• The Journal of the Korea Contents Association
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• v.19 no.1
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• pp.598-607
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• 2019

The side effects of using drugs can greatly threaten the health of the public. The reality is that there are very few reports of current side effects. This can be activated by linking adverse drug reactions reporting to the Drug Utilization Review (DUR) currently used by pharmacies. A study of the U.S. medication management system, where drug use assessment is activated, can find ways to activate adverse drug reactions reporting. In 'Pharm IT 3000', which is used as a medication management program in pharmacies, we examined how to enable reporting of adverse drug reactions. The literature study and research on actual program operation have found a convenient way to report side effects by linking the Pharm IT 3000 prescription preparation assessment to the item.

• Knowledge Management Research
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• v.19 no.4
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• pp.187-201
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• 2018

This paper explores the potential of Blockchain technology in enabling a panacea for health equity. Since Satoshi Nakamoto first described Blockchain technology in 2008 pseudonymous paper, that distributed ledger system is empowered and ranging from finance to law to another sector and beyond. Also impacting healthcare sector and life science. In other words, there are many usage cases being researched in healthcare and Blockchain has shown its considerable special side in recent years. But this paper aims to the distributed ledger that is the special side of Blockchain technology is potentially can panacea for some global health equity issues such as patient data, counterfeit drug and hospital payment management.

• Korean Journal of Clinical Pharmacy
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• v.31 no.1
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• pp.53-60
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• 2021

Objective: To gather the opinions of hands-on workers for successful introduction of the Development Safety Update Report (DSUR) according to a five-year comprehensive plan for clinical trial development [Ministry of Food and Drug Safety, 2019]. Methods: We conducted a survey on considerations that industry stakeholders may have related to the enforcement of the DSUR. A questionnaire was distributed among pharmacovigilance specialists from 13 pharmaceutical companies in South Korea on June 4, 2020. The questionnaire comprised two sections: 1) current status of the Drug Safety Data Management System and 2) considerations on the implementation and management of the DSUR. Results: All respondents have agreed the introduction of DSUR is inevitable for regulatory harmonization and safety of trial subject. However, most respondents (85%) felt concern about additional workload with DSUR implementation. They answered that format and operation system of DSUR should be harmonized with those of international standards and authorities need to minimize double burden due to related report. Conclusion: All respondents asserted that domestic DSUR should be harmonized with International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use (ICH) E2F guidelines. Respondents from global companies also suggested regulatory authorities allow DSUR written in English to replace Korean version considering their deadline for submission. Moreover, every respondent agreed regulatory authorities need delicate effort when implementing mandatory submission of DSUR to ensure that even small pharmaceutical companies with no experience in DSUR can comply with the system.

• Journal of Fisheries and Marine Sciences Education
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• v.29 no.2
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• pp.581-585
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• 2017

To strengthen the quality control of aquatic drugs, we compared the internal and external(EU, USA and Japan) aquatic drug classification systems and proposed a new aquatic drug classification system. Aquatic drugs are classified on the basis of their functional the functional characteristics or safety management degree of aquatic drugs. We suggested that the aquatic drugs can be categorized into 7 levels according to their functional characteristics and classified into 3 levels according to the safety management degree of aquatic drugs.

• The Journal of Internal Korean Medicine
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• v.29 no.4
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• pp.887-903
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• 2008

Objectives : We present some opinions to reduce the risk of herb-drug interactions through scanning "About Herbs" of the Memorial Sloan Kettering Cancer Center Website. Methods : We searched the Memorial Sloan Kettering Cancer Center Website of About Herbs and investigated herb-drug interactions. Results : There are 237 herbs and 196 drugs on About Herbs. 81.1% of herbs have fewer than 2 interactions listed.: 86.3% of drugs fewer than 3 interactions. Especially, 13 herbs were reported to have interactions with inclusive chemoagents on About Herbs. Only L-theanine has positive interaction with inclusive chemoagents. The others have negative interactions with inclusive chemoagents. 12 single chemoagents were reported to have interactions with some herbs. Especially tamoxifen-black cohosh, methotrexate-glutamin and aldesleukin-Huang Chi have positive interactions to increase the effects of the chemoagent. Conclusions : We should urgently create a risk management system of herb-drug interactions and take note of the risk of herb-drug interactions. We should build up systemic, evidence-based informations on popular herbs used by Korean cancer patients and herb-drug interactions in oncology like About Herbs.

• Biomolecules & Therapeutics
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• v.32 no.1
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• pp.1-12
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• 2024

Adverse drug reactions (ADRs) are an inherent aspect of drug use. While approximately 80% of ADRs are predictable, immune system-mediated ADRs, often unpredictable, are a noteworthy subset. Skin-related ADRs, in particular, are frequently unpredictable. However, the wide spectrum of skin manifestations poses a formidable diagnostic challenge. Comprehending the pathomechanisms underlying ADRs is essential for accurate diagnosis and effective management. The skin, being an active immune organ, plays a pivotal role in ADRs, although the precise cutaneous immunological mechanisms remain elusive. Fortunately, clinical manifestations of skin-related ADRs, irrespective of their severity, are frequently rooted in immunological processes. A comprehensive grasp of ADR morphology can aid in diagnosis. With the continuous development of new pharmaceuticals, it is noteworthy that certain drugs including immune checkpoint inhibitors have gained notoriety for their association with ADRs. This paper offers an overview of immunological mechanisms involved in cutaneous ADRs with a focus on clinical features and frequently implicated drugs.

• Proceedings of the Korea Information Processing Society Conference
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• 2012.11a
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• pp.1402-1405
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• 2012

데이터 품질의 패러다임 변화에 따라 기업에서는 효과적인 의사결정지원을 위한 정보서비스의 품질 관리가 중요하다. 본 연구에서는 설문조사를 통해 데이터 거버넌스 관점에서 행정기관 간 정보연계를 통해 민본 녹색 행정을 위한 '행정정보공동이용시스템'의 데이터 품질관련 현황을 분석하였다. 이와 관련하여 향후 정확하고 안전한 행정정보의 공동이용을 위한 정보서비스 품질관리체계 구축을 위한 대안으로서 데이터 거버넌스 관점의 행정정보 공유 데이터 품질관리체계 구축을 제시하는 바이다.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• v.16 no.4
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• pp.233-239
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• 2013

Drug intoxication in children and adolescents is not uncommon in Korea. But the tendency of intoxication is changing with some factors, such as national surveillance system, Naderism and increasing concern among physicians. But the death rate of intoxication among adolescents is increasing in spite of decreasing total death rate of intoxication among children and adolescents. Therefore the physician must be concerned about the basic management of intoxication and figure out the common toxic substance among children and adolescents.

• Journal of Food Hygiene and Safety
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• v.20 no.4
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• pp.253-257
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• 2005

This study was performed to develop management system of artificial flavor in Korea that considered the usage and management of artificial flavor within or outside (Europe, USA and JECFA) and to offer a yardstick for judgement and prevent from confusing when manufacture or import artificial flavoring substances. In questionnaire survey for flavoring manufacture form, ideal management system and others in companies related artificial flavor, the replier answered that artificial flavor was mainly used to drinks as water soluble from and that the countries exporting flavoring substances most frequently to Korea were Japan. Europe and America sequentially. On the basis of above results, we prepared the positive list (proposal) on about 1800 artificial flavoring substances for application to regulations in Korea Food Additives Code.

• Journal of electromagnetic engineering and science
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• v.18 no.1
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• pp.7-12
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• 2018

This article proposes an ultrahigh frequency band radio frequency identification (RFID) tag antenna for drug runout management that can be used in hospitals. The RFID tag antenna is designed to function as a sensor that alerts drug runout when a drug inside a drip chamber is completely consumed but does not work when a drug remains inside a drop chamber. A previously proposed 915 MHz dipole antenna, is too large to be attached to the drip chamber of a feeding bag. Moreover, the length of the dipole (L) should be increased for conjugate matching with an RFID chip. Therefore, the dipole antenna is downsized so that it can be attached to the drip chamber through a fine meander line structure coupling with a corrugate meander line. A transparent cover is added to enhance the grip force between the designed antenna and the drip chamber and to enable detachment. The dimensions of the completed antenna structure attachable to a drip chamber are 32.59 mm (height) and 13.5 mm (width). The gain reduction due to the decreased antenna length is enhanced. The fabricated antenna shows an average omni-directional read range of 10.65 m on a horizontal plane and has the function of sensing the presence of a drug.