• Proceedings of the Korean Institute of Interior Design Conference
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• 2007.05a
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• pp.97-100
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• 2007

Because of the industrialization, the number of acquired handicapped people and chronic disable people is increasing. This phenomenon takes an increasing interest in the interior and environment of a lobby at the rehabilitation's hospitals. This study represents the basic information of an efficient use of spaces in the rehabilitation's hospitals through a research into the characteristics of universal designs in the rehabilitation's hospital lobbies from six hospitals which are located in Seoul and Kyung-gi area. According to the study result, although the handicapped people are accessible to the lobbies, the considerations of the hospital's facilities and their abilities are still insufficient.

• Proceedings of the Korea Contents Association Conference
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• 2011.05a
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• pp.263-264
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• 2011

본 연구에서는 한국인 표준체형과 유사한 사람의 의료 영상 자료를 이용하여 인체 골격계 모델을 개발하였다. 이를 동역학 해석 상용 소프웨트어인 RecurDynTM에 탑재하여 인체 시뮬레이션 모듈을 개발하였고 타당성을 검증을 거친 후 노인의 앉기-서기 및 보행 동작해석에 적용하였다. 노인이 보행기(elderly walker)를 사용하여 앉기-서기 동작을 할 때 하지관절 기구학의 변화는 미비하였으나 보행 시 각 관절의 가동범위가 감소하였고 동작시간이 증가하였다. 또한 근전도 해석결과 일부 발목 주변 근육들과 햄스트링 근육에서 근활성치가 줄거나 활성시간이 줄었다. 이러한 변화는 보행기를 이용한 보행 때 하지의 기여도가 감소했기 때문에 발생하는 현상으로 생각된다. 본 연구를 통해 얻어진 시뮬레이션 기술은 다양한 인체 정보 콘텐츠분야에 널리 활용될 것으로 생각된다.

• Bulletin of the Korean Chemical Society
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• v.34 no.12
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• pp.3782-3786
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• 2013

Non-small cell lung cancer (NSCLC) is the most common type of lung cancer and that accounts for 85% of lung cancer patients. Although several EGFR-targeted drugs have been developed in the treatment of NSCLC, the clinical efficacy of EGFR-targeted drugs in NSCLC is limited by the occurrence of drug resistance. In this regard, Hsp90 represents great promise as a therapeutic target of cancer due to its potential to simultaneously disable multiple signaling pathways. In this study, we discovered that a natural product, flavokawain B disrupted Hsp90 chaperoning function and impaired the growth of gefitinib-resistant non-small cell lung cancer (H1975). The result suggested that flavokawain B could serve as a potential lead compound to overcome the drug resistance in cancer chemotherapy.

• The Transactions of the Korean Institute of Electrical Engineers B
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• v.55 no.4
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• pp.224-230
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• 2006

The conventional way to implement a bidirectional converter with boost/buck has been to use two general purpose PWM ICs with a single supply voltage. In this case, when one direction mode is in operation, the other is disabled and the output of the error amplifier of the disabled IC may be saturated to a maximum value or zero. Therefore, during mode transition, a circuit which can disable the switching operation for a certain time interval is required making it impossible to get a seamless transition. In this paper, the limitations of the conventional 42V/14V bi-directional DC/DC converter implemented with general current mode PWM ICs with a single supply voltage are reviewed and a new current mode PWM controller circuit with a dual voltage system is proposed. The validity of the proposed circuit is investigated through simulation. and experiments.

• Proceedings of the Korean Society of Computer Information Conference
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• 2010.07a
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• pp.191-194
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• 2010

본 논문에서는 HFC 망에서 상향 대역의 잡음신호를 중심으로, 잡음신호 및 스펙트럼을 분석하여 HFC 전송망의 효율적 장애처리 방안을 제시한다. HFC망은 빠른 속도로 다양한 멀티미디어 서비스를 제공하는 장점에도 불구하고 동축 구간이 외부의 환경적 영향을 많이 받을 가능성과 상향 잡음의 유입으로 디지털 전송망에 비교하여 상대적으로 어려움이 있다. 따라서 본 연구는 유입잡음을 스펙트럼 분석하여 유형화함으로서 잡음신호의 원인에 따른 신속한 대처와 인적, 물적 자원 투입요소 최소화가 기대된다.

• Bulletin of the Korean Chemical Society
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• v.35 no.4
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• pp.1154-1158
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• 2014

Hsp90 is an ubiquitous molecular chaperone protein, which plays an important role in regulating maturation and stabilization of many oncogenic proteins. Due to its potential to simultaneously disable multiple signaling pathways, Hsp90 represents great promise as a therapeutic target of cancer. In this study, we synthesized flavokawain analogues and evaluated their biological activities against drug-resistant cancer cells. The study indicated that compound 1i impaired the growth of gefitinib-resistant non-small cell lung cancer (H1975), down-regulated the expression of Hsp90 client proteins including EGFR, Her2, Met, Akt and Cdk4, and upregulated the expression of Hsp70. The result strongly suggested that compound 1i inhibited the proliferation of cancer cells through Hsp90 inhibition. Overall, compound 1i could serve as a potential lead compound to overcome the drug resistance in cancer chemotherapy.

• Publications of The Korean Astronomical Society
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• v.30 no.2
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• pp.721-723
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• 2015

Astronomical outreach activities for the general public who are unfamiliar to astronomy is a challenging task. It requires creative thinking to solve the problem. The amateur astronomical clubs in a number of cities in Indonesia routinely schedule observations at public parks. The interaction between these clubs and formal education institutions is established by face to face interaction and assisted by social media. The physics teachers who took astronomy courses in university are potential resources to enlarge the outreach scope by creating astronomical clubs as an extracurricular activity. Recent progressive trends in astronomy dissemination for the disabled are also a great opportunity to assist the disabled in experiencing hands-on activities based on formal and informal education.

• Journal of the Korea Society of Computer and Information
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• v.20 no.10
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• pp.107-112
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• 2015

There are numerous hazards and toxins have been produced in many forms along with life and working environments. Nevertheless, to remove theses hazards and toxins, there are many counteracting goods manufactured, but the result is limited in specific categories. Also it costs a lot of energy waste. In this paper, we propose a model that reduce wasting energy for detecting and getting rid of the harms. It adds a multi hazards auto-detection model for user friendly include the disable. It will be controlled the minimal sensed level of the harms by individuals through the proposed model. It can conduct detecting and eliminating the harms via eco-sensors pack which is adapted in different environments. As a result, the model works to produce only essential energy to clear the hazard and toxins as soon as the harms are generated and it leads to standby power.

• The Transactions of The Korean Institute of Electrical Engineers
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• v.60 no.2
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• pp.309-314
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• 2011

Outer rotor type in-wheel switched reluctance motor for Welfare neighborhood electric vehicle is researched. In-wheel system is to drive the electric vehicle without mechanical transmission, shaft, differential gears or other mechanical system. To calculate drive power for each wheels, the elder's and disable's safety driving conditions are considered. The designed outer rotor SRM has a 6-stator and 8-rotor pole. The determined dimensions as well as the stator and rotor pole arc are simulated and tested with CAD and finite element analysis to verify the performance of the proposed motor.

• Proceedings of the Korean Institute of Interior Design Conference
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• 2008.05a
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• pp.247-250
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• 2008

As society and culture becomes complicated and diverse, so do the ensuing problems. The symptoms from the stress there was mainly focused on the adult group, however, now, they are shown in children. So the play therapy attracts attention as a way to cure stress. This study is intend to analysis an environment of play therapy space which would play an active role during treatment through the understanding of children's playing behavior. Disable children's playing therapy and pattern should be considered in the playing environmental design, and their feelings also need to be considered. The cozy and relaxed environment is important to children, so that they can have a natural interaction with the environment during the therapies. Output the factor of environment for play therapy and suggest the space of play therapy which fit on it.