• Title/Summary/Keyword: dosage of chemicals

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Selecting of Useful Chemicals Reducing of Leaf Blight on Job's Tears (Coix lachry-ma-jobi L. Var.)

  • Kwon, Byung-Sun
    • Plant Resources
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    • v.8 no.2
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    • pp.161-166
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    • 2005
  • This study was conducted evaluate the control effect of fungicides on control of Leaf blight, growth characteristics, and dry yield in the cultivation of Job's tears. All fungicides treated had no effect on the growth of Job's tears. The major fungicides were mancozeb Wp, $75\%$, chlorothalonil Wp, $75\%$, dithianon Wp, $43\%$, difenoconazole Wp, $10\%$, benomyl Wp, $50\%$, and propineb Wp, $70\%$. Dry seed yield were increased largely with chlorothalonil Wp, $75\%\;(33g/20\ell)$, fungicide than the other fungicides and control. All fungicides had no injury with standard dosage. On the other hand all fungicides had slight injury in the double dosage level for the Job's tears.

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TERATOGENICITY STUDY OF FOOD ADDITIVES CHEMICALS IN THE DEVELOPING CHICK EMBRYO

  • Lee, Yong-Soon;Park, Jae-Jun
    • Toxicological Research
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    • v.5 no.1
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    • pp.61-69
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    • 1989
  • To evaluate possible teratogenicity of food additives such as sodium propionate and monosodium glutamate, 300 haching eggs were subjected to potential mutagenicity assay by administration of low and high doses of the materials via york and air sac. The results are summarized as follows: 1. Mortality rate of chick embryo was increased significantly by dosage related in the group of sodium propiorate and monosodium glutamate when compared to placebo and non-treated group. 2. Frequency of embryo with malformation in treated group was not increased significantly when compared to placebo and non-treated group.

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Study on Inhalation Toxicity of Halogen Compound Using Rats (랫드를 이용한 할로겐 화합물의 흡입독성 연구)

  • Kim, Hyeon Yeong;Yu, Il Je;Lim, Cheol Hong;Chung, Yong Hyun;Maeng, Seung Hee;Lee, Jun Yeon;Lee, Sung Bae;Han, Jung Hee;Lee, Jong Yun;Lee, Yong Mok
    • Journal of Korean Society of Occupational and Environmental Hygiene
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    • v.10 no.2
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    • pp.109-123
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    • 2000
  • Inhaled halogen compound was examined through micronucleus tests and toxicity tests using SD (Sprague-Dawley) rats with repeated dosages for six hours a day, five days a week, during four weeks. In four-week repeated exposure, no specific sign caused by the $CF_3I$ compound was observed on the clinical symptoms, body weight variation, feed consumption, and urinalysis data in the testing groups with reference to the control group. In hematological and biochemical blood tests of the testing groups, the significant, but in their normal ranges, value dependencies of glucose, aspartate aminotransferase, alanine aminotransferase and etc., on the halogen carbohydride concentration was observed. In histo-pathological tests, no specific lesion or concentration dependent change due to the $CF_3I$ compound dosage was observed in both sexes of the female and male in the tested animals. But, micronucleus tests on marrow cells extracted from the tested animals which were repeatedly exposed in the $CF_3I$ compound during four weeks, the frequencies of micronuclei were significantly increased dose-dependently compared to the control groups.

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Intelligent Controller for Optimal Coagulant Dosage Rate in Water Treatment Process (정수장 약품 최적 주입률 결정을 위한 지능형 제어기 개발)

  • Lee, Ho-Hyun;Shin, Gang-Wook;Hong, Sung-Taek;Chun, Myung-Geun
    • Journal of the Korean Institute of Intelligent Systems
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    • v.25 no.4
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    • pp.369-376
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    • 2015
  • Chemicals are injected in order to remove a variety of organic substances contained in the water purification plant influent. It can be determined with measuring sedimentation turbidity 4~7 hours later, whether the chemical dosage rate is proper or not, which make the real-time feedback control impossible. In addition, manual operation in accordance with the Jar-Test carried out in the laboratory and the operator's experience may cause the experimental and human error by the changes of organic characteristics and water quality. Especially at night ad weekend, the rate have been determined only by the operator judgment owing to environment engineer's absence. Therefore, the decision of optimal chemical dosage rate using proposed intelligent control algorithm is expected to result in real-time injection and cost reduction.

Studies on Effective Period and Dosage for IBP Granules Application to Control Rice Blast, Especially Neck Blast (IBP입제(粒劑)의 최적(最適) 살포시기(撒布時期) 및 살포량(撒布量) 구명(究明)을 위(爲)한 조사연구(調査硏究) -특(特)히 수수(穗首)도열병(病) 방제(防除)를 중심(中心)으로-)

  • Park, Jong Seong;Kim, Hong Gi
    • Korean Journal of Agricultural Science
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    • v.10 no.1
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    • pp.84-89
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    • 1983
  • This study was attempted to find out the most effective period and dosage for IBP granules application to control rice blast, especially neck blast. The results obtained from the study are as follows; The most effective application period was about 15-20 days before heading. The most effective dosage was 4kg per 10a. The most effective control on rice blast was obtained when 4kg per 10a of IBP granules was applied about 15 to 20 days before heading. Therefore it should be emphasized that application period and dosage should be considered together, when applied by farmers. However, it may be necessary to apply chemicals at least one or two times before or after rice heading, since applications of IBP Ec. in July and IBP granules in August may not be enough to control rice blast completely.

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Evaluation of the Genetic Toxicity of Cyclopentane and Ammonium Nitrate - In vitro Mammalian Chromosomal Aberration Assay in Chinese Hamster Ovary Cells

  • Kim, Soo-Jin;Rim, Kyung-Taek;Kim, Jong-Kyu;Kim, Hyeon-Yeong;Yang, Jeong-Sun
    • Safety and Health at Work
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    • v.2 no.1
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    • pp.17-25
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    • 2011
  • Objectives: In this study, the in vitro mammalian chromosomal aberration (CA) assay was conducted to gain additional information concerning the hazards associated with the use of cyclopentane and ammonium nitrate. While these two chemicals had already been tested by many methods, they had not been studied in the CA test. Methods: The assay was performed using the ovarian infantile cell (CHO-K1 cell), by the direct method (-S9) and by the metabolic activated method (+S9 mix). Results: Using the direct method, the 7 dosages in a 48 hour treatment group did not show that the frequency of CA is proportion to the dosage addition. The frequency of CA is not proportion to the dosage addition for a 6 hour treatment using the metabolic activated method. Conclusion: From these findings, it was decided that the 2 chemicals do not induce chromosomal aberrations under the tested conditions.

PharmacoNER Tagger: a deep learning-based tool for automatically finding chemicals and drugs in Spanish medical texts

  • Armengol-Estape, Jordi;Soares, Felipe;Marimon, Montserrat;Krallinger, Martin
    • Genomics & Informatics
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    • v.17 no.2
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    • pp.15.1-15.7
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    • 2019
  • Automatically detecting mentions of pharmaceutical drugs and chemical substances is key for the subsequent extraction of relations of chemicals with other biomedical entities such as genes, proteins, diseases, adverse reactions or symptoms. The identification of drug mentions is also a prior step for complex event types such as drug dosage recognition, duration of medical treatments or drug repurposing. Formally, this task is known as named entity recognition (NER), meaning automatically identifying mentions of predefined entities of interest in running text. In the domain of medical texts, for chemical entity recognition (CER), techniques based on hand-crafted rules and graph-based models can provide adequate performance. In the recent years, the field of natural language processing has mainly pivoted to deep learning and state-of-the-art results for most tasks involving natural language are usually obtained with artificial neural networks. Competitive resources for drug name recognition in English medical texts are already available and heavily used, while for other languages such as Spanish these tools, although clearly needed were missing. In this work, we adapt an existing neural NER system, NeuroNER, to the particular domain of Spanish clinical case texts, and extend the neural network to be able to take into account additional features apart from the plain text. NeuroNER can be considered a competitive baseline system for Spanish drug and CER promoted by the Spanish national plan for the advancement of language technologies (Plan TL).

UV/H2O2 Advanced Oxidation of Photo Processing Chemicals in a UV-free Reflecting Reactor (사진현상폐수의 UV-자유반사 반응조에서의 UV/H2O2 고급산화처리)

  • Choi, Kyung-Ae;Kim, Young-Ju
    • Journal of Korean Society of Environmental Engineers
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    • v.22 no.2
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    • pp.241-249
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    • 2000
  • In this study, UV-catalyzed $H_2O_2$ oxidation and $H_2O_2$ oxidation to remove contaminants from photo processing chemicals were investigated at various conditions. Photo processing chemicals contains high concentrations of organic compounds and has very low biodegradability. Hydrogen peroxide is subjected to gradual decomposition as metastable substance. In the process, short-lived and highly reactive hydroxyl radicals are formed. The decomposition can be significantly accelerated by use of appropriate catalyst, such as ultraviolet radiation. The experiments were conducted in a UV-free reflecting reactor in batch and a high-pressure mercury lamp was used as UV source. Mixing, cooling and ventilation of the reactor were operated during experiments. In $UV/H_2O_2$ oxidation and $H_2O_2$ oxidation, the removal efficiencies of $COD_{Cr}$, TOC and chromaticity increased with the increase of $H_2O_2$ dosage and were higher in the controlled pH condition of 3 than in original pH condition of 8. In $UV/H_2O_2$ oxidation under the optimum condition of pH 8 and 1.3 stoichiometric $H_2O_2$ dosage, the removal efficiencies of $COD_{Cr}$, TOC and chromaticity were 47.5%, 75.0% and 91.5% respectively and $BOD/COD_{Cr}$ ratio was significantly increased from 0.04 to 0.21.

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Chemical Characteristics and Efficacy of Combined Pesticide Granules Formulated by Different Ways (제제방법별(製劑方法別) 혼합입제(混合粒劑) 농약(農藥)의 특성(特性)과 약효(藥效))

  • Oh, B.Y.;Park, Y.S.;Shim, J.W.;Kang, C.S.;Lee, H.R.
    • Applied Biological Chemistry
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    • v.29 no.1
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    • pp.90-95
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    • 1986
  • A comparative study of chemical characteristics, efficacy and relative merits of extruded and coated granules, containing fungicide and insecticide, was conducted under laboratory and field conditions. Probenzole (3-allyloxy-1,2-benzisothiazole 1,1-dioxide) and carbofuran (2,3-dihydro-2,2-dimethyl-7-benzofuranyl methyl carbamate) were chosen as toxicants for rice blast(Pyricularia oryzae) and brown planthopper (Nilaparvata lugens) control, respectively. Stability of active ingredients in coated granule was superior to the extruded one under accelerated temperature. Active ingredient dissolution of coated one into distilled water showed slow release pattern. Pesticide residues in rice (Oryzae sativa, Chucheongbyeo) shoot applied with extruded one at the dosage of 3kg/10a retained higher levels than those with coated one on two days after application, while the residue levels were a reversed tendency on eight days after application. Efficacy on rice blast exhibited minute differences between the granules, on the other hand efficacy on brown planthopper by coated one was of higher rank than that by extruded one. Production cost of the combined pesticide granule by coating method could be cut down by 6% as compared to extrusion method.

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Determination of Dosage of Flocculants for Paper Wastewater Treatment by Measuring Floc Strength (제지폐수의 플럭강도 측정에 따른 고분자응집제 주입량 결정)

  • Cho, Jun-Hyung;Kang, Mee-Ran
    • Journal of Forest and Environmental Science
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    • v.23 no.2
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    • pp.119-122
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    • 2007
  • Actually, about 45% of total costs for wastewater treatment in a papermaking mill is spent for sludge disposal and the cost of chemicals used to improve the dewaterability of sludge takes much part of it. In order to reduce sludge disposal cost and to improve the efficiency of sludge treatment, it is necessary to minimize the amount of water contained within the sludge and hence to improve the dewaterability of the sludge. The objective of this study was to elucidate the way of improving the dewaterability of sludge. Three types of wastewater from a tissue paper mill, a printing paper mill and a newsprint mill were used and two types of high molecular weight flocculants (anionic PAM and cationic PAM) were used to treat the wastewater. Dewaterability of sludge was evaluated by measuring floc strength.

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