• Title/Summary/Keyword: disease history

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Diabetes, Overweight and Risk of Postmenopausal Breast Cancer: A Case-Control Study in Uruguay

  • Ronco, Alvaro L.;Stefani, Eduardo De;Deneo-Pellegrini, Hugo;Quarneti, Aldo
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.1
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    • pp.139-146
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    • 2012
  • Obese postmenopausal women increase their risk of developing breast cancer (BC), in particular if they display an android-type pattern of adiposity, which is also associated to increased risks of diabetes mellitus, hypertension and cardiovascular disease. In order to explore the associations among anthropometry (body mass index, body composition, somatotype), some specific items of medical history (diabetes, hypertension, dislypidemias, hyperuricemia) and the risk of BC in Uruguayan women, a case-control study was carried out between 2004-2009 at our Oncology Unit. 912 women of ages between 23-69 years (367 new BC cases and 545 non hospitalized, age-matched controls with a normal mammography) were interviewed. Twenty body measurements were taken in order to calculate body composition and somatotype. Patients were queried on socio-demographics, reproductive history, family history of cancer, a brief food frequency questionnaire and on personal history of diabetes, dislypidemias, hyperuricemia, hypertension and gallbladder stones. Uni- and multivariate analyses were done, generating odds ratios (ORs) as an expression of relative risks. A personal history of diabetes was positively associated to BC risk (OR=1.64, 95% CI 1.00-2.69), being higher among postmenopausal women (OR=1.92, 95% CI 1.04-3.52). The risks of BC for diabetes in postmenopausal women with overweight combined with dislypidemia (OR=9.33, 95% CI 2.10-41.5) and high fat/muscle ratio (OR=7.81, 95% CI 2.01-30.3) were significantly high. As a conclusion, a personal history of diabetes and overweight was strongly associated to BC. The studied sample had a subset of high-risk of BC featured by postmenopausal overweight and diabetic women, who also had a personal history of hypertension and/or dyslipidemia. The present results could contribute to define new high risk groups and individuals for primary as well as for secondary prevention, since this pattern linked to the metabolic syndrome is usually not considered for BC prevention.

Composition and Contents of the Monograph on Theory of Cold Damage - "Sanghankyeongheombangyochal"(傷寒經驗方要撮) in the Late Joseon Dynasty (조선후기(朝鮮後期) 상한(傷寒) 연구(硏究)의 일면(一面) - 조선후기(朝鮮後期) 상한(傷寒) 연구서(硏究書) "상한경험방요촬(傷寒經驗方要撮)"의 구성과 내용 -)

  • Oh, Jun-Ho;Park, Sang-Young;Kim, Hyun-Koo;Kwon, Oh-Min
    • Korean Journal of Oriental Medicine
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    • v.18 no.1
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    • pp.25-34
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    • 2012
  • Objective : This study was carried out with focus on written by Joh, Taek-seung (曺澤承) and Joh, Byeong-who(曺秉矦) in the relation of father and son in 1933. This book is a medical book including rare data, which has never been reported to academic circles all this while. Method : First, this study looked into the authors of this book and its history of publication. Further, this study analyzed the composition and contents of this book. Lastly, this study summed up the meaning of this book from the standpoint of medical history. Result : The authors were Confucian doctors who were active in the latter era of the Joseon Dynasty and also in the period of Japanese colonial rule. They lived in Haenam district of Jeonlanam-do, and cured its neighboring local residents while studying. They published the book of by putting together their own medical experiences. The authors suggested their remedial prescription according to gender and age whereas Zhang Zhongjing(張仲景) suggested the remedial prescription according to Six-Meridian Pattern Identification & Syndrome Differentiation(六經辨證). In addition, the authors of gave weight to the relationship with internal damage. Additionally, the authors not only thought much of the relationship between internal damage and external damage but also thought of the weakness and strength of the healthy qi, and the new and the old of a disease as an important clue to medical treatment. It seems that such contents was influenced by (東醫寶鑑). Conclusion : shows the results of the research on which was spontaneously conducted in Joseon.

왕실의 의약(議藥)

  • Hong, Seyoung
    • The Journal of Korean Medical History
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    • v.23 no.1
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    • pp.105-113
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    • 2010
  • Seungjeongwon Ilgi["承政院日記"], the Diaries of Royal Secretariat of the Joeson Dynasty is the most massive compilation of records in Korean history. Medical records in Seungjeongwon Ilgi have been studied but the procedures of clinical discussion[議藥] have not yet been studied. In this paper, main agents of clinical discussion, formation of participant doctor system, particularity of clinical discussion in Royal Court and problems derived from it will be discussed. Main agents of clinical discussion were court doctors[內醫], royal doctors[御醫] and participant doctors[議藥同參]. The king himself decided ultimately as a matter of form. Head of the Medical Dpt. of the Palace[藥房都提調] was in charge of attending to king, but head of the court doctor[首醫] led the actual discussion of deciding treatment. The Medical Dpt. of the Palace[內醫院] was divided into three sectors-court doctor division, acupuncture doctor division and participant doctor division. Palace doctors payed a great attention to avoid serious error. This tendency led them occasionally to passive management. Sometimes aggressive treatment is needed in the course of treating disease, but palace doctors tended to choose slow and gradual methods. It induced minor conflict between palace doctors and participant doctors from outside palace, because doctors from outside palace subordinated effectiveness. Their opinion had not been always recognized by court doctors. However, their role was meaningful because they provided flexibility to the rigidity of clinical discussion in the palace. It is important to evaluate clinical records in Seungjeongwon Ilgi["承政院日記"]. If we have broader eye on the clinical procedure in the palace, we can estimate the value of the contents more objectively and accurately.

Self-controller of Saam Acupuncture Viewed from the Aspect of the Five Viscera Interaction (오장상섭(五臟相涉)의 측면에서 살펴본 사암침법(舍岩鍼法)의 억관(抑官)과 보관(補官))

  • Oh, Jun-Ho
    • Korean Journal of Acupuncture
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    • v.28 no.3
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    • pp.127-140
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    • 2011
  • Objectives : The aim of this study is to regulate the medical meaning about Kwan [self-denial] which is used by Jeongkyeok [reinforcing the weak body part] and Seungkyeok [consolidating the weak body part while inducing cathartic action of comparatively stronger body part] of Saam Acupuncture in common. Methods : This study generalized the method of understanding 'The Five Viscera Interaction' in Oriental Medicine from the perspective of literature and considering human organs in the medical context. Results and Conclusions : 1. There existed 'The Five Viscera Interaction' theory regulating the correlation between the five viscera headed by "Nankyeong" in the traditional Oriental medicine. The five viscera interaction theory was used as the standard of judging the symptom and the prognosis of a disease in the history of Oriental medicine and further used even as the method of preventing and treating diseases. 2. The treatment included in "Biyebaekyobang", a medical book in the period of Goryeo, can be rated as the most developmental form of medical theory which applied 'the five viscera interaction theory' to clinical treatment. The author of "Biyebaekyobang" managed to break away from the schematism of the five viscera interaction through the method of treating two internal organs using one organ treatment and applying the individually different relations between organs. "Biyebaekyobang" shows close similarities to Saam Acupuncture. 3. The organs handled in Saam Acupuncture has a significance in that it put forward the part which had not been aggressively dealt with in medical history up until then.

Analysis of Pediatric Prescription in 『Juchonsinbang』 and Intergenerational Relationships of Medical Knowledge (『주촌신방(舟村新方)』 소아질환의 처방 분석과 의학지식의 전승 관계 고찰)

  • Hwang, Jihye;Han, Jiwon;Kim, Namil
    • The Journal of Korean Medical History
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    • v.31 no.1
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    • pp.43-55
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    • 2018
  • This is a review of Juchon (舟村) Sinman's (申曼) book "Juchonsinbang (舟村新方)", describing generations of clinical experience in pediatric practice. Written during King Sukjong era in the middle of the Joseon Dynasty, JuchonSinman used symptoms and general disease terminology, including prescription and treatments employed over generations, so the public could easily utilize the information. "Juchonsinbang (舟村新方)" "pediatric (小兒編)" is characterized by a symptom differentiation method of prescribing herbs which allowed the reader to add or subtract various substances according to symptoms based on Tongchibang (通治方). "Juchonsinbang" includes unique prescriptions and new ways to distinguish acute infantile convulsion (急驚風) according to the cause of fright. Although these prescriptions were not completely new, they present an aspect of an empirical book including JuchonSinman's clinical experience based on existing medical theories. "Juchonsinbang" has a medico-historical value in that it was cited in many medical books such a "Danbangsinpyun (單方新編)", "Sujinggyunghumsinbang (袖珍經驗神方)", and "Hanbang medical pediatric book (漢方醫學小兒全科)" in 1910-30.

Study of Clinical Discussion Records Lee Gong-yoon Involved (이공윤의 의약동참기록 연구)

  • Kim, Dong-Ryul;Cha, Wung-Seok
    • The Journal of Korean Medical History
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    • v.29 no.2
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    • pp.61-69
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    • 2016
  • This study was performed to examine the clinical discussion records where Lee Gong-yoon, participated in Royal treatment at Joseon Dynasty, was involved. Lee Gong-yoon who scouted from the outside had participated in the medical center of the Royal Family for several years as a royal doctor. But he preferred aggressive prescriptions and behaved indiscreet. Eventually, he was exiled when Kyung-Jong who was the 20th king of the Joseon Dynasty died. He was harshly criticized until the year crown prince ascended the throne following Kyung-Jong. But some officials started to defend him since March of the next year. They recognized Lee Gong-yoon's aggressive prescriptions and indiscreet behavior. But mentioned that some very aggressive prescriptions didn't come from his own idea. After they proved their insistence true, his place of exile was changed from island to outland. Different from other doctors who focused on patients' 元气 ($yu{\acute{a}}nq{\grave{i}}$), Lee Gong-yoon focused on removing patients' symptoms when he decided to cure a disease. And also he had considerable insight of "醫學入門 ($y{\bar{i}}xu{\acute{e}}r{\grave{u}}m{\acute{e}}n$)". Despite of his high degree of medical knowledge, unconventional character and behavior made the end of his life unfortunate.

Experience in Jang Jong-jeong's Vomiting Treatment (장종정(張從正) 토법(吐法)의 경험례)

  • Kim, Eui tae;Cha, Ung-Seok;Kim, Nam il
    • The Journal of Korean Medical History
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    • v.19 no.2
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    • pp.87-100
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    • 2006
  • Jang Jong-jeong thought that, because all diseases come from miasma, for treating diseases, it is important to attack or remove miasma infiltrating into the body. Thus, he treated diseases using three methods, namely, vomiting against miasma on the top, sweating against miasma on the surface, and diarrhea against miasma on the bottom. Among them, vomiting is rarely used in contemporary Oriental medicine, but still one of major disease treatment methods. Vomiting is quite meaningful in today's clinics and particularly effective for acute diseases, the miasma of which is in the upper chest. According to the present researcher's experiences, it is effective in cases that the pathological symptoms are observed in the upper chest such as early stroke, dyspepsia, chest congestion and congestion heat. For vomiting, the researcher applied Dokseongsan, Samseongsan, Gwachesan, Gangyeomtang, Bangpungtongseongsan, etc. Dokseongsan was used for vomiting in a cool way, and Samseongsan and Gwachesan were used for vomiting in a warm way. Bangpungtongseongsan was used when inner heat was choked up by the attack of external miasma and when the pathological symptoms of Bangpungtongseongsan were observed.

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The Transition of Theory on the Outbreak and Transmission of Wasting-Thirst (소갈병(消渴病) 기전(機轉)에 관한 이론의 변천)

  • Cho, Sun Young;Yoo, Won Joon;Gang, YeonSeok
    • The Journal of Korean Medical History
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    • v.21 no.2
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    • pp.95-113
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    • 2008
  • Unsatisfied with the modern medicine's treatment of diabetes, patients diagnosed with the disease turn to alternative medicine for treatment. A look at the percentage of people using alternative medicine marked 72.8% in the United States and more than 60% in Korea in 2006. The most preferred form of alternative medicine turned out to be usage of dietary supplements and herbal medicine. Most of the dietary supplements and herbs that diabetic patients use largely originated from their usage in East Asian Traditional Medicine. As Western Medicine made its way into East Asia in late 18th century, excessive efforts were made to translate Western medical terminology into traditional medical terminology equivalents. In the process of doing so, wasting-thirst became a concept equivalent to diabetes. Theories regarding the pathogenic outbreak and transmission of wasting-thirst has been supplemented and progressed according to needs and even showed new tendencies. Profound understanding of wasting-thirst achieved through historical research is expected to lead to proper application of wasting-thirst treatment methods in treating modern diabetes.

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Study on Extraction of Headwords for Compilation of 「Donguibogam Dictionary」 - Based on Corpus-based Analysis - (『동의보감사전』 편찬을 위한 표제어 추출에 관한 연구 - 코퍼스 분석방법을 바탕으로 -)

  • Jung, Ji-Hun;Kim, Do-Hoon;Kim, Dong-Ryul
    • The Journal of Korean Medical History
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    • v.29 no.1
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    • pp.47-54
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    • 2016
  • This article attempts to extract headwords for complication of "Donguibogam Dictionary" with Corpus-based Analysis. The computerized original text of Donguibogam is changed into a text file by a program 'EM Editor'. Chinese characters of high frequency of exposure among Chinese characters of Donguibogam are extracted by a Corpus-based analytical program 'AntConc'. Two-syllable, three-syllable, four-syllable, and five-syllable words including each Chinese characters of high frequency are extracted through n-cluster, one of functions of AntConc. Lastly, The output that is meaningful as a word is sorted. As a result, words that often appear in Donguibogam can be sorted in this article, and the names of books, medical herbs, disease symptoms, and prescriptions often appear especially. This way to extract headwords by this Corpus-based Analysis can suggest better headwords list for "Donguibogam Dictionary" in the future.