• 말소리와 음성과학
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• 제13권3호
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• pp.65-70
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• 2021

This paper proposes a method for designing a large recording script for open domain English speech synthesis. For read-aloud style text, 12 domains and 294 sub-domains were designed using text contained in five different news media publications. For conversational style text, 4 domains and 36 sub-domains were designed using movie subtitles. The final script consists of 43,013 sentences, 27,085 read-aloud style sentences, and 15,928 conversational style sentences, consisting of 549,683 tokens and 38,356 types. The completed script is analyzed using four criteria: word coverage (type coverage and token coverage), high-frequency vocabulary coverage, phonetic coverage (diphone coverage and triphone coverage), and readability. The type coverage of our script reaches 36.86% despite its low token coverage of 2.97%. The high-frequency vocabulary coverage of the script is 73.82%, and the diphone coverage and triphone coverage of the whole script is 86.70% and 38.92%, respectively. The average readability of whole sentences is 9.03. The results of analysis show that the proposed method is effective in producing a large recording script for English speech synthesis, demonstrating good coverage in terms of unique words, high-frequency vocabulary, phonetic units, and readability.

• 한국가시화정보학회지
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• 제19권2호
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• pp.15-25
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• 2021

Numerical studies on the hydrodynamics of a freely falling rigid sphere in bounded and unbounded water domains are presented having investigation on the drag coefficient, normalized velocity, surface pressure and skin friction coefficient as a function of time. Two different conditions of the bounded and unbounded domains have been simulated by setting the blockage ratio. Four cases of bounded domains (B.R. = 1%, 25%, 45%, 55%, 65% and 75%) have been taken, whereas the unbounded domain has been considered with 0.01%. In the case of the bounded domain (higher values of B.R.), a substantial reduction in normalized velocity and increase in the drag coefficient have been found in presence of the bounded domain. Moreover, bounded domains also yield a significant increase in the pressure coefficient when the sphere is partially submerged, but the insignificant effect is found on the skin friction coefficient. In the case of the unbounded domain, a significant reduction in normalized velocity occurs with a decrease in Reynolds number (Re) and also increase in the drag coefficient.

• Journal of Plant Biotechnology
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• 제49권1호
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• pp.39-45
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• 2022

Conserved domains are defined as recurring units in molecular evolution and are commonly used to interpret the molecular function and biochemical structure of proteins. Herein, the ADP-glucose pyrophosphorylase (AGPase) amino acid sequences of three species of the Ipomoea genus [Ipomoea trifida, I. triloba, and I. batatas (L.) Lam. (sweetpotato)] were identified to investigate their physicochemical and biochemical characteristics. The molecular weight, isoelectric point, instability index, and grand average of hyropathy markedly differed among the three species. The aliphatic index values of sweetpotato AGPase proteins were higher in the small subunit than in the large subunit. The AGPase proteins from sweetpotato were found to contain an LbH_G1P_AT_C domain in the C-terminal region and various domains (NTP_transferase, ADP_Glucose_PP, or Glyco_tranf_GTA) in the N-terminal region. Conversely, most of its two relatives (I. trifida and I. triloba) were found to only contain the NTP_transferase domain in the N-terminal region. These findings suggested that these conserved domains were species-specific and related to the subunit types of AGPase proteins. The study may enable research on the AGPase-related specific characteristics of sweetpotatoes that do not exist in the other two species, such as starch metabolism and tuberization mechanism.

• 안보군사학연구
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• 통권1호
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• pp.155-190
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• 2003

The objective of this study is to provide basic information for planning and practicing social welfare services for married nurse officers serving in the Korean military. For such a purpose, this study identifies the difficulties which married nurse officers have faced and the necessary services which are supposed to alleviate them. The data were collected by sending a questionnaire to 114 married nurse officers from July 16 to August 10, 2001. The results of this study are as follows: First, the married nurse officers were relatively dissatisfied with such domains as child care and education, health, and housing. And among the thirty-four problems, the married nurse officers expressed the most serious dissatisfaction with the difficulty in attending the events held in child's school, lack of children's dormitory run by the military, difficulty in adjusting to the school due to frequent house-moving, and limited access to dental care. Second, the married nurse officers needed services in domains such as housing, child care and education, and health. Specifically, they wanted the military-run housing, child care facility within military hospitals, maternity leave for child care and education, extension of risk allowances, and support for BOQ. Third, with regard to the seriousness of problems as well as the priority of services, the married nurse officers gave higher priority to such domains as child care and education, health, and housing. These results indicate that married nurse officers were to the largest extent concerned with these three domains and that they had the urgent need for services relevant to those domains. The importance of routine need assessments as well as solutions to the family-related problems for married nurse officers is therefore suggested in this study.

• Asian Pacific Journal of Cancer Prevention
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• 제15권9호
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• pp.3933-3938
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• 2014

Background: Assessment of supportive needs is the requirement to plan any supportive care program for cancer patients. There is no evidence about supportive care needs of Iranian breast cancer patients. So, the aims of present study were to investigate this question and s predictive factors. Materials and Methods: A descriptive-correlational study was conducted, followed by logistic regression analyses. The Supportive Care Needs Survey was completed by 136 breast cancer patients residing in Iran following their initial treatment. This assessed needs in five domains: psychological, health system and information, physical and daily living, patient care and support, and sexuality. Results: Patient perceived needs were highest in the health systems and information (71%), and physical and daily living (68%) domains. Logistic regression modeling revealed that younger participants have more un-met needs in all domains and those with more children reported fewer un-met needs in patient care and support domains. In addition, married women had more un-met supportive care needs related to sexuality. Conclusions: The high rate of un-met supportive care needs in all domains suggests that supportive care services are desperately required for breast cancer patients in Iran. Moreover, services that address informational needs and physical and daily living needs ought to be the priority, with particular attention paid to younger women. Further research is clearly needed to fully understand supportive care needs in this cultural context.

• Asian Pacific Journal of Cancer Prevention
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• 제17권5호
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• pp.2459-2464
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• 2016

Background: Cancer treatments can have long-term physical, psychological, financial, sexual and cognitive effects that may influence the quality of life. These can vary from urban to rural areas, survival period and according to the type of cancer. We here aimed to describe demographics and psychosocial analysis of cancer survivors three to five years post-treatment in rural Australia and also assess relationships with financial stress and quality of life domains. Materials and Methods: In this cross-sectional study, 65 participants visiting the outpatient oncology clinic were given a self-administered questionnaire. The inclusion criteria included three to five years post-treatment. Three domains were investigated using standardised and validated tools such as the Standard Quality of Life in Adult Cancer Survivors Scale (QLACS) and the Personal and Household Finances (HILDA) survey. Included were demographic parameters, quality of life, treatment information and well-being. Results: There was no evidence of associations between any demographic variable and either financial stress or cancer-specific quality of life domains. Financial stress was however significantly associated with the cancer-specific quality of life domains of appearance-related concerns, family related distress, and distress related to recurrence. Conclusions: This unique study effectively points to psychosocial aspects of cancer survivors in rural regions of Australia. Although the majority of demographic characteristics were not been found to be associated with financial stress, this latter itself is significantly associated with distress related to family and cancer recurrence. This finding may be of assistance in future studies and also considering plans to fulfil unmet needs.

• 한국융합학회논문지
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• 제8권12호
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• pp.235-241
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• 2017

본 연구는 유아 영어교육에서 유아의 음소인식과 음철법 향상을 위한 학습 효과를 극대화하기 위해 유아의 학습에 대한 흥미와 동기부여에 유용한 교육 자료를 연구하고 그 효용성을 검증하는 데 목적이 있다. 스토리 캐릭터 파닉스를 활용한 수업이 유아영어의 음소인식과 음철법에 미치는 영향을 검증하고 스토리 캐릭터 파닉스 학습을 적용하여 효율적인 음소인식과 음철법 능력 향상 방안을 제시하고자 한다. 본 연구는 충청남도 G시 S유치원 유아 24명을 실험집단과 비교집단으로 선정하여 2016년 3월부터 5주간 주3회 30분, 총 15차시로 실시했다. 스토리 캐릭터 파닉스가 음소인식과 음철법에 미치는 영향을 분석한 결과는 다음과 같다. 첫째, 실험집단과 비교집단은 동질집단으로 15차시에 걸친 수업 후, 스토리 캐릭터 파닉스를 활용한 집단의 음철법과 음소인식 영역의 점수가 통계적으로 유의미하게 높았다. 둘째, 유아들은 스토리 캐릭터 파닉스로 활용한 수업을 통해 학습 흥미도가 높아진 것을 알 수 있었다.

• Journal of Information Technology Applications and Management
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• 제27권1호
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• pp.125-145
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• 2020

We explore technology ecosystem of smart surgical medical system by analyzing patent data applied for in Korea and Japan. First, a review of trends of patent application by country/technological domain show that there exist a minority of technology domains focused on R&D, which represent their trends have been increasingly active. Also, while a number of Japanese firms mainly consist of the patent market of Japan, in case of the Korean market, a few universities, SMEs, and foreign firms are found to be the main applicants. As a result of the network analysis with the links as the relations of co-patenting, the relationships, which are active of convergence and knowledge spillover among the heterogeneous technology domains within each market, as well as the technology domains, which are the most active in international cooperation among each homogeneous domain, could get derived and visualized in the ecosystem. In addition, the technology domains in each patent market with leading locations, roles, and influence in the network can also be identified through the centrality analysis. In this study, the analysis for technology competitiveness are carried out focusing on patent activity and patent impact. The results denote that across all domains, the Japanese market may possess higher patent activity and patent impact compared to the Korean market. In consequence, we derive the position map for comparison by country and technology domain from a perspective considering comprehensively the multi-dimensional attributes based on the results of both network analysis and technology competitiveness.

• Genomics & Informatics
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• 제13권1호
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• pp.15-24
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• 2015

Fatty acid synthase (FASN, EC 2.3.1.85), is a multi-enzyme dimer complex that plays a critical role in lipogenesis. This lipogenic enzyme has gained importance beyond its physiological role due to its implications in several clinical conditions-cancers, obesity, and diabetes. This has made FASN an attractive pharmacological target. Here, we have attempted to predict the theoretical models for the human enoyl reductase (ER) and ${\beta}$-ketoacyl reductase (KR) domains based on the porcine FASN crystal structure, which was the structurally closest template available at the time of this study. Comparative modeling methods were used for studying the structure-function relationships. Different validation studies revealed the predicted structures to be highly plausible. The respective substrates of ER and KR domains-namely, trans-butenoyl and ${\beta}$-ketobutyryl-were computationally docked into active sites using Glide in order to understand the probable binding mode. The molecular dynamics simulations of the apo and holo states of ER and KR showed stable backbone root mean square deviation trajectories with minimal deviation. Ramachandran plot analysis showed 96.0% of residues in the most favorable region for ER and 90.3% for the KR domain, respectively. Thus, the predicted models yielded significant insights into the substrate binding modes of the ER and KR catalytic domains and will aid in identifying novel chemical inhibitors of human FASN that target these domains.

• 한국사회복지학회:학술대회논문집
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• 한국사회복지학회 2004년도 춘계학술대회 자료집
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• pp.365-382
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• 2004

The purpose of this study was to explore the concepts of health among people with mobility disabilities in order to develop a new holistic model of health and to identify implications for social work practice. A qualitative study based on face-to-face interviews with people with mobility disabilities was conducted. Nine consumers and nine social workers with mobility disabilities participated in the study. Social constructionism, heuristic paradigm, empowerment paradigm, and strength perspectives were used to form conceptual foundations to guide the study. Study participants' holistic descriptions of the concept of health encompassed five domains: biological/physical, mental/emotional, financial, relationships with others, and spiritual. Participants described health as harmony among these five domains. Harmony indicates that all five domains contribute to the concept of health, and that each domain is related to the others. Participants also viewed disability and health as an interconnected whole, not separate concept. The conceptual model developed in this study expands on the existing concepts of health by considering multiple factors at the personal and environmental levels, as well as interactions among the factors and between the levels. The personal level has five domains: biological/physical, mental/emotional, spiritual, financial, and relationships with others. The environmental level has also five domains: relationship with others, financial, social programs, social attitudes toward peoplewith disabilities, and physical environment. All factors under the personal and environmental levels also affect each other. The holistic concept of health for people with disabilities is not solely a part of the person, but rather is a function of the interaction between the person and their environment. The study demonstrated that people with disabilities have strength and resiliency, and health is an attainable goal for them, particularly when environmental and cultural barriers are addressed. The focus of social work practice should be the removal of those barriers encountered by their consumers with disabilities, as well as, the enhancement of internal factors that facilitate well-being.