• Korean Journal of Clinical Pharmacy
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• v.3 no.1
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• pp.55-60
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• 1993

For prevention of hospital infection, selection of adequate disinfectants by clinical pharmacist is very important role in hospital pharmacy and for performing this role, pharmaceutical, chemical and microbial knowledge of disinfectants and nosocomial microorganism are required to hospital pharmacists. Therefore, to make sure of guideline for choice of disinfectants, author clarifies the distinctive character of disinfectants which are supplied to clinical departments and wards from hospiatal pharmacy in Korea and arrange the specific attention for use of each disinfectants

• Journal of Korean Society of Occupational and Environmental Hygiene
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• v.31 no.2
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• pp.138-146
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• 2021

Objectives: This study aims to compare and evaluate the reduction efficiency of disinfectants used in the domestic meat processing industry to reduce bioaerosol exposure of meat industry workers and to use this as basic data for establishing work environment management measures. Methods: Thirteen disinfectants sold in South Korea were selected for evaluation and the bacterial reduction effect of the disinfectants was investigated. Bacterial suspension and surface disinfection tests were conducted to compare and analyze the antibacterial strength of the disinfectants. Pork carcasses, cutting boards, benches, and conveyor belts were selected for surface sterilization tests. Results: As a result of the bacterial suspension experiment test, all disinfectants had a bacterial reduction efficiency of more than 86%. Among them, the bacterial reduction efficiency of chlorine disinfectants was 99.93% on average. In the results of the pork carcass surface sterilization test, the rate of reduction of disinfectants made of quaternary ammonium compounds (QACs) was the highest. Tests of plastic cutting boards showed that chlorine disinfectants had the best sterilization effect. Experiments on stainless steel benches showed the best bacterial reduction efficiency for chlorine dioxide and QACs disinfectants. In the conveyor belt made of urethane, QACs disinfectants showed excellent sterilization effects. Conclusions: The study evaluated the disinfection power of disinfectants against bacteria occurring in domestic meat processing plants. All disinfectants were found to be effective in bacterial suspension experiments, and chlorine disinfectants were particularly effective. In surface sterilization experiments, sterilizing agents with QACs as the main ingredient were excellent.

• Korean Journal of Veterinary Service
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• v.32 no.4
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• pp.347-351
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• 2009

Bruella spp. involves a considerable danger of public health and farm animal industry. In this study, we assessed the disinfection efficacy of alkaline disinfectant solution and three commercial farm disinfectants (quaternary ammonium compound, sodium dichloroisocyanurate, potassium monopersulphate/sodium dichloroisocyanurate) against Brucella ovis. A bactericidal efficacy test by broth dilution method was used to determine the lowest effective dilution of selected disinfectants following exposure to test bacteria for 30 minutes at $4^{\circ}C$. Disinfectants and test bacteria are diluted with distilled water (DW), hard water (HW) or organic matter suspension (OM) according to treatment condition. Three commercial disinfectant showed excellent antimicrobial activity (up to dilution of $\times200$ in OM treatment). Alkaline disinfectant solution demonstrated favorable bactericidal efficacy against B. abortus (at dilution of $\times20$ in OM treatment). Three commercial farm disinfectants possess excellent efficacy against B. ovis. Alkaline disinfectant solution has lower potency than commercial farm disinfectant but could help to limit the spread of brucellosis.

• Journal of Korean Academy of Dental Administration
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• v.7 no.1
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• pp.50-55
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• 2019

The purpose of this study was to compare the number of bacteria before and after the use of surface disinfectants, demonstrate the bactericidal effect of surface disinfectants, and emphasize on the importance of surface disinfectants by recognizing the importance of infection control in dentistry. Chlorhexidine, hydrogen peroxide, ethanol, and chemical disinfectants are commonly used in dentistry. NaOCl was selected as the experimental group, and the bacterium test results obtained by comparing the table without surface sterilization as a control group showed that all disinfectants had an effective bactericidal effect (p<0.05). In the growth inhibition test comparing the experimental and control groups, all results were 100%, proving the effectiveness of surface disinfectants. The results showed that all surface disinfectants preferred and used by medical institutions were effective. Therefore, all surface disinfectants used in the experimental group were effective for surface disinfection for infection control. Dental clinicians should be aware of the necessity of disinfection of surfaces, such as table, chairs, and unit chairs, and make an active effort to ensure that both clinicians and patients are safe from infection.

• International Journal of Industrial Entomology and Biomaterials
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• v.6 no.2
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• pp.191-196
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• 2003

Silkworm body and rearing seat disinfection is an integral part of effective silkworm rearing as it prevents the spread of various diseases through secondary contamination in the rearing bed. Many bed disinfectants are recommended by various research institutes in India. In the present study, eight bed disinfectants viz., Vijetha, Labex, Resham Jyothi, Sanjeevini, Suraksha, Reshamkeet Oushadh, Dithane M45 and Captan recommended by various Sericultural Research Institutions in the country against the spread of common diseases of silkworm were tested to determine their comparative efficacy. For the study, all the treatment batches were introduced with fixed number of specific diseased larvae so as to maintain a constant source of pathogen in the bed and then followed by treatment with respective bed disinfectants. Percent mortality/infection due to each disease was recorded to determine efficacy of bed disinfectant treatment against respective disease. The results show that all the bed disinfectants tested have considerable efficacy against the spread of various diseases in the rearing bed. However, Vijetha was distinctly superior in its efficacy against all four major diseases of silkworm. The study emphasize the role of bed disinfectants in silkworm rearing and the fact that they should be judiciously selected based on the efficacy of the bed disinfectant and the type of disease prevalent in a particular season and area.

• Journal of Korean society of Dental Hygiene
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• v.7 no.4
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• pp.455-470
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• 2007

The usage of appropriate disinfectants is essential for infection control in dental hospitals, dental clinics. Inadequate use of disinfectants is the cause of human or environmental toxicity and is a waste of cost. This study was aimed to assess the level of knowledge on the disinfection and chemical disinfectants among dental workers in dental hospitals, dental clinics. It's ultimately intended to serve as a basis for the preparation of more effective, appropriate educational programs on the disinfection and manuals on the use of disinfectants for dental workers. This study enforced a questionnaire with 184 dental workers employed in dental hospitals, dental clinics from 15 Aug. to 15 Sep. 2007, in the area of Daejeon. The obtained result were as follows; 1. The population sociological feature of dental hospital and dental clinic showed that significant differences of dental service career(pM0.039). Dental service career of dental workers shows; below 3 years 42.9%, 4~6 years 34.7%, more than 7 years 22.4% in dental hospitals, below 3 years 30.4%, 4~6 years 26.7%, more than 7 years 43.0% in dental clinics(pM0.039). 2. The average score of dental workers knowledge in 'Critical item soaks in high-level disinfectants for 20minutes was 2.73V0.49 point, got from knowledge of dental instrument is appropriate to immerse before sterilization in the dental device disinfection(pM0.002). 3. In the general disinfection which it follows in education experience of chemical disinfectants direction for use, 'Direction for use by Spaulding process classification' responded that the correct answer was the education experience dental workers 60.0%, the education non-experience dental workers 39.5%(p=0.026). 4. In the dental device disinfection which it follows in education experience of chemical disinfectants direction for use. 'High level disinfection is not applied for the non-critical items and equipment' responded that the education experience dental workers 49.2%, the education non-experience dental workers 31.9%(pM0.045), 'Semi-critical items is applied same method in presence of the infection disease which it acts responded that the education experience dental workers 44.6% answer back, the education non-experience dental workers 24.4%(pM0.017). 5. 'A hand disinfectants of anticeptics have effect' the education experience dental workers 78.5% answer back, the education non-experience dental workers 52.9%(pM0.003). 1t uses with hand disinfectants when the instruments which be imbrued and patient contact', the education experience dental workers 78.5% answer back, the education non-experience dental workers 62.2%(pM0.026), 'Boric acid solution uses for the skin disinfectants the education experience dental workers 52.3% answer back, the education non-experience dental workers is 37.0%(pM0.016), 'Gluconate have effective difference which it follows in chemical disinfectant consistency and the solution type' education experience dental workers 72.3% answer back, education non-experience dental workers 47.9%(pM0.004). 6. The education experience dental workers were appeared higher than the education non-experience dental workers in knowledge of the disinfection and chemical disinfectants. Consequently system and the specialty education which is standardized continuously must be provided to all dental workers.

• Journal of Environmental Health Sciences
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• v.10 no.1
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• pp.13-20
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• 1984

The hospital wastewaters have to be so disposed as to prevent disease and to protect water resources from hazardous substances disinfectants, medicines, and chemicals. Polyvinylpyrrolidone-iodine complex (povidone-iodine) is widely used in the hospital as one of disinfectants. This study was carried out to manifest the effect of disinfectants in growth of activated sludge in treatment of the hospital wastewater by the activated sludge process. The results are as follow. 1. An average water quality of the hospital wastewater showed 7.2 in pH, 3.2 ppm in DO, 293.3 ppm in SS, 96.0 ppm in BOD, 151.1 ppm in COD, 0.4 ppm in povidone-iodine, 0.5 ppm in phenols, 5.4 ppm in surfactants, 1.6 ppm in o-phosphate, 4.6 ppm in $NH_3-N, 249\times 10^4$ counts/100 ml in coliform group organisms, and $1,369\times 10^2$ counts/ml in general counts of bacteria. And wastewater amounts discharged per bed was calculated 70 l/d/bed. 2. In batch culture activated sludge process, each of cresol and povidone-iodine was not effected in less than 0.1 ppm concentration, but the more concentration, the more inhibit the growth rate of activated sludge. In the mixture of two disinfectants, the growth was more inhibited the effect of single disinfectants. So that this reaction is considered as addition effect of two disinfectants. 3. The removal rates of the disinfectants-by continuous culture activated sludge process were 77.6% in 0.4 ppm povidone-iodine, and in BOD was 85.6%. 4. It is desirable that the hospital wastewater is planed in order to be discharged to two system separately, sewer from life system and wastewater from medical system. From those results, it has been concluded that the hospital wastewater has to be treated safely by the activated sludge process.

• Korean Journal of Veterinary Service
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• v.38 no.4
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• pp.211-220
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• 2015

Many chemical disinfectants are using to protect the foot and mouth disease (FMD) and avian influenza (AI) in Korea since 2000. This study was performed to confirm disinfective ability of commercialized chemical disinfectants and to investigate the sterilizing ability of E-ball as alterative to chemical disinfectants. 4 kinds of acidulant, 3 kinds of aldehyde, 1 kind of oxidizer and 300 g of E-ball were used in this study. Dilution rate of disinfective power of all chemical disinfectants were to 200 times. The sterilizing ability of aldehydes were better than the acidulant and oxidizer with Salmonella typhimurium. The sterilizing ability of E-ball treated solution was guessed due to the friction of E-ball deads. In the case of the friction of 2 beads of E-ball, Salmonella typhimurium was sterilizted on $1{\times}10^6/mL$ CFU in the E-ball treated solution. The E-ball treated solution had superior sterizing power compared with the chemical disinfectants in the bacteria of soil for antibacterial examination. E-ball treated solution has a possibility as the substitute of chemical disinfectants to protective the animal diseases contains FMD, AI.

• Journal of Korean society of Dental Hygiene
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• v.1 no.2
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• pp.243-250
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• 2001

To evaluate the effect of disinfectants for Alginate impression, several commercially available disinfectants were tested to Alginate model contaminated by Methicillin resistant Staphylococcus aureus. Alginate specimens were artificially contaminated by Staphylococcus aureus and soaking in four commercially available disinfectants for 1, 5, 10 minutes and colonies were counted for each case. Significant reduction of bacterial colony counts was noted after soaking in 0.5% and 0.05% sodium hypochlorite and after soaking in 2% glutaraldehyde, but not after soaking in Hypochlorus add. Commercially available sodium hypochlorite and glutaraldehyde were found to be effective disinfectants for Alginate impression. But hypochlorus add was not adequate disinfectant.

• Journal of Korean Biological Nursing Science
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• v.13 no.2
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• pp.125-133
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• 2011

Purpose: This study was performed to identify the affecting factors on hospital nurses' practice of disinfection focused on alcohol, chlorhexidine gluconate (CHG), and povidone iodine (PVI). Methods: The participants in this study were 196 nurses of 3 general hospitals and 2 upgrade general hospitals in 5 cities in Korea. Data were collected through self-reported questionnaires in January, 2011. The collected data were analysed by ANOVA, Pearson correlation and stepwise multiple regression using SPSS/WIN 18.0. Results: The subjects used alcohol and PVI daily for intravenous site care and surgical wound dressing respectively. The mean percentage of awareness in practicing main disinfectants were 80.0% and 72.5% respectively. The awareness and practice were highest in alcohol, but lowest in CHG. The mean percentage of practice of disinfectants was 72.5%. There was positive correlation among awareness and practice of main disinfectants. The awareness and nurses' salary explained 34.6% of variance in practice of disinfectants. Conclusion: An educational program focusing on strategy to enhance hospital nurses' awareness would be effective in improving their practice of disinfectants.