• 한국안광학회지
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• 제10권3호
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• pp.241-246
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• 2005

본 연구는 굴절이상을 가진 피검자의 단안에서 Netspeg lens를 착용 후 시력 개선의 상태를 P-VEP의 파형 분석을 통해서 검증하고자 하였다. P-VEP는 3 channel의 Bausch Lomb system으로 기록하였다. 10명의 성인 피검자(남성 5인, 여성 5명; 평균 21세, 연령은 19세와 23세 사이)의 눈을 검사하였다. 피검자는 전신건강, 약물복용, 유전, 알레르기 그리고 안질환을 포함하는 문진 등을 조사하였다. 시력과 굴절검사는 Netspeg lens를 사용하여 피검자의 단안을 기록하였다. 피검자는 P-VEP 기록을 하는 동안 교정된 시력을 통해서 단안의 P-VEP 자극을 본다. 연구의 결과 Netspeg lens를 사용한 단안은 사용하지 않는 눈에 비해서 시력 결상이 선영하게 자각되었다. 한편 P-VEP 검사에서는 Netspeg lens를 사용한 눈이 높은 진폭 나타 내었다. 그러나 P-VEP의 장복시간은 오히려 늦게 나타났다. 그러나 P-VEP이 형태에서는 Netspeg lens를 사용한 눈이 안정된 파형을 유지하였다. 한편 오른 눈과 왼눈의 유의성은 거의 없었다. 따라서 본 연구에서는 Netspeg lens를 사용한 단안에서는 그렇지 않는 눈에 비해서 시력과 시기능이 기능이 우수함을 나타내었다.

• Archives of Plastic Surgery
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• 제38권6호
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• pp.791-797
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• 2011

Purpose: Angiosarcoma is a rare and aggressive malignant soft tissue tumor. Due to a lack of the established optimal treatment modalities, however, an extensive resection followed by an early detection has been reported to be the best treatment of choice. We analyzed the clinical course of six patients, hence attempted to contribute to making a treatment plan for patients with angiosarcoma. Methods: Six patients who have been surgically treated between 2005 and 2010 are included. Through a retrospective analysis of the medical records, we evaluated the pattern of disease detection, a past history, time span between the detection and the primary surgery, surgical treatment modalities, time span between the primary surgery and the recurrence/metastasis, the sites of metastasis and the secondary treatment modalities. Results: The mean age of patients was 70.5 years; all male; and the sites were the scalp. Four patients underwent the reconstruction using a local flap with a skin graft and two patients using a free flap. The mean period elapsed until the primary operation since the identification was 7.3 months and until a recurrence or a metastasis occurred following the primary operation was 12 months. Four patients had pulmonary metastasis. As a secondary therapy, four patients underwent the radiotherapy and one was treated with the chemotherapy. At the present, five patients died and one undergoes a monitoring of the clinical course. Conclusion: It would be mandatory to shorten the length of hospital stay and to return patients to their daily lives as the earliest as possible using relatively simpler surgical methods, thus attempting to give them opportunity to resume their previous normal life.

• Archives of Plastic Surgery
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• 제36권3호
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• pp.351-355
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• 2009

Purpose: Cervical necrotizing fasciitis tends to involve the deep soft tissues and spread caudally to the anterior chest and mediastinum, often resulting in major complications and death. It may rapidly spread into the thorax along fascial planes, and the associated diagnostic delay results in this descending necrotizing mediastinitis. So, aggressive multidisciplinary therapy with surgical drainage is mandatory. We present a very rare case of descending necrotizing mediastinitis with literature review. Methods: A 53 years old male visited our department 7 days after trauma in neck. His premorbid conditions and risk factors of necrotizing fasciitis were concealed hepatoma, trauma history, chronic liver disease, and nutrition deficit. Computed tomographic scans of the head and neck region were performed in this patient : signs of necrotizing fasciitis, were seen in the platysma, sternocleidomastoid, trapezius muscle and strap muscles of the neck. Fluid accumulations involved multiple neck spaces and mediastinum. At the time, he diagnosed as necrotizing fasciitis on his neck and anterior chest. Necrotic wound was excised serially and we treated this with the Vacuum - assisted closure(VAC, Kinetics Concepts International, San Antonio, Texas) system device. After appropriately shaping the sponge and achieving additional 3 pieces drainage tubes in the pockets, continuous negative pressure of 125 mmHg was applied. The VAC therapy was utilized for a period of 12 days. Results: We obtained satisfactory results from wide excision, abscess drainage with the VAC system, and then split thickness skin graft. The postoperative course was uneventful. Conclusion: The refined technique using the VAC system can provide a means of simple and effective management for the descending necrotizing mediastinitis, with better cosmetic and functional results. Finally, the VAC system has been adopted as the standard treatment for deep cervical and mediastinal wound infections as a result of the excellent clinical outcome.

• Pediatric Infection and Vaccine
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• 제18권1호
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• pp.91-96
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• 2011

BCG는 M. bovis로부터 유래된 생백신으로 5-6세 미만의 소아 결핵 특히 결핵성 수막염이나 속립성 결핵과 같은 중증 결핵의 예방 효과가 인정되고 있다. BCG 접종 후 이상반응은 국소 궤양 형성, 국소 림프절염이 가장 흔하며, 드물지만 골수염, 파종성 감염과 같은 치명적인 합병증도 있다. 파종성 BCG 감염은 주로 면역저하 환자에게서 흔하게 관찰되며 면역 저하가 없는 소아에게서 발생한 파종성 BCG 감염은 국내 문헌상 보고가 없었다. 저자들은 13개월 여환이 BCG 접종 5개월 뒤 발생한 발열, 피부 결절 및 다발성 림프절 종대를 주소로 내원하여, 백 신 접종 부위 외에 2군데에서 M. bovis BCG를 확인한 후 파종성 BCG 감염으로 진단된 1례를 경험하였다. 환아는 isoniazid와 rifampin으로 치료받았으며 약 2주 간의 입원 치료 후 임상 증상이 호전되어 퇴원하였다. 3주뒤 외래 추적 관찰에서 역설적 반응으로 생각되는 림프 절 종대와 피부 결절이 진행하였으나 동일 약제를 유지하면서도 다시 임상 증상이 호전되었고 환아의 면역학적 검사상 이상 소견이 관찰되지 않았기에 이를 보고하는 바이다.

• Journal of Preventive Medicine and Public Health
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• 제39권3호
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• pp.229-234
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• 2006

Objectives: Cardiovascular disease is one of the main causes of death and morbidity in Korea. In this study, the prevalence and incidence of developing hypertension in a male-workers' cohort were investigated during 3-years follow-up with a view to find the risk factors that affected the development of hypertension. Methods: Among the 5,374 people who participated in a routine health check up, 3,852 people with normal blood pressure and who had no history of hypertension were prospectively followed up for 3 years. The classification of hypertension was based on the JNC7 report (the Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure). Life style factors and underlying diseases that were related to the risk factors of hypertension were collected by using a self-report questionnaires via the internet. Results: The prevalence of hypertension was 28.3% (1,520/5,374) at the first screening (2001). It was found that the incidence in 2004 of hypertension for the follow-up subjects (3,711) who had normal blood pressure in 2001 was 7.6 per 100 person-year. Multiple logistic regression analysis of the variables related to the risk factors of hypertension was carried out. The relative risks were 1.037 (95% CI=1.022-1.053) as the age increased 1 year and 1.039 (95% CI=1.023-1.055) as the body mass index increased $1kg/m^2$. The relative risk for the prehypertensive group was 2.501 (95% CI=1.986-3.149) compared to the normotensive group. These results showed that age, body mass index and the baseline blood pressure were significantly related to the incidence of hypertension. Conclusions: The incidence of hypertension was 7.6 per 100 person-year during follow-up. It was concluded that the risk factors for developing hypertension in the short-term were age, BMI, and prehypertension; Especially, this showed that it is necessary for prehypertensives to manage their body weight and blood pressure to prevent hypertension in middle-age by modifying their life style.

• 대한지역사회영양학회지
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• 제2권3호
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• pp.338-348
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• 1997

This study was conducted to investigate the health and nutritional status of 123 middle aged men at their worksite in Taejon. The results of this study on the factors that influence their health and nutritional status were as follows : 1) 74.8$\%$ of the subjects had history in the order of alimentary, heat, liver, diabetic and pulmonary diseases. 30.3$\%$ stopped smoking at 42.3% yrs. and 74.5$\%$ smoked more than 10 cigarets per day. Also 71.9$\%$ drank 2-3 times per week and 35.3$\%$ drank 1-2 times per week. 91.4$\%$ exercised more than 30min every day. 2) 54.4% showed concerns about their health whereas 20.3$\%$ were afraid that they night get sick. 3) 90.4$\%$ ate regularly and 54.5$\%$ worried about their cholesterol, salt, fat and MSG intakes. 48.7$\%$ ate out 1-2times per week and their favorite foods eaten outside were Korea. 4) 41.5$\%$ were classified as 'normal A', 30.9$\%$ 'normal B' group and high blood pressure and liber diseases in 'doubtful for disease' group were pointed out from their 1996 health check ups. 5) By Broca index, 39.8$\%$ were overweight and 9.8% were obese however by BMI only 23.6% were overweight. According to the relationship between calculated and self recognized obesity, 62.4$\%$ categorized themselves into the right weight range but 34.3$\%$ thought they were thinner than they were. 6) 43.9$\%$ were border line in cholesterol intake and 12.1$\%$ needed medical care for high blood cholesterol. 7) The Average energy intake was 1970.6㎉(80.9$\%$ RDA) with a 65 :19 : 16 ratio of carbohydrate : protein : fat. Protein, Fe, thiamin, riboflavin, niacin and Vit. A. 8) Occupation, regularity of meals, partner's job, income. smoking, alcohol drinking, health concerns and eating out were the factors that influenced the subject's nutrient intakes and health status. from this study, it was found that middle aged men needs to know their health and nutritional status and to be educated correct health and nutritional information through formal or informal channel. The worksite is the vest place to do this and we want these results to be used to develop the nutrition education program for middle aged men at the worksite.

• 대한정형외과스포츠의학회지
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• 제9권2호
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• pp.85-90
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• 2010

목적: 재발성 슬개골 탈구에서 경피적 외측부 유리술 및 관절경적 내측부 중첩술의 결과에 대해 알아보고자 한다. 대상 및 방법: 2001년 3월부터 2008년 3월까지 외상 후 발생한 재발성 슬개골 탈구로 수술적 치료를 받은 환자 중 2년 이상 추시 관찰한 31례를 대상으로 하였으며 평균 연령은 24.2세, 평균 추시 기간은 47.4개월이었다. 결과: 술 전 일치각은 평균 24.8도, 외측 슬개-대퇴골각은 평균 -6.2도, Lysholm score는 평균 75점이었다. 술 후 일치각은 평균 -2.8도, 외측 슬개-대퇴골각은 10.2도로 정상범위를 회복하였으며 Lysholm score도 95점으로 향상 되었다. 재발성 탈구는 총 5례에서 발생하였으며 이 중 3례에서 대퇴골 이형성증이 관찰되었다. 결론: 경피적 외측부 유리술 및 내측부 중첩술은 합병증이 드물고 임상적으로 만족할 만한 결과를 보여 재발성 슬개골 탈구에 대한 치료에 유용한 방법으로 사료된다. 그러나 대퇴골 활차의 선천성 변형이 있다면 다른 수술적 치료를 고려해야 할 것이다.

• 대한한방소아과학회지
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• 제24권2호
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• pp.112-125
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• 2010

Objectives The purpose of this study is to find the relationships between the allergy and weakness in children in Seong-Dong district. Methods 802 day care centers children were participated for survey on allergic disease, risk factors, and weakness. From the result, we analyzed the relationships between the aforementioned factors. Results 1. 802 children were participated for the survey. We eliminated survey answers with unclear answers, and selected 792 survey sheets as our final subject of study. The age of majority of subjects(720 children) were between one to six years old, and the others were under the age of one and over seven. 2. The prevalence rate of asthma in a lifetime was 6.69%, allergic rhinitis was 14.87%, atopic dermatitis was 28.82%, allergic conjunctivitis was 6.29%, food allergies was 9.58%, and drug allergies was 1.4%. In 2009, the prevalence rate of allergies during treatments is 6.69% for asthma, 13.41% for allergic rhinitis, 13.64% for atopic dermatitis, 4.13% for allergic conjunctivitis, 5.23% for food allergies, 0.96% for drug allergies. 3. The significant risk factors were types of dwelling, pet with fur, dirty environments without vacuum cleaners, the numbers of times bed covers were washed, frequency of air ventilation, changes in body after moving, family history. 4. The distribution of the number of children with weakness within the five visceras were respiratory weakness, digestive weakness, psychoneurologic weakness, neuromotor weakness, and urogenital weakness in the order of most to the least. More specifically, children who only has respiratory weakness were the majority, while children who have respiratory and digestive weaknesses, children who have respiratory, digestive, and psychoneurologic weaknesses, children who have respiratory and psychoneurologic were followed. 5. With the exception of children with urogenital weakness, Most of the children with respiratory weakness, digestive weakness, psychoneurologic weakness, and neuromotor weakness had been treated for allergies in 2009, while children who were diagnosed with allergic diseases at least once in their lifetime most likely had weak respiratory, digestive or psychoneurologic systems. Conclusions The results of this study showed that there was a correlation between children with weak viscera and children with allergic diseases. However, further research would be necessary.

• 정신신체의학
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• 제21권1호
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• pp.27-43
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• 2013

연구 목적 일반 인구에서 스트레스, 우울 정도, 신체질환 간의 관계와 우울증의 위험 요인을 확인하고자 연구를 진행하였다. 방 법 2009년 1월부터 2009년 12월까지 고려대학교 구로병원 건강검진센터에 내원한 일반인 1,764명에서 인구역학 자료를 조사하고 PSS와 PHQ-9 설문지를 시행하였다. 스트레스군, 우울군, 신체질환군을 구분하여 스트레스, 우울, 신체질환 간의 상관분석과 로지스틱 회귀분석을 시행하였다. 결 과 1,476명의 연구 대상자 중 198명(11.8%)이 우울군에 해당되었으며, 평균 PSS 점수(23.19점)와 평균 PHQ-9 점수(12.95점) 모두 정상군에 비해 높았다. 스트레스가 높을수록, 신체질환이 많을수록 우울 점수도 증가하였다. 여성, 최근의 건강이상으로 내원한 사람, 불규칙적인 운동과 흡연력, 협심증과 뇌경색 기왕력이 있는 군에서는 우울증의 위험도가 증가하였다. 결 론 본 연구에서 PSS, PHQ-9은 건강검진센터에서 정신건강 선별검사를 시행할 수 있는 유용한 기회를 제공하였다. 스트레스를 많이 받고 신체질환이 많을수록 우울증의 위험도가 증가하므로, 신체질환이 동반되었거나 건강하지 못한 생활습관을 지닌 개인에서 정신질환 선별검사가 필요하겠다.

• 한국안광학회지
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• 제19권3호
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• pp.285-293
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• 2014

목적: 초등학생에서 일반인을 대상으로 가시홍채직경(수평, 수직) 및 검열의 폭과 길이를 측정하여 이들의 상관관계 및 소프트콘택트렌즈 크기의 연령별 적합성을 알아보고자 하였다. 방법: 안질환이 없고 외형적으로 미용을 포함한 눈 수술을 하지 않은 초등학생에서 일반인 총 514명(1028안)을 대상으로 가시홍채직경(수평, 수직)과 검열의 폭과 길이를 측정하고 분석하였다. 결과: 가시홍채수평직경과 수직직경은 연령별 남녀 간의 유의한 차이는 없었으나, 중학생과 대학생의 검열의 길이와 고등학생의 검열의 폭은 남학생과 여학생 간 유의한 차이가 있었다(p<0.05). 또한, 남녀 모두 가시홍채수평직경, 가시홍채수직직경, 검열의 길이 그리고 검열의 폭에서 연령별로 유의한 차이를 보였다. 가시홍채직경과 검열의 크기는 문헌에 기준한 정상범위 근사치보다 검열의 폭은 남녀를 포함한 전체 대상자의 27.9%, 가시홍채직경은 36.0%가 작은 것으로 나타났다. 결론: 가시홍채직경과 검열의 크기는 소프트콘택트렌즈의 직경 결정에 영향을 미치며, 특히 렌즈 삽입시 피검자의 불편함을 덜어주기 위해서 좀 더 세심하게 고려되어야 할 사항이라고 사료된다.