• 제목/요약/키워드: dynamic culture

검색결과 356건 처리시간 0.03초

튜머로이드-혈관신생 상호작용의 가시화를 위한 개방형 구조 미세유체 칩 개발 (Development of open-top microfluidic chip for visualization of interactions between tumoroids and angiogenic sprouting)

  • 김승규;김지원;박준하;오상윤;신현정;전성윤
    • 한국가시화정보학회지
    • /
    • 제18권3호
    • /
    • pp.84-89
    • /
    • 2020
  • Cancer cells secrete angiogenic factors, and nearby vasculatures make new blood vessels essential for cancer development and metastasis in response to these soluble factors. Many efforts have been made to elucidate cancer-endothelial cell interactions in vitro. However, not much is known due to the lack of a suitable co-culture platform. Here, we introduce a 3D printing-based microfluidic system that mimics the in vivo-like cancer-endothelial cell interactions. The tumoroids and endothelial cells are co-cultured, physically separated by porous fibrin gel, allowing communication between two cell types through soluble factors. Using this microfluidic system, we were able to visualize new vessel formation induced by tumoroids of different origins, including liver, breast, and ovary. We confirmed that the ovarian tumoroids most induced angiogenesis while the other two cancer types suppressed it. Utilization of the proposed co-culture platform will help the researchers unveil the underlying mechanisms of the dynamic interplay between tumor and angiogenesis.

레일연마에 따른 레일 파상마모 저감 효과 분석을 위한 실험적 연구 (Experimental Study to analyze Effect of Rail Corrugation Reduction according to Rail Grinding)

  • 최정열;정천만;정지승
    • 문화기술의 융합
    • /
    • 제7권4호
    • /
    • pp.801-806
    • /
    • 2021
  • 레일 파상마모는 레일표면 요철 관리기준의 부재로 인해 지속적으로 증가하는 추세에 있다. 레일파상마모는 승차감 저하와 궤도 유지관리 물량증대 등과 같은 다양한 문제점을 야기 시키고 있다. 본 논문에서는 레일 파상마모 발생구간을 대상으로 레일 연마 전, 후에 대한 레일요철 측정 및 궤도계측(동적 윤중, 변위, 가속도)을 수행하여 레일 파상마모가 궤도부담력에 미치는 영향을 분석하였다. 또한 레일 파상마모 저감을 위해 실시한 레일연마는 레일 파상마모로 인해 발생되는 추가적인 궤도부담력 저감에 매우 효과적이었음을 실험적으로 입증하였다.

Study on wind-induced vibration response of Jiayuguan wooden building

  • Teng Y. Xue;Hong B. Liu;Ting Zhou;Xin C. Chen;Xiang Zhang;Zhi P. Zou
    • Wind and Structures
    • /
    • 제37권3호
    • /
    • pp.245-254
    • /
    • 2023
  • In this paper, the wind-induced response of Jiayuguan wooden building (world cultural heritage) in Northwest China was studied. ANSYS finite element software was used to establish four kinds of building models under different working conditions and carry out modal analysis. The simulation results were compared with the field dynamic test results, obtaining the model which reflects the real vibration characteristics of the wooden tower. Time history data of fluctuating wind speed was obtained by MATLAB programming. Time domain method and ANSYS were used to analyze the wind-induced vibration response time history of Jiayuguan wooden building, obtaining the displacement time history curve of the structure. It was suggested that the wind-induced vibration coefficient of Jiayuguan wooden building is 1.76. Through analysis of the performance of the building under equivalent static wind load, the maximum displacement occurs in the three-story wall, gold column and the whole roof area, and the maximum displacement of the building is 5.39 cm. The ratio of the maximum stress value to the allowable value of wood tensile strength is 45 %. The research results can provide reference for the wind resistant design and protection of ancient buildings with similar structure to Jiayuguan wooden tower.

Modeling The Dynamics of Grit; Goal, Status, Effort & Stress (GSES)

  • Sangdon Lee;Jungho Park
    • International Journal of Advanced Culture Technology
    • /
    • 제11권2호
    • /
    • pp.10-29
    • /
    • 2023
  • Grit or perseverance as a factor for student success and life has gained increasing attention. Statistical methods have been the norm in analyzing various aspects of grit, but they do not address the transient and dynamic behavior well. We, for the first time, developed two linear dynamical models that specifically address the feedback structure of a child's desire to achieve a high grade point average (GPA) and the necessary effort that will increase stress between parents and a child. We call the dynamical model as GSES (Goal, Status, Effort & Stress). The two dynamical models incorporate the positive (i.e., achieving a high GPA) and the negative sides (i.e., effort and elevated stress and thus unhappiness) for being gritty or perseverant. Different types of parenting style and a child's characteristics were simulated whether parents and a child are empathetic or stubborn to their expectations and stress (i.e., willing or unwilling to change). Simulations show that when both parents and a child are empathetic to each other's expectation and stress, the most stable situations with minimal stress and effort occur. When a stubborn parent's and a stubborn child were studied together, this resulted in the highest elevation of stress and effort. Stubborn parents and a complying or empathetic child resulted in considerably high stress to a child. Interference from parents may unexpectedly result in a situation in which a child's stress is seriously elevated. The GSES model shows the U-shaped happiness curve (i.e., reciprocal of stress) caused by the increasing and then decreasing goal

도심 재구성에서의 사회 커뮤니티조성에 관한 검토 (A Study on the Creation of Social Communities in Urban Reconstruction)

  • 루즈옌
    • 문화기술의 융합
    • /
    • 제9권5호
    • /
    • pp.815-819
    • /
    • 2023
  • 현재 중국의 도시 공간은 점진적인 개발에서 재고 변형으로 점차 변화하고 있다. 도시 공동체의 계획 개발 목표도 물질적 공간 건설에서 인문 사회의 지속 가능한 발전 방향으로 전환되었다. 현재 주거생활에 중점을 둔 단일 위도의 지역사회 계획 및 건설은 지역사회 생활 생산의 다차원적 요소를 간과하여 지역사회 간의 냉담한 관계, 인간과 환경 간의 관계 형성 어려움 등 많은 문제를 초래한다. 따라서 이 글은 지역사회의 시공간적 연속적 통일에서 지역사회의 사회성을 재인식하고, 지역사회의 중앙과 민간의 여양 명확히 하며, 일상생활의 시작점으로 하여 지역사회의 역동적인 조성 방법과 방법을 재탐색한다.

A comparative study of the Metaverse platforms through college students'experiences using the Metaverse

  • Sanghui Park;Kiyoon Kim
    • International Journal of Advanced Culture Technology
    • /
    • 제12권2호
    • /
    • pp.110-118
    • /
    • 2024
  • This study was conducted to analyze the metaverse usage behavior of college students through in-depth interviews and to explore the characteristics of the major metaverse platforms with a focus on keywords. This study derived elements such as metaverse participation activities, real-world order, metaverse system, presence, and self-expression from previous research. This study examined how college students who use the metaverse perceive these variables. We present the following research results: First, the college students who participated in the study showed interest in content with many interactive elements on the metaverse platform and appeared to participate more actively in such content. Second, college students cited the ability to engage in economic activities in the metaverse as their greatest strength. It was expected that social norms applied in the real world would also be applied in the metaverse. Third, the Metaverse system, such as the Metaverse UI, UX, and servers, was found to be a factor that needs to meet users' expectations and hinders immersion. In this study, the characteristics of the metaverse platform were analyzed, focusing on essential keywords from in-depth interviews. The analysis results are as follows: It was expressed with keywords such as Zepeto has 'avatar' and 'personality expression,' Ifland has 'free decoration' and 'communication convenience,' Gathertown has 'movement convenience' and 'video chat.' Roblox has 'game-based' and 'dynamic.'

A Probe into The Modernity of Chinese Oil Painting

  • Huang Yihan
    • International Journal of Advanced Culture Technology
    • /
    • 제12권3호
    • /
    • pp.199-205
    • /
    • 2024
  • Background: The integration of new media technologies marks a significant evolution in public art. Shifting from traditional forms to a digital and virtual environment diversifies artistic expression and transforms how art interacts with the public, fostering a more inclusive and engaging public sphere. Methods: Using a qualitative research design, this study explores the impacts and roles of new media public art within virtual spaces. Through a series of in-depth case studies, it examines how virtualization technologies enhance interactivity, immersion, and public accessibility of art, thus revolutionizing its engagement and reception. Results: Findings reveal that spatial virtualization significantly enriches the interactive potential and diversity of public art. It facilitates novel forms of artistic expression and immersive experiences, promoting deeper levels of audience engagement and participation. Challenges such as technological accessibility and the necessity for interdisciplinary collaboration are also identified. Conclusions: We advocate for a strategic and deliberate integration of virtual technologies in public art projects, emphasizing the need for a comprehensive approach that considers the perspectives of artists, patrons, and the public. We believe that addressing the digital era's challenges and opportunities can enable new media public art to leverage virtualization effectively, fostering a dynamic and participatory art landscape.

Research on Hot-Threshold based dynamic resource management in the cloud

  • Gun-Woo Kim;Seok-Jae Moon;Byung-Joon Park
    • International Journal of Advanced Culture Technology
    • /
    • 제12권3호
    • /
    • pp.471-479
    • /
    • 2024
  • Recent advancements in cloud computing have significantly increased its importance across various sectors. As sensors, devices, and customer demands have become more diverse, workloads have become increasingly variable and difficult to predict. Cloud providers, connected to multiple physical servers to support a range of applications, often over-provision resources to handle peak workloads. This approach results in inconsistent services, imbalanced energy usage, waste, and potential violations of service level agreements. In this paper, we propose a novel engine equipped with a scheduler based on the Hot-Threshold concept, aimed at optimizing resource usage and improving energy efficiency in cloud environments. We developed this engine to employ both proactive and reactive methods. The proactive method leverages workload estimate-based provisioning, while the reactive Hot-Cold Scheduler consists of a Predictor, Solver, and Processor, which together suggest an intelligent migration flow. We demonstrate that our approach effectively addresses existing challenges in terms of cost and energy consumption. By intelligently managing resources based on past user statistics, we provide significant improvements in both energy efficiency and service consistency.

상담자의 어른역할이 상담성과에 미치는 영향 - '이야기 방식'에 기초한 보고 형태 - (The Influence of an Elder's Role of Counselor on Counseling Result - Reporting Style Based on 'Story Making Methods' -)

  • 장성숙
    • 한국심리학회지 : 문화 및 사회문제
    • /
    • 제16권3호
    • /
    • pp.311-329
    • /
    • 2010
  • 문화권에 따라 상담자의 역할은 달라질 필요가 있다. 서구의 수평적인 개인주의 사회에서는 내담자의 자율성을 강조하는 편이지만, 동양권에 속하는 수직적 권위사회인 우리나라에서는 내담자의 사회성을 중요하게 여기기 때문이다. 뿐만 아니라 한국사회에서는 상담자가 치료자 역할 이외에 교육자 내지는 양육자로서 기능하기를 기대하는 편이다. 한국적 상담 모형으로 제기된 현실역동 상담에서는 '상담의 현재화'와 '상담자의 어른역할'을 양대 기본 골격으로 꼽고 있는데, 본 연구에서는 '상담자의 어른역할'이 실제 상담 사례에서 어떠한 상담성과를 이루는가 하는 것을 '이야기 방식'의 형태로 보여주고 있다. '이야기 방식'은 질적 연구의 한 방안으로서 내용을 축약할 수 있는 간결성과 진행에 대한 해설로 인해 상담 사례를 연구할 때 원자료를 제시하는 축어록 방식보다는 유용하다고 본다. 상담자가 어른으로서 역할을 하는 과정에는 한국적 상담모형으로 제안된 현실역동 상담의 특성들인 문제의 실체파악, 심정 헤아리기, 외부현실 강조, 역할 중시. 직면 활용하기, 부모-자녀관계 강조, 사회성 촉진 등이 반영되어 나타나고 있다.

  • PDF

원심모형실험을 이용한 그룹 삼축 마이크로파일의 동적거동 평가 (Evaluation of the Dynamic Behavior of Inclined Tripod Micropiles Using Dynamic Centrifuge Test)

  • 김윤아;권태혁;김종관;한진태;김재현;안성율
    • 한국지반공학회논문집
    • /
    • 제39권12호
    • /
    • pp.93-102
    • /
    • 2023
  • 최근 건축물 구조 기준의 개정으로 말뚝 기초의 내진성능 강화가 강조되고 있음에도 불구하고, 현재 건축물 기초의 내진설계는 비용과 시공상의 어려움으로 충분한 시행이 이루어지지 않고 있다. 본 연구에서는 지진 시 수평 및 수직 하중에 효과적으로 대응할 수 있는 구조로 제안된 삼축 마이크로파일(TMP)의 지진 시 동적 거동을 평가하고자 하였다. 동적 원심모형실험을 통해 설치 각도가 15°인 그룹 삼축 마이크로파일과 설치 각도가 0°인 연직 군말뚝의 가속도, 변위, 휨모멘트, 축력 등의 동적 거동이 비교 분석되었다. 실험 결과에 따르면 가속도와 수평 및 수직 변위 결과를 바탕으로 살펴보았을 때 탁월 주기가 0.5 초 미만인 실지진파 가진 조건에서 경사진 그룹 삼축 마이크로파일의 내진성능은 연직 군말뚝보다 좋거나 비슷한 수준으로 평가된다. 그러나 Sine 2Hz와 같은 장주기의 강한 지진 가진 시에는 경사진 삼축 마이크로파일의 응답이 전반적으로 수직 마이크로파일보다 크게 나타났다. 협소한 공간에서 기존 시설물의 단주기 지진파에 대한 응답을 줄이는 내진보강이 필요한 경우 경사진 삼축 마이크로파일이 수직 마이크로파일의 대안으로 활용 될 수 있을 것으로 판단된다.