• Maxillofacial Plastic and Reconstructive Surgery
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• v.28 no.3
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• pp.193-201
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• 2006

Squamous cell carcinoma(SCC) of head and neck(SCCHN) is the sixth most common human malignant tumor. However, despite advances in prevention and treatment of SCC, the five-year survival rates for patients remain still low. To improve the outcome for patients with SCCHN, novel treatment strategies are needed. Overexpression of the epidermal growth factor(EGF) and activation of its receptor(EGFR) are associated with progressive growth of SCCHN. Vascular endothelial growth factor(VEGF) signaling molecules are related with neoangiogenesis and vascular metastasis of SCC. In this study, we determined the therapeutic effect of AEE788(Novartis Pharma AG, Basel, Switzerland), which is a dual inhibitor of EGFR/ErbB2 and VEGFR tyrosine kinases, on human oral SCC. At first, we screened the expression of EGFR, c-ErbB2(HER-2) and VEGFR-2 in a series of human oral SCC cell lines. And then we evaluated the effects of AEE788 on the phosphorylation of EGFR and VEGFR-2 in a oral SCC cell line expressing EGFR/HER-2 and VEGFR-2. We also evaluated the effects of AEE788 alone, or with paclitaxel(Taxol) on the oral SCC cell growth and apoptosis. As a result, all oral SCC cells expressed EGFR and VEGFR-2. Treatment of oral SCC cells with AEE788 led to dose-dependent inhibition of EGFR and VEGFR-2 phosphorylation, growth inhibition, and induction of apoptosis. Moreover, AEE788 sensitizes the cells to paclitaxel-mediated toxicity and apoptosis. These data mean EGFR and VEGFR-2 can be reliable targets for molecular therapy of oral SCC, and therefore warrant clinical use of EGFR/VEGFR inhibition in the treatment of patients with recurrent or metastatic oral SCC.

• Journal of the Korea Convergence Society
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• v.7 no.3
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• pp.35-44
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• 2016

The purpose of this study is to examine the theoretical background of art make-up and surrealism in depth and shed new light on creative thoughts coming through application of Depaysement and various kinds of expression realized through art make-up, where art and make-up are incorporated. The study method is to conduct prior research followed by a theoretical study of the concept and techniques of Surrealistic Depaysement and theoretical background of art make-up through specialized books and internet sources and then to create 4 artworks representing characteristics of Depaysement technique categorized in dual image, fusion of heterogeneous objects, modification and conversion, and change of space. This examination resulted in first, a foundational ground for fusion and use of art and make-up sectors by creating a realm of expression based on creativity through incorporation of art and makeup and second, a sense of freshness and unfamiliar-ness by creation of an image in a completely unfamiliar space. Therefore, the researcher sets a direction for ways to come up with new ideas and expand the realm of expression and hopes that the art-makeup does not just become an aesthetic tool but turn itself as an art genre.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.12 no.6
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• pp.2595-2618
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• 2018

In this paper, we investigate secure communication with the presence of multiple eavesdroppers (Eves) in a two-tier downlink dense heterogeneous network, wherein there is a macrocell base station (MBS) and multiple femtocell base stations (FBSs). Each base station (BS) has multiple users. And Eves attempt to wiretap a macrocell user (MU). To keep Eves ignorant of the confidential message, we propose a physical-layer security scheme based on cross-layer cooperation to exploit interference in the considered network. Under the constraints on the quality of service (QoS) of other legitimate users and transmit power, the secrecy rate of system can be maximized through jointly optimizing the beamforming vectors of MBS and cooperative FBSs. We explore the problem of maximizing secrecy rate in both non-colluding and colluding Eves scenarios, respectively. Firstly, in non-colluding Eves scenario, we approximate the original non-convex problem into a few semi-definite programs (SDPs) by employing the semi-definite relaxation (SDR) technique and conservative convex approximation under perfect channel state information (CSI) case. Furthermore, we extend the frame to imperfect CSI case and use the Lagrangian dual theory to cope with uncertain constraints on CSI. Secondly, in colluding Eves scenario, we transform the original problem into a two-tier optimization problem equivalently. Among them, the outer layer problem is a single variable optimization problem and can be solved by one-dimensional linear search. While the inner-layer optimization problem is transformed into a convex SDP problem with SDR technique and Charnes-Cooper transformation. In the perfect CSI case of both non-colluding and colluding Eves scenarios, we prove that the relaxation of SDR is tight and analyze the complexity of proposed algorithms. Finally, simulation results validate the effectiveness and robustness of proposed scheme.

• International Journal of Internet, Broadcasting and Communication
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• v.9 no.2
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• pp.64-69
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• 2017

The abstract should summarize the contents of the paper and written below the author information. Use th In Wide-area Wireless Sensor Networks, network lifetime is short due to energy consumption due to transmission distance. To improve this, we divide the sensor field into layers and reduce transmission distance through multi-hop transmission. However, there is a problem in that the transmission rate drops because there is no Cluster Head in the layer, or the transmission distance increases due to the layer, and energy is wasted. There are DL-LEACH and EDL-LEACH as Protocols to improve this. DL-LEACH uses either single-hop transmission or multi-hop transmission depending on the situation. As a result, the transmission distance is optimized, thereby reducing energy consumption. In case of EDL-LEACH, it is proposed to improve the data rate in DL-LEACH. It is the same as DL-LEACH, but the Cluster Head is mandatory for all layers to improve the transmission rate. Although there is no Cluster Head for each layer, the transmission rate is improved, but the network life is shortened. In this paper, we try to improve the network lifetime while maintaining the EDL-LEACH transmission rate. The shortened network lifetime is due to Cluster Head overload near the base station. To improve this, the Cluster Head distribution method is improved and the network lifetime is improved.

• The Bulletin of The Korean Astronomical Society
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• v.38 no.2
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• pp.36-36
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• 2013

Globular clusters (GCs) are among the oldest stellar objects in the universe and provide valuable constraints on many aspects of galaxy evolution. GC systems typically exhibit bimodal color distributions the phenomenon of which has been a major topic in the area of GC research. GC color bimodality established a paradigm where scenarios to explain its origin require two GC groups with different formation origins. The GC division, asserted mainly by photometric color bimodality so far, has been viewed as the presence of two distinct metallicity subgroups within individual galaxies. In this study, we make use of spectroscopy of GC systems associated with two giant galaxies, M31 (the Andromeda) and M87 (NGC 4486), to investigate the GC bimodality and the underlying metallicity distributions. Recent spectroscopy on the globular cluster (GC) system of M31 with unprecedented precision witnessed a clear bimodality in absorption-line index distributions of old GCs. Given that spectroscopy is a more detailed probe into stellar population than photometry; the discovery of index bimodality may point to the very existence of dual GC populations. However, here we show that the observed spectroscopic dichotomy of M31 GCs emerges due to the nonlinear nature of metallicity-to-index conversion and thus one does not necessarily have to invoke two separate GC subsystems. We present spectra of 130 old globular clusters (GCs) associated with the Virgo giant elliptical galaxy M87, obtained using the Multi-Object Spectrography (MOS) mode of Faint Object Camera and Spectrograph (FOCAS) on the Subaru telescope. M87 GCs with reliable metallicity measurements exhibit significant inflection along the color-metallicity relations, through which observed color bimodality is reproduced from a broad, unimodal metallicity distribution. Our findings lend further support to this new interpretation of the GC color bimodality, which could change much of the current thought on the formation of GC systems and their host galaxies.

• Transactions of the Korean hydrogen and new energy society
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• v.28 no.2
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• pp.174-180
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• 2017

Recently, the world faces the environmental problem such as air pollution due to harmful gas discharged from car and abnormal climate due to the green-house gases increased by the discharge of $CO_2$. Compressed Natural Gas (CNG), one of alternative for this problem, is less harmful, compared to the existing fossil fuel, as gaseous fuel, and less carbon in fuel ingredients and carbon dioxide generation rate relatively favorable more than the existing fuel. However, CNG fuel has the weakness of slow flame propagation speed and difficult fast burn. On the other hand, hydrogen does not include carbon in fuel ingredients, and does not discharge harmful gas such as CO and HC. Moreover, it has strength of quick burning velocity and ignition is possible with small ignition energy source and it's has wide Lean Flammability Limit. If using this hydrogen with CNG fuel, the characteristics of output and discharge gas is improved by the mixer's burning velocity improved, and, at the same time, is possible to have stable lean combustion with the reduction of $CO_2$ expected. Therefore, this research tries to identify the characteristics of engine and emission gas when mixing CNG fuel and hydrogen in each portion and burning them in spark igniting engine, and grasp the lean combustion limit and emission gas characteristics according and use it as the basic data of hydrogen-CNG premixed engine.

• Journal of Sensor Science and Technology
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• v.21 no.6
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• pp.395-401
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• 2012

The bond strength of three types of $TiO_2$ coatings onto fluorine-doped $SnO_2$ (FTO) glass was investigated with the aid of a tape test according to ASTM D 3359-95. Transmittance was then measured using an UV-vis spectrophotometer in the wavelength range of 300 nm to 800 nm to evaluate the extent of adhesion of $TiO_2$ nanorods/nanoparticles on FTO glass. A sharp interface between the coating layer and the substrate was observed for single $TiO_2$ coating ($TiO_2$ nanorods/FTO glass), which may be detrimental to the bonding strength. In multicoating sample ($TiO_2$ nanorod/$TiO_2$ nanoparticle/$TiO_2$ nanoparticle/FTO glass), the tape test was not performed due to severe peeling-off prior to the test. On the other hand, the dual coating sample ($TiO_2$ nanorod/$TiO_2$ nanoparticle/FTO glass) showed minimum variation of transmittance (4%) after the test, suggesting that the topcoat adheres well with the FTO substrate due to the presence of the $TiO_2$ nanoparticle buffer layer. The use of a $TiO_2$ nanorod electrode layer with good adhesion may be attributed to the excellent dye sensitized solar cell performance.

• Journal of the Korean Society of Clothing and Textiles
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• v.38 no.1
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• pp.19-32
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• 2014

The Taekwondo uniform has remained consistent since it was officially designed in a V-neck form in 1976. Taekwondo is a martial art that emphasizes social etiquette; therefore, it is necessary to dress in a uniform that reflects Korean traditions and ancient oriental philosophy. However, the current official uniform has limitations in endowing traditionality and many usability problems. Thus, recognizing the problems raised with the uniform, the Kukkiwon (World Taekwondo Headquarters) developed a new style official uniform in 2011. This study is to endow traditional meaning to a new style uniform and proposes some design modifications that can convey a more traditional adequacy. The development of the new official uniform began with a specific plan for change from the existing uniform, this study as subsequent work is significant in that its endowment of symbolism and modification proposal is for the actual execution and global dissemination of traditional Taekwondo culture. The results of this study are as follows. First, we can endow Korea's traditional historicity and symbolism to the new uniform in form and colors. All contents of the design (in which the front side is open, the top is adjusted rightward, the rear length is shorter than the front length, comfort provided by side vents, dual collars for children's uniforms, and a belt) are adapted from the Korean traditional costume. Consequently, historicity can be endowed to the uniform. It is also confirmed that the traditional oriental philosophy including heaven and earth (天地), Yin-Yang (陰陽), and Five Elements (五行) can be endowed in the use of colors. Second, in order to project deeper historicity and symbolism to the form of the new uniform, this study proposes design modifications based on the selection as an item of Simui (深衣), a type of traditional clothing that contains a high symbolism similar to the Taekwondo uniform. It proposes giving shape to the practice of manners, the righteous life, and the straightforward mind by modifying the design of the uniform in the fish belly part of the sleeves, collars, back stitches, and side seams.

• Journal of Broadcast Engineering
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• v.18 no.3
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• pp.342-348
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• 2013

In this paper, a novel frame rate up conversion (FRUC) algorithm using adaptive extended bilateral motion estimation (AEBME) is proposed. Conventionally, extended bilateral motion estimation (EBME) conducts dual motion estimation (ME) processes on the same region, therefore involves high complexity. However, in this proposed scheme, a novel block type matching procedure is suggested to accelerate the ME procedure. We calculate the edge information using sobel mask, and the calculated edge information is used in block type matching procedure. Based on the block type matching, decision will be made whether to use EBME. Motion vector smoothing (MVS) is adopted to detect outliers and correct outliers in the motion vector field. Finally, overlapped block motion compensation (OBMC) and motion compensated frame interpolation (MCFI) are adopted to interpolate the intermediate frame in which OBMC is employed adaptively based on frame motion activity. Experimental results show that this proposed algorithm has outstanding performance and fast computation comparing with EBME.

• Journal of Fashion Business
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• v.2 no.1
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• pp.57-70
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• 1998

This study is aimed to research on the characteristics of domestic fashion magazines, and the problems and reforms of licensed magazines focused on the function of fashion magazines. As the result of study, the characteristics of domestic fashion magazines were as follows. 1) The inproportionte phenomenon of readership only concentrated on unmarried female readers in their 10' sand 20' s. 2) The lack of discrimination in magazine compilation. 3) The dual phenomenon of fashion magazines to distinguish the condition of magazines by the types of publication. 4) The role of magazines concentrated on information transmission and entertainment function. 5) The inproportionate phenomenon of publishers concentrated on domestic well-known magazine and paper companies. The problems of licensed fashion magazines found through practical grasp of the present condition are as follows. 1) Planning and compilation not to disclose the identity of each magazine. 2) Insufficiency of commentary articles. 3) Indiscreet planning and compilation of graphics. 4) Use of improper fashion terms and lack of explanation of specialized fashion terms. 5) Shortage and repetition of article materials. And the reform plans to the problems of licensed fashion magazines are as follows. 1) Subdivision and diversification of target market (readers' class). 2) Production of Korean view reflecting the world trend. 3) Expansion of commentary articles and commentary reports with objectivity and specialized character. However, these reform plans are not limited to licensed magazines, but may a basic methodology for improving the quality of domestic magazines.