysis with high levels of polypropylene atactic in both Avoimitro Ghat (32%) and Kalurghat (17%). The findings provide important insights into MP pollution in the Karnaphuli River, which may aid in developing effective strategies to mitigate the impacts of MP pollution on the aquatic ecosystem and human health.

Influence of the pH and Salt Concentrations on Physicochemical Properties of Pork Myofibrillar Protein Gels Added with Cornstarch

  • Lee, Chang Hoon;Chin, Koo Bok
    • Food Science of Animal Resources
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    • v.40 no.2
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    • pp.254-261
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    • 2020
  • The aim of this study was to evaluate quality characteristics of pork myofibrillar protein (MP) added with cornstarch as affected by different pH values and salt cocnentrations. MP mixtures were prepared with three different pH values (pH 6.00, 6.25, and 6.50) and three different salt concentrations (0.15, 0.30, and 0.45 M). Cooking yield (CY), gel strength, viscosity, and scanning electron microscopy were measured to evaluate characteristics of MPs. CYs of MPs with cornstarch at above pH 6.25 or salt 0.30 M were increased compared to those at pH 6.00 or salt 0.15 M. However, gel strengths of MPs at salt 0.45 M were higher than those at salt 0.30 M. In microstructure analysis, MP gels with increasing pH value and salt concentration showed compact and uniform structure. Thus, MP gels with pH 6.25 and salt concentration of 0.30 M would be better for manufacturing meat products containing cornstarch to increase their water holding ability.