• Title/Summary/Keyword: e-pedigree

Search Result 37, Processing Time 0.027 seconds

Design & Implementation of Drug Management System based on RFID (RFID기반의 특수의약품 추적관리 시스템 설계 및 구현)

  • Lee, Bong-Keun
    • The KIPS Transactions:PartD
    • /
    • v.13D no.7 s.110
    • /
    • pp.977-984
    • /
    • 2006
  • This paper is intended to trace and management of drug based on RFID Technology at a circulation market, from manufacturer to end user, of drug. To avoid counterfeit and generic drug and establish of order in the circulation of drug, at the moment of manufacturing, tags for each bottle and each box are tagged. and then from factory to hospital, through whole logistics, e-pedigree for the drug is made and monitored. Using inventory information, it is easy to manage and control stock of drug. In addition to, RFID System enables storing and delivery to be simple, process time to be shortened. As this research is to study of applying RFID to drug, in this paper, standard RFID code for drug is suggested and tried to apply domestic middle win. Finally, the result of tag pattern design and how to tag for the drug based on 90Mhz is proposed

Population genetic structure analysis and effect of inbreeding on body weights at different ages in Iranian Mehraban sheep

  • Yavarifard, Roya;Hossein-Zadeh, Navid Ghavi;Shadparvar, Abdol Ahad
    • Journal of Animal Science and Technology
    • /
    • v.56 no.8
    • /
    • pp.31.1-31.9
    • /
    • 2014
  • The objective of this study was to describe the population structure and inbreeding, and to quantify their effects on weights at different ages of Mehraban sheep in Iran. The analysis was based on the pedigree information of 26990 animals and 10278 body weight records from birth to yearling age. Data and pedigree information were collected during 1994 to 2011 by the breeding station of Mehraban sheep. The population structure was analyzed using the CFC program. Inbreeding of all animals was calculated by INBUPGF90 program. All animals were grouped into three classes according to their inbreeding coefficients: the first class included non-inbred animals (F=0); and the second and third classes included inbred animals (0$F{\geq}0.05$, respectively). The average inbreeding in Mehraban sheep was 1.69%. Founder equivalent ($f_e$) values were estimated to be 4244, 3116 and 2965 during 1994-1999, 2000-2005 and 2006-2011, respectively. The effective population sizes ($N_e$) were 363, 5080 and 5740 during 1994-1999, 2000-2005 and 2006-2011, respectively. Generation interval was 2.15 years for this breed of sheep. Regression coefficients of birth weight, 3-month weight, 6-month weight and yearling weight on lamb inbreeding were estimated to be -6.340.69, -14.685.33, 48.009.43 and 98.6515.65, respectively. Both positive and negative inbreeding effects were found in the current study. The utilization of a program for designed mating system, in the present flock, could be a suitable approach to keep the level of inbreeding under control.

A New Color Grafted Cactus (Copiapoa scopa) Cultivar "Red Stone" (접목선인장 코피아포아 신품종 "레드스톤" 육성)

  • Cho, Chang-Hui;Nam, Sang-Yong;Lee, Sang-Deok;Park, Young-Su
    • Korean Journal of Breeding Science
    • /
    • v.40 no.4
    • /
    • pp.525-528
    • /
    • 2008
  • A new graft cactus (Copiapoa scopa) cultivar 'Redstone' was developed at Cactus Research Institute, Gyeonggi-do A.R.E.S, in 2007. GCP563 and GCP618 were crossed in 2004 and we got 9 seedlings from this combination. After pedigree selection in 2005, one cultivar was finally selected through the test of specific character in 2007 and named as "Redstone". "Redstone" cultivar has red brown color and round globose shape with 15 ribs and its spines are black. This cultivar is able to produce 26.8 offshoots per plant. 'Redstone' cultivar has higher productivity and more slow growth than Copiapoa scopa cultivar.

A New Yellow Color Grafted Cactus (Chamaecereus silvestrii) Cultivar "Yellow Tree" (접목선인장 황색계 산취 신품종 "옐로우트리" 육성)

  • Cho, Chang-Hui;Nam, Sang-Yong;Lee, Sang-Deok;Park, Heung-Bae
    • Korean Journal of Breeding Science
    • /
    • v.40 no.4
    • /
    • pp.521-524
    • /
    • 2008
  • A new graft cactus (Chamaecereus silvestrii f. variegata) cultivars "Yellow Ttree" was developed at Cactus Research Institute, Gyeonggi-do A.R.E.S. in 2007. GC013001 and GC0110703 were crossed in 2005 and we got 42 seedlings from this combination. After pedigree selection in 2005, one cultivar were finally selected through the test of specific character in 2007 and named as "Yellow Ttree". "Yellow Ttree" has cylindrical shape of yellow color with 13~14 ribs. Formation of its offshoots is concentrated on the lower part of the plant. This cultivar is able to produce 13.9 offsets shoots per plant and its offshoots are hard.

Genetic diversity evolution in the Mexican Charolais cattle population

  • Rios-Utrera, Angel;Montano-Bermudez, Moises;Vega-Murillo, Vicente Eliezer;Martinez-Velazquez, Guillermo;Baeza-Rodriguez, Juan Jose;Roman-Ponce, Sergio Ivan
    • Animal Bioscience
    • /
    • v.34 no.7
    • /
    • pp.1116-1122
    • /
    • 2021
  • Objective: The aim was to characterize the genetic diversity evolution of the registered Mexican Charolais cattle population by pedigree analysis. Methods: Data consisted of 331,390 pedigree records of animals born from 1934 to 2018. Average complete generation equivalent, generation interval, effective population size (Ne), and effective numbers of founders (fe), ancestors (fa), and founder genomes (Ng) were calculated for seven five-year periods. The inbreeding coefficient was calculated per year of birth, from 1984 to 2018, whereas the gene contribution of the most influential ancestors was calculated for the latter period. Results: Average complete generation equivalent consistently increased across periods, from 4.76, for the first period (1984 through 1988), to 7.86, for the last period (2014 through 2018). The inbreeding coefficient showed a relative steadiness across the last seventeen years, oscillating from 0.0110 to 0.0145. During the last period, the average generation interval for the father-offspring pathways was nearly 1 yr. longer than that of the mother-offspring pathways. The effective population size increased steadily since 1984 (105.0) and until 2013 (237.1), but showed a minor decline from 2013 to 2018 (233.2). The population displayed an increase in the fa since 1984 and until 2008; however, showed a small decrease during the last decade. The effective number of founder genomes increased from 1984 to 2003, but revealed loss of genetic variability during the last fifteen years (from 136.4 to 127.7). The fa:fe ratio suggests that the genetic diversity loss was partially caused by formation of genetic bottlenecks in the pedigree; in addition, the Ng:fa ratio indicates loss of founder alleles due to genetic drift. The most influential ancestor explained 1.8% of the total genetic variability in the progeny born from 2014 to 2018. Conclusion: Inbreeding, Ne, fa, and Ng are rather beyond critical levels; therefore, the current genetic status of the population is not at risk.

Validation of selection accuracy for the total number of piglets born in Landrace pigs using genomic selection

  • Oh, Jae-Don;Na, Chong-Sam;Park, Kyung-Do
    • Asian-Australasian Journal of Animal Sciences
    • /
    • v.30 no.2
    • /
    • pp.149-153
    • /
    • 2017
  • Objective: This study was to determine the relationship between estimated breeding value and phenotype information after farrowing when juvenile selection was made in candidate pigs without phenotype information. Methods: After collecting phenotypic and genomic information for the total number of piglets born by Landrace pigs, selection accuracy between genomic breeding value estimates using genomic information and breeding value estimates of best linear unbiased prediction (BLUP) using conventional pedigree information were compared. Results: Genetic standard deviation (${\sigma}_a$) for the total number of piglets born was 0.91. Since the total number of piglets born for candidate pigs was unknown, the accuracy of the breeding value estimated from pedigree information was 0.080. When genomic information was used, the accuracy of the breeding value was 0.216. Assuming that the replacement rate of sows per year is 100% and generation interval is 1 year, genetic gain per year is 0.346 head when genomic information is used. It is 0.128 when BLUP is used. Conclusion: Genetic gain estimated from single step best linear unbiased prediction (ssBLUP) method is by 2.7 times higher than that the one estimated from BLUP method, i.e., 270% more improvement in efficiency.

Development of EST-SSRs and Assessment of Genetic Diversity in Germplasm of the Finger Millet, Eleusine coracana (L.) Gaertn.

  • Wang, Xiaohan;Lee, Myung Chul;Choi, Yu-Mi;Kim, Seong-Hoon;Han, Seahee;Desta, Kebede Taye;Yoon, Hye-myeong;Lee, Yoonjung;Oh, Miae;Yi, Jung Yoon;Shin, Myoung-Jae;Kim, Kyung-Min
    • KOREAN JOURNAL OF CROP SCIENCE
    • /
    • v.66 no.4
    • /
    • pp.443-451
    • /
    • 2021
  • Finger millet (Eleusine coracana) is widely cultivated in tropical regions worldwide owing to its high nutritional value. Finger millet is more tolerant against biotic and abiotic stresses such as pests, drought, and salt than other millet crops; therefore, it was proposed as a candidate crop to adapt to climate change in Korea. In 2019, we used expressed sequence tag simple sequence repeat (EST-SSR) markers to evaluate the genetic diversity and structure of 102 finger millet accessions from two geographical regions (Africa and South Asia) to identify appropriate accessions and enhance crop diversity in Korea. In total, 40 primers produced 116 alleles, ranging in size from 135 to 457 bp, with a mean polymorphism information content (PIC) of 0.18225. Polymorphism was detected among the 40 primers, and 13 primers were found to have PIC values > 0.3. Principal coordinate and phylogenetic analyses, based on the combined data of both markers, grouped the finger millet accessions according to their respective collection areas.Therefore, the 102 accessions were classified into two groups, one from Asia and the other from Africa. We have conducted an in-depth study on the finger millet landrace pedigree. By sorting out and using the molecular characteristics of each pedigree, it will be useful for the management and accession identification of the plant resource. The novel SSR markers developed in this study will aid in future genetic analyses of E. coracana.

Estimation of Effective Population Size in the Sapsaree: A Korean Native Dog (Canis familiaris)

  • Alam, M.;Han, K.I.;Lee, D.H.;Ha, J.H.;Kim, J.J.
    • Asian-Australasian Journal of Animal Sciences
    • /
    • v.25 no.8
    • /
    • pp.1063-1072
    • /
    • 2012
  • Effective population size ($N_e$) is an important measure to understand population structure and genetic variability in animal species. The objective of this study was to estimate $N_e$ in Sapsaree dogs using the information of rate of inbreeding and genomic data that were obtained from pedigree and the Illumina CanineSNP20 (20K) and CanineHD (170K) beadchips, respectively. Three SNP panels, i.e. Sap134 (20K), Sap60 (170K), and Sap183 (the combined panel from the 20K and 170K), were used to genotype 134, 60, and 183 animal samples, respectively. The $N_e$ estimates based on inbreeding rate ranged from 16 to 51 about five to 13 generations ago. With the use of SNP genotypes, two methods were applied for $N_e$ estimation, i.e. pair-wise $r^2$ values using a simple expectation of distance and $r^2$ values under a non-linear regression with respective distances assuming a finite population size. The average pair-wise $N_e$ estimates across generations using the pairs of SNPs that were located within 5 Mb in the Sap134, Sap60, and Sap183 panels, were 1,486, 1,025 and 1,293, respectively. Under the non-linear regression method, the average $N_e$ estimates were 1,601, 528, and 1,129 for the respective panels. Also, the point estimates of past $N_e$ at 5, 20, and 50 generations ago ranged between 64 to 75, 245 to 286, and 573 to 646, respectively, indicating a significant $N_e$ reduction in the last several generations. These results suggest a strong necessity for minimizing inbreeding through the application of genomic selection or other breeding strategies to increase $N_e$, so as to maintain genetic variation and to avoid future bottlenecks in the Sapsaree population.

Inbreeding levels and effective population size of duroc populations of major swine breeding farms in Korea (국내 두록 품종의 근교수준 및 유효집단 크기 추정)

  • Hong, Joon Ki;Song, Na Rae;Kim, Du Wan;Kim, Si Dong;Kim, Young Hwa;Choi, Jae Gwan;Mun, Hyo Sik;Cho, Kyu Ho
    • Korean Journal of Agricultural Science
    • /
    • v.41 no.1
    • /
    • pp.41-46
    • /
    • 2014
  • The pedigree data of 86,639 heads from six major swine breeding farms were investigated to check levels of inbreeding and effective population size of breeding stocks. The average rate of inbreeding was 1.04%, 0.87%, 3.17%, 1.05%, 3.23% and 3.33% for farms A, B, C, D, E and F, respectively. The average inbreeding rate was highest for F farm and lowest for B farm. In farms D and E, there were quite large numbers of immigrant animals per generation compared to other farms. The effective population sizes calculated from the average rate of inbreeding were distributed between 83.0 and 814.8. Specific values were 282.3, 225.5, 83.0, 814.8, 302.9 and 175.7 for farms A, B, C, D, E and F, respectively. The results showed that there was no cause for concern over the current inbreeding level of major swine breeding farm populations and the inbreeding level was within an acceptable range. In addition, internal sharing rather than importing pig is necessary to strengthen seed sovereignty.

A New Euphorbia Cultivar 'Panorama' with Green and Pink Colored Bract (녹색과 분홍색의 포를 가진 다육식물 꽃기린 신품종 '파노라마' 육성)

  • Park, Heung-Bae;Nam, Sang-Yong;Chung, Jae-Woon;Lee, Jung-Jin;Park, In-Tae
    • Korean Journal of Breeding Science
    • /
    • v.42 no.6
    • /
    • pp.717-720
    • /
    • 2010
  • A new cultivar of Euphorbia milii, 'Panorama' was developed at Cactus Research Institute, Gyeonggi-do Agricultural Research & Extension Services in 2009. 'Gabi' and 'Maxi' were crossed in 2001 and three $F_1$ seedlings were obtained. Pedigree selection was performed in 2002. One line was finally selected and named as 'Panorama' through the test of specific character from 2007 to 2009. The new cultivar 'Panorama' has green and pink colored bract, and it has 2~3 each of inflorescence number, 2.0 cm of bract width, 4.3 each of lateral shoot and 14.9 cm of plant height. Characters of the cultivar can be maintained by vegetative propagation.