• Title/Summary/Keyword: e-clinical data

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Rehmanniae Radix, an Effective Treatment for Patients with Various Inflammatory and Metabolic Diseases: Results from a Review of Korean Publications

  • Kim, Seok-hee;Yook, Tae-han;Kim, Jong-uk
    • Journal of Pharmacopuncture
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    • v.20 no.2
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    • pp.81-88
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    • 2017
  • Objectives: This study was a review of the literature published on the efficacy of Rehmanniae Radix to obtain information to provide both a foundation for its clinical use and directions for future studies. Methods: This study selected 30 publications registered to databases or published in Korea by March 13, 2017, by searching electronic journal databases, i.e., NDSL, OASIS, RISS, and KISS, in order to review the efficacy of Rehmanniae Radix. The search was conducted using the keywords '生地黃', '鮮地黃', 'Rehmannia Glutinosa', and 'Rehmanniae Radix', and the search results were compiled and analyzed. Results: The selected publications included antioxidant effects (12 publications), data involving blood glucose reduction (4 publications), effects on the autonomic nervous system (3 publications), and effects on the human body (11 publications). Conclusion:The results of this literature review indicate that Rehmanniae Radix is effective in treating patients with various inflammatory and metabolic diseases, such as high blood pressure and diabetes. Based on these results, we believe that Rehmanniae Radix can be used effectively to treat patients with such diseases.

Surgical Repair of Partial Atrioventricular Canal Defect (부분심내막상 결손증의 교정수술치험 3례)

  • Kim, Yeong-Ho;Kim, Gong-Su
    • Journal of Chest Surgery
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    • v.18 no.2
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    • pp.299-304
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    • 1985
  • The partial A-V canal defect consist of ostium primum type atrial septal defect with a cleft mitral anterior leaflet. The clinical findings depend upon the site and size of the left-to-right shunt, the degree of A-V valvular regurgitation, and the degree of resultant pulmonary artery hypertension. We experienced 3 cases of similar condition. The data were as follow: 1. Chest P-A showed increased pulmonary vascularity and moderate cardiomegaly with left atrial enlargement. 2. E.K.G. showed left axis deviation, left atrial enlargement, and left ventricular hypertrophy. 3. Right heart catheterization showed significant 02 step up of SVC-RA and left-to-right shunt. 4. Left ventriculogram showed mitral regurgitation and filling of both atrium. Operative findings were as follow: 1. Primum type atrial septal defect [2x2 cm]. 2. Cleft in the anterior leaflet of the mitral vave. 3. No evidence of ventricular septal defect and tricuspid anomaly. Through a right atriotomy with moderate hypothermia, the mitral cleft was approximated with interrupted sutures. The interatrial communication was closed by a patch of Dacron/pericardium. The patch was attached to junction of the mitral and tricuspid valves along the crest of the ventricular septum using interrupted sutures and the other site using continuous sutures. Postoperative course was uneventful and discharged in good general condition except postoperative bleeding in case 3.

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The Determinants of the Quality of Life and Pain of Back Pain Patients (척추질환 환자의 삶의 질과 통증에 영향을 미치는 요인)

  • Lee, Jin-Gyu;Jin, Ki-Mam
    • Journal of Preventive Medicine and Public Health
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    • v.43 no.6
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    • pp.505-512
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    • 2010
  • Objectives: Because of the changing life style of Koreans, we have witnessed an increase of patients with back pain. The development of medical knowledge and technology has resulted in more numerous and better treatment methods. However, the outcomes of diverse treatments have been examined by using a few medicine-oriented measures like pain. This study aims at identifying the factors that influence the outcomes of back pain treatments by using two outcome measures (e.g., quality of life and pain). Methods: We used the questionnaire survey method for data collection. The questionnaires contained 5 categories (treatment methods, clinical conditions, exercise, quality of life and, socio-demographic characteristics). We interviewed 188 back pain patients. We used the regression analysis method to predict the quality of life or pain. Results: Surgery showed a statistically significant effect on the quality of life as well as pain. The illness period, age and exercise were turned out to be significant factors for both of the dependent variables. The social class and surgery methods showed a statistically significant effect solely on the quality of life. Conclusions: In choosing the surgical methods, doctors need to provide detailed explanations on the quality of life outcomes for each of the surgical methods to the patients.

AUTOMATIC DETECTION OF EPILEPTIFORM ACTIVITY USING WAVELET AND ARTIFICIAL NEURAL NETWORK (웨이브렛과 신경회로망을 이용한 간질 파형 자동 검출)

  • Park, H.S.;Park, C.H.;Lee, Y.H.;Lee, D.S.;Kim, S.I.
    • Proceedings of the KOSOMBE Conference
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    • v.1997 no.05
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    • pp.358-361
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    • 1997
  • This paper describes a multichannel epileptic seizure detection algorithm based on wavelet transform(WT), artificial neural network(ANN) and expert system. First, through the WT, a small number of wavelet coefficients is used to represent the single channel epileptic spike. Next, 3-layer feed-forward network employing the error back propagation algorithm is trained and tested using parameters obtained above. Finally, 16 channel expert system which is based on clinical experience is introduced as a artifact rejection and reliable detection. The suggested algorithm was implemented on personal computer(PC). Two main events i.e., epileptiform and normal activities, were selected from 32 person's EEGs(normal: 20, seizure disorder: 12) in consensus among experts. The result was that WT reduced data input size and ANN detected 97 of the 100 EEGs containing definite spike - sensitivity of 97%. Expert rule system was capable of rejecting a wide variety of artifacts commonly found in EEG recordings. It also reduced false positive detections of ANN.

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Influence of Nurse Manager and Peer Group Caring Behaviors as Perceived by Nurses on Intention to Retention (간호사가 지각하는 간호관리자의 돌봄-배려행위와 동료 간 돌봄-배려행위가 재직의도에 미치는 영향)

  • Kong, Moon Yeon;Kim, Jeong-Hee
    • Journal of Korean Academy of Nursing Administration
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    • v.23 no.2
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    • pp.191-200
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    • 2017
  • Purpose: This study was conducted to identify the influence of nurse manager and peer group caring behaviors as perceived by nurses on intention to retention. Methods: The participants for this study were 229 nurses who had worked for over 6 months in general hospitals located in J province. Survey data were analyzed descriptive statistics and t-tests, ANOVAs with $Scheff{\acute{e}}^{\prime}s$ post-hoc testing, Pearson's correlation coefficients, and hierarchical regression analysis. Results: The scores for 'manager and peer group caring behaviors' and intention to retention were all at a moderate level, although the subjects perceived 'peer group caring behaviors' as higher compared to 'manager caring behaviors'. There were significant differences in 'manager caring behaviors' scores by suitability for present working department and employment status and in 'peer group caring behaviors' scores by suitability for present working department. The factors influencing nurses' intention to retention were religion, suitability for present department, clinical experience of over ten years, 'manager caring behaviors', and 'peer group caring behaviors' Conclusion: To improve nurses' intention to retention, it may be necessary to alter the transfer and arrangement strategies of their working environments to better consider nurses' aptitude and competence, and thereby increase both manager and peer group caring behaviors.

Good Nursing Experience of Patients with Cancer in a Korean Cancer Hospital (암 병원 입원 환자들의 '좋은 간호(Good Nursing)' 경험)

  • Suh, Eunyoung E.;Yoo, Hye Jin;Hong, Jeong Hee;Kwon, In Gak;Song, Hyunju
    • Journal of Korean Critical Care Nursing
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    • v.13 no.3
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    • pp.51-61
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    • 2020
  • Purpose : This study aimed to explore and describe good nursing experiences of patients with cancer. Methods : Data were collected using individual in-depth interviews with 15 males and 8 females who were hospitalized in a Korean cancer hospital. The transcribed script was analyzed using Colaizzi's phenomenological method. Results : As a result, three theme clusters and nine themes were identified. The three theme clusters were as follows: "being kind and expert in every step along the cancer care trajectory," "taking an omnipotent mediator role supporting patients' well-being," and "providing professional care touching patients' mind and body." Three themes were assigned to each cluster to illustrate the given phenomena. Conclusion : Cancer patients wanted considerate understanding and sincere care from nurses while they experienced physical and emotional suffering owing to the cancer, treatment trajectory, and hospital system. To improve the quality of nursing care for cancer patients, patient-centered care combined with nurses' expertise in oncology care must be provided based on the insights from our study's findings.

The Effect of Glove Changing during Surgery for Colon Cancer (대장암수술 시 장갑교환의 효과)

  • Park, Eunji;Ham, Eunmi
    • Korean Journal of Adult Nursing
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    • v.26 no.1
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    • pp.98-106
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    • 2014
  • Purpose: The purpose of this study was to explore the effect of glove changing during surgery for colon cancer on reducing the degree of contamination of surgical gloves. Methods: The randomized posttest control group design was used. Total 72 surgeries of colon cancer in the K University Hospital in Seoul performed by the team of A-Surgeon and B-Scrub nurse were randomly assigned to one of the three groups. Glove changing with single-gloved state was implemented in the Experimental Group I and outer glove changing with double-gloved state was executed in the Experimental Group II. Single-gloved state was carried in the Control Group. Following the surgical procedure, specimens for bacterial culture were collected the from scrub nurse's gloves to compare the degree of contamination among the three groups. Data were analyzed with One-way ANOVA and the Scheff$\acute{e}$'s multiple comparison test. Results: The degrees of contamination of the Experimental Group I and II were significantly lower than that of the Control Group. There was no significant difference between Experimental Group I and II. Conclusion: Glove changing during surgery with either single or double-gloved state is effective in reducing the degree of contamination of surgical gloves, therefore these methods should be utilized in clinical practice.

Factors Affecting Core Competencies among Infection Control Nurses in Korea (국내 감염관리간호사의 핵심역량과 영향요인 분석)

  • Kim, Kyung Mi;Choi, Jeong Sil
    • Korean Journal of Adult Nursing
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    • v.26 no.1
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    • pp.11-21
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    • 2014
  • Purpose: This study was conducted to describe core competencies and identify factors affecting core competencies among infection control nurses (ICN). Methods: Infection control nurses from hospital with more than 200 beds comprised the sample. Questionnaires were sent to the sample via e-mail. One hundred and three questionnaires were returned. Data were analyzed with descriptive statistics and stepwise multiple regression via SPSS/WIN 21.0. Results: The core competency level of healthcare workers area was the highest that of the education and research was the lowest. There were significant differences in core competencies related to demographics such as age, clinical carrier, infection control carrier, position, academic degree, infection control specialist license, hospital location, and hospital type. The explained variances for the core competency were 38.3% and the contributing factors to core competencies were infection control carrier and infection control specialist license. Conclusion: It showed various levels of core competencies depending on infection control nurses' demographics and hospital traits, therefore consistent management efforts for the licensing and career path of infection control would be required.

PPARγ Physiology and Pathology in Gastrointestinal Epithelial Cells

  • Thompson, E. Aubrey
    • Molecules and Cells
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    • v.24 no.2
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    • pp.167-176
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    • 2007
  • Peroxisome proliferator-activated receptor-gamma ($PPAR{\gamma}$) is expressed at very high levels in the gastrointestinal epithelium. Many of the functions of $PPAR{\gamma}$ in gastrointestinal epithelial cells have been elucidated in recent years, and a pattern is emerging which suggests that this receptor plays an important role in gastrointestinal physiology. There is also strong evidence that $PPAR{\gamma}$ is a colon cancer suppressor in pre-clinical rodent models of sporadic colon cancer, and there is considerable interest in exploitation of $PPAR{\gamma}$ agonists as prophylactic or chemopreventive agents in colon cancer. Studies in mice and in human colon cancer cell lines suggest several mechanisms that might account for the tumor suppressive effects of $PPAR{\gamma}$ agonists, although it is not in all cases clear whether these effects are altogether mediated by $PPAR{\gamma}$. Conversely, several reports suggest that $PPAR{\gamma}$ agonists may promote colon cancer under certain circumstances. This possibility warrants considerable attention since several million individuals with type II diabetes are currently taking $PPAR{\gamma}$ agonists. This review will focus on recent data related to four critical questions: what is the physiological function of $PPAR{\gamma}$ in gastrointestinal epithelial cells; how does $PPAR{\gamma}$ suppress colon carcinogenesis; is $PPAR{\gamma}$ a tumor promoter; and what is the future of $PPAR{\gamma}$ in colon cancer prevention?

The Relationship among Menopausal Symptoms, Competency of Self-Care Agency and Social Support in Middle-aged Woman (중년 여성의 폐경 증상경험과 자가관리 역량, 사회적 지지와의 관계)

  • Choi, Seong Mi;Ko, Il Sun;Choi, Mo Na;Jang, Yeon Soo
    • Journal of Korean Clinical Nursing Research
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    • v.21 no.1
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    • pp.105-115
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    • 2015
  • Purpose: This descriptive correlational study was intended to analyze the relationship among menopausal symptoms. competency of self-care agency and social support in middle-aged women. Methods: Participants in the study were 140 women who were 45-60 years of old. Data were collected using structured questionnaires and analyzed using descriptive statistics., t-test, ANOVA, $Scheff{\grave{e}}^{\prime}s$ test and Pearson correlation coefficients. Results: The frequency and discomfort of menopausal symptom were low, but the mean discomfort score were higher than frequency score. Middle-aged women with lower competency of self care experienced more frequent menopausal symptoms (t=-0.28, p=.001) and more discomfort (t=-0.24, p=.004). However, There was no significant difference in menopausal symptoms according to social support. Conclusion: Nursing interventions to enhance competency of self-care agency in middle-aged women are required in order to reduce the discomfort of menopausal symptoms.