• Title/Summary/Keyword: dynamic CT

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Simulation of lesion-to-liver contrast difference curves in Dynamic Hepatic CT with Pharmacokinetic Compartment Modeling (Pharmacokinetic Compartment Modeling을 이용한 나선식 CT 에서의 간암-간 대조 곡선의 Simulation)

  • Kim, S.J.;Lee, K.H.;Kim, J.H.;Min, B.G.
    • Proceedings of the KOSOMBE Conference
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    • v.1998 no.11
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    • pp.271-272
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    • 1998
  • Contrast-enhanced CT has an important role in the assessment of liver lesions. However, the optimal protocol to get most effective result is not clear. The main principle for deciding injection protocol is to optimize lesion detectability by rapid scanning when lesion-to-liver contrast is maximum. For this purpose, we developed a physiological model of contrast medium enhancement based on the compartment modeling and pharmacokinetics. Blood supply to liver was modeled in two paths. This dual supply character distinguishes the CT enhancement of liver from that of the other organs. The first path is by hepatic artery and the second is by portal vein. It is assumed that only hepatic artery can supply blood to hepatocellular carcinoma (HCC) compartment. It is known that this causes the difference of contrast enhancement between normal liver tissue and hepatic tumor. By solving differential equations for each compartment simultaneously using computer program Matlab, CT contrast-enhancement curves were simulated. Simulated enhancement curves for aortic, hepatic, portal vein, and HCC compartments were compared with mean enhancement curves from 24 patients exposed to the same protocols as simulation. These enhancement curves were in a good agreement. Furthermore, we simulated lesion-to-liver curves for various injection protocols, and analyzed the effects. These may help to optimize the scanning protocols for good diagnosis.

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A Study on Establishment of Essential Performance Evaluation Criteria for C-arm Computed Tomography (C-arm CT의 필수 성능평가 기준 마련을 위한 연구)

  • Kim, Eun-Hye;Park, Hye-Min;Kim, Jung-Min
    • Journal of radiological science and technology
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    • v.45 no.2
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    • pp.127-134
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    • 2022
  • In order to overcome the image quality limitations of the conventional C-arm, a flat panel detector (FPD) is used to enhance spatial resolution, detective quantum efficiency, frame rate, and dynamic range. Three-dimensional (3D) visualized information can be obtained from C-arm computed tomography (CT) equipped with an FPD, which can reduce patient discomfort and provide various medical information to health care providers by conducting procedures in the interventional procedure room without moving the patient to the CT scan room. Unlike a conventional C-arm device, a C-arm CT requires different basic safety and essential performance evaluation criteria; therefore, in this study, basic safety and essential performance evaluation criteria to protect patients, medical staff, and radiologists were derived based on International Electrotechnical Commission (IEC) standards, the Ministry of Food and Drug Safety (MFDS) standards in Korea, and the rules on the installation and operation of special medical equipment in Korea. As a result of the study, six basic safety evaluation criteria related to electrical and mechanical radiation safety (leakage current, collision protection, emergency stopping device, overheating, recovery management, and ingress of water or particulate matter into medical electrical (ME) equipment and ME systems: footswitches) and 14 essential performance evaluation criteria (accuracy of tube voltage, accuracy of tube current, accuracy of loading time, accuracy of current time product, reproducibility of radiation output, linearity and consistency in radiography, half layer value in X-ray equipment, focal size and collimator, relationship between X-ray field and image reception area, consistency of light irradiation versus X-ray irradiation, performance of the mechanical device, focal spot to skin distance accuracy, image quality evaluation, and technical characteristic of cone-beam computed tomography) were selected for a total of 20 criteria.

The Parallel Operation of ZVT-Full Bridge Converter with Dynamic Current Shared Inductor (동적 전류분담 인덕터를 적용한 ZVT 풀 브리지 컨버터의 병렬 운전)

  • Bae, Jin-Yong;Kim, Yong;Baek, Soo-Hyun;Kwon, Soon-Do;Lee, Kyu-Hoon;Kim, Cherl-Jin
    • Proceedings of the KIEE Conference
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    • 2001.07b
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    • pp.942-945
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    • 2001
  • This paper presents parallel operation of ZVT(Zero Voltage Transition) Full Bridge Converter with Dynamic Current Shared Inductor. In the conventional method, CT(Current Transformer) have been used to share the load current equally with converters. In this system, at parallel operation of ZVT Full Bridge Converter, dynamic current shared inductor divides the same current of unit converter and ZVT circuit aids to high efficiency. This method which is proposed to compare in the conventional method will do simple control circuit. To show the superiority of this converter is verified through the experiment with a 2kW, 50kHz prototype converter.

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Myocardial Coverage and Radiation Dose in Dynamic Myocardial Perfusion Imaging Using Third-Generation Dual-Source CT

  • Masafumi Takafuji;Kakuya Kitagawa;Masaki Ishida;Yoshitaka Goto;Satoshi Nakamura;Naoki Nagasawa;Hajime Sakuma
    • Korean Journal of Radiology
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    • v.21 no.1
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    • pp.58-67
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    • 2020
  • Objective: Third-generation dual-source computed tomography (3rd-DSCT) allows dynamic myocardial CT perfusion imaging (dynamic CTP) with a 10.5-cm z-axis coverage. Although the increased radiation exposure associated with the 50% wider scan range compared to second-generation DSCT (2nd-DSCT) may be suppressed by using a tube voltage of 70 kV, it remains unclear whether image quality and the ability to quantify myocardial blood flow (MBF) can be maintained under these conditions. This study aimed to compare the image quality, estimated MBF, and radiation dose of dynamic CTP between 2ndDSCT and 3rd-DSCT and to evaluate whether a 10.5-cm coverage is suitable for dynamic CTP. Materials and Methods: We retrospectively analyzed 107 patients who underwent dynamic CTP using 2nd-DSCT at 80 kV (n = 54) or 3rd-DSCT at 70 kV (n = 53). Image quality, estimated MBF, radiation dose, and coverage of left ventricular (LV) myocardium were compared. Results: No significant differences were observed between 3rd-DSCT and 2nd-DSCT in contrast-to-noise ratio (37.4 ± 11.4 vs. 35.5 ± 11.2, p = 0.396). Effective radiation dose was lower with 3rd-DSCT (3.97 ± 0.92 mSv with a conversion factor of 0.017 mSv/mGy∙cm) compared to 2nd-DSCT (5.49 ± 1.36 mSv, p < 0.001). Incomplete coverage was more frequent with 2nd-DSCT than with 3rd-DSCT (1.9% [1/53] vs. 56% [30/54], p < 0.001). In propensity score-matched cohorts, MBF was comparable between 3rd-DSCT and 2nd-DSCT in non-ischemic (146.2 ± 26.5 vs. 157.5 ± 34.9 mL/min/100 g, p = 0.137) as well as ischemic myocardium (92.7 ± 21.1 vs. 90.9 ± 29.7 mL/min/100 g, p = 0.876). Conclusion: The radiation increase inherent to the widened z-axis coverage in 3rd-DSCT can be balanced by using a tube voltage of 70 kV without compromising image quality or MBF quantification. In dynamic CTP, a z-axis coverage of 10.5 cm is sufficient to achieve complete coverage of the LV myocardium in most patients.

Activities to attain integrity of generator current transformer (발전기 변류기 건전성 확보를 위한 연구)

  • Cho, C.W.;Cho, S.T.;Yang, K.H.;Ann, K.J.;Lee, H.Y.
    • Journal of Power System Engineering
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    • v.16 no.1
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    • pp.19-23
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    • 2012
  • This thesis is the result of conducting an analysis to find the solution to the phenomenon of power stoppage due to the disconnection of a CT (Current Transformer) because of vibration. The CT which measures the most essential current is used in power industries as part of a generator protection relay. When it comes to the bottom plate of a CT, nonconductor; such as bakelite and laminates; these material elements should be used because it is impossible to utilize the conductor when measuring the current of a generator which carries a high current if you use other materials. These nonconductor's material properties are irregular and interpretation errors often occur because the weight is light. In addition, since the change of dynamic characteristics which are related to the temperature often occur, it is important to match the real situation by considering an error of interpretation rather than selecting the quality of the material. Lastly, the conclusion that the study drew is that it is possible to avoid the resonance by utilizing three changes to the components to solve the problem concerning the high vibration which is caused by non-conductive objects. These changes are the most crucial points in this thesis: First, material changes to the Plate. Second, weight changes to the Coil. Third, thickness changes to the Plate.

Computer Tomography and Magnetic Resonance Image Manifestations of Primary Hepatic Neuroendocrine Cell Carcinomas

  • Huang, Juan;Yu, Jian-Qun;Sun, Jia-Yu
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.6
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    • pp.2759-2764
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    • 2014
  • Aim: This study aims to investigate the manifestation of CT, MRI and dynamic enhanced scans for primary hepatic neuroendocrine cell carcinoma. Methods: CT or MRI arterial and venous phase scan images of 19 cases of pathologically confirmed PHNEC were retrospectively analyzed. Results: 14 cases (73.68%) with single lesion, 5 cases (26.3%) with multiple lesions, with an average diameter of 13.2 cm. Some 12 cases (63.16%) showed inhomogeneous enhancement, seven cases (36.8%) showed homogeneous enhancement, 13 cases (68.4%) demonstrated significant enhancement in the arterial phase, 13 cases (68.4%) had significantly enhanced portal venous phase including 7 cases (36.8 %) with portal venous phase density or signal above the arterial phase and 5 cases (26.3%) with the portal vein density or signal below the arterial phase. Seven cases (36.8%) had continued strengthened separate shadows in the center of the lesion. Thrombosis were not seen in portal veins. Conclusion: CT and MRI images of liver cell neuroendocrine carcinoma have certain characteristics that can provide valuable information for diagnosis and differential diagnosis.

Dynamic Computed Tomographic Characteristics of aColorectal Leiomyoma in a Dog (개에서 발생한 결장 평활근종에 대한 동적 컴퓨터 단층촬영 소견 1례)

  • Park, Noh-Won;Chung, Wook-Hun;Han, Jae-Woong;Eom, Ki-Dong
    • Journal of Veterinary Clinics
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    • v.32 no.2
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    • pp.200-204
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    • 2015
  • A 12-year-old neutered male Shih Tzu presented with constipation and dyschezia. Abdominal radiographs showed distension of the descending colon and dorsal compression of the colon by a soft tissue mass. The mass was well-marginated with homogeneous soft tissue attenuation and showed no evidence of metastasis on computed tomography (CT). The dynamic CT showed a consistently mild contrast enhancement. The perfusion and capillary permeability were lower than those of the gluteal muscle. The tentative imaging diagnosis was a benign intrapelvic tumor, which rarely shows angiogenesis. The mass was excised, and a leiomyoma was confirmed by histopathologic examination.

Quantitative Assessment of Salivary Gland washout in Clinically Healthy Dogs

  • Jang, Won-seok;Hwang, Tae-sung;Jung, Dong-in;Lee, Jae-hoon;Lee, Hee-chun
    • Journal of Veterinary Clinics
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    • v.37 no.1
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    • pp.28-33
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    • 2020
  • The aims of this study were to obtain the normal ranges of enhancement parameters for salivary gland in dynamic CT and to investigate the effects of fasting time on contrast enhancement in clinically normal beagle dogs. With five healthy beagle dogs, dynamic CT examination was performed according to fasting times (as fasting times, 12hours, 0 min, 20 min, 40 min, 1 hours, 6 hours, 24 hours). In normal beagles with 12hours fasting, enhancement parameters through the preliminary study were as follows: ImaxA - 472 .49 ± 19.01 HU; ImaxS - 138.95 ± 6.2 5 HU; TmaxA - 25.8 ± 1.79 sec; TmaxS - 69.0 ± 23.11 sec; Teq - 80.5 ± 6.61 sec; T-Aeq - 54.5 ± 5.51 sec (Imax - peak enhancement; Tmax - time to peak enhancement; Teq - time to equilibrium phase; T-Aeq - time between peak enhancement in the common carotid artery and onset of the equilibrium phase; A - common carotid; S - submandibular gland; HU - Hounsfield unit). Additionally, ImaxA and ImaxS were significantly increased in 40 min after eating. Because these results associated with postprandial hemodynamic changes can make the diagnosis of salivary gland diseases more difficult, sufficient fasting time is important for accurate diagnosis.

Influence of Heart Rate and Innovative Motion-Correction Algorithm on Coronary Artery Image Quality and Measurement Accuracy Using 256-Detector Row Computed Tomography Scanner: Phantom Study

  • Jeong Bin Park;Yeon Joo Jeong;Geewon Lee;Nam Kyung Lee;Jin You Kim;Ji Won Lee
    • Korean Journal of Radiology
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    • v.20 no.1
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    • pp.94-101
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    • 2019
  • Objective: To investigate the efficacy of motion-correction algorithm (MCA) in improving coronary artery image quality and measurement accuracy using an anthropomorphic dynamic heart phantom and 256-detector row computed tomography (CT) scanner. Materials and Methods: An anthropomorphic dynamic heart phantom was scanned under a static condition and under heart rate (HR) simulation of 50-120 beats per minute (bpm), and the obtained images were reconstructed using conventional algorithm (CA) and MCA. We compared the subjective image quality of coronary arteries using a four-point scale (1, excellent; 2, good; 3, fair; 4, poor) and measurement accuracy using measurement errors of the minimal luminal diameter (MLD) and minimal luminal area (MLA). Results: Compared with CA, MCA significantly improved the subjective image quality at HRs of 110 bpm (1.3 ± 0.3 vs. 1.9 ± 0.8, p = 0.003) and 120 bpm (1.7 ± 0.7 vs. 2.3 ± 0.6, p = 0.006). The measurement error of MLD significantly decreased on using MCA at 110 bpm (11.7 ± 5.9% vs. 18.4 ± 9.4%, p = 0.013) and 120 bpm (10.0 ± 7.3% vs. 25.0 ± 16.5%, p = 0.013). The measurement error of the MLA was also reduced using MCA at 110 bpm (19.2 ± 28.1% vs. 26.4 ± 21.6%, p = 0.028) and 120 bpm (17.9 ± 17.7% vs. 34.8 ± 19.6%, p = 0.018). Conclusion: Motion-correction algorithm can improve the coronary artery image quality and measurement accuracy at a high HR using an anthropomorphic dynamic heart phantom and 256-detector row CT scanner.

Lung cancer and insurance medicine (폐암과 보험의학)

  • Lee, Sin-Hyung
    • The Journal of the Korean life insurance medical association
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    • v.31 no.1
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    • pp.34-36
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    • 2012
  • Lung cancer such as small cell lung cancer(SCLC) and non small cell lung cancer(NSCLC) have high mortality rate, so, we insurance doctors have little interest in their risk. But nowadays there's a lot of development in targeted therapy of NSCLC. Screening by CT scanning and early resection strategy also shows better prognosis. It is helpful for underwriters and insurance doctors to review the current development of targeted therapy of NSCLC and estimation of extra-risk of early lung cancer. The preferred treatment option for patients whose tumors contain EGFR-activating mutations are one of the EGFR-directed tyrosine kinase inhibitors, such as gefitinib or erlotinib. In patients with NSCLC whose tumors harboured an ALK rearrangement, there was 61% objective response rate to crizotinib in the phase 1 study. The median survival progression-free survival was 10 months. Mortality analysis of early lung cancer who were detected by CT screening, MR of 105% and EDR of 1‰ were calculated.

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