• Proceedings of the Membrane Society of Korea Conference
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• 1996.06a
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• pp.177-189
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• 1996

Raverase osmosis or ultrafiltration systems have generally been regarded as hard to validate about WFI production. Though the Japanese and US Pharmacopoeias have allowed distillation and RO to be applied to WFI production process, only water stills, especially multiple effects have practically been employed for parenteral water production. On the other hand, the latest analysis has shown that even distillate contains such volatile organic matters as trihalomethanes and traces of heavy metals at a little higher concentration than supposed. The JP requires TOC to be monitored in WFI process based on RO or UF systems to control the concentration below 300ppb, but very few monographs or papers have so far been published about the concentrations of organic volatile matters in distillate. (See table 1-1) Therefore, this paper proposes a new applicable WFI systems based on the result of purified water analysis with some membranes used in the process. A well combined membrane system with other units could be expected to provide less amount of impurities in membrane-treated water than in distillate.

• Transactions of the Korean Society of Automotive Engineers
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• v.3 no.6
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• pp.112-122
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• 1995

As an alternative fuel producing less exhaust emissions, natural gas is of interest for use both in SI and CI engines. The potential of natural gas fuelled dual-fuel engine is considered high enough. However, much effort has to be made so that gaseous fuel is used efficiently with simultaneous minimum use of pilot oil. Hence, a simplified three-dimensional model, using a finite volume method in cylindrical coordinates, has been developed to facilitate an understanding of the dual-fuel combustion phenomena and to predict the complex interactions between the pilot distillate and natural gas. The computer model was calibrated by comparing it with the experimental results obtained from diesel engine like combustion bomb tests. In the pre-mixed natural gas combustion, the fuel burning was highly reliant on the injection condition and subsequent burning nature of the pilot distillate.

• Environmental Engineering Research
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• v.24 no.2
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• pp.347-353
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• 2019

Although membrane distillation (MD) has great promise for desalination of saline water sources, it is crucial to improve its thermal efficiency to reduce the operating cost. Accordingly, this study intended to examine the thermal energy efficiency of MD modules in a pilot scale system. Two different modules of hollow fiber membranes were compared in direct contact MD mode. One of them was made of polypropylene with the effective membrane area of $2.6m^2$ and the other was made of polyvinylidene fluoride with the effective membrane area of $7.6m^2$. The influence of operation parameters, including the temperatures of feed and distillate, feed flow rate, and distillate flow rate on the flux, recovery, and performance ratio (PR), was investigated. Results showed that the two MD membranes showed different flux and PR values even under similar conditions. Moreover, both flow rate and temperature difference between feed and distillate significantly affect the PR values. These results suggest that the operating conditions for MD should be determined by considering the module properties.

• The Journal of Korean Medicine
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• v.27 no.2 s.66
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• pp.196-210
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• 2006

Objectives : This study aimed to find the curative effect of Gamitongkyutang distillate in mice with allergic rhinitis. Metbods : Forty mice were divided into four groups: the normal group, the control group (allergic rhinitis elicited group), the sample I group (Gamitongkyutang treated group after allergic rhinitis elicitation) and the sample II group (distillate of Gamitongkyutang treated group after allergic rhinitis elicitation). Indexes of AR were investigated such as the histological changes of the nasal mucosa, the changes of eosinophil count, the changes of interleukin-4(IL-4) secretion in the intranasal mucosa, the alteration of inducible nitric oxide synthase(iNOS) mRNA expression and the distribution of the nuclear factor kappa B (NF-kB). ANOVA test was used for statistical analysis (p<0.05). Results : Loss of the cilium and the mucous secretion in the sample I and II groups was rare when compared to the control group. The segment of eosinophil was significantly decreased in the sample I and II groups when compared to the control group (p<0.05). A significant decrease of IL-4 mRNA expression was observed in the sample I and II groups when compared with the control group (p<0.05). Inhibition of iNOS induced by NF-kB p50 in the sample I and II groups was significantly superior to that in the control group (p<0.05). DGT and GT didn't affect AST and ALT. Conclusions : GT was superior to DGT in the IL-4 secretion, eosinophil levels and iNOS production. However, considering the difficulty in taking herbal medicine, the DGT has a meaningful curative effect in mice with allergic rhinitis.

• Journal of Korean Society of Environmental Engineers
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• v.36 no.6
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• pp.429-433
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• 2014

The objective of this study was to find optimum amount of bamboo smoke distillate (BSD) and reaction time (RT) for ammonia removal in food waste compost (FWC). BSD amount (30 to 90 mL BSD/600 g FWC) and RT (1 to 3 h) significantly affected the ammonia removal in FWC. Within the design boundaries, the optimum conditions for maximum ammonia removal (8.47 ppm $NH_3$/600g FWC) were 74 mL BSD/600 g FWC (0.123 mL BSD/g FWC) and 3 h RT. The BSD was effective on ammonia removal in FWC, rather than vinegar (p < 0.05). Our results proved a good potential of BSD to serve as an alternative deodorant for FWC.

• The Journal of Korean Medicine
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• v.37 no.1
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• pp.90-100
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• 2016

Objectives: The purpose of this study was to investigate the effect of Jeokbaekhaogwanjung-tang (JGT) distillate on the immune activity of spleen cells of aged rats. Methods: Spleen cells of 10w, 52w 72w old SD rats were cultured and treated with JGT distillate and the levels of IL-2, IL-4, IL-10 and IFN-${\gamma}$ were measured. Results: 1. The levels of IL-2 and IFN-${\gamma}$ in the spleen cells of 52w old rats were significantly decreased by JGT treatment. 2. The level of IFN-${\gamma}$ in the spleen cells of 72w old rats were significantly decreased by JGT treatment. Conclusion: These results suggest that Jeokbaekhaogwanjung-tang distillate has an immune regulative effect by way of suppressing the change of immune activity caused by aging in rats.

• Microbiology and Biotechnology Letters
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• v.27 no.3
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• pp.236-245
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• 1999

Andong Soju is a Korean traditional distilled liquor brewed with Nuruk which is cultured with wild microorganisms. To provide useful information for scientific production and systematic quality control of traditional distilled liquor, the effects of mixed culture of the alcoholic yeasts and saccharifying molds isolated from the Nuruk, and mashes on the flavor and sensory characteristics were investigated. Distillate from mashes cocultured with Saccharomyces cerevisiae and Hansenula anomala using Mucor Nuruk was compared with distillate from mashes brewed with Andong Nuruk and with distillate from plant fermented mashes to analyze their flavor characteristics. The volatile flavor compounds in distillates were analyzed by GC and GC-MS using direct injection, solvent extraction, and purge & trap methods. Alcohols such as 3-methyl-1-butanol, 2-methyl-1-propanol, 1-propanol, and 2-phenyl ethanol; aldehydes such as acetaldehyde and 2-furancar-boxaldehyde; esters such as ethyl ester of acetic acid, hexanoic acid, octanoic acid, decanoic acid; alkanes, alkenes, ketone, sulfur, and pyrone compounds were detected. Alcohols were chief components of flavor compounds. No significant difference in overall acceptability test was shown among three experimental groups(p<0.05), but Nuruk-like aroma, Kaoliangchiew-like aroma, sweet taste, and well rounded mouthfeel showed significant differences among them(p<0.05).

• Journal of the Korean Society of Food Culture
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• v.19 no.1
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• pp.52-60
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• 2004

This study was performed to investigate the effect of Lycii fructus beer on serum lipid profiles and antioxidant activity in rat Sprague-Dawley (SD) rats weighting about 190g were divided into the following 5 groups ; distillate water (Control), 5% ethanol in distillate water (Ethanol), commercial beer (CB), Lycii fructus beer (LFB) and 5% alcohol red wine diluted with distillate water (RW). Body weight, total food intake, FER and percent organ (liver, kidney) weight per body weight were not significantly changed by Lycii fructus beer drinking. After 6 weeks, serum total cholesterol, triglyceride and HDL cholesterol level were not significantly different. But, Lycii fructus beer intake tended to decrease serum triglyceride level and atherogenic index. Also, GOT and GPT levels were expressed lower than Ethanol group. There was not significantly different in hepatic glutatiione (GSH) content and glutathione-S-transferase (GST) activities among 5 groups. Lipid peroxidation in the hepatic was decreased by Lycii fructus beer intake. The results demonstrated that Lycii fructus beer was potential and effective antioxidant that can protect the decrease associated with alcohol.

• Korean Journal of Pharmacognosy
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• v.23 no.2
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• pp.106-114
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• 1992

The acute toxicity and the effect of steam distillate obtained from several plant mixtures (G-3) on the reactivation of brain, lung, and blood acetylcholinesterase (AChE) activity, and recovery from other toxic symptoms following intoxication by organophosphate pesticides were investigated in mice and mudfish. Administration of G-3 $(50{\sim}100\;ml/kg,\;i.p.)$ immediately or 30 min prior to Diazinon or Sumithion treatments, respectively, resulted in a significant reactivation of AChE activity in brain, lung, and blood, their potencies being almost equipotent to those of 2-PAM, one of well-known antidotes. G-3 itself exhibited almost no acute toxicity even at the highest dose employed, and without effect on the inhibition of hepatic drug metabolism function following organophosphate administrations. G-3 showed a significant diminution of the death rate in mudfish as well as in mice intoxicated by Diazinon.

• Journal of Microbiology and Biotechnology
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• v.34 no.2
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• pp.262-269
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• 2024

Panax ginseng has been widely applied as an important herb in traditional medicine to treat numerous human disorders. However, the inflammatory regulation effect of P. ginseng distillate (GSD) has not yet been fully assessed. To determine whether GSD can ameliorate inflammatory processes, a GSD was prepared using the vacuum distillation process for the first time, and the regulation effect on lipopolysaccharide-induced macrophages was assessed. The results showed that GSD effectively inhibited nitric oxide (NO) formation and activation of inducible nitric oxide synthase (iNOS) mRNA in murine macrophage cell, but not cyclooxygenase-2 production. The mRNA expression pattern of tumor necrosis factor alpha and IL-6 were also reduced by GSD. Furthermore, we confirmed that GSD exerted its anti-inflammatory effects by downregulating c-Jun NH₂-terminal kinase (JNK) phosphorylation, the extracellular signal-regulated kinase phosphorylation, and signaling pathway of nuclear factor kappa B (NF-κB). Our findings revealed that the inflammatory regulation activity of GSD could be induced by iNOS and NO formation inhibition mediated by regulation of nuclear factor kappa B and p38/JNK MAPK pathways.