• 한국의사학회지
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• 제20권1호
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• pp.83-87
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• 2007

Since the beginning of mankind humans labored to survive, and during this process damages and illnesses developed and jeopardized their lives. Through this, the people came to know that touching seats of disease and wounds reduces or relieves the pain. Based on this, the people started to understand the technical process of stimulating the body with the hands and began to systemize it to use it for medical purposes. Chuna medicine was completed that way and this study is one that organizes information related to its history.

• 한국의사학회지
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• 제17권2호
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• pp.45-62
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• 2004

In this paper, we will take a look at the perception of gynecological diseases in the JinYuanSiDaJia (金元四大家-the four great schools of Jin Yuan), including the academic schools LiuWanSu(劉完素), ZhangCongZheng(張從正), LiGao, and ZhuZhenheng(朱震亨) during JinYuan Dynasty(金元時代). We also examined the medical history of gynecology up until the MingQingDynasty(明淸時代) when the dialectical system on gynecological diseases was relatively complete.

• 한국의사학회지
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• 제20권2호
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• pp.111-115
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• 2007

Since the beginning of mankind humans labored to survive, and during this process damages and illnesses developed and jeopardized their lives. Through this, the people came to know that touching seats of disease and wounds reduces or relieves the pain. Based on this, the people started to understand the technical process of stimulating the body with the hands and began to systemize it to use it for medical purposes. Chuna medicine was completed that way and this study is one that organizes information related to its history.

• Journal of Yeungnam Medical Science
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• 제39권4호
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• pp.269-277
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• 2022

The amyloid hypothesis has been considered a major explanation of the pathogenesis of Alzheimer disease. However, failure of phase III clinical trials with anti-amyloid-beta monoclonal antibodies reveals the need for other therapeutic approaches to treat Alzheimer disease. Compared to its relatively short history, optogenetics has developed considerably. The expression of microbial opsins in cells using genetic engineering allows specific control of cell signals or molecules. The application of optogenetics to Alzheimer disease research or clinical approaches is increasing. When applied with gamma entrainment, optogenetic neuromodulation can improve Alzheimer disease symptoms. Although safety problems exist with optogenetics such as the use of viral vectors, this technique has great potential for use in Alzheimer disease. In this paper, we review the historical applications of optogenetic neuromodulation with gamma entrainment to investigate the mechanisms involved in Alzheimer disease and potential therapeutic strategies.

• 대한임상독성학회지
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• 제15권1호
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• pp.24-30
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• 2017

Purpose: This study was conducted to investigate the frequency and clinical characteristics of anaphylaxis patients who are registered inaccurately with other disease codes. Methods: Study subjects presenting at the emergency department (ED) were retrospectively collected using disease codes to search for anaphylaxis patients in a previous studies. The study group was divided into an accurate and inaccurate group according to whether disease codes were accurately registered as anaphylaxis codes. Results: Among 266 anaphylaxis patients, 144 patients (54%) received inaccurate codes. Cancer was the most common comorbidity, and the radio-contrast media was the most common cause of anaphylaxis in the accurate group. Cutaneous and respiratory symptoms manifested more frequently in the inaccurate group, while cardiovascular and neurological symptoms were more frequent in the accurate group. Blood pressure was lower, and shock and non-alert consciousness were more common in the accurate group. Administration of intravenous fluid and epinephrine use were more frequent in the accurate group. Anaphylaxis patients with a history of cancer, shock, and epinephrine use were more likely to be registered as anaphylaxis codes accurately, but patients with respiratory symptoms were more likely to be registered with other disease codes. Conclusion: In cases of anaphylaxis, the frequency of inaccurately registered disease codes was higher than that of accurately registered codes. Anaphylaxis patients who were not treated with epinephrine at the ED who did not have a history of cancer, but had respiratory symptoms were at increased risk of being registered with disease codes other than anaphylaxis codes.

• 대한정형도수물리치료학회지
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• 제18권2호
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• pp.9-21
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• 2012

Background: The purpose of this study was to analysis and to give information about the type of orthopedic manual physical therapy research by KAOMPT Journal from 1995 (Volume 1) to 2011 (Volume 17). The number of research paper were total 212 studies. Method: The studies were analysed with retrospective descriptive study. The results of data analysis was as follow; Results & Conclusion: 1. The studies was analysed 6 study field; manual therapy for disease field (130 studies), the therapeutic (16 studies), the effects of manual therapy education method, learning model (7 studies), medical insurance, history, politics of manual therapy (3 studies), and others (19 studies). 2. In the manual therapy of disease field, there were 4 groups of disease; bone disease (43 studies), soft tissue and muscles disease (57 studies), nerve disease(24 studies), and the others (6 studies). The main disease were low back pain, stroke, HIVD. 3. In the assessment, and intervention field, there were only 5 studies during from 1995 to 2000, but the studies from 2001 to 2011 were more increased 21 studies. 4. In the effects of manual therapy education method, learning model, there were very few studies (7 studies), so it will be needed more studies in this field. 5. In the other fields such as more political issue, history, medical insurance for the manual therapy there were few studies, so it will be needed more advanced studies in this field.

• Tuberculosis and Respiratory Diseases
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• 제73권1호
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• pp.48-55
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• 2012

Background: The epidemiology of tuberculosis (TB) has been assessed based on the data of the analysis of TB patients notified to the surveillance system in Korea. However, the national status of TB is not validated through this surveillance system. The objective is to determine the epidemiology of TB and to understand the accurate status of TB patients treated in private institutions. Methods: Medical records of 53,579 patients who had been diagnosed with TB in 2008 were analyzed. Results: Among 53,579 patients, the number of sputum smear positive cases was 15,639(29.2%) and the number of new cases was 39,191 (73.1%). The drug resistance rate of new cases was 5.3%, while the rate stood at 13.3% for TB patients with treatment history. The number of multi-drug resistant TB (MDR-TB) patients was 2,472 (4.6%), which consists of 2.9% of new cases and 9.3% of TB patients with prior treatment history. The number of extensively drug-resistant TB patients was 749 (1.4%), consisting of 1.1% of new cases and 2.2% of TB patients with prior treatment history. In terms of treatment outcomes, 66.4% of all TB patients, 70.5% of new cases, 64.4% of relapse cases, and 46.8% of MDR-TB cases were cured or completed. It was inferred that in 2008, the total number of TB patients reached 70,767, 145.6 per 100,000 people (95% confidence interval, 145.5~145.7). Conclusion: We conclude that the medical records review of the Health Insurance Review and Assessment Service (HIRA) data can be very effective in promoting the understanding of the current status of TB in private institutions.

• 한국의사학회지
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• 제27권2호
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• pp.1-9
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• 2014

Objectives : Most academic societies have their own journals. Those journals represent the trends of academic societies' studies. Therefore, it is important to review articles in journals. Korean Society of Medical History (KSMH) has Journal of Korean Society of Medical History (J. of KSMH). We analyze articles in J. of KSMH and try to recognize the trends. Methods : From Vol. 12 No. 2 in 1999 to Vol. 27 No. 1 in 2014 of the J. of KSMH, we retrieved article's headings and analyzed those subjects. Results : We got 342 research articles about ; book 97, person 44, theory 65 (medical theory 48, thought 8, origin of word and story 9), clinical research 42 (disease 19, method 16, treatment 7), system of medicine and medical treatment 22 (system of medicine 10, system of medical treatment 12), mutual and comparative study in medicine 18 (mutual study 14, comparative study 4), etc. 56 (materia medica and prescription 23, trends study and essay 18, traditional medicine informatics 10, community medicine 5). Conclusions : J. of KSMH contained several subjects based on medical history ; book, person, theory, thought, origin of word and story, clinical research, mutual and comparative study in medicine, etc. However, the subjects were biased to books and persons.

• 대한한의학원전학회지
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• 제22권1호
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• pp.111-120
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• 2009

"Sibeongron(時病論)" is a book that was written by Noepung(雷豐, Leifeng) in the latter period of Cheong(淸) dynasty. In this book, Noepung described the Siryeong(時令) disease by oegam(外感), and the theoretical tool he used to analyze the Siryeong disease was the Ungi(運氣) theory based on "Naegyeong(內經)". Based on the Ungi theory, Noepung(雷豐) classified the Siryeong(時令) disease into two groups of singam(新感) and bokgi(伏氣), so that his theory of Siryeong disease could successfully describe the Siryeong diseases of four seasons. To understand his theory of Siryeong disease, it is very important to understand the concept of the relation between the division of time and the etiological cause by oegam(外感). Based on this concept, this study will be analyzing how each Siryeong disease was defined in his etilogical view which had been originated from the Ungi(運氣) theory in "Naegyeong".

• Clinical and Experimental Pediatrics
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• 제57권6호
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• pp.287-291
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• 2014

Moyamoya disease is a cerebrovascular condition that results in the narrowing of the vessels of the circle of Willis and collateral vessel formation at the base of the brain. Although relationships between Graves' disease and cerebrovascular accidents in Moyamoya disease are obscure, the coexistence of the two diseases is noteworthy. Moyamoya disease has been rarely reported in adolescent patients with thyrotoxicosis. Recently, we encountered two adolescent Korean patients with Moyamoya disease associated with Graves' disease who presented with episodic right-sided hemiparesis and syncope. These two girls who had Graves' disease had no history of other diseases or head trauma. A thyroid function test revealed a euthyroid state and a high thyroid-stimulating hormone (TSH) receptor antibody titer at that time. The patients were diagnosed with Moyamoya disease based on brain magnetic resonance angiography and cerebral four-vessel angiography. The patients underwent cranial revascularization by encephalo-duroarterio-synangiosis as soon as a diagnosis was made, which resulted in successful symptom resolution. They fared well and had no additional neurological symptoms as of their last follow-up visits. Here, we report these two cases of confirmed Moyamoya disease complicated by Graves' disease with a review of the literature, and discuss the possible association between the two diseases. To our knowledge, this is the first report in South Korea on Moyamoya disease associated with Graves' disease in adolescents with a euthyroid.