• 대한한방내과학회지
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• 제26권4호
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• pp.785-794
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• 2005

Little is known concerning the pathophysiology and symptomatology of gastric dysmotility of patients who have sought treatment in eastern traditional medicine. The aim of this study was to investigate gastric electrical activity and clinical characteristics between gastroparesis and non-gastroparetic functional dyspepsia(FD) and assess the necessity to distinguish them for eastern traditional medical treatment. 60 patients were surveyed by questionnaire. Gastric electrical activity was recorded and analyzed using electrogas-trography. Patients were divided into gastroparesis and non-gastroparetic FD by 1.0 of power ratio. Healthy persons were used as reference. Postprandial normogastria of gastroparesis decreased and that of non-gastroparetic functional dyspepsia increased compared before and after meals. Suggested causes of onset were the meat diets that most patients were on in the gastroparesis group, and that drugs that patients in the non-gastroparetic FD group were taking. Distribution of main symptom was equally regular in patients with gastroparesis, but patients with non-gastroparetic FD showed mainly upper abdominal pain and fullness. Values for the gastroparesis group were double those for the non-gastroparesis FD group in frequency of upper GI endosopic examination. Results suggest that effective application of eastern traditional medical treatment requires that first a clear distinction be made in state of gastric dysmotility and clinical characteristics of gastroparesis and non-gastroparesis FD when treating dyspepsia.

• 대한한방내과학회지
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• 제26권2호
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• pp.390-397
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• 2005

Background & Object: The aim of this study was to investigate the association of degree of fatigue and gastric motility, measured by EGG, with skin sympathetic tone or cardiovascular reactivity in patients with functional dyspepsia. Methods: Subjects were 56 patients with Functional dyspepsia and eight healthy people. Degree of fatigue was assessed by questionnaires consisting of subjective complaints of fatigue. Skin sympathetic tone was measured by Ryodoraku Score and Cardiovascular Reactivity was checked by Pulse diagnostic apparatus. Gastric motility was estimated by EGG. First, all patients were divided into two groups by Ryodoraku Score $40{\mu}A$(below and above). Second, they were subdivided into two groups by Cardiovascular Reactivity(decreased and increased or not decreased). Estimates were made on the extent differences of degree of fatigue or state of gastric motility in each group. Results: 1. Fatigue scores was significantly higher in females and in the Ryodoraku-Score-below-$40{\mu}A$ group. It was higher in the decreased cardiovascular reactivity group than the increased group, but to no significanct extent. Also, gastric motility was better in the Ryodoraku-Score-above-$40{\mu}A$, group than in the below group. Conclusions: These results suggest that degree of fatigue and gastric motility are associated with skin sympathetic tone, but not associated with cardiovascular reactivity, and that $40{\mu}A$ is a useful cutoff point in Ryodoraku Score for assessing degree of fatigue in functional dyspepsia patients.

• 대한한방내과학회지
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• 제27권2호
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• pp.510-520
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• 2006

Objectives: The aim of this study was to investigate the correlation between fatigue degree and Comprehensive diagnosis of Qui Xui Shui in patients with functional dyspepsia. There again, we investigated an association between scores obtained from Comprehensive diagnosis of Qui Xui Shui and state of skin sympathetic tone or cardiovascular reactivity. Methods: Subjects were 56 patients with Functional dyspepsia and 8 healthy People. Fatigue degree was assessed by questionnaires consisting of subjective complaints of fatigue. Comprehensive diagnoais of Qui Xue Shui was investigated by questionnaire and physical examination, total score and composition score were calculated from the symptom score. Skin sympathetic tone was measured by Ryodoraku Score(RS) and Cardiovascular Reactivity(CV Reactivity) was checked by Pulse diagnostic apparatus. All patients were divided into two groups by RS $40{\mu}A$(below and above) or by CV Reactivity(decreased and increased or not decreased). Results: There was highly significant correlation between Fatigue Degree and total score and each composition score of Comprehensive diagnosis of Qui Xui Shui. And total score of patients was significantly higher than that of health controls : in the patients, females than males. Significance related with the level of RS $40{\mu}Aor$ the state of CV Reactivity were not remarkable in both patients and health control group. Conclusions: Fatigue degree seems to have a special feature reflecting the state of Comprehensive Diagnosis of Qui Xui Shui in patients with functional dyspepsia.

• 대한한방내과학회지
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• 제25권4호
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• pp.346-355
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• 2004

Background & Object : The aim of this study was to investigate the usefulness of electrogastrography on differential diagnosis of deficiency or excess Condition in patients with functional dyspepsia Methods : Selected symptoms for diagnosis of deficiency and excess in functional dyspepsia have been reviewed in some literatures, notably within Oriental medicine, Donguibogam and Gogeumdoseojipseong-uibujeolrok. This is what was investigated in this study. 93 patients (male 32, female 61) were divided into three groups; Non-pain group, Pre-treatment pain group (chief complain was abdominal pain at the first medical examination), and Mid-treatment pain group(they had no pain at the time of first medical examination, but showed abdominal pain within two weeks). 10 healthy people participated as normal controls. Gastric motility were recorded and analyzed using electrogastrography during fasting and postprandial period. In assessment, effectiveness was divided into validity, sensitivity and specificity. Results : Epigastric pain reflected the tendency for excess condition in comprehensive diagnosis, which was linked with postprandial arrhythmia in electrogastrography(p=0.001). Postprandial arrhythmia detected abdominal pain with a validity of 78.6%, a sensitivity of 79.2%, and a specificity of 78%(p<0.001). Conclusions : Results 1Tom Postprandial arrhythmia in electrogastrography support that the index of excess condition in the comprehensive diagnosis of symptoms is useful for patients with functional dyspepsia.

• Journal of Acupuncture Research
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• 제27권1호
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• pp.129-135
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• 2010

Objectives : The purpose of this research was to examine that effect of Sosang($LU_1$)-Eunbaek($SP_1$) bloodletting was similar to effect of Sa-kwan $LI_4$) and Taechung($LR_3$)> acupuncture on pain and discomfort of acute dyspepsia in upper abdomen. Methods : We divided 36 patients with acute dyspepsia into two groups and treated Group A with Sosang($LU_{11}$)-Eunbaek($SP_1$) bloodletting and Group B with Sa-kwan $LI_4$) and Taechung($LR_3$)> acupuncture. Pain and discomfort in upper abdomen was measured by Visual Analogue Scale(VAS) scores of the two groups before treatment and after 15 minutes to treat. Results : Both group A and B represented effective improvement in VAS of pain and discomfort in upper abdomen. And there was no difference between A group and B group statistically. Conclusions : It is suggested that Sosang($LU_{11}$)-Eunbaek($SP_1$) bloodletting may have similar effect compared with Sa-kwan $LI_4$) and Taechung($LR_3$)> acupuncture on acute dyspepsia treatment.

• 사상체질의학회지
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• 제33권3호
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• pp.1-15
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• 2021

Introduction The clinical usefulness of Sasang Digestive Function Inventory (SDFI) for analyzing Sasang type-specific pathophysiological symptom was illustrated repeatedly. It was revised to enhance its validity, reliability and clinical usefulness, however its clinical studies supporting these were not sufficient yet. Methods 193 healthy university students responded once to Nepean Dyspepsia Index-Korean (NDIK), Functional Dyspepsia-Related Quality of Life (FDQOL), and Dutch Eating Behavior Questionnaire (DEBQ), and twice to SDFI with four weeks of interval. The Body Mass Index (BMI) and Ponderal Index (PI) were also calculated. The 4-week test-retest reliability and correlation coefficients between NDIK, FDQOL, DEBQ, and SDFI were examined using Pearson's correlation. The significant differences between Sasang types in SDFI and its subscales were examined using ANCOVA with the age as covariate. Results The range of test-retest reliability for SDFI and its subscales was from 0.801 to 0.887. The SDFI-total correlated positively with BMI (r=0.323) and DEBQ-External Eating (r=0.433), while the SDFI-Digestion negatively with NDIK (r=-0.472) and FDQOL-total (r=-0.364). The SDFI-Habit correlated positively with BMI (r=0.310) and DEBQ-total (r=0.481), and the SDFI-Appetite with DEBQ-total (r=0.322). The SDFI-total, SDFI-Digestion, and SDFI-Habit scores of Tae-Eum type (35.6±6.25, 12.38±3.24 and 9.89±3.38, respectively) were significantly bigger than those of So-Eum type (29.84±8.31, 9.93±4.28 and 7.66±3.96). Discussion The SDFI was found to be an objective clinical measure with sufficient concurrent validity for measuring eating behavior and quality of life related to overeating and dyspepsia, and illustrated distinctive differences between Sasang types. It might be useful for the effective medical education and integrative medical practice.

• 대한예방한의학회지
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• 제27권1호
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• pp.43-52
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• 2023

Objectives : The aim of this study was to evaluate the differences in the abdominal cavity between functional dyspepsia patients and healthy people using an algometer combined with an ultrasound device. Methods : A non-randomized, controlled, pilot trial was conducted. Thirty patients in the experimental group and fifteen participants in the control group were recruited. We collected demographical data, and measured abdominal circumference, height of the body cavity, subcutaneous fat thickness, visual analogue scale of dyspepsia symptoms in the experimental group, depth of algometer and pressure of algometer when pressure pain occurred, and the whole ultrasonic image from the beginning of pressurization to the time when pressure pain occurred. The measurements were carried out twice with the duration of 1 week. Generalized linear regression was conducted to adjust baseline characteristics. Results : A total of 45 participants (30 in experimental group, 15 in control group) were recruited and finished the trial. Females were recruited more in the experimental group than in the control group and it was statistically significant. The difference in thickness of abdominal cavity between a second before the pressure pain and at the time when pressure pain occurred was statistically significant on 1st visit, and other measurements were not statistically significant. From the results of the regression analysis, the difference between two groups was statistically significant in the differences in the thickness of stomach and up to abdominal aorta on 1st visit, and the thickness of stomach on 2nd visit, and other measurements were not statistically different. Conclusions : According to the results, there were not statistically significant differences in abdominal examination when pressure pain occurred between dyspepsia patients and healthy people. Further studies are warranted to assess the abdominal examination using devices including algometer and ultrasound devices, regarding the results of the present study.

• 보험의학회지
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• 제17권
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• pp.31-34
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• 1998

• 동의신경정신과학회지
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• 제3권1호
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• pp.107-116
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• 1992

In order to study the effect and safety of HPS-A on various digestive symptom, it was taken 3 times a day for 2 weeks on 31 patients. The results were as follows ; 1. The sex distribution was male 42% and female 58% 2. The age distribution was thirties 35% twenties 20%, forties 19% 3. The average improvement rate after 1 week was 85.2% and improvement rate of each symptom was epigastric soreness 89.9%, dyspepsia 85.1%, hunger pain 84.6% 4. The average improvement rate after 2 weeks was 94.5% and improvement rate of each symptom was epigastric soreness 96.6%,hunger pain 96.5%, dyspepsia 96.3% 5. No cases were showen side effects. Aecording to the above results, it is proved that PHS-A can be applied to care gastritis and early peptic ulcer.

• 동의생리병리학회지
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• 제24권1호
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• pp.22-25
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• 2010

Hyangsapyeongwi-san has been used for various gastrointestinal diseases in Oriental medicine. Nevertheless, there is little known to scientific evidence for its efficacy and mechanism. This study was aimed to investigate effects of Hyangsapyeongwi-san in gastrointestinal diseases through the analysis of articles. A total of 15 articles were selected from PubMed, KTKP, and Weipu. The selected articles were analyzed according to three aspects of study types, target diseases and its efficacy, and results of clinical studies. Hyangsapyeongwi-san has positive effects in gastrointestinal disorders, such as prevent gastric mucosal injury, improve hyperacidity and dyspepsia, protect oxidative damage, and antitumor effects and enhance both cellular and humoral immunity. However, it proved insufficient to confirm its efficacy owing to lack of clinical studies of high quality. So, we need well designed studies to verify clinical efficacy of Hyangsapyeongwi-san hereafter.