• Journal of Chest Surgery
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• 제29권9호
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• pp.1010-1016
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• 1996

중증근무력증환자에 있어서 흉선 절제술은 대상이 되는 환자의 선택 기준이나 수술시기, 수술 방법에 있어서 아직까지 논란이 되고 있지만 긍정적으로 적용될 수 있는 치료 방법이다. 연세대학교흉부외과 학교실 신촌 세브란스병원에서는 1983년 1월부터 1994년 12월까지 중증근무력증으로 흉선 절제술을 시행한 82명의 환자를 대상으로 연구하였다. 수술 사망은 1명에서 발생하였고 수술 후 추적은 75명에서 가능하였고 평균 추적기간은 56.9개월 이었다. 완전관해된 28명(37.3%)을 포함하여 64명(85.3%)에서 수술로 인한 효과를 볼 수 있었다. 동반된 질환으로는 갑상선 질환이 8예로 가장 많았는데 이중 7명(87. 5%)이 완전관해를 보여 갑상선 질환을 동반하지 않은 환자 67명중 21명(31.3%)의 완전관해보다 높은 치료 성공율을 나타내었다. 수술 전 병력 기간이 2년 미만인 환자 32명중 16명(50%), 2년 이상인 환자 43명중 12명(27.4%)이 완전관해를 보여 수술전병력 기간이 2년 미만인 경우 높은 치료율을 보였다. 결론적으로 중증근무력증환자에 있어서 흉선 절제술 후 완전관해율은 갑상선 질환의 동반 여부와 수술 전 병력기간에의해 영향을 받음을 알 수 \ulcorner었으며 병의 발생 연령(40세 이상),흉선종의 동반,고령 및 남자의 경우 수술 후 완전관해율을 떨어뜨리는 것으로 나타났지만 통계적 의의는 없었다. 흉선의 조 직학적 소견으로 정상과 흉선 비후사이에 있어서 완전관해율의 차이는 보이지 않았다. 일반적으로 흉선 절제술은 대부분의 중증근무력증환자에 있어서 효과가 있었으나 임상증상적 분류로 기 속한 환자군은 수술로 인한 효과가 없었다.

• 한방안이비인후피부과학회지
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• 제13권2호
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• pp.140-151
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• 2000

Acne is a common chronic disease which most frequently affects the face, appearing in both males and females near puberty, and in most cases becomes less active as adolescence ends. The intensity and duration of activity vary for each individual. The disease may be minor, with only a few comedones or papules, or it may occur as the highly inflammatory and diffusely scarring acne conglobation. Permanent scarring of the skin and psyche can result from such inaction. The disease, however, has implications far beyond the few marks that may appear on the face. The lesions cannot be hidden under clothing; each is prominently displayed and detracts significantly from one's personal appearance and self-esteem. Recently many of acne patients are visiting to Oriental Medicine Hospitals. They want to receive the treatment of acne related another disease and causes, or worry about side effects of antibiotics and hormone therapy. This study was performed at Pundang Cha Oriental Medicine Hospital Department of Dermatology from March 1, 1997 to February 29, 2000 in 31 patients with recurrent acne. We investigated the clinical findings, included distribution of age & sex, severity of acne, sites on face, related causes, duration of disease and causes of visiting Oriental Medicine Hospital and so on. The results were as follows : The peak age at onset was 20-29 years old in females with 16 cases reported. The 22 total cases patients had severe signs with most frequently sites being forehead & chin. They visited Oriental Medicine Hospital because they want to take the treatment of acne related with another body problems(12 cases) and worry about side effects of antibiotics. Twenty cases were diagnosed 肺熱血熱(20 cases). And given acupuncture treatment, herb-medication and sometimes we used external applications. Relatively, their satisfaction grade was high. Dermatologists are trying to treat new methods in order to remove scar and decrease sebaceous gland secretion,. And we, Oriental Medicine doctors, have to develop and offer to patients the most effective management and successful treatment of this disease.

• Clinics in Shoulder and Elbow
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• 제2권2호
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• pp.110-114
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• 1999

We reviewed the results of arthroscopic surgery in patients with rotator cuff disease. Arthroscopic subacromial decompression(ASD) was performed on 22 patients with rotator cuff disease who had not responded to nonoperative measures. In the patients who had a complete tear of the rotator cuff(four of ten Neer's stage III patients), mini-open repair also was performed. Results were determined by questioning patients about their satisfaction with the outcome of surgery and by functional assessment of the shoulder with the parameters of pain, function, and range of motion according to the UCLA shoulder rating scale. The average follow-up was 21 months. The results were sixteen(72%) excellent, three(14%) good, two(9%) fair, and one(5%) poor. The following variables were analyzed to assess their influence on final outcome; duration of preoperative symptoms, Neer's stage(extent of damage to the cuff), type of acromion. Satisfactory results were achieved in thirteen of fourteen patients(93%) who had duration of preoperative symptoms below one year, and in four of six(67%) above 2 years. And satisfactory results were achieved in eleven of twelve patients(92%) who had Neer's stage II and in eight of ten(80%) stage III and achieved in six of seven patients(86%) who had Bigliani's acromion type I, in nine of eleven(82%) type II, and in four of four(100%) type III. There are multiple factors that may influence the recovery after ASD or the eventual outcome. However, although there is still a controversy about the pathogenesis of rotator cuff disease, We found that arthroscopic subacromial decompression and mini-open repair in patients with rotator cuff disease were well enough documented to be considered a standard treatment.

• Journal of Preventive Medicine and Public Health
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• 제35권2호
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• pp.92-98
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• 2002

Objective : To estimate the burden of cardiovascular disease attributable to the total suspended particulates (TSP) and sulfur dioxide ($SO_2$) in Korea using the YLD (years lived with disability) measurement. Methods : Congestive heart failure(CHF) and myocardial infarction (MI) were chosen as the main cardiovascular diseases whose causes are attributable to the TSP and $SO_2$ levels. In order to calculate the YLD (years lived with a disability), the following parameters in the formula were estimated. : the incidence rate, the case fatality rate, The expected duration of a disability and the average age of onset were estimated. The expected duration of a disability and the average age of onset were calculated using the DISMOD method, as developed by the GBD researchers. The burden of cardiovascular disease due to TSP and $SO_2$ was estimated using the number of years that the patient lived with a disability. Results : The VLD of the CHF due to the TSP and $SO_2$ was attributed to the TSP (94.4 person-year) and $SO_2$ levels (35.0 person-year). The YLD of the ME due to the TSP and $SO_2$ was attributed to the TSP (148.4 person-year) and $SO_2$ levels(27.6 person-year). Conclusion : The YLD method employed in this study was appropriate for quantifying the burden of cardiovascular disease. Therefore, it would provide a rational basis for planning a national health policy regarding the disease burden of the risk factors in Korea.

• 기본간호학회지
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• 제13권2호
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• pp.249-256
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• 2006

Purpose: To investigate the influence of clinical and demographical variables on depression, instrumental activities of daily living (IADL), and cognitive function in patients with Parkinson's disease. Method: Using a structured questionnaire data were collected from 100 participants registered in the neurology department of C university hospital. Duration and stage of disease, fall history, vision impairment, duration and quality of sleep, orthostatic hypotension, ambulation impairment, and use of walking aid were included in clinical variables. Depression, IADL, and cognitive function were assessed using Kee's GDSSF-K, Cho's scale, and K-MMSE. Collected data were analyzed using the SAS program. Results: The depression score for the participants was 7.78, higher than cut-off score(5). Participants who were male, living with spouse, above high school education, high economic status, with no vision impairment, and no ambulation impairment revealed high cognitive scores. Average IADL score were significantly higher for participants who were male, who had high economic status, low stage of disease, and no ambulation impairment. Depression IADL & cognitive function scores were significantly different according to ambulation impairment. Scores for ADL and cognitive function were positively correlated. Conclusion: It is recommended that make programs for patients with Parkinson's disease, clinical and demographic variables should be considered according to their individual needs.

• The Journal of Korean Physical Therapy
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• 제31권2호
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• pp.122-128
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• 2019

Purpose: This study examined the effects of sagittal spinopelvic alignment on the clinical parameters, motor symptoms, and respiratory function in patients with mild to moderate Parkinson's disease (PD). Methods: This study was a prospective assessment of treated patients (n=28, Hoehn and Yahr (H&Y) stage 2-3) in a PD center. Twenty-eight subjects ($68.5{\pm}5.7yrs$) participated in this study. The clinical and demographic parameters, including age, sex, symptoms duration, treatment duration, and H&Y stage, were collected. Kinematic analysis was conducted in the upright standing posture with a motion capture system. A pulmonary function test (PFT) was performed in the sitting position using a spirometer. The motor symptoms were assessed on part III of the movement disorder society sponsored version of the unified Parkinson's disease rating scale (MDS-UPDRS). SPSS 18.0 was used to analyze the collected data. Results: The exceeding 12 degrees group of the lower trunk showed significantly higher on the clinical parameters than the below 12 degrees group. In addition, the exceeding 12 degrees group of the lower trunk showed a significantly lower forced expiratory volume at one second (FEV1) / forced vital capacity (FVC) (%) and 25-75% forced mid-expiratory flow (FEF) (L/s) than in the below group. On the other hand, there was no difference in the upper trunk and the cervical pelvis between the groups. Conclusion: These findings suggest that the sagittal balance in the lower trunk is related to the clinical parameters and respiratory function, but not the motor symptoms in patients with mild to moderate PD.

• Journal of Chest Surgery
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• 제5권2호
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• pp.159-164
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• 1972

Clinical observation is made in 29 cases of patients with esophageal cancer at Department of Chest Surgery in Chunnam University Hospital. 1] The prevalent age of male patient is fifth decade and of female is fourth and fifth decade. The average age of patient is 54 years old. 2] Duration of the disease before admission is relatively long, the duration within 7-9 months is 35% of all patients. 3] On the majority of patients, typical symptoms of esophageal cancer were manifested. 4] Operation was performed on 58% of all patients, in 23% curative and in 35% palliative resection was done.

• 기본간호학회지
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• 제10권3호
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• pp.276-282
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• 2003

Purpose: The purpose of this study was to investigate smoking history and quality of life in the patients with coronary artery disease (CAD). Method: Data were collected from 157 men who quit smoking or attempted to quit smoking. Quality of life was measured with the SCQoL(smoking cessation quality of life) scale which was developed by Olufade et al. (19?19), and includes 5 factors; social interactions, cognitive functioning, self control, anxiety, and sleep. Result: The patients usually smoking in their twenties (61.8%), continued to smoke for over 30 years (70.7%), and smoked 20-29 cigarettes a day (50.3%). The total mean scores for the SCQoL was $50.48{\pm}7.11$. Of the 5 factors, self control had the highest mean score ($17.00{\pm}3.79$). Patients who began smoking in their twenties had a higher SCQoL. However, there were no significantly differences in the SCQoL according to duration of smoking or amount of smoking per day. Conclusion: Age when smoking is begun is an important variable to explain SCQoL in patients with CAD. But, further study is needed to identify the influence of other variables such as duration and amount of smoking.

• Clinical and Experimental Pediatrics
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• 제56권2호
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• pp.75-79
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• 2013

Purpose: It has been reported that 10% to 20% of children with Kawasaki disease (KD) will not respond to intravenous immunoglobulin (IVIG) treatment. In this study, we aimed to identify useful predictors of therapeutic failure in children with KD. Methods: We examined 309 children diagnosed with KD at the Kyungpook National University Hospital and the Inje University Busan Paik Hospital between January 2005 and June 2011. We retrospectively reviewed their medical records and analyzed multiple parameters in responders and nonresponders to IVIG. Results: Among the 309 children, 30 (9.7%) did not respond to IVIG. They had significantly higher proportion of neutrophils, and higher levels of aspartate aminotransferase, alanine aminotransferase (ALT), total bilirubin, and N-terminal fragment of B-type natriuretic peptide than did responders. IVIG-nonresponders had a significantly longer duration of hospitalization, and more frequently experienced coronary artery lesion, and sterile pyuria. No differences in the duration of fever at initial treatment or, clinical features were noted. Conclusion: Two independent predictors (ALT${\geq}$84 IU/L, total bilirubin${\geq}$0.9 mg/dL) for nonresponse were confirmed through multivariate logistic regression analysis. Thus elevated ALT and total bilirubin levels might be useful in predicting nonresponse to IVIG therapy in children with KD.

• Journal of Chest Surgery
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• 제28권12호
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• pp.1132-1138
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• 1995

From 1991 to 1994, we experienced 24 cases of neonatal pneumothorax who were admitted to the Neonatal Intensive Care Unit[NICU , Chosun University Hospital. The Following results were obtained.1 The incidence of neonatal pneumothorax was 0.70%, and there were 8 spontaneous pneumothoraces and 16 secondary pneumothoraces. 2 The clinical manifestation of neonatal pneumothorax was as followed. Male infant was dominant[M:F=2:1 , the onset was within 24 hours in the majority[83% , and the right side[62% was more frequent than the left side. The gestation duration and birth weight show no correlation with underlying neonatal pneumothorax. The pulmonary diseases were meconium aspiration syndrome and hyaline membrane disease, and the incidence of those was 58%. Meconium aspiration syndrome occurred earlier than hyaline membrane disease. Symptoms and signs were tachypnea[46% , cyanosis[21% , irritability[13% , chest retraction[8% and apnea[8% .3 The treatments performed were oxygen therapy[17% , thoracentesis[4% and closed thoracostomy with underwater seal drainage[79% . The Mean duration of air leakage was 11.7 hours, and the mean drainage time was 4.35$\pm$1.3day. 4 The overall hospital mortality was 33%, and the rate of complication was 46%. The complications were metabolic acidosis, atelectasis, pleural effusion, pulmonary hemorrhage and pneumonia. We concluded that the prognosis was related to the underlying pulmonary disease.