• 한국환경과학회지
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• 제20권2호
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• pp.175-183
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• 2011

This study was conducted to survey the subjective symptoms of workers and users in selected 5 public facility groups(offices, performance halls, private crammers, wedding halls and indoor sports facilities), located in Seoul, Daejeon and Chungnam Province. Overall as subjective symptoms that were worse at public facilities than those usual, following responses appeared: I have a headache, My eyes are dry or feel irritated or itching, I feel eyestrain or my eyes are bloodshot, My nose was stuffy, I have a cough, I feel dry in the throat or inflammation happens, I feel oppressed in the breast or sometimes have difficulty in breathing, My skin gets dry, My skin is itching or has some spots, I feel like vomiting, I feel easily tired or sleep, I lose my concentration and I feel my memory is falling, I feel dizzy, I feel depressed, I feel being sharp and feel tension, I feel muscular pain or stiffness on shoulders, back and neck. Also, we compare with normal subjective symptoms scores and subjective symptoms scores in public facilities. The highest subjective symptoms score in at normal was my skin gets dry(2.35 points) and subjective symptoms score in public facilities was I feel eyestrain or my eyes are bloodshot(2.61 points).

• Journal of Chest Surgery
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• 제33권6호
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• pp.518-520
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• 2000

Epithelial-myoepithelial carcinoma is a rate low-grade malignant salivary neoplasm that usually occurs in the parotid gland but can also arise in minor salivary glands. We report a case of a primary epithelial-myoepithelial carcinoma of the lung neoplasm. The patient was 48-year-old women who presented with dry cough of 1 month duration. A right middle lobe endobronchial lesion was identified bronchoscopically. The bilobectomy of RML & RLL was performed, the pathologic result was epithelial-myoepithelial carcinoma.

• 대한암한의학회지
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• 제18권1호
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• pp.1-7
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• 2013

Objective : This study is purposed to report 2 cases of cancer patient whose symptoms related to radiation pneumonitis had been controlled with Saengmaek-san treatment. Methods : A 56-year-old female rectal cancer patient was prescribed with Saengmaek-san due to the symptoms which had developed 4 weeks after the completion of her radiotherapy session in both lungs. Her chief complaints were shortness of breath, dry cough and fatigue. Another case, 53-year-old male patient with hepatocellular carcinoma, had also developed symptoms of fatigue, weight loss and dry cough after his radiotherapy session in left upper lung zone. Radiological changes of both patients' chest X-ray suggested radiation pneumonitis. Results : Symptoms of the female patient were improved, especially shortness of breath, after Saengmaek-san treatment, without any aggravation in her chest X-ray result. However, infiltrative opacity in the left upper lung zone of the male patient was aggravated despite the improvement of his clinical symptoms. His remaining symptoms and radiological change were effectively controlled after steroid therapy. Conclusion : Seangmaek-san may be considered as a potential treatment for symptoms related to radiation pneumonitis with proper monitoring.

• 동의생리병리학회지
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• 제26권5호
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• pp.577-587
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• 2012

Warm disease: Any of various heat disease characterizer by rapid onset and shifts, pronounced heat signs, and a tendency to form dryness and damage yin. Exterior heat sign: exterior heat patterns are characterizer by pronounced heat signs, such as a red sore pharynx and a relatively red tongue with dry fur, the pulse is floating and rapid, cough and the production of thick white or yellow phlegm. If wind-heat evil exist in weifen, it becomes exterior syndrome, and a remedy about that is dispelling wind-heat but when wind-heat evil invades in nasal and throat part so the disease occurs, you need to add relieving sore throat worsens invades in lung it makes disharmony of diffuse in lungs. So a remedy about it is diffuse the lung. disharmony of diffuse in lungs makes metabolic disorder of qi and liquid and humor malfunction therefore it occurs cough and heat-phlegm syndrome. heat from weifen invades the whole of lungs and form lung heat. So a remedy about lung heat is clearing away lung heat, this lung heat makes inevitably bleed in lungs, therefore a remedy in this case is clearing the lung to stop bleeding, or moistening the lung. Exterior heat sign means that exterior syndrome coexists with heat syndrome and it means that a remedy of this syndrome need to mix prescriptions for relieving exterior syndrome and heat-clearing prescriptions to treat this syndrome.

• Toxicological Research
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• 제17권3호
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• pp.163-165
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• 2001

A patient,58 years of age, with suspected 0/l pneumoconiosis since 1993, complained of a dry cough and exertioning dyspnea for 6 months. He had worked in an asbestos company for more than 20 years from 1974. He was subsequently diagnosed with an interstitial lung disease during an annual special health check-up for asbestos workers. h chest X-ray showed an interstitial lung disease and high-resolution computed tomography (HRCT) showed a round opaque asbestosis with chronic hypersensitivity pneumonitis. A pulmonary function test indicated that the patient had a mild restrictive lung disease with FEV1 1.67 litters and 82% FEVl/FVC. The bronchoalveloar larvage fluid included many asbestos bodies, indicating previous exposure to asbestos. Transmission electron microscopy (TEM) using an energy dispersive X-ray analyzer (EDX) revealed many asbestos bodies consisting of mainly crocidolite fibers (6,071$\times$$10^6$fibers/g of dry lung). The patient had an unusually high asbestos content of 6,112$\times$$10^6$ asbestos fibers/9 of dry lung.

• 한국대기환경학회지
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• 제25권1호
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• pp.26-37
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• 2009

Recently rapid environmental changes due to desertification and industrialization in China make a threat to Korea, especially during Asian Dust Event (ADE). This study was aimed to compare symptoms and behaviors related to ADE between Korea and China. We conducted questionnaires on self-reported symptoms and behaviors before and during ADE. Korean and Chinese subjects were grouped into children, adults, and elderly by nation (n=791). Statistical analyses were performed by $X^2$-test, Fisher's exact test, t-test and chow's test for comparing differences between Korean and Chinese. We estimated the odds ratio for perceived symptoms during ADE by preventive behavior, using Generalized Estimation Equation (GEE). The study indicated that there were significant differences between symptoms in Korea and those in China such as cold, cough, and sore throat, especially in elderly. Preventive behaviors such as avoiding outdoor activity and wearing sunglasses were more often performed in China than Korea. However wearing mask was more often performed in Korea than China. After adjusting for age, sex, educational level, and smoking status, the odds ratio (OR) of dry cough symptom in Korea was significantly decreased by closing the windows and wearing a mask during ADE. In China, the OR of dry cough symptom was decreased by wearing a mask and avoiding outdoor activity. We found that China which had higher performance of preventive behavior showed lower prevalence of symptoms during ADE than Korea. Also preventive behaviors could affects prevalence of symptoms during ADE. This results suggest that preventive behavior. could reduce symptoms during ADE and there are needed for. more attentions to reduce a threat of ADE.

• Tuberculosis and Respiratory Diseases
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• 제64권5호
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• pp.347-355
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• 2008

연구배경: 특발성폐섬유증 환자의 전형적인 증상은 운동호흡곤란과 마른기침으로, 객담이 적은 원인에 대해서 아직까지 잘 알려져 있지 않다. Interferon-${\gamma}$ inducible protein-10 (IP-10)은 여러 호흡기질환과 관련되는데 폐 내로 염증을 유입시키는데 중요한 역할을 한다. 본 연구는 특발성폐섬유증 환자에서 객담이 적은 기전으로 IP-10이 연관성이 있는지에 대해 연구하였다. 방법: 특발성폐섬유증 환자를 대상으로 기관지폐포세척액에서 IP-10의 농도를 ELISA로 측정하였다. IP-10이 기도 점액소 발현에 미치는 영향을 간접적으로 알아보기 위해 NCI-H292 세포(점막표피모양 암종 세포주)에서 IP-10을 전처치한 이후 tumor necrosis factor-${\alpha}$ (TNF-${\alpha}$)로 자극하여 발현정도를 측정하였다. 이때 점액소 발현과 관련되는 기전으로 epidermal growth factor receptor-mitogen activated protein kinase (EGFR-MAPK)의 신호전달 경로를 알아 보았다. 결과: IP-10의 기관지폐포세척액내 농도는 특발성폐섬유증 환자가 건강 대조군에 비해 유의하게 높았다. IP-10의 전처치는 NCI-H292 세포에서 TNF-${\alpha}$ 유도 MUC5AC 점액소 발현을 감소시켰는데 이 때 EGFR-MAPK 신호전달 경로의 차단과 관련되었다. 결론: 특발성폐섬유증 환자의 적은 객담은 IP-10의 발현증가와 일부 관련 가능성이 있으며, 이때 IP-10의 작용은 MUC5AC 점액소 유전자 발현에 필요한 EGFR-MAPK 신호전달 경로의 차단과 관련될 것으로 생각한다.

• Tuberculosis and Respiratory Diseases
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• 제56권6호
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• pp.683-686
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• 2004

Pulmonary alveolar proteinosis is a rare disorder in which lipoproteinaceous material accumulates within the alveoli. We report a case of pulmonary alveolar proteinosis in a 41 year old female patient. She complained of a dry cough in the preceding 6 months. She presented symptoms of mild hypoxemia and diffuse infiltration at both lower lung fields. A milky fluid was obtained by bronchoalveolar lavage. We confirmed by light microscopic examinations of the lung tissues obtained by transbronchial lung biopsy. Through several follow-ups, the patients symptoms were mild.

• Journal of Medicine and Life Science
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• 제17권2호
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• pp.33-40
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• 2020

Coronavirus disease 2019 (COVID-19) is a respiratory tract infection caused by a newly emergent coronavirus, that was first recognized in Wuhan, China, in December 2019. Genetic sequencing of the virus suggests that it is a beta coronavirus closely linked to the SARS virus. This disease has non-specific symptoms such as fever, dry cough, sore throat, and gastrointestinal symptoms. This virus can transmit via aerosol and need to droplet precaution to prevent spreading in public areas. Most people with COVID-19 develop only mild or uncomplicated illness. However, about 20% patients require hospitalization, oxygen supply, and intensive care. There is no currently effective treatment available for COVID-19 unresponsive to supportive care. This is review about the recently published epidemiologic, and clinical features, diagnosis, treatment and prevention of COVID-19.

• Journal of Chest Surgery
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• 제9권1호
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• pp.41-43
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• 1976

Primary tumors of trachea are rather uncommon, and few cases of direct surgical excision were reported in the literature. Recently we had the opportunity to see a patient with a benign obstructing tumor of the trachea which was confirmed as fibroma. The patient has complained of intermittent dyspnea, especially during inspiratory phase, dry cough and wheezing of a strident character for last 8 years. Bronchoscopy or bronchography were not attempted because of severe dyspnea. Trachea tomogram revealed oval mass at the terminal trachea. The right posterolateral thoracotomy was performed. Tumor, $2.5{\times}1.7cm$ in size, was located at terminal trachea and removed through right lateral tracheotomy without difficulty. Postoperatively all the symptoms and signs disappeared.