• Journal of Chest Surgery
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• 제24권1호
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• pp.72-82
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• 1991

From May 1978 to Sep. 1990, 106 patients who had been diagnosed as primary lung cancer and operated on at the Department of Thoracic & Cardiovascular Surgery, Han Yang University, were clinically evaluated. 1. The peak incidence of age was 5th decade of life[37.7%] and 6th decade[29.2%]. Male to female ratio was 3.8: l. 2. Most of symptoms were respiratory, which were cough, chest pain, hemoptysis, and asymptomatic cases were 2.9%. 3. Histopathologic classifications were squamous cell carcinoma[53.7%], adenocarcinoma [23.8%], bronchioloalveolar cell carcinoma[6.6%], undifferentiated large cell carcinoma[6.6%], small cell carcinoma[3.8%], adenosquamous carcinoma[3.8%] and others[1.8%]. 4. Methods of operation were pneumonectomy 49.1%[52cases], lobectomy 21%[22cases] bilobectomy[6cases], lobectomy with wedge resection[3cases], exploration 21.9%[23cases], and resectability was 78.3%. 5. Staging classifications were Stage I [22.6%], Stage II [11.3%], Stage IIIa[42.6%], Stage IIIb[21.7%] and Stage lV[1.6%]. Resectability by Stage; Stage I was 100%, II 100%, IIIa 84.4% and IIIb 30.4%. 6. Causes of most of inoperable cases were invasion of mediastinal structures and diffuse chest wall, and others were contralateral lymph node invasion and malignant pleural effusion. 7. Operative mortality was 6.7% which caused by arrhythmia, sepsis, pulmonary edema, and radiation pneumonitis. 8. On the long term follow up of the resectable cases, overall 1 year survival rate was 58.5 %, 2 year 39%, and 5 year 19.5%. Five year survival rate was 40% in Stage I, 25% in Stage II and 11.7% in Stage Illa. As for the method of operation, the higher 5 year survival rate was observed in lobectomies[33.3%] than in pneumonectomies[10.3%].

• 천문학회보
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• 제37권2호
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• pp.107.1-107.1
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• 2012

We present the results of far-ultraviolet (FUV) observations of comet C/2001 Q4 (NEAT) obtained with Far-ultraviolet Imaging Spectrograph (FIMS) on board the Korean microsatellite STSAT-1, which operated at an altitude of 700 km in a sun-synchronous orbit. FIMS is a dual-channel imaging spectrograph (S channel 900-1150 ${\AA}$, L channel 1350-1750 ${\AA}$, ${\lambda}/{\Delta}{\lambda}$ ~ 550) with large image fields of view (S: $4^{\circ}.0{\times}4^{\prime}.6$, L: $7^{\circ}.5{\times}4^{\prime}.3$, angular resolution 5'-10') optimized for the observation of diffuse emission of astrophysical radiation. Comet C/2001 Q4 (NEAT) was observed with a scanning survey mode when it was located around the perihelion between 8 and 15 May 2004. Several important emission lines were detected including S I (1425, 1474 ${\AA}$), C I (1561, 1657 ${\AA}$) and several emission lines of CO $A^1{\Pi}-X^1{\Sigma}^+$ system in the L channel. Production rates of the notable molecules, such as C I, S I and CO, were estimated from the photon fluxes of these spectral lines and compared with previous observations. We compare the flux and the production rates in the radius of $3{\times}10^5$ km with $20{\times}10^5$ km from the central coma. We obtained L-channel image which have map size $5^{\circ}{\times}5^{\circ}$ The image was constructed for the wavelength band of L-channel (1350 - 1710 ${\AA}$. We also present the radial profiles of S I, C I, CO obtained from the spectral images of the central coma. The radial profiles of $2{\times}10^6$ km region are compared with the Haser model.

• 천문학회보
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• 제37권2호
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• pp.99.1-99.1
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• 2012

We report the results of our analysis of far ultraviolet (FUV) observations made for the broad region around the ${\alpha}$ Vir (Spica) including the interaction zone of the Loop I and the Local Bubble. We employed the datasets of the GALEX and the FIMS, which made observations at similar FUV wavelengths. First, we noted that the GALEX image was enhanced in the southern region where the interaction zone exists. We attribute this enhanced FUV emission to dust scattering of the stellar photons, mostly from the background field stars with small contributions from the central star Spica. While the region is optically thin in general, the FUV intensity did not correlate well with the dust extinction level, indicating that the local radiation field has significant fluctuations. On the other hand, the GALEX FUV intensity well with the $H{\alpha}$ intensity as well as the dust extinction level in the northern part. In fact, the neutral hydrogen column density correlated very well with the dust extinction level throughout the whole region in consideration. The relationship between the neutral hydrogen column density and the color excess was estimated to be ${\sim}7{\times}10^{21}atoms\;cm^{-2}$, which is a little higher than the previous observations made for a diffuse interstellar medium. The spectral analyses of the FIMS observations showed the enhanced C IV emission throughout the whole region, indicating that the C IV emission arises by the interaction of the hot gases with the shell boundaries. A simple model showed that a large portion of the C IV emission comes from the Loop I side of the interaction zone, compared to the Local Bubble side. The FIMS spectrum also showed indications of the molecular hydrogen fluorescence lines for the interaction zone.

• 천문학회보
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• 제46권1호
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• pp.50.2-51
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• 2021

Stars form exclusively in cold and dense molecular clouds. To fully understand star formation processes, it is hence a key to investigate how molecular clouds form out of the surrounding diffuse atomic gas. With an aim of shedding light in the process of the atomic-to-molecular transition in the interstellar medium, we analyze Arecibo HI emission and absorption spectral pairs along with TRAO/PMO 12CO(1-0) emission spectra toward 58 lines of sight probing in and around molecular clouds in the solar neighborhood, i.e., Perseus, Taurus, and California. 12CO(1-0) is detected from 19 out of 58 lines of sight, and we report the physical properties of HI (e.g., central velocity, spin temperature, and column density) in the vicinity of CO. Our preliminary results show that the velocity difference between the cold HI (Cold Neutral Medium or CNM) and CO (median ~ 0.7 km/s) is on average more than a factor of two smaller than the velocity difference between the warm HI (Warm Neutral Medium or WNM) and CO (median ~ 1.7 km/s). In addition, we find that the CNM tends to become colder (median spin temperature ~ 43 K) and abundant (median CNM fraction ~ 0.55) as it gets closer to CO. These results hints at the evolution of the CNM in the vicinity of CO, implying a close association between the CNM and molecular gas. Finally, in order to examine the role of HI in the formation of molecular gas, we compare the observed CNM properties to the theoretical model by Bialy & Sternberg (2016), where the HI column density for the HI-to-H2 transition point is predicted as a function of density, metallicity, and UV radiation field. Our comparison shows that while the model reproduces the observations reasonably well on average, the observed CNM components with high column densities are much denser than the model prediction. Several sources of this discrepancy, e.g., missing physical and chemical ingredients in the model such as the multi-phase ISM, non-equilibrium chemistry, and turbulence, will be discussed.

• 대한골관절종양학회지
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• 제16권1호
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• pp.27-36
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• 2010

목적: 색소 융모 결절성 활액막염은 슬관절을 비롯한 주요 관절에서 드물게 발생하는 연부 조직 종양으로서 수술 적 치료 후 재발 빈도가 높은 것으로 알려져 있다. 본 연구에서는 주요 관절에 발생한 미만형 색소 융모 결절성 활액막염에 대한 활막 전 절제술 후 임상 경과를 보고하고, 기존에 발표 된 문헌과 비교 분석하고자 한다. 대상 및 방법: 1994년 2월부터 2006년 3월까지 미만형 색소 융모 결절성 활액막염으로 치료 받은 21예의 환자를 대상으로 하였으며, 발생 부위는 슬관절 14예, 족관절 5예, 견주관절 2예가 있었다. 평균 추시 기간은 5년 5개월이었다(36-157개월). 발생 연령은 평균 34세였으며 남자가 7명, 여자가 14명이었다. 후향적 연구 방법으로 관절 운동 범위 측정을 포함한 정기적인 임상 양상 평가를 하였다. 결과: 총 21예의 미만형 환자 중 1예를 제외 한 전례에서 활막 전 절제술 및 전기소작술을 통한 보강 치료를 시행하였으며, 정기적인 외래경과 관찰 상 재발이 의심되었던 2예에서 재수술 후, 1예에서만 조직학적 재발이 확진 되었다. 활막 전 절제술을 시행하지 못한 1예와, 재발로 재수술 받은 1예에서 술 후 방사선 치료를 시행 하였다. 임상 기능 평가상 술전과 비교하여 모든 부분에서 통계적으로 유의한 호전이 있었다.(p<0.0001). 슬관절에 발생한 병변으로 수술적 치료를 시행 후 관절 운동 장애로 제약이 있던 환자는 2예(총 14예) 있었다. 결론: 최소 3년 이상의 추시 기간 동안 활막 전 절제술 및 전기 소작술을 통한 보강 치료로 호전된 임상 결과 및 낮은 재발율의 치료 효과를 얻을 수 있었다. 잦은 재발과 주요 관절에 발생하여 국소적 침투, 파괴로 기능 장애를 일으키는 미만형 색소 융모 결절성 활액막염에 치료에 있어 적절한 활막 전 절제술이 시행 될 경우 방사선 보강 치료는 제한 된 경우에만 필요할 것이다.

• Radiation Oncology Journal
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• 제3권2호
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• pp.113-121
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• 1985

1979년 2월부터 1982년 9월까지 서울대학교병원 치료방사선과에서 두경부에 국한된 Non-Hodgkin's Lymphoma환자중 근치적 방사선치료를 받은 54예를 대상으로 다음과 같은 결론을 얻었다. 1. 원발병소의 관해율은 완전관해가 $81\%$, 부분관해가 $19\%$이었다. 2. 2년 생존을 및 무병 생존율은 각각 $57\%,\;45\%$, 이었으며 병기별, 발생부위별, 임파절 종대의 앙측성 여부, 조직아형에 따라 생존율에 통제학적으로 유의한 차이가 있었다. 3. 재발율은 $54.5\%$(24예/44예)로 국소재발이 $29\%$, 원격전이가 $54\%$, 원격전이와 국소재발이 공존했던 경우가 $17\%$로 $92\%$가 2년이내에 재발하였다. 4. 원발병소의 크기가 6cm이상이지나 다발성인 경우, 원발병소가 임파절외 장기 또는 조직아형이 미만성이거나 대세포형인 경우 원격전이율이 높아 국소방사선치료후 전신적 항암요법의 추가치료가 고러되어야 한다.

• 한국농림기상학회지
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• 제4권2호
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• pp.95-102
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• 2002

관측밀도가 낮고 지형이 복잡한 산악지역을 대상으로 낮 시간대 기온의 경시변화를 기존의 방법으로 내삽할 경우 일사수광량의 불균일한 분포 때문에 심각한 추정오차가 발생할 수 있다. 이를 해결하기 위해 기존의 기온감율을 고려한 거리역산가중 내삽모형에 일사수광량 보정항을 추가하고 오차경감 정도를 평가하였다. 강원도 평창군 일대 14km$\times$22km 지역을 10m 해상도의 수치고도모형으로 표현하고, 각 격자점에 대해 태양과 지표면 사이의 기하학적 관계를 바탕으로 시간대별 실제 일사 수광량을 직달, 산란, 반사 등 성분별로 계산하였다. 수평면 일사량과의 편차를 산출한 다음 이 지역에서 경험적으로 얻은 일사-기온 변환당량을 적용하여 보정값을 얻었다. 기존의 방법에 의해 내삽된 기온값에 이 보정값을 적용하여 대상지역 전역의 기온분포도를 작성하였다. 대상 지역 내 경사향이 서로 다른 8개 지점에서 기온을 측정하여 기온분포도와 비교한 결과 추정오차가 크게 줄어들었음을 확인할 수 있었다.

• 대한환경공학회지
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• 제39권5호
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• pp.282-287
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• 2017

본 연구의 목적은 방사능 사고로 인한 오염물질 유입으로 인한 영향을 최소화하기 위한 제염제의 혼합확산장치 개발에 앞서 장치 가동으로 인한 혼합 및 확산영향을 예측하는데 있다. 유동특성분석을 위해 사용된 추적자는 방사성 동위원소는 Gy, To이며, 이를 검측하기 위해 2인치 NaI 방사선 검출기를 사용했다. 본 연구에 적용된 제염제 혼합확산장치의 임펠러는 3가지 type으로 제작하였다. 방사혼합형 임펠러는 상향류 흐름을 이용하여 수표면으로 확산이 가능하며, 최적의 조건을 찾기 위해 핀 구조를 조정하였다. 방사능 동위원소를 이용한 제염제 혼합확산장치의 유동특성을 분석한 결과, 모델별 혼합확산과 유동패턴특성을 획득하였다. Model 3 type은 별도의 Fin유도부와 보조 Fin이 구성되어 있어 다른 type의 임펠러보다 확산속도가 크고 완전혼합에 도달하는 시간이 짧게 나타났다.

• 생물환경조절학회지
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• 제25권2호
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• pp.123-132
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• 2016

The importance of energy saving technology for managing greenhouse was recently highlighted. For practical use of energy in greenhouse, it is necessary to simulate energy flow precisely and estimate heating/cooling loads of greenhouse. So the main purpose of this study was to develope and to validate greenhouse energy model and to estimate annual/maximum energy loads using Building Energy Simulation (BES). Field experiments were carried out in a multi-span plastic-film greenhouse in Jeju Island ($33.2^{\circ}N$, $126.3^{\circ}E$) for 2 months. To develop energy model of the greenhouse, a set of sensors was used to measure the greenhouse microclimate such as air temperature, humidity, leaf temperature, solar radiation, carbon dioxide concentration and so on. Moreover, characteristic length of plant leaf, leaf area index and diffuse non-interceptance were utilized to calculate sensible and latent heat exchange of plant. The internal temperature of greenhouse was compared to validate the greenhouse energy model. Developed model provided a good estimation for the internal temperature throughout the experiments period (coefficients of determination > 0.85, index of agreement > 0.92). After the model validation, we used last 10 years weather data to calculate energy loads of greenhouse according to growth stage of greenhouse crop. The tendency of heating/cooling loads change was depends on external weather condition and optimal temperature for growing crops at each stage. In addition, maximum heating/cooling loads of reference greenhouse were estimated to 644,014 and $756,456kJ{\cdot}hr^{-1}$, respectively.

• Journal of Korean Neurosurgical Society
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• 제30권3호
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• pp.334-341
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• 2001

Objective : We have currently changed treatment strategies to methotrexate(MTX)-based preirradiation chemotherapy with subsequent planned radiation for the initial therapy of primary central nervous system lymphoma (PCNSL). The aim of this study was to evaluate the results of treating PCNSL with chemotherapy plus radiotherapy (CRT) or radiotherapy(RT) alone. Method and Material : This study involved 10 females and 3 males patients with a mean age of 54.2 years. All patients underwent surgery, open(8 cases) or stereotactic biopsy(5 cases) for histological diagnosis. Eleven tumors were diffuse large B-cell lymphomas. Tumor volume change in the follow-up images and survival time were evaluated in patients treated with CRT and RT alone. In the beginning, two patients received ProMACE-Cytabom chemotherapeutic regimen, but did not complete the course and died of progressive tumor 8 and 9 months after diagnosis, respectively. One patient died at 6 months before chemotherapy. These three were excluded from the survival analysis. Five patients(RT group) completed full courses of cranial irradiation with or without boost. For the current combined modality treatment, high-dose MTXbased chemotherapy(systemic and intrathecal MTX, IV vincristine, and oral procarbazine) followed by whole brain irrdiation to 45Gy to tumor was introduced in 5 patients of CRT group. Result : A complete response was achieved in three of five who received RT only and in all of five who received CRT. All patients in CRT groups are in disease free status at a mean 23 months following therapy. The RT group patients refused any additional salvage therapy at tumor relapse and survived at mean 20 months from diagnosis. The Karnofsky performance status improved in eight of ten patients with treatment. The treatment toxicity included leukoencephalopathy in RT group and severe leukopenia, transient hepatitis, avascular necrosis of femoral head, hearing loss, and amenorrhea in CRT group, respectively. Conclusion : The combined modality therapy of MTX-based chemotherapy plus radiotherapy for PCNSL may enhance tumor response and improve patient survival. The patients who received CRT should be carefully followed up because of the higher risk of treatment-induced late neurotoxicity.