• Title/Summary/Keyword: dominance effect

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Characterization of the Prolactin Receptor 3 (PRLR3) and Retinol-Binding Protein 4 (RBP4) Genes in the Birth Weight and Early Growth of Berkshire Pigs

  • Do, Chang-Hee;Lee, Dong-Hee;Cho, Byung-Wook
    • Journal of Animal Science and Technology
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    • v.53 no.3
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    • pp.185-193
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    • 2011
  • To investigate the influences of candidate genes on the birth weight and the early stages of life, genotyping of the prolactin receptor 3 (PRLR3) and retinol-binding protein 4 (RBP4) genes was performed in 156 and 141 Berkshire pigs, respectively. The frequency of both PRLR3 alleles A and a was 0.50. The frequencies of the RBP4 alleles B and b were 0.42 and 0.58, respectively. Neither locus was in Hardy-Weinberg equilibrium. No significant associations of the PRLR3 alleles with birth or weaning weights and of the RBP4 alleles with birth weight were observed. The proportions of the phenotype variances due to the genotypes of PRLR3 in the feeder weights was 4.0% and those of RBP4 in the weaning and feeder weights were 11.9 and 3.3%, respectively (P < 0.05). The dominance effect of PRLR3 and RBP4 on feeder weights was 2.40 and -1.86 kg, respectively (P < 0.01). The additive and dominance effects of RBP4 on weaning weights were 0.332 and -0.682 kg, respectively (P < 0.01). Even if no significant epistasis of PRLR3 and RBP4 was detected, a considerable trend of consistent positive epistasis estimates of AA/BB and Aa/Bb was observed for all traits. The results of this study may have a considerable impact on early-stage growth by both loci, and a selection strategy should be designed separately for each marker in Berkshire pigs.

Effect of Apical Ear Removal on Characters of Subapical Ear in Corn Inbreds (옥수수 백식계통의 상부이삭 제거가 하부이삭의 형질에 미치는 영향)

  • Lee, Myoung-Hoon
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.40 no.3
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    • pp.334-339
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    • 1995
  • Removal of apical ear after silking is a method to increase seed production in corn inbreds. Due to the phenomenon of apical dominance, the subapical ear would develope and produce seeds following the removal of the apical ear. This experiment was conducted to investigate the varietal difference in subapical ear development and seed production. Days to silking of subapical ears were delayed by about 4 days compared to normal apical ears. Cob length and filled ear length of subapical ears across seven inbreds tested were reduced by 21% and 36%, respectively. Those of inbred INV302 decreased less and subapical ear of inbred NC246 were barren, which incicated the varietal defferences. Number of kernel rows, kernels per row, and total kernels per ear also decreased. The mean reduction rates for those characters were 28%, 37%, and 47%, respectively. Weights of ears and kernels were reduced and showed different response among inbred lines. Coefficients of variations for cob and filled ear lengths, number of kernel rows and kernels were greater in subapical ears than in apical ears. Seed production of subapical ears was 40 ~ 80% of apical ears, depending on inbred lines when the apical ear is removed immediately after silking.

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Studies on the Combining Ability and Inheritance Agronomic Characters in Burley Tobacco (N. tabacum L. Cv. Burley) I. Heritability and Inheritance of Major Agronomic Characters (버어리종 담배(N.tabacum L. Cv. Burley)의 주요 형질에 대한 조합능력 및 유전에 관한 연구 제 1 보 각형질별 유전력 및 유전분석)

  • 조천준;민경수
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.28 no.4
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    • pp.488-496
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    • 1983
  • Narrow and broad sense heritabilities for the characters ranged from 0.1618 to 0.6914 and from 0.7494 to 0.9357, respectively, in F$_1$ hybrids of $5{\times}5$ full diallel crosses. Plant height and days to flowering had the highest heritabilities and yield and quality the lowest. Partial dominance was exhibited by plant height, number of leaves, leaf area per plant and days to flowering. Over dorminance was detected by leaf width and yield of cured leaf. Leaf length and quality would be considered being controlled by a complete dominance effect.

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Sandy Sediment Transport Mechanism on Tidal Sand Bodies, West Coast of Korea (해양(조수환경) 사립퇴적물의 이동기작에 관한 연구 - 한국 서해 만경강.동진강 하구 해역 -)

  • Yong Ahn Park;Hyo Jin Kang;Y.I. Song
    • The Korean Journal of Quaternary Research
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    • v.5 no.1
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    • pp.33-45
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    • 1991
  • Sand bars associated with strong tidal currents are well developed in the subtidal zone near the Kokunsan islands. Tidal currents measured at sand bar in the area show an asymmetry in magnitude between flood and ebb currents. At the southern flank of the sand bar the currents are flood-dominant whereas the currents are ebb-dominant at the northern flank. The asymmetry is more distinctive as the currents become stronger during spring tide. Moreover, the flood-dominance along the southern flank is stronger than the ebb-dominance along the northern flank. Thus the flood current is more affective to the sand bar. The sandy bottom sediment is mostly transported as bedload by the tidal currents. The magnitude asymmetry of the tidal currents results in a net sediment movement in one direction. The direction is onshore in the south and offshore in the north, which may result in a net counterlookwise rotation of the sands around the sand bar. However, the sand bar may migrate towards onshore due to the more affective flood current in the south. The irregular V-shaped outline of the sand bar in the south also seem to reflect the strong effect of flood current.

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Could A1 Aplasia or Hypoplasia Affect the Morphology and Rupture Risk of Anterior Communicating Artery Aneurysm?

  • Park, Sung Chan;Jung, Na Young;Park, Eun Suk;Kwon, Soon Chan
    • Journal of Korean Neurosurgical Society
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    • v.65 no.4
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    • pp.531-538
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    • 2022
  • Objective : Anterior communicating artery (Acom) aneurysm is one of the most common intracranial aneurysms, constituting approximately 30-35% of all aneurysm formation in the brain. Anatomically, the H-complex (the anatomic morphology of both A1 to A2 segments) is thought to affects the nature of the Acom aneurysm due to its close relationship with the hemodynamics of the vessel. Therefore, we investigated the relative risk factors of aneurysmal rupture, especially focusing on H-complex morphology of the Acom. Methods : From January 2016 to December 2020, a total of 209 patients who underwent surgery, including clipping and coiling for Acom aneurysm in our institution were reviewed. There were 102 cases of ruptured aneurysm and 107 cases of unruptured aneurysm. The baseline morphology of aneurysms was investigated and the relationship between the H-complex and the clinical characteristics of patients with Acom aneurysms was assessed. Results : Of the 209 patients, 109 patients (52.1%) had symmetrical A1, 79 patients (37.8%) had unilateral hypoplastic A1, and 21 patients (10.0%) had aplastic A1. The hypoplastic A1 group and the aplastic A1 group were grouped together as unilateral dominancy of A1, and were compared with the symmetrical A1 group. There was no significant difference in demographic characteristics and radiological findings of Acom aneurysms between two groups. However, when dichotomizing the patients into ruptured cases and unruptured cases, unilateral dominance of the A1 segment was associated with aneurysmal rupture with statistical significance (p=0.011). Conclusion : These results suggest that the unilateral dominance of the A1 segment does not have a significant effect on the morphology of Acom aneurysms, but contributes to aneurysmal rupture. Thus, we can better understand the effects of hemodynamics on Acom aneurysm.

Effect of Lactobacillus dominance modified by Korean Red Ginseng on the improvement of Alzheimer's disease in mice

  • Lee, Mijung;Lee, So-Hee;Kim, Min-Soo;Ahn, Kwang-Sung;Kim, Manho
    • Journal of Ginseng Research
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    • v.46 no.3
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    • pp.464-472
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    • 2022
  • Background: Gut microbiota influence the central nervous system through gut-brain-axis. They also affect the neurological disorders. Gut microbiota differs in patients with Alzheimer's disease (AD), as a potential factor that leads to progression of AD. Oral intake of Korean Red Ginseng (KRG) improves the cognitive functions. Therefore, it can be proposed that KRG affect the microbiota on the gut-brain-axis to the brain. Methods: Tg2576 were used for the experimental model of AD. They were divided into four groups: wild type (n = 6), AD mice (n = 6), AD mice with 30 mg/kg/day (n = 6) or 100 mg/kg/day (n = 6) of KRG. Following two weeks, changes in gut microbiota were analyzed by Illumina HiSeq4000 platform 16S gene sequencing. Microglial activation were evaluated by quantitative Western blot analyses of Iba-1 protein. Claudin-5, occludin, laminin and CD13 assay were conducted for Blood-brain barrier (BBB) integrity. Amyloid beta (Aβ) accumulation demonstrated through Aβ 42/40 ratio was accessed by ELISA, and cognition were monitored by Novel object location test. Results: KRG improved the cognitive behavior of mice (30 mg/kg/day p < 0.05; 100 mg/kg/day p < 0.01), and decreased Aβ 42/40 ratio (p < 0.01) indicating reduced Aβ accumulation. Increased Iba-1 (p < 0.001) for reduced microglial activation, and upregulation of Claudin-5 (p < 0.05) for decreased BBB permeability were shown. In particular, diversity of gut microbiota was altered (30 mg/kg/day q-value<0.05), showing increased population of Lactobacillus species. (30 mg/kg/day 411%; 100 mg/kg/day 1040%). Conclusions: KRG administration showed the Lactobacillus dominance in the gut microbiota. Improvement of AD pathology by KRG can be medicated through gut-brain axis in mice model of AD.

The Effect of Firm's Market Power on Job Creation in Korea (사업체의 시장지배력이 일자리 창출에 미치는 효과)

  • Kwon, Hye Ja;Cho, Woo Hyun
    • Journal of Labour Economics
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    • v.29 no.1
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    • pp.99-127
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    • 2006
  • This paper examines the effect of the market power of firms in the product market on job creation, job destruction and net job growth. It uses the reconstructed establishment data in the Korean Annual Mining and Manufacturing Survey between 1982 and 2002. This paper shows that job creation has continuously declined since the late 1980s and the decline is common for both market-dominant and competitive firms. The effect of market dominance on job creation is negative, controlling the firm-characteristics variables such as firm size and firm age.

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Moderating Effect of Luxury Value Perceptions in the Relationship between In-Store Emotions and Perceived Brand Luxury

  • Lee, Eun-Jung;Kim, Hanna
    • Journal of the Korean Society of Clothing and Textiles
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    • v.40 no.1
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    • pp.81-96
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    • 2016
  • The meaning of luxury varies by individuals. The differing luxury perceptions should influence the way individuals react to relevant marketing programs for luxury. Limited research exists on the topic despite interest in luxury segmentation and consumer-oriented values for luxury in marketplaces. Referring to the conceptual framework by Wiedmann et al. (2007), we explored the moderation role of four dimensions of luxury value perceptions (LVP; financial, functional, individual, and social dimensions), in the relationship between in-store emotion and perceived brand luxury. A total of 218 U.S. consumers participated in our online survey using a hypothetical luxury store image. The results revealed the following: First, on the relationship between felt pleasure and perceived brand luxury (PBL), the financial dimension of LVP only showed a significant moderation effect. Second, the effect of felt arousal on PBL was moderated by the financial and social dimensions of LVP. Lastly, the individual dimension of LVP only moderated the relationship between felt dominance and PBL. Theoretical and managerial implications are suggested.

Characterization of Quantitative Trait Loci (QTL) for Growth using Genome Scanning in Korean Native Pig

  • Lee, H.K.;Choi, I.S.;Choi, B.H.;Kim, T.H.;Jung, I.J.
    • Reproductive and Developmental Biology
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    • v.28 no.2
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    • pp.107-112
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    • 2004
  • Molecular genetic markers were genotyped used to detect chromosomal regions which contain economically important traits such as growth traits in pigs. Three generation resource population was constructed from a cross between the Korean native boars and Landrace sows. A total of 193 F2 animals from intercross of F1 were produced. Phenotypic data on 7 traits, birth weight, body weight at 3, 5, 12, 30 weeks of age, live empty weight were collected for F2 animals. Animals including grandparents (F0), parents (F1), offspring (F2) were genotyped for 194 microsatellite markers covering from chromosome 1 to 18. Quantitative trait locus analyses were performed using interval mapping by regression under line-cross model. To characterize presence of imprinting, genetic full model in which dominance, additive and imprinting effect were included was fitted in this analysis. Significance thresholds were determined by permutation test. Using imprinting full model, four QTL with expression of imprinted effect were detected at 5% chromosome-wide significance level for growth traits on chromosome 1, 5, 7, 13, 14, and 16.

Diallel Analysis for Rice Allelopathic Potential against Barnyardgrass Assessed in Field Condition

  • Junaedi, Ahmad;Lee, Sang Bok;Chung, Ill Min;Kim, Kwang Ho
    • Korean Journal of Breeding Science
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    • v.40 no.1
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    • pp.8-14
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    • 2008
  • A complete diallel cross was performed to determine the inheritance of allelopathic potential and combining ability of six rice germplasm that showed different level of allelopathic potential against barnyardgrass. Parents and F1 of 30 crosses were assessed for allelophatic potential in field condition. Barnyardgrass (Echinochloa crus-galli (L.) Beauv. var. frumentaceae) was used for rice allelopathic potential indicator which was observed in height and shoot dry weight, then suppression percentage were calculated by comparing to barnyardgrass grown in control plot (no rice). It was found that general combining ability showed no significant effect, whereas specific combining ability and reciprocal effect were significant. Variance analysis confirmed that genetic control of allelopathic potential in rice against barnyardgrass was mostly directed by dominance gene effect. The dominant genes were associated with high allelopathic potential and recessive genes were associated with low allelopathic potential. Heritability in broad sense for barnyardgrass dry weight suppression was around 41%; whereas for barnyardgrass height suppression was 51%. However, heritability in narrow sense was very low. The finding suggests that accumulation of genes associated with allelopathic potential would be a strategy to develop promising varieties in reference with the specific combining ability of cross combinations.