• 한국동물위생학회지
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• 제32권4호
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• pp.335-341
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• 2009

Canine brucellosis produce abortions and infertility in dogs and is currently diagnosed by serological methods such as rapid slide agglutination test with 2-mercaptoethanol (2-ME RSAT) and immunochromatographic assay (ICA). Bacterial isolation is considered gold standard for Brucella diagnosis and the polymerase chain reaction (PCR) is an alternative method to bacterial isolation. A total of 36 whole blood samples were collected from dogs reared in area of Chuncheon and were subjected to serology (2-ME RSAT and ICA for B. canis, Rose Bengal test and C-ELISA for B. abortus), blood culture and 3 types of PCRs (BSCP31, 16s rRNA, and OMP-2). All blood samples were negative by serology and blood cultures. The BCSP31 and the OMP-2 PCR detected 5 samples were positive whereas the 16S rRNA PCR detected all samples were negative as serological methods and blood culture did. From the results observed in the present study, we conclude that 16S rRNA PCR could be used for direct PCR for canine blood samples.

• 대한간호학회지
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• 제7권2호
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• pp.107-116
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• 1977

It is a well accepted fact that mental and physical health of nurses has a direct bearing or influence in their practice in the nursing profession. Recently, with this view in mind, the study of the mental and physical health of nurses has attracted the attention of many especially those in research hospitals. According to Soon Hyang Cha(1974) a nurse in clinical practice or service has a daily energy consumption of 39% and San Cho Chun (1974) asserts that Nurses'duties are more demanding on her emotionally than on her nursing technical skills. Many more studies has been made to this effect, here and abroad and similarly stressed the importance of mental and physical health for nurses. This study was made in an attempt to analyze the trend or tendency of the mental and physical health of nurses by employing the Cornell Medical Index (CMI) method. The data has been collected from May 1977 to November 1977, 200 nurses from 8 University hospitals and 200 nurses from general hospitals in Seoul, Theses who participated were selected at random. The data were tabulated and comparison made. The results were as follows : 1. Among nurses, the analysis based on the length of experience, it is apparent that, the longer or more experience one ha s, the more complaints they have. 2 The longer the nurses are engaged in nursing practice, the more they have problems in their digestive, musculoskeletal, respiratory and nervous systems and are more prone to diseases, and get tired easier than those of shorter experience. But on the other hand it could be seen that younger nurses or nurses with less experience in the profession are more melancholic and prone to stress than those with longer experience.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제26권6호
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• pp.606-612
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• 2000

This study was performed to investigate the average anthropometric value of normal Korean men and women and to compare the preceding literatures. Additionally, average Korean profilogram was made to serve as a template for diagnosis of facial form. Eighty five Korean subjects(41 men, 44 women) aged between 21 to 26 were selected by members of the author's department on the basis of intact dentition and Class I occlusion without facial asymmetry. Frontal and lateral photographs were taken under standardized condition with digital camera. The image was magnified and adjusted according to the FH plane of cephalometric radiographs and digitized using personal computer. To compare the Western beauty, 25 esthetically pleasing female was selected to measure various angle and distance of the face. 1. It was possible to calculate the mean coordinate value of Korean normal samples which enables the direct visualization and comparison with the use of template. The method in this study was easy to applicate under the Microsoft $Windows^{(R)}$ bases. 2. Maxillary vertical hypoplasia, upper and lower lip protrusion was characteristics of Korean norms and relatively narrow alar base distance, less conspicuous nasal projection was observed. As the vermilion exposure and upper lip length was more than western norm, chin looks shorter than western. To compare the Korean and Western esthetically pleasing profile, facial convexity and nose was less conspicuous in Korean women.

• 동국한의학연구소논문집
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• 제1권
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• pp.209-236
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• 1992

The microculture XTT antiviral assay method is used to quantitate HIV-1 induced cytopathic effects as modulated by test substances. This relatively simple assay facilitated the safe and rapid determination of in vitro antiviral activity of selected chemicals as well as direct cytotoxicity. This experiment also confirmed that this system measures infection and subsequent viral replication in target cells and XTT formazan formations correlated with the accumulation of extracellular virions, as measured by quantitative HIV-1 induced syncytium foramtion. The present results with Glycyrrhizin using this in vitro culture system demonstrated that effective dose, EC50(the concentration at which increases XTT formazan production in infected cultures to 50% of that in untreated, uninfected controls) was 250ml. As comparison, AZT was included in this experiment and demonstrated that EC50 AZT of was 0.05g/ml, approximately 5,000 times more potent than Glycyrrhizin based on EC50 ratio's alone. However, this potency is limited by severe cytotoxicity of AZT, while Glycyrrhizin is approximately 16 times less toxic(IC50 of Glycyrrhizin 800 and AZT 51 g/ml). While AZT's anti-HIV-1 viral activity is mediated by inhibition of reverse transcriptase of the virus, Glycyrrhizin faild to demonstrate any inhibitory activity against reverse transcriptase. Further study is necessary in order to understand the precise mechanisms of Glycyrrhizin action against HIV-1 viruses. Althouth Glycyrrhizin is less effective antiviral agent than AZT, much less toxicity of Glycyrrhizin is desirable in terms of chronic treatment. Combination treatment of AZT and Glycyrrhizin may be therapeutically beneficial. Clinical effectiveness of two drug combination therapy for AIDS patient is unknown at this time. However, this experimental investigation presents the scientific rational basis for such therapeutic approach.

• 한국통신학회논문지
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• 제32권12B호
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• pp.728-734
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• 2007

본 논문에서는 최소 구축비용의 물리적 다중 보안 등급 네트워크 설계를 위한 GOSST 휴리스틱 메커니즘을 제안한다. 다중 보안 등급 네트워크상에서 각 노드는 원하는 보안 등급으로 다른 노드와 통신할 수 있다. 이를 위해서는 불법적인 물리적 접근을 통제할 수 있는 방법이 필요하다. 이러한 네트워크를 최소비용으로 구축하기 위해 GOSST 문제를 적용한다. 이 문제는 NP-Hard 영역이므로 현실적인 해를 얻기 위해서는 적절한 복잡도의 휴리스틱이 필요하다. 본 연구에서는 최소 구축비용의 물리적 다중 보안 등급 네트워크의 설계를 위해, 우리의 이전 거리 직접 GOSST 휴리스틱을 변형한 GOSST 휴리스틱 메커니즘을 제안한다. 이것은 실험 비교 대상인 G-MST에 대하여 평균 29.5%의 구축비용 절감을 보였다.

• 전자공학회논문지 IE
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• 제43권2호
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• pp.70-74
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• 2006

기존 DS-CDMA 시스템은 부가 백색 가우시안 잡음, 채널 왜곡 그리고 다중 사용자에 의한 간섭 잡음과 같은 환경에서 성능이 열화된다. 이런 성분들로 인하여, 수신기에서 PN 확산 코드의 자기 상관 값이 감소한다. 이 기술은 확산 코드의 상관성을 근거를 두고 있다. 본 논문에서는 상관성을 높이기 위해서, DS-CDMA와 chirp 변조를 결합한 binary chirp DS-CDMA 기술을 제안하였다. binary chirp 심볼은 좋은 상관값을 지닌다. 따라서 BC DS-CDMA systems이라고 부르고자 한다. 시스템의 성능을 평가하기 위해서, AWGN 잡음과 전력선상에 존재하는 할로겐 잡음에서의 성능을 비교 하였다. 시뮬레이션 결과 제안한 방법이 기존 방법보다 더 나은 성능을 가지고 있음을 알 수 있다.

• 한국기계가공학회지
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• 제19권8호
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• pp.56-63
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• 2020

The heat transfer phenomenon in the vicinity of the irradiated region of a focused laser beam of a DMT process greatly affects both the deposition characteristics of powders on a substrate and the properties of the deposited region. The goal of this paper is to investigate the heat transfer characteristics of a single bead deposition of Inconel 718 powders on S45C structural steel using a laser-aided direct metal tooling (DMT) process. The finite element analysis (FEA) model with a Gaussian volumetric heat flux is developed to simulate a three-dimensional transient heat transfer phenomenon. The cross-section of the bead for the FEA is estimated with an equivalent area method using experimental results. Through the comparison of the results of the experiments and those of the analysis, the effective beam radius of the bottom region of the volumetric heat flux and the efficiency of the heat flux model for different powers and travel speeds of the laser are predicted. From the results of the FEA, the influence of the power and the travel speed of the laser on the creation of a steady-state heat transfer region and the formation of the heat-affected zone (HAZ) in the substrate are investigated.

• Asian-Australasian Journal of Animal Sciences
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• 제13권5호
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• pp.641-644
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• 2000

In vitro true digestibility of cup-plant (Silphium perfoliatum L.) is higher than other alternative forages and comparative to alfalfa (Medicago sativa L.) even at the high neutral detergent fiber (NDF) concentration. This study was conducted to determine whether the digestion kinetic parameters of cup-plant could explain high in vitro true digestibility of cup-plant at the several NDF levels. Cup-plant and alfalfa were both collected in Arlington and Lancaster, Wisconsin to meet the NDF content within 40 to 50% range. The collected samples were incubated with rumen juice to investigate the digestion kinetics at 3, 6, 9, 14, 20, 28, 36, 48, and 72 h. Kinetics was estimated by the model $R=D_0\;e-k(t-L)+U$ where R is residue remaining at time t, and $D_0$ is digestible fraction, k is digestion rate constant, L is discrete lag time, and U is indigestible fraction. Parameters of the model were estimated by the direct nonlinear least squares (DNLS) method. Digestion rate and potential extent of digestion were not statistically different in either forage. However, alfalfa had shorter lag time (p<0.05). The indigestible fraction increased with maturation in alfalfa and in cup-plant (p<0.05). The ratio of indigestible fraction to acid detergent lignin (ADL) was higher in cup-plant than in alfalfa (p<0.05). From the results, alfalfa is probably digested more rapidly than cup-plant, however, cup-plant maintains higher digestibility with maturation due to a relatively slower increase of indigestible fraction in NDF.

• Asian Pacific Journal of Cancer Prevention
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• 제13권8호
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• pp.3863-3868
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• 2012

In this study mitochondrial D-Loop variations in Iranian prostate cancer and benign prostatic hyperplasia (BPH) patients were investigated. Tumour samples and corresponding non-cancerous prostate tissue from 40 prostate cancer patients and 40 age-matched BPH patients were collected. The entire mtD-loop region (16024-576) was amplified using the PCR method and products were gel-purified and subjected to direct nucleotide sequencing. A total of 129 variations were found, the most frequent being 263A${\rightarrow}$G and 310T${\rightarrow}$C among both BPH and prostate cancer patients. Variation of 309 C${\rightarrow}$T was significantly more frequent in prostate cancer patients (P value<0.05). Four novel variations were observed on comparison with the MITOMAP database. Novel variations were np16154delT, np366G${\rightarrow}$A, np389G${\rightarrow}$A and 56insT. There was no correspondence between the different variations and the age of subjects. Considering that D-loop variations were frequent in both BPH and prostate cancer patients in our study, the fact that both groups had high average age can be a possible contributing factor. D-loop polymorphisms and microsatellite instability can influence cell physiology and result in a benign or malignant phenotype. Significantly higher frequency of 309 C${\rightarrow}$T variation in cancer patients is a notable finding and must be a focus of attention in future studies.

• 한국HCI학회논문지
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• 제5권2호
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• pp.1-6
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• 2010

본 연구에서는 장애인이나 게이머를 위해 눈의 움직임과 머리의 움직임으로 제어가 가능한 헤드 마우스를 제안하였고, 제안한 마우스를 기존의 마우스와 비교하였다. 마우스 포인터의 이동은 머리 움직임의 회전각도 정보를 활용하였고, 클릭이나 더블 클릭의 이벤트는 눈의 깜빡임을 이용하였다. 기존의 각속도계를 이용한 마우스에서 적분으로 인한 누적오차는 적분을 하지 않고 데드 존을 갖는 비선형 상대 좌표계 방식을 통하여 해결하였고, 추가적으로 이동 거리와 가속도를 함께 고려하여 직관적인 마우스 포인터 제어가 가능하도록 하였다. 주변광의 영향을 최소화하도록 광원 제어 회로를 설계하여 외부 광원의 변화에도 마우스 이벤트 검출에 영향을 받지 않도록 하였다. 제안한 마우스를 응시점을 이용한 마우스(퀵글랜스)와 비교한 결과, 20회 클릭하는 실험에서는 약 21%, Dasher를 이용한 문자입력실험에서도 약 25%, 화상키보드를 이용한 문자입력 실험에서도 약 37% 짧은 입력 시간을 보였다. 그리고 카메라 마우스와의 비교에서도 제안한 헤드 마우스가 우수한 성능을 보였다.