• Human Ecology Research
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• v.58 no.1
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• pp.1-12
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• 2020

This study examined if the effect of family functioning on preschoolers' school readiness can be mediated by mothers' affective parenting and preschoolers' self-regulation in the year before children enter elementary school. This study analyzed the 7^th year data of panel study of Korean children collected by the Korean Institute of Child Care and Education. Statistical analysis included 1,513 pairs of 6-year-old children and mothers. Descriptive statistics analysis, correlation analysis, structural equation modeling, and bootstrapping analysis were conducted using SPSS 22 and Amos 20. The primary findings were as follows. First, the sub-factors of preschoolers' school readiness composed of children's social and emotional development, approach to learning, cognitive development and general knowledge, and communication were positively correlated with family functioning, mothers' affective parenting, and preschoolers' self-regulation. Second, the result of structural equation modeling showed that the indirect paths from family functioning to preschoolers' school readiness through mothers' affective parenting and preschoolers' self-regulation were significant, while the direct path was insignificant. Third, bootstrapping analysis showed that mothers' affective parenting and preschoolers' self-regulation fully mediated the relationship between family functioning and preschoolers' self-regulation. The findings provide the grounds for families and parents with preschool aged children to implement effective support practices to maintain a functional family system that can promote preschoolers' school readiness.

• Journal of Microbiology and Biotechnology
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• v.28 no.2
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• pp.181-189
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• 2018

Candida albicans is a major pathogenic fungus in humans, and meets at first the innate immune cells, such as macrophages, in its host. One important strategy of the host cell to kill C. albicans is to produce reactive oxygen species (ROS) by the macrophages. In response to ROS produced by the macrophages, C. albicans operates its defense mechanisms against them by expressing its oxidative stress response genes. Although there have been many research studies explaining the specific transcription factors and the expression of the oxidative stress genes in C. albicans, the regulation of the oxidative stress genes by chromatin structure is little known. Epigenetic regulation by the chromatin structure is very important for the regulation of eukaryotic gene expression, including the chromatin structure dynamics by histone modifications. Among various histone modifications, histone acetylation is reported for its direct relationship to the regulation of gene expression. Recent studies reported that histone acetyltransferases regulate genes to respond to the oxidative stress in C. albicans. In this review, we introduce all histone acetyltransferases that C. albicans contains and some papers that explain how histone acetyltransferases participate in the oxidative stress response in C. albicans.

• Journal of ILASS-Korea
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• v.6 no.1
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• pp.25-34
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• 2001

Several efforts to meet the exhaust gas regulation have been undertaken by many researchers in recent years. Main researches are on development of design techniques of intake port and combustion chamber, atomisation of fuel and precise control of air-fuel ratio, post-treatment of exhaust gas and so on. Engine technology is changed from PFI to GDI to correspond with exhaust gas regulation. GDI technique makes it possible to preserve lean air-fuel ratio and control accurate air-fuel ratio. Nevertheless, It is not cleared that information of spray characteristics and atomization process are very dependent on fluctuation of pressure and change of temperature in intake stroke. In this study, a constant volume combustion chamber is manufactured to investigate various fluctuations of in-cylinder pressure for injection duration. It is taken photographs of injection process of conventional GDI injector using PMAS. Then, it was verified experimently that ambient conditions as temperature and pressure of combustion chamber have effects on process of spray growth and atomization of fuel.

• Journal of Korean Clinical Nursing Research
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• v.21 no.1
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• pp.116-126
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• 2015

Purpose: The purpose of this study was to examine the relationship between social support (family, healthcare provider, friends/peer), treatment belief, hope, and health status in patients on hemodialysis, and to identify direct and indirect effects of the variables on patients' health status. Methods: The self-regulation model was used to establish a path model. Data were collected from 240 patients. Multidimensional Scale of Perceived Social Support, Revised Illness Perception Questionnaire, Herth Hope Index, and Medical Outcomes Study Short Form-12 were used. Data were analyzed using the SPSS and AMOS programs. Results: The model was supported by fit statistics ($x^2=3.33$, p=.343, GFI .995, RMSEA .021, AGFI .968, NFI .986, CFI .999, TLI .993). Family and friends/peer support showed a significant direct influence on hope, while healthcare provider support directly influenced treatment belief. Social support, treatment belief, and hope directly and indirectly influenced health status, explaining 28.7% of the variance. Conclusion: These results show mechanisms underlying connections between social support and health status by demonstrating impact of social support and showing treatment belief and hope as mediators between social context and outcomes. To promote health of patients on hemodialysis, it is necessary for patient, family, healthcare professional, and friends to collaborate.

• The Proceedings of the Korean Institute of Illuminating and Electrical Installation Engineers
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• v.11 no.6
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• pp.81-89
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• 1997

In order to achieve the zero voltage regulation of the output voltage, the function control law will be used. In the previous function control law, only the proportional controller is used and the stability of the closed loop system was not analyzed. In this paper, for the realization of the control law, a new method to retrieve the low frequency component of the inductor voltage is proposed and analyzed. The large signal closed loop characteristics are alos analyzed to ensure the stable operation of the system disturbances. By using the function control law in the control system, the effect of the disturbance of the supply voltage is reduced in 93.3% for the direct dusty ration method. Also, in the effect of the disturbance of the load current, the output voltage has a logn recovery-time and is changed proportionally in the direct duty ratio method, but has stable in the function control law. Finally, the analysis shows that the disturbance of the output voltage being due to the supply voltage variation can be eliminated completely and the closed loop output voltage is insensitive to the disturbance of the load current. Therefore, it is proved that by using the function control law, the switching power supply with zero-voltage regulation output voltage can be realized.

• Proceedings of the KIPE Conference
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• 1998.10a
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• pp.45-49
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• 1998

In this paper, the direct thrust control of PWM Inverter-fed Single-sided Linear Induction Motor (hereinafter referred to as "SLIM") is achieved with Space Vector control and PI control. The trembling of air gap length which is occured between the primary winding core and the secondaty structure of the SLIM must be minimized in order to get quick response characteristic. First, voltage equations of SLIM are shown on the suitable d-q axis equivalent circuits which analyze characteristics of the thrust and the normal force. Also, modeling and analysis of the d-q axis equivalent circuits are able to make robust transient thrust from the current regulation in the equivalent circuits. These results exemplified the direct drive of SLIM with the reference speed and thrust were verified by the experiments.periments.

• Anxiety and mood
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• v.18 no.2
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• pp.109-115
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• 2022

Objective : The purpose of this study was to examine the influence of subscales of emotional intelligence on empathy in first-year medical students. Methods : A total of 215 first-year medical students were eligible for this study. Demographic factors (age, sex, and medical school entrance type) and measures for emotional intelligence and empathy, such as the Wong and Law Emotional Intelligence Scale and the Interpersonal Reactivity Index, were included in the survey. The relationship between emotional intelligence and empathy was analyzed by multiple linear regression, adjusting for age, sex, and entrance type. Results : The female students' level of emotional intelligence was higher than the male students for the self-emotional appraisal (p=0.029) and others' emotional appraisal (p=0.006) subscales. Meanwhile, the graduate-entry students scored higher for the use of emotion (p<0.001) and regulation of emotion (p=0.010) subscales than the direct-entry students. For empathy, the female students revealed a higher score in empathic concern (p=0.009) than the male students, and graduate-entry students scored higher than the direct-entry students in perspective taking (p=0.004) and empathic concern (p<0.001). The multiple linear regression analysis has identified significant influences of subscales of emotional intelligence on empathy: others' emotional appraisal on perspective taking (p<0.001), self-emotional appraisal (p=0.035) and regulation of emotion (p=0.023) on fantasy, others' emotional appraisal (p<0.001) and use of emotion (p=0.020) on empathic concern, and self-emotional appraisal (p=0.033) and regulation of emotion (p<0.001) on personal distress. Conclusion : This study's findings suggest that emotional intelligence may affect empathy in medical students, which can have implications for developing educational strategies to enhance empathetic attitudes in medical students.

• Journal of Korea Technology Innovation Society
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• v.20 no.4
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• pp.939-969
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• 2017

The interest in social regulation and its influence on innovation are increasing as the society concerns more for environment and safety. There have been plenty of literature about the impact of social regulation on innovation and its mechanism. Majority of research have been influenced by or based on the famous Porter's hypothesis. However, majority of the literature focus on internal factors such as expected benefits from change of regulations, and it is hard to find one studying social regulation's influence on innovation through external factors such as market or industrial structure. This study addresses this issue of the impact of social regulation on innovation by analyzing the case of fire-retardant coating material for steel structure industry in Korea. It scrutinizes the impact of social regulation which affects competition and innovation on substitute competing market, and tries to reveal that there might exist the other path to innovation, besides the way that the expected benefit from compliance of regulation directly drives innovation. As a result of the case study, we have found that changes in social regulation may act like economic regulation and restructure the market segment and this effect may lead to innovation. It can be explained by the fact that expected benefits from compliance of regulation can be a direct source of innovation, as Porter suggested, but the change of industry structure and competitive strength caused by the change in social regulation can also act as a driving force of innovation.

• The Journal of the Korea Contents Association
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• v.13 no.10
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• pp.347-355
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• 2013

The purpose of this study was to investigate the mediating effect which may operate within peer attachment as well as any links which may exist ego-resilience and life satisfaction and self-regulation learning ability in adolescence. The participants in this research consisted of 2,351 middle school students. the main result were as follows: first, each of three ego-resilience and peer attachment had an influence upon life satisfaction and self-regulation learning ability albeit in different ways. second, life satisfaction had a direct influence on self-regulation learning ability. third, the mediating effect of life satisfaction between ego-resilience and peer attachment upon and self-regulation learning ability were significant. finally, the limitation of this study were discussed along with suggestion for further research.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.13
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• pp.5371-5376
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• 2015

Berberine (B1), isolated from stems of Coscinium fenestratum (Goetgh.) Colebr, was used as a principle structure to synthesize three phenolic derivatives: berberrubine (B2) with a single phenolic group, berberrubine chloride (B3) as a chloride counter ion derivative, and 2,3,9,10-tetra-hydroxyberberine chloride (B4) with four phenolic groups, to investigate their direct and indirect antioxidant activities. For DPPH assay, compounds B4, B3, and B2 showed good direct antioxidant activity ($IC_{50}$ values=$10.7{\pm}1.76$, $55.2{\pm}2.24$, and $87.4{\pm}6.65{\mu}M$, respectively) whereas the $IC_{50}$ value of berberine was higher than $500{\mu}M$. Moreover, compound B4 exhibited a better DPPH scavenging activity than BHT as a standard antioxidant ($IC_{50}=72.7{\pm}7.22{\mu}M$) due to the ortho position of hydroxyl groups and its capacity to undergo intramolecular hydrogen bonding. For cytotoxicity assay against human fibrosarcoma cells (HT1080) using MTT reagent, the sequence of $IC_{50}$ value at 7-day treatment stated that B1 < B4 < B2 ($0.44{\pm}0.03$, $2.88{\pm}0.23$, and $6.05{\pm}0.64{\mu}M$, respectively). Berberine derivatives, B2 and B4, showed approximately the same level of CAT expression and significant up-regulation of SOD expression in a dose-dependent manner compared to berberine treatment for 7-day exposure using reverse transcription-polymerase chain reaction (RT-PCR) assays. Our findings show a better direct-antioxidant activity of the derivatives containing phenolic groups than berberine in a cell-free system. For cell-based system, berberine was able to exert better cytotoxic activity than its derivatives. Berberine derivatives containing a single and four phenolic groups showed improved up-regulation of SOD gene expression. Cytotoxic action might not be the main effect of berberine derivatives. Other pharmacological targets of these derivatives should be further investigated to confirm the medical benefit of phenolic groups introduced into the berberine molecule.