• Journal of The Korean Society of Clinical Toxicology
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• v.13 no.1
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• pp.50-54
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• 2015

Podostroma cornu-damae is a rare species of fungus belonging to the Hyocreaceae family. Its fruit body is highly toxic, as it contains trichothecene mycotoxins. The morphology is similar to that of immature Ganoderma lucidum, making identification difficult for non-experts. We experienced such a case of a 56- year-old male who picked and consumed podostroma cornu-damae, and consumed. Later that day, he developed digestive system symptoms, including nausea, vomiting, and abdominal pain. He presented to the emergency room (ER), there were no abnormal physical findings, symptoms improved after gastric lavage, and the patient voluntarily discharged himself on the same day. The following day, as the symptoms gradually deteriorated, he was admitted via the ER. He was presented with severe pancytopenia, alopecia, desquamation of skin, and acute renal failure. He recovered without any complications after conservative care, antibiotics therapy, and granulocyte colony stimulating factor administration. The most commonly reported complications of podostroma cornu-damae intoxication were reported pancytopenia, infection, disseminated intravascular coagulation, acute renal failure, etc. since Prevention is especially important because its toxicity can be lethal and there is no particular treatment to date, prevention is especially important. Promotion and education for the public are needed.

• Korean Journal of Environmental Biology
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• v.31 no.4
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• pp.486-492
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• 2013

Recently, a new disease showing symptoms such as epidermal exfoliation and muscular necrosis occurred in cultured Korean catfish. Although the mortality of fishes was low but the economic damages owing to loss of commercial value were severe. The authors isolated the causative agent from diseased fish and observed pathological changes both in naturally and artificially infected fish. The causative bacteria was identified as Aeromonas veronii. Subsequently we observed the daily death and pathological symptoms of artificially infected fish with Aeromonas veronii. Symptoms of artificially infected fish were similar to those of naturally infected fish and all fish died within 7 days after infection. Histopathological changes on the naturally infected fish revealed severe congestion and necrotic degeneration in the liver, spleen and kidney. Some bacterial aggregates with inflammatory degeneration were observed in the heart, and congestion and fibrosis in the lamina propria of digestive tube were predominant. In artificially infected fish, skin erosion and necrotic degeneration of muscle tissue around injected region were particularly manifested. Degeneration of hepatocytes in liver and hyalic degeneration around ellipsoids in spleen were partially observed. However, there were no predominant signs in digestive tube in artificially infected fish.

• Journal of Technologic Dentistry
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• v.38 no.1
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• pp.37-49
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• 2016

Purpose: This research is performed through the analysis of the dental technology students' life-style factors of their daily lives that have a close relation with health, and the self-reported symptoms which are related to psychosomatic diseases, for the production of basic data for the change of life-styles and the development of educational programmes. Methods: This research has been performed through questionnaires from the beginning of October of 2014 till the end of November through the Dental Technology students of G-do, chosen by random sampling method after informed consent, where out of the 270 papers, 258 results were used for the analysis. Results: Firstly, the results of the research was as follows: Non-smokers accounted for 61.2%, student who did not do regular physical activities accounted for 50.4%, students who had sleeping hours of 6 to 7 hours accounted for 35.7%, students who eat snacks accounted for 63.2%, students who eat breakfast once to twice a week accounted for 30.6%, students who had an average number of drinks of once to twice a week accounted for 39.9%, and students with BMI of '$18.5^{\circ}{{\neq}}22.9$' accounted for 56.2%, being the highest. Secondly, in gender, smoking (p<.001), regular physical activity (p<.001), BMI (p<.001), eat snacks (p<.05), average number of drinks (p<.05), and of the health check-up, eat breakfast (p<.05), of the year level, eat snack (p<.01), BMI (p<.01), hours of sleep (p<.05), of major satisfaction, regular physical activity (p<.01), and BMI (p<.05), and there was a significant statistical difference, but there were no significant statistical difference in religion. Thirdly, of the bodily self-reported symptoms of the correlation analysis within the life-style variables and the self-reported symptoms, multiple subjective symptoms (I), respiratory (A), eye and skin (B), and digestive organs (C) were the highest in the correlation analysis with regular physical activity (p<.01), and of mental health, impulsiveness (H), mental instability (J), and depression (K) showed highest results in correlation analysis with regular physical activity (p<.01, p<.05), lie scale (L) and irregular and life (G) with eat breakfast (p<.01), and aggressiveness (F) with BMI (p<.01), showed highest results in correlation analysis. Fourthly of the Dental technology students' bodily self-reported symptoms, life-style factors which had a statistically significant effect appeared to be regular physical activity (p<.001) and BMI (p<.05), and of the mental self-reported symptoms, causes that did not have statistically significant effect appeared to be regular physical activity (p<.05) and eat breakfast (p<.05). Conclusion: This research concludes that in order to develop correct life-style habits for health promotion and reduce self-reported symptoms related to the Dental Technology students' diseases, education for the recognition of the necessity of self health promotion must be conducted, and a education programme scheme for the Dental technology curriculum for practicing the correct life-style habits in daily life is required.

• Journal of Sasang Constitutional Medicine
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• v.33 no.3
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• pp.1-15
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• 2021

Introduction The clinical usefulness of Sasang Digestive Function Inventory (SDFI) for analyzing Sasang type-specific pathophysiological symptom was illustrated repeatedly. It was revised to enhance its validity, reliability and clinical usefulness, however its clinical studies supporting these were not sufficient yet. Methods 193 healthy university students responded once to Nepean Dyspepsia Index-Korean (NDIK), Functional Dyspepsia-Related Quality of Life (FDQOL), and Dutch Eating Behavior Questionnaire (DEBQ), and twice to SDFI with four weeks of interval. The Body Mass Index (BMI) and Ponderal Index (PI) were also calculated. The 4-week test-retest reliability and correlation coefficients between NDIK, FDQOL, DEBQ, and SDFI were examined using Pearson's correlation. The significant differences between Sasang types in SDFI and its subscales were examined using ANCOVA with the age as covariate. Results The range of test-retest reliability for SDFI and its subscales was from 0.801 to 0.887. The SDFI-total correlated positively with BMI (r=0.323) and DEBQ-External Eating (r=0.433), while the SDFI-Digestion negatively with NDIK (r=-0.472) and FDQOL-total (r=-0.364). The SDFI-Habit correlated positively with BMI (r=0.310) and DEBQ-total (r=0.481), and the SDFI-Appetite with DEBQ-total (r=0.322). The SDFI-total, SDFI-Digestion, and SDFI-Habit scores of Tae-Eum type (35.6±6.25, 12.38±3.24 and 9.89±3.38, respectively) were significantly bigger than those of So-Eum type (29.84±8.31, 9.93±4.28 and 7.66±3.96). Discussion The SDFI was found to be an objective clinical measure with sufficient concurrent validity for measuring eating behavior and quality of life related to overeating and dyspepsia, and illustrated distinctive differences between Sasang types. It might be useful for the effective medical education and integrative medical practice.

• Journal of Gastric Cancer
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• v.20 no.3
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• pp.337-343
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• 2020

Distal gastrectomy with Billroth I or II reconstruction may cause duodenogastroesophageal reflux (DGER), thereby resulting in digestive or respiratory symptoms. The mainstay of treatment is medication with proton pump inhibitors. However, these drugs may have limited effects in DGER. Laparoscopic fundoplication has been proven to be highly effective in treating gastroesophageal reflux disease (GERD), but it cannot be performed optimally for GERD that develops after gastrectomy. We report the case of a 72-year-old man with a history of distal gastrectomy and Billroth I anastomosis due to early gastric cancer. GERD due to bile reflux occurred after surgery and was refractory to medical therapy. The patient underwent Roux-en-Y conversion from Billroth I gastroduodenostomy and hiatal hernia repair with only cruroplasty. Fundoplication was not performed. His symptoms improved significantly after the surgery. Therefore, laparoscopic hiatal hernia repair and Roux-en-Y conversion can be an effective surgical procedure to treat medically refractory DGER after Billroth I gastrectomy.

• Korean Journal of Clinical Pharmacy
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• v.7 no.1
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• pp.22-32
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• 1997

The gastrointestinal disorders (GI disorders) is one of the most common diseases in Korea. The community pharmacists are often faced with the complaints of symptoms due to the GI disorders. However the drugs used to treat the GI disorders are frequently abused by the patients themselves because these drugs are easily available and have high placebo effects. Therefore, we have reviewed the digestive diseases statistics of 1996 to find out the frequencies of the GI disorders in the outpatients of Samsung Medical Center. Using these statistic data, we figured out the frequently diagnosed GI disorders and analysed commonly used prescriptions from February 1st to 28th of 1997. In addition, we also evaluated the commonly used drugs in these prescriptions. About twenty thousands of patients visited the hopital because of their GI symptoms in 1996. It was found that dyspepsia, viral hepatitis, and gastric and duodenal ulcer disease are frequently diagnosed in these patients. In a point of view on other GI disorders, gastritis and duodenitis, irritable bowel syndrome, gastroesophageal reflux disease, constipation and diarrhea were commonly detected. And a number of drugs were prescribed to treat the GI disorders, which included the prokinetics, Histamine-2 receptor antagonists, proton pump inhibitor, antacids, tranquillizers, antidepressants, antispasmodics, laxatives and so on. Interestingly, there were many prescriptions composing of the antibiotic regimens to eradicate H. pylori which has been proven to cause peptic ulcers.

• Journal of Korean Medical classics
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• v.21 no.3
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• pp.147-155
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• 2008

Seopcheonsa(葉天士) regarded the cause of Stomach-Eum[胃陰] deficiency as the lack of fluid and humor induced the heat by Eum(陰, yin) deficiency constitution, external pathogen, overexertion and fatigue, misused medication etc. He said that the symptoms of Stomach-Eum deficiency was related to indigestion of food and that it induced the short supply of nutrition for the whole body and the symptoms by disabled Earth[土]-engenders-Metal[金]. He presented the treatment of clearing Stomach-Fire[胃熱] and nourishing Stomach-Eum[胃陰], and used Geumgwemaekmundongtang(金匱麥門冬湯). And he emphasized Stomach-Eum to supplement existing Spleen-Yang[脾陽] centered treatment. Dangjonghae(唐宗海) regarded Spleen-Eum[脾陰] as these, first, it was fluid and humor such as digestive enzyme. Secondly, it was nutritive substance itself. Finally, it contained plaster-oil and blood-agglutination which formed flesh with nutritive substance. Seopcheonsa and Dangjonghae both thought that fluid and humor was necessary to digest food. However, Dangjonghae's Spleen-Eum[脾陰] included nutritive substance as the result of digestion. So we can say that Dangjonghae integrated Spleen-Eum with Stomach-Eum and Spleen-nutrient.

• Journal of Society of Preventive Korean Medicine
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• v.17 no.1
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• pp.51-63
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• 2013

Objectives : This study aimed to investigate the current situation of Internet health counseling in Korean Medicine by analyzing the contents and pattern of the questions and answers in NAVER Jisik-iN. Methods : 1,121 questions answered by Korean Medicine doctors in NAVER Jisik-iN from January 2012 to June 2012 were extracted and analyzed. The contents and pattern of the questions and answers were classified. Then statistical analysis was performed and the research findings were compared with other studies. Results : Korean Medicine (KM) accounted for 1.73 percent of health counseling in NAVER Jisik-iN. Analyzing the questions and answers of KM counseling, questions about symptoms and answers providing medical knowledge were most common. The most frequently asked symptom was digestive disorder. Applying to Suchman's "Stage of Illness and Medical Care" model, 'the symptom-experience' stage took the first place. Conclusions : KM counseling in NAVER Jisik-iN has served as guidance for potential Korean Medicine consumers by providing medical knowledge about symptoms. For more effective guidance there should be a systematic Internet counseling system offering reliable information by KM doctors to meet the needs of medical consumers.

• Toxicological Research
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• v.28 no.3
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• pp.201-207
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• 2012

In order to evaluate the physical and psychological health effects from automobile air pollution, 99 employees who worked near a main street were given a general health questionnaire, and the prevalence of their subjective complaints was measured. The collected data were classified according to gender, sleep time, degree of regular exercise, self-consciousness of symptoms, length of employment, work time, rest time, and smoking status. The results obtained were summarized as follows: The scores related to health complaints regarding physical and psychological items were higher in females than in males. THI scores were higher for the < 4 hour sleep time group. The health complaint scores for physical items were higher in the regular exercise group, whereas most scores for mental items were higher in the irregular exercise groups. The health complaints scores for physical and psychological items were higher in the unhealthy symptom group than in other groups. Those employees who had worked for > 4 years showed significantly higher rates of complaints regarding the eyes and skin. THI scores were higher for the < 6 hour working time group. The smoking group showed higher scores regarding health complaints related to physical items. The THI scores of the respiratory organs, mouth, anus, and digestive organs were significantly higher for the smoking group than for the non-smoking group. In summary, this study shows that the health complaint scores regarding physical and psychological symptoms tended to be higher among the unhealthy group, the less sleep time group, the less work time group, smokers, and females. These results can be used to improve the psychosomatic health status and working environments of employees who work near a main street.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.15 no.1
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• pp.285-290
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• 2002

Urticaria is classified as Eunjin in Oriental Medicine. The intrinsic causes include digestive system disorder, food poison, parasite, female reproductive health problem, nervous breakdown, and disorder of endocrine hormone. The extrinsic sources include all kinds of insect bites or stings, medications, pollen, dirt, and toxic smells. Some unknown sources also produce urticaria. The urticaria that lasts for more than six weeks, is categorized as chronic urticaria which is not very different from acute urticaria that occurs rapid but for a short period. The chronic urticaria may come every day, and its symptoms can even get worse at irregular or regular intervals. The cycle is hard to predict. It could be weeks or years. In clinical treatments, the syndromes of patient's chronic urticaria with cerebral hemorrhage have been analyzed and identified as follows: The diagnosis by asking the patient's case history showed that the root cause was retention of food resulting from dysfunction of the spleen and stomach. First, Pyeongwisan was dosed. From the syndrome differentiation with four diagnostic methods, we diagnosed the symptoms as Poong yoel (wind-heat). Then, Hyeongbangpaedocksangamibang was prescribed to get very effective results.