• Journal of Oral Medicine and Pain
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• 제31권1호
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• pp.47-57
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• 2006

본 연구는, 표면열요법 중에서 널리 쓰이는 습열 요법(온습포)과 건열 요법(적외선 램프)이 전이부 표층부 혈류량과 피부온도에 미치는 영향을 평가하기 위해, 건강한 성인 20명(남 10명, 여 10명)을 대상으로 laser doppler flowmetry를 사용하여 표면열요법 적용전후의 피부 온도와 표층부 혈류량을 측정함으로써 다음과 같은 결과를 얻었다. 1. 온습포와 적외선 램프 모두에서 표층부 혈류량과 피부 온도는 적용전보다 적용후에 유의하게 증가하였다. 2. 표면열 요법 적용 후 표면 온도는 표면열 요법 적용 직후에, 표층부 혈류량은 표면열 요법 적용 4분 후에 가장 높게 나타났으며, 그 이후 꾸준히 감소하였다. 3. 표면열 요법 적용 후 증가된 표층부 혈류량은 적외선 램프에 비해 온습포에서 더 오랫동안 유지되었다. 4. 표면열 요법 적용 후 증가된 피부 온도는 두 요법 모두 60분간 유의성있게 증가된 상태로 유지되었으나, 적외선 램프 적용 후 증가된 피부 온도는 온습포에 비해 급격히 감소하였다. 5. 적외선 램프 적용 직후 여성이 남성보다 표층부 혈류량의 증가가 컸으나, 그 이후 차이가 점차 감소하여 20분 이후에는 성별에 따른 차이가 없었다.

• 방송공학회논문지
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• 제27권2호
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• pp.244-247
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• 2022

본 논문에서는 고속 이동환경에서 강건성을 향상시킬 수 있는 OTFS(orthogonal time frequency space) 시스템에서 주파수 및 시간영역에서의 선형 MMSE(minimum mean squared error) 필터를 이용한 디코딩 알고리즘과 강화된 Gauss-Seidel 알고리즘을 이용한 디코딩 알고리즘의 성능을 비교한다. 강화된 Gauss-Seidel 알고리즘은 잡음 증폭을 억제함으로써 비트 오류율 성능을 개선할 수 있다. 전산 실험 결과를 통해 주파수 영역에서 MMSE 필터를 이용한 디코딩 알고리즘은 수신기의 이동 속도가 높아짐에 따라 성능 열화가 발생하는 것을 확인할 수 있고, 강화된 Gauss-Seidel 알고리즘을 이용한 디코딩 방법은 120km/h 속도와 500km/h 속도를 가지는 채널 환경에 대해 주파수 영역 및 시간 영역에서의 MMSE 필터 디코딩 알고리즘에 비해 우수한 성능을 나타내는 것을 확인할 수 있다.

• 한국해양학회지:바다
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• 제26권2호
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• pp.63-81
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• 2021

이 연구에서는 2018년 늦은 봄철을 대상으로, 제주도내 위치한 제주와 보목 하수처리장의 해양방류구 주변 해역의 하수처리 방류수의 이동 특성을 파악하기 위하여 다층 유향·유속계 (Acoustic Doppler Current Meter; ADCP)와 지역규모 해양 수치모델의 가상 추적자 실험을 활용한 분석을 수행하였다. ADCP관측 결과에 의하면 두 하수처리장 모두 방류구 인근 해역의 해수 유동은 비조석 성분 보다 조석 성분이 컸고, 조류는 등수심선과 평행한 방향의 왕복성 운동이 지배적이었다. 조화 분석결과는 제주와 보목 하수처리장 해역 모두 반일주기 유속 성분이 우세한 혼합형 조석특성이 지배적이지만, 보목 하수처리장 주변의 유속 세기가 제주 하수처리장 유속의 50% 정도로 느리고, 조류의 회전성이 제주는 시계 방향, 보목의 경우 반시계 방향으로 지역적으로 차이를 보인다. 특히, 보목 하수처리장 방류구 주변해역은 상대적으로 느린 유속과 더불어 잔차류가 등수심선을 가로질러 연안으로 향하기 때문에 해안을 따라 오염물질이 집적되는데 유리한 환경이다. 고해상도 수치실험은 유속·유향 현장 관측 결과와 유사한 해수 유동 특성을 잘 모의하였으며, 오염물질의 이동확산을 파악하기 위한 추적자 실험을 통하여 잔차성분이 연안을 향하는 보목 하수처리장 연안에서 오염물질 잔류량이 상대적으로 높아질 수 있음을 제시하였다. 이러한 결과는 늦은 봄철에 보목 하수처리장 인근 해역이 상대적으로 약한 조류와 연안을 향하는 잔차성분의 영향으로 하수처리 방류수에 의한 연안 오염 가능성이 높은 환경임을 제시하는 결과이다. 퇴적유기물 조사에서도 보목하수처리장 인근 연안은 중간오염 단계를 보임으로써 조석 잔자류에 의한 연안 오염물질 축적과 그에 따른 연안환경오염의 가능성을 뒷받침하고 있다.

• 대한한의학회지
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• 제42권4호
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• pp.164-175
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• 2021

Objectives: The LI11 (Quchi) acupuncture point has always been included in the Seven acupoints for stroke; however, additional LI11 acupuncture research is needed. In this study, the effect of LI11 acupuncture on cerebral blood flow of the anterior cerebral arteries (ACA) and middle cerebral arteries (MCA) was investigated. Method: This study included 10 healthy young male subjects. Cerebral blood flow velocity and cerebrovascular reactivity were measured using transcranial Doppler sonography. Changes in hyperventilation-induced carbon dioxide (CO₂) reactivity and modified ACA and MCA blood flow velocity at 40 mmHg (CV40), blood pressure, and heart rate were observed before and after LI11 acupuncture treatment. Results: A statistically significant increase in contralateral anterior cerebral artery CO₂ reactivity (p=0.036) and decrease in contralateral middle cerebral artery CV40 (p=0.047) were observed. No significant difference in mean blood pressure was shown. A statistically significant increase in heart rate occurred after LI11 acupuncture; however, it was not clinically significant as there were negligible changes in the heart rhythm. Conclusions: LI11 acupuncture treatment could improve cerebral blood flow velocity. These results might be explained by regulating endothelium-dependent vessel dilation in the anterior cerebral artery region. Trial registration: This trial has been registered with Clinical Research Information Service, a service of the Korea Centers for Disease Control and Prevention: KCT0004494 (retrospectively registered). https://cris.nih.go.kr/cris/search/search_result_st01.jsp?seq=15359

• 동의생리병리학회지
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• 제17권1호
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• pp.64-70
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• 2003

Jaeumgenby-tang(JGT) have been used in oriental medicine for many centuries as a therapeutic agent of vertigo caused by deficiency of qi(氣) and blood(血). Effect of Aurantii Fructus(AF) take off the phlegm by promoting the circulation of qi, Gastrodae Rhizoma(GR) has effects treating for headache, vertigo by calming the liver and suppressing hyperactivity of the liver-yang(陽). And, I designed to investigate whether injection of JGT adding AFㆍGR extract(JGTAG) affects cytotoxicity in vitro, cerebral hemodynamics [regional cerebral blood flow(rCBF), pial arterial diameter(PAD), mean arterial blood pressure(MABP)] in normal and cerebral ischemia rats by MCA occlusion method. The changes of rCBF and MABP were determinated by laser-doppler flowmetry(LDF), and the change of PAD was determinated by video microscope and width analyzer. The results were as follows in normal rats; JGTAG was not cytotoxicity in brain cells. And JGTAG was significantly increased rCBF, PAD and MABP. This results suggest that JGTAG increased significantly rCBF by dilating PAD. And the results were as follows in cerebral ischemic rats; The changes of rCBF and PAD were increased stably by treatment with JGTAG(10mg/kg, i.v.) during the period of cerebral reperfusion, and pretreatment with propranolol and indomethacin were increased JGT AG induced increase of rCBF and PAD during the period of cerebral reperfusion. We suggest that JGTAG has an anti-ischemic effect through the improvement of cerebral hemodynamics.

• Restorative Dentistry and Endodontics
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• 제41권3호
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• pp.202-209
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• 2016

Objectives: The purpose of this study was to investigate the involvement of TRPA1 in the cinnamaldehyde-induced pulpal blood flow (PBF) change in the feline dental pulp. Materials and Methods: Mandibles of eight cats were immobilized and PBF was monitored with a laser Doppler flowmetry at the mandibular canine tooth. To evaluate the effect of cinnamaldehyde on PBF, cinnamaldehyde was injected into the pulp through the lingual artery at a constant rate for 60 seconds. As a control, a mixture of 70% ethanol and 30% dimethyl sulfoxide (DMSO, vehicle) was used. To evaluate the involvement of transient receptor potential ankyrin 1 (TRPA1) in PBF change, AP18, a specific TRPA1 antagonist, was applied into the pulp through the Class V dentinal cavity followed by cinnamaldehyde-administration 3 minutes later. The paired variables of experimental data were statistically analyzed using paired t-test. A p value of less than 0.05 was considered as statistically significant. Results: Administration of cinnamaldehyde (0.5 mg/kg, intra-arterial [i.a.]) induced significant increases in PBF (p < 0.05). While administration of a TRPA1 antagonist, AP18 (2.5 - 3.0 mM, into the dentinal cavity [i.c.]) caused insignificant change of PBF (p > 0.05), administration of cinnamaldehyde (0.5 mg/kg, i.a.) following the application of AP18 (2.5 - 3.0 mM, i.c.) resulted in an attenuation of PBF increase from the control level (p < 0.05). As a result, a TRPA1 antagonist, AP18 effectively inhibited the vasodilative effect of cinnamaldehyde (p < 0.05). Conclusions: The result of the present study provided a functional evidence that TRPA1 is involved in the mechanism of cinnamaldehyde-induced vasodilation in the feline dental pulp.

• 대한한의정보학회지
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• 제15권1호
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• pp.85-91
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• 2009

Objectives: We investigated the influence of the neck acupressure massage and the neck cream including korean herbal extract on the neck wrinkles and blood circulation. Methods: Korean female($37.47{\pm}3.66$ years, n=18) aged 30-39 years were participated in this study. We measured the neck wrinkles with PRIMOS(GFMesstechnik GmbH, Germany) and blood circulation of neck and facial skin with Laser Doppler Imaging-Periscan PIM II(Perimed AB, Sweden). Results: The neck wrinkles were significantly decreased after applying neck cream. But when with the neck acupressure massage, the neck wrinkles were decreased 2-fold than applying only the neck cream. The skin blood circulation was significantly increased on the neck and facial skin immediately after the neck acupressure massage. But this effect was not significantly different after 8 weeks Conclusions: This result suggests that the neck acupressure massage can improve the anti-wrinkles effect of the neck cream including Korean herbal extract.

• 대한조선학회논문집
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• 제37권1호
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• pp.26-39
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• 2000

예인수조와 캐비테이션 터널에서 레이놀즈 수가 프로펠러 단독 특성시험에 미치는 영향을 씨리즈 모형 프로펠러(날개수=4, $0.3{\leq}A_E/A_O{\leq}0.75,\;0.5{\leq}P/D{\leq}1.1$)에 대하여 실험적인 방법으로 조사하였다. 예인수조에서 프로펠러 단독 특성시험을 위한 시험조건으로 제15차와 17차 ITTC에서 추천한 레이놀즈 수($R_n{\geq}3.0{\times}10^5$)는 시험조건으로써 불충분함을 보였으며 적합한 시험조건 선정방법을 제안하였다. 예인수조와 캐비테이션 터널에서 프로펠러 단독특성들의 상호관계를 나타내는 상관계수($\kappa$)를 도출하였다. 프로펠러 축 주위에서 형성된 경계층 유동이 프로펠러 특성에 미치는 영향을 레이저 유속계를 이용한 계측에 의해 조사하였으며, 그 영향이 작지 않다는 것을 보였다.

• 대한한방내과학회지
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• 제30권2호
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• pp.438-449
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• 2009

Objectives: Deep vein thrombosis (DVT) is a common complication among stroke patients. The implication of DVT progressing into a fatal pulmonary embolism is one of the main reasons treatment cannot be delayed. However, when there is a contradiction for anticoagulants, such intracranial hemorrhage (ICH), it is difficult to determine the course of treatment. Our team reports a case with both acute DVT and ICH who improved with herbal medicine Hyulbuchuko-tang. Methods : A patient with a variety of thrombosis risk factors (atrial fibrillation, DVT, Cb-inf with intracranial hemorrhage due to thrombolytic complications) showed classic symptoms of DVT (pain, edema, discoloration), disorientation and chest discomfort. The patient was administered Hyulbuchuko-tang three times a day for 24 days without any anticoagulants. Conservative therapy including elastic stocking and leg elevation was co-administered. Laboratory tests and extremity vascular Doppler sonography were carried out 3 times during the treatment period. Results : After our treatment period, both popliteal vein DVT and calf vein DVT were not discovered by sonography, and thrombosis derived factors (eg. D-dimer, fibrinogen) decreased. There was no sign of edema or discoloration after treatment, and the patient no longer complained of leg pain, disorientation or chest discomfort. Conclusion : From these results, we suggest that there is a positive effect of Hyulbuchuko-tang on DVT. Hyulbuchuko-tang should be considered as a treatment option when western medical procedures are unavailable.

• Restorative Dentistry and Endodontics
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• 제21권1호
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• pp.366-374
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• 1996

The purpose of this study was to investigate whether D-myo-inositol-l,2,6-trisphosphate (PP56) can effectively antagonize vasoconstriction caused by neuropeptide Y in the dental pulp, and to understand involvement of neuropeptide Y in the regulation of microcirculation in the dental pulp with the aim of elucidating neurogenic inflammation. Experiments were performed on 7 cats anesthetised with sodium pentobarbital, and neuropeptide Y and a neuropeptide Y antagonist PP56 were injected close intra-arterially into the dental pulp. The probe of laser Doppler flowmeter was placed on the buccal surface of ipsilateral canine teeth to the drug administration and pulpal blood flow was measured. Intra-arterial injection of neuropeptide Y (1.3-$2.0\;{\mu}g$/kg) resulted in pulpal blood flow decrease of $37.73{\pm}5.73%$(mean${\pm}$SEM) (n=9). Intra-arterial injection of PP56(0.3 mg/kg) alone changed pulpal blood flow little by 1.03 % reduction. The effect of neuropeptide Y in the presence of PP56 resulted in significantly less decreases in pulpal blood flow ranging from $27.17{\pm}5.37$ to $16.63{\pm}3.48%$ from control as compared with neuropeptide Y alone(n = 13). In effect, PP56 attenuated pulpal blood flow caused by neuropeptide Y. Results of the present study have provided evidences that a non-peptide PP56 is capable of antagonizing vasoconstriction caused by neuropeptide Y in the feline dental pulp. In addition, they show functional evidences that neuropeptide Y plays an active role in modulating the microcirculation of the dental pulp.