• Journal of Oriental Neuropsychiatry
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• v.22 no.3
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• pp.87-100
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• 2011

Objectives : Neurosis, psychosomatic disease from which most of out-patients suffer originated marital problem in clinical setting, In Oriental medicine, concept and clinical cases of the couple therapy is insufficient. So we suggest the theoretical background and evidence of oriental medical approach. Methods : We searched the theoretical perspectives of recent couple therapy and suggested the psychotherapy with couples in oriental medicine and its clinical utilization. Results : 1. Advantages of the couple therapy in oriental medicine were easy to relationship and emotional communication. because oriental medicine were available to approach of symptom pattern about somatic symptom due to marital problem. 2. Oriental medical therapy, for example, acupuncture, moxibustion, cupping, herbal medicine, etc. connects doctors and the patients easily, unlike dialogue-centered western psychotherapy. 3. The Ii-Gyeung-Byun-Qi Therapy(移精變氣療法) resolve the marital suppressed feeling easily, Gi-Un-Go-Roen Therapy (至言高論療法) is useful in four principle-marital role, communication, sex life, theory of Hwa-Byung. 4. The principle of 'sorrow restraints anger(悲勝怒)' and 'pleasure restraints sorrow(喜勝悲)' in Oh-Ji-Sang-Seung Therapy(五志相勝療法) accords with forgiveness and recovery that is ultimate goal of the couple therapy. Conclusions : Except existing therapy for recovery of marital relation, We suggest the somatic symptom centered approach based on mind and body unification in oriental medicine. This principle would bring the benefit from the marital to familial relation. From now on, we should correct the theory, need the theorical systematization. Then we should develop the program for recovery of marital relation and examine the hypothesis.

• Parasites, Hosts and Diseases
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• v.38 no.3
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• pp.151-158
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• 2000

Pneumocystis carinii is a major opportunistic pathogen which has been found in the lungs of a wide variety of mammalian host species, and the fact suggests the possibility of intraspecific variation. Until now, P. carinii from different mammalian species are differentiated as subspecies, and the rats are known to be infected by two subspecies. The present study investigated genetic heterogeneity of P. carinii isolates from two strains of rats in Korea and China by molecular karyotyping, RFLP and sequencing analysis. Karyotypes of P. carinii were grouped into three, two from two strains of rats In Korea and one from rats in China. However RFLP of PCR product of ribosomal and MSG gene of the P. carinii isolates showed same pattern. The sequence homology rates of ${\alpha}-tubulin$ DNA of the P. carinii isolates were 96% in Seoul Wistar rats, 93% in Seoul Sprague-Dawley rats, and 85% in Chinese Sprague-Dawley rats. The present finding confirmed that P. carinii from rats in Korea are grouped into two karyotype strains which are different from that of P. carinii from rats in China. The Chinese isolate shows a little different sequences of ${\alpha}-tubulin$ DNA.

• Journal of the Korean Society of Physical Medicine
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• v.10 no.2
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• pp.55-61
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• 2015

PURPOSE: The purpose of this study was to investigate recruiting order and onset time around shoulder muscle during the push-up according to the body tilting angle. METHODS: Twenty healthy young adult subjects were recruited for this study. They had no neurological and musculoskeletal disease. We used the sEMG for recording onset time of shoulder muscles. Shoulder Muscles were anterior deltoid(AD), posterior deltoid(PD), pectoralis major(PM), upper trapezius(UT). Body tilting angle were measured at 0 degree, 30 degree and 60 degree by using tilting table. Muscles contraction onset time were set by the push-up performed 3 times respectively. Mean of 3 measurements were used. And initiate onset time was decided by the Mean ${\pm}2$ SD in the threshold, more than 25ms. RESULTS: There were significant difference at 0 degree, 30 degree and 60 degree(p<.05). Muscles onset time were same order at 0 degree, 30 degree. UT occurred first of all contraction at 0 degree and 30 degree. And then contracted AD, PD, PM. But, at 60 degree, AD was the first contraction, and PM, UT, PD. CONCLUSION: Muscle recruitment order and onset time according to the body tilting was shown the difference when you do push-up. Therefore, this result, shoulder muscle recruitment pattern of according to the body tilting is different and it has to make effective shoulder exercise program.

• Women's Health Nursing
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• v.6 no.1
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• pp.82-95
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• 2000

The purpose of this study is to provide a basis to recognize the health behaviors of middle-aged women that are constructive to a healthy life style. Data were collected from interview of questionnaires completed by 208 middle-aged women living in Incheon from November 1 to 30, 1999. The questionnaires used in this study were obtained from publications on health-related topics shown in literature review. These topics included : health concept, diseases, use of tobacco, alcohol, caffeine, drug, exercise and diet, cause of stress and stress management. The data were analyzed by descriptive statistics using the SPSS program. The results of this study were as follows. 1. Middle-aged women though of concept of health as a doing daily living pattern(48.1%). 2. 49.5% of the middle-aged women had illness or disease, which included gastritis, arthritis, anemia, hypertension, indigestion and allergies. 3. 1.4% of the middle-aged women smoked cigarettes. Most of them began to smoke due to stress. 4. 42.3% of the middle-aged women drink alcohol. Most of them began drinking due to peer pressure. 5. 28.8% of the middle-aged women consumed caffeine-containing products 5-7 times per week. 6. 55.3% of the middle-aged women took drugs. Most of the drugs were digestant and analgesics. 7. 21.2% of the middle-aged women exercised more than 2 times per week. 8. Most of causes of stress were economic difficulties and sickness. The method of stress management were enduring and sleeping.

• Clinical Nutrition Research
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• v.6 no.3
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• pp.172-182
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• 2017

We investigated the association between dietary habits/food group consumption patterns and early risk of metabolic syndrome (MetS), a main cause for metabolic disease. Study participants were recruited from the health promotion center in Dong-A University Hospital and public advertisement. Study subjects (n = 243, 21-80 years) were categorized into three groups: Super-healthy (MetS risk factor [MetS RF] = 0, n = 111), MetS-risk carriers (MetS RF = 1-2, n = 96), and MetS (MetS $RF{\geq}3$, n = 27). Higher regularity in dietary habits (breakfast-everyday, regular eating time, non-frequent overeating, and non-frequent eating-out) was observed in the Super-healthy group than in the MetS-risk carriers, and particularly in the MetS subjects. The relationship between food group consumption patterns and MetS-risk related parameters were investigated with adjustment for confounding factors. Fruit consumption was positively associated with HDL-cholesterol, and tended to be negatively associated with waist circumference, triglyceride, LDL-cholesterol, and insulin resistance (IR). The consumption of low-fat meats and fish, and vegetables was negatively associated with hs-CRP. Specifically, the consumption of seafoods belonging to the low-fat fish was negatively associated with fasting glucose, hs-CRP, and interleukin (IL)-6. Anchovy/dried white baits consumption was negatively associated with fasting insulin and IR. Green-yellow vegetables consumption was negatively associated with fasting insulin, IR, and hs-CRP. On the other hand, sugars and fast-foods were positively associated with LDL-cholesterol. Additionally, fast-foods consumption was positively associated with hs-CRP and IL-6 levels. In conclusion, dietary habits/food group consumption patterns are closely associated with MetS-risk related parameters in Koreans. It may suggest useful information to educate people to properly select healthy foods for early prevention of MetS.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.38 no.4
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• pp.184-192
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• 2015

Korea has already entered into an aging society. In recent decades, the health problems for seniors has received considerable interest. We often see the elderly who have been struggled from discomfort or illness of the foot. Those foot related problems mainly cause from the use of improper shoes. Recently, shoe makers sell the shoes for seniors, so called comfort shoes, but the shoes are too expensive for seniors to buy easily. In this paper, we develop cheap insoles for seniors as an alternative of the comfort shoes and suggest the systematic process for the insoles development. This systematic process is as follows: 1) Survey the literature about the market of insole, 2) Investigate the standard size of body and foot for the seniors in Korea, 3) Analyze the customer needs by survey, 4) Study the walking pattern by experiments, and 5) Develop the novel insole for the seniors to relieve the inconveniences related with foot. From the newly developed insoles, the company B gains the sales increasing effect approximately 30% over through the increase in consumer satisfaction and company reputation and secures for intellectual property rights. Using the database from Korea Research Institute of Standards and Science, the reliability of developing technology of the functional insole has been obtained. The seniors are also enable to choose an alternative of comfort shoes for foot health. In the future, the insoles developed from this study have wide applications in the medical, cosmetic fields, and leisure sports fields. Accordingly, it seems to require more systematic studies utilizing Walk Analyzer and Foot Pressure Meter.

• BMB Reports
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• v.52 no.11
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• pp.665-670
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• 2019

Nucleotide-binding oligomerization domain protein 2 (NOD2), an intracellular pattern recognition receptor, plays important roles in inflammation and cell death. Previously, we have shown that NOD2 is expressed in vascular smooth muscle cells (VSMCs) and that NOD2 deficiency promotes VSMC proliferation, migration, and neointimal formation after vascular injury. However, its role in endoplasmic reticulum (ER) stress-induced cell death in VSMCs remains unclear. Thus, the objective of this study was to evaluate ER stress-induced viability of mouse primary VSMCs. NOD2 deficiency increased ER stress-induced cell death and expression levels of apoptosis mediators (cleaved caspase-3, Bax, and Bak) in VSMCs in the presence of tunicamycin (TM), an ER stress inducer. In contrast, ER stress-induced cell death and expression levels of apoptosis mediators (cleaved caspase-3, Bax, and Bak) were decreased in NOD2-overexpressed VSMCs. We found that the $IRE-1{\alpha}-XBP1$ pathway, one of unfolded protein response branches, was decreased in NOD2-deficient VSMCs and reversed in NOD2-overexpressed VSMCs in the presence of TM. Furthermore, NOD2 deficiency reduced the expression of XBP1 target genes such as GRP78, PDI-1, and Herpud1, thus improving cell survival. Taken together, these data suggest that the induction of ER stress through NOD2 expression can protect against TM-induced cell death in VSMCs. These results may contribute to a new paradigm in vascular homeostasis.

• Journal of Sasang Constitutional Medicine
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• v.33 no.3
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• pp.138-145
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• 2021

Objectives Edema occurs in various disorders, such as heart failure, nephrotic syndrome, renal failure, liver cirrhosis, and cancer. The excessive accumulation of interstitial fluid in limb tissue will often manifest with ankle and knee swelling and lowers patient's quality of life. But the conventional treatment includes restricting dietary sodium and using diuretics. The purpose of this study is about significant improvement of a patient with edema who had suffered from dependent gait accompanied by mild pain, after treatment by herbal medicine based on SCM(Sasang constitutional medicine). Methods The pattern identification of the patient was diagnosed with a superficial disease of Taeeumin. So after the admission, Gunyuljejo-tang was used, almost two times per day during 2 weeks. Also, we applied acupuncture routinely every day and western medicine as needed. We measured the circumferences of Lt. thigh and followed up the bioelectrical impedance analysis and checked the appearance of lower limb. Results and Conclusions The therapy was effective, and the circumferences, which was 59.69cm at onset time, decreased to 52.07cm almost same to the healthy side of her thigh. There was no more edematous sign on the body, either. This case showed that management of Taeeumin's healthy energy(呼散之氣, the energy of exhalation) could be effective in treating edema.

• Journal of the Korea Convergence Society
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• v.10 no.8
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• pp.21-26
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• 2019

This paper proposes a fatigue recognition method using the C4.5 algorithm. Based on domestic and international studies on fatigue evaluation, we have completed the fatigue self - assessment scale in combination with lifestyle and cultural characteristics of Chinese people. The scales used in the text were applied to 58 sub items and were used to assess the type and extent of fatigue. These items fall into four categories that measure physical fatigue, mental fatigue, personal habits, and fatigue outcomes. The purpose of this study is to analyze the leading causes of fatigue formation and to recognize the degree of fatigue, thereby increasing the personal interest in fatigue and reducing the risk of cerebrovascular disease due to excessive fatigue. The recognition rate of the fatigue recognition system using the C4.5 algorithm was 85% on average, confirming the usefulness of this proposal.

• Integrative Medicine Research
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• v.7 no.1
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• pp.95-102
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• 2018

Background: Hypertension is a major cause of cardiovascular disease and associated mortality, and postmenopausal women are at a high risk of hypertension. We aim to investigate the hypotensive effect and safety of acupuncture, focusing on postmenopausal women with prehypertension and stage 1 hypertension. In addition, we aim to investigate whether the effect of acupuncture treatment differed, depending on Sasang Constitution and cold-heat pattern. Methods: This study is designed as an intervention cohort study. Two hundred postmenopausal women aged <65 years with prehypertension or stage 1 hypertension living in Daejeon city in Korea will be recruited, and randomly assigned to either an acupuncture or no-treatment control group. The intervention will consist of four sessions; one session will include acupuncture performed 10 times for 4 weeks. There will be a 20-week observation period after each session, and the total study duration will be 96 weeks. Acupuncture will be applied at the bilateral Fengchi (GB20), Quchi (LI11), Zusanli (ST36), and Sameumgyo (SP6) acupoints. The effect of acupuncture will be evaluated by comparing the change in systolic and diastolic blood pressure between the acupuncture and control groups every 4 weeks until the end of the study. Discussion: To evaluate the success of blood pressure management, long-term observation is required, but no long-term studies have been conducted to evaluate the effect of acupuncture on blood pressure in postmenopausal women. To our knowledge, this study will be the first long-term study to investigate this issue for more than 6-8 weeks.