• East Asian mathematical journal
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• v.35 no.1
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• pp.99-108
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• 2019

In this paper, we introduce a numerical approach to solve heat-diffusion equation with discontinuous diffusion coefficients in the three dimensional rectangular domain. First, we study the support operator method and suggest a new method, the continuous velocity method. Further, we apply both methods to a diffusion process for neurotransmitter release in an individual synapse and compare their results.