• 제목/요약/키워드: differential-basis

검색결과 421건 처리시간 0.029초

Modeling of temperature distribution in a reinforced concrete supertall structure based on structural health monitoring data

  • Ni, Y.Q.;Ye, X.W.;Lin, K.C.;Liao, W.Y.
    • Computers and Concrete
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    • 제8권3호
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    • pp.293-309
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    • 2011
  • A long-term structural health monitoring (SHM) system comprising over 700 sensors of sixteen types has been implemented on the Guangzhou Television and Sightseeing Tower (GTST) of 610 m high for real-time monitoring of the structure at both construction and service stages. As part of this sophisticated SHM system, 48 temperature sensors have been deployed at 12 cross-sections of the reinforced concrete inner structure of the GTST to provide on-line monitoring via a wireless data transmission system. In this paper, the differential temperature profiles in the reinforced concrete inner structure of the GTST, which are mainly caused by solar radiation, are recognized from the monitoring data with the purpose of understanding the temperature-induced structural internal forces and deformations. After a careful examination of the pre-classified temperature measurement data obtained under sunny days and non-sunny days, common characteristic of the daily temperature variation is observed from the data acquired in sunny days. Making use of 60-day temperature measurement data obtained in sunny days, statistical patterns of the daily rising temperature and daily descending temperature are synthesized, and temperature distribution models of the reinforced concrete inner structure of the GTST are formulated using linear regression analysis. The developed monitoring-based temperature distribution models will serve as a reliable input for numerical prediction of the temperature-induced deformations and provide a robust basis to facilitate the design and construction of similar structures in consideration of thermal effects.

miR-205 in Situ Expression and Localization in Head and Neck Tumors - a Tissue Array Study

  • Ab Mutalib, Nurul-Syakima;Lee, Learn-Han;Cheah, Yoke-Kqueen
    • Asian Pacific Journal of Cancer Prevention
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    • 제15권21호
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    • pp.9071-9075
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    • 2014
  • Background: microRNAs are small non-coding RNA that control gene expression by mRNA degradation or translational inhibition. These molecules are known to play essential roles in many biological and physiological processes. miR-205 may be differentially expressed in head and neck cancers; however, there are conflicting data and localization of expression has yet to be determined. Materials and Methods: miR-205 expression was investigated in 48 cases of inflammatory, benign and malignant tumor tissue array of the neck, oronasopharynx, larynx and salivary glands by Locked Nucleic Acid in situ hybridization (LNA-ISH) technology. Results: miR-205 expression was significantly differentially expressed across all of the inflammatory, benign and malignant tumor tissues of the neck. A significant increase in miR-205 staining intensity (p<0.05) was observed from inflammation to benign and malignant tumors in head and neck tissue array, suggesting that miR-205 could be a biomarker to differentiate between cancer and non-cancer tissues. Conclusions: LNA-ISH revealed that miR-205 exhibited significant differential cytoplasmic and nuclear staining among inflammation, benign and malignant tumors of head and neck. miR-205 was not only exclusively expressed in squamous epithelial malignancy. This study offers information and a basis for a comprehensive study of the role of miR-205 that may be useful as a biomarker and/or therapeutic target in head and neck tumors.

Identification of Proteins Responsible for the Development of Adriamycin Resistance in Human Gastric Cancer Cells Using Comparative Proteomics Analysis

  • Yang, Yi-Xuan;Hu, Huai-Dong;Zhang, Da-Zhi;Ren, Hong
    • BMB Reports
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    • 제40권6호
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    • pp.853-860
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    • 2007
  • Resistance to anticancer drugs is a major obstacle in the effective treatment of tumors. To understand the mechanisms responsible for multidrug resistance (MDR), a proteomic approach was used to identify proteins that were expressed in different levels by the adriamycinresistant human gastric cancer cell line, SGC7901/ADR, and its parental cell line, SGC7901. Two-dimensional gel electrophoresis (2-DE) and image analysis was used to determine which protein spots were expressed in different levels by the two cell lines. These spots were then partially identified using ESI-Q-TOF mass spectrometry, and the differential expressional levels of the partially identified proteins were then determined by western blot analysis and real-time RT-PCR. Additionally, the association of Nucleophosmin (NPM1), a protein that was highly expressed by SGC7901/ADR, with MDR was analyzed using siRNA. As a result of this study, well-resolved, reproducible 2-DE patterns of SGC7901/ADR and SGC7901 were established, and 16 proteins that may playa role in the development of thermo resistance were identified. Additionally, suppression of NPMl expression was found to enhance adriamycin chemosensitivity in SGC7901/ADR. These results provide a fundamental basis for the elucidation of the molecular mechanism of MDR, which may assist in the treatment of gastric cancer.

N-Tert-butylbenzothiazole-2-sulfenamide의-S-N = 결합에 대한 전기화학적 환원 (Electrochemical Reduction on the -S-N= Bond of N-Tert-butylbenzothiazole-2-sulfenamide)

  • 김해진;정근호;최규원;김일광;임선영
    • 대한화학회지
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    • 제35권6호
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    • pp.673-679
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    • 1991
  • N-Tert-butylbenzothiazole-2-sulfenamide (TBBS;가황촉진제)의 전기화학적 환원을 직류와 시차펄스 폴라로그래피, 순환 전압전류법, 조절전위 전기량법으로 연구하였다. TBBS의 전극환원과정은 단일 환원파(-2.31 volts vs. Ag/0.1M AgN$O_3$)에서 비가역으로 4전자가 이동하는 E-C-E-C 반응기구로 진행되었다. 조절전위 전기분해 결과 sulfenamide(-S-N=)결합이 끊어지고 mercaptobenzothiazole (MBT)과 유리된 황 그리고 benzothiazole disulfide (MBT dimer) 등이 생성물로 얻어졌다. 생성물의 분석결과와 pH변화에 따른 폴라로그램의 해석을 바탕으로 전기화학적 반응기구를 제안하였다.

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N-Oxyldiethylenebenzothiazole-2-sulfenamide의 -S-N= 결합에 대한 전기화학적 환원 (Electrochemical Reduction on the -S-N= Bond of N-Oxyldiethylenebenzothiazole-2-sulfenamide)

  • 김해진;정근호;최규원;김일광;임선영
    • 대한화학회지
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    • 제35권6호
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    • pp.680-688
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    • 1991
  • N-Oxyldiethylenebenzothiazole-2-sulfenamide (ODBS;가황산촉진제)의 전기화학적 환원을 직류와 시차펄스 폴라로그래피 순환 전압전류법, 조절전위 전기량법으로 연구하였다. ODBS의 전극환원과정은 단일 환원파(-1.86 volts vs. Ag/0.1 M AgN$O_3$in AN)에서 비가역으로 3전자가 이동하는 E-C-E-C 반응 메카니즘으로 진행되었다. 조절전위 전기분해 결과 SULFENAMIDE(-S-N=) 결합이 끊어지고 mercaptobenzothiazole(MBT)과 benzothiazole disulfide(MBT dimer) 그리고 유리된 sulfur 등이 생성물로 얻어졌따. pH 변화에 따른 폴라로그램의 해석과 생성물 분석의 결과를 바탕으로하여 전기화학적 반응 메카니즘을 제안하였다.

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InSAR Signature 시계열 분석을 통한 토지피복분류 (The Application of InSAR Signature Time Series for Landcover Classification)

  • 윤혜원;최윤수;윤하수;고종식;조성길
    • Spatial Information Research
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    • 제22권1호
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    • pp.27-33
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    • 2014
  • SAR 영상은 관측시간과 기상현상 등의 외부 환경 영향을 받지 않고 수시로 데이터 취득이 가능하며 광학영상보다 광범위한 관측 영역을 포함하기 때문에 레이더간섭기법 (InSAR)을 이용한 토지피복분류 기법은 큰 이점을 갖는다. 본 연구에서는 L밴드 ALOS PALSAR의 후방산란계수와 긴밀도를 이용한 새로운 토지피복분류 기법을 개발하고 최근 화산 폭발 가능성으로 인해 주목받고 있는 백두산 지역에 시험 적용하였다. 새로운 토지피복분류 체계는 ALOS PALSAR의 HH, HV편광 모드의 영상을 InSAR 시계열 상에서 패킷의 형태로 재구성하고 주성분 분석을 도입하여 분류의 신뢰도 향상을 시도하였다. 또한 MODIS 등 광학 영상 기반 분류와 상호 검증하여 정확도를 확인하였다.

항공사 여승무원 유니폼에 관한 이미지 연구 (A Study on the Image of Uniforms of Female Flight Attendants)

  • 이화진;김윤경;이경희
    • 한국의류학회지
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    • 제29권9_10호
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    • pp.1265-1273
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    • 2005
  • The objective of this study is to examine the images of the current uniforms and to provide the basic references in designing female flight attendants uniforms. In Incheon International Airlines, 11 of the major airlines with the most passengers along with the highest capacity were chosen and 22 pieces of photographs were collected, two photos coming from each airline companies. The semantic differential scale has been formed by 16 pairs of adjectives. Then, it has conducted a statistical analysis using a SPSS WINDOWS that contains 475 copies of the selected questionnaires (375 of the non-flight attendants, and 100 of the female flight attendants). The following are the results and the conclusion of this study. According to this study, four main components of the uniforms of the female flight attendants were attractiveness, femininity, noticeability, and activity, which have occupied $65.9\%$ of the total variance. It was concluded that attractiveness and femininity were two main factors in perceiving the females' uniforms. According to the results of the uniform image difference, it was shown that Asiana Airline's uniform is the most attractive and Cathay Pacific Airline uniform is the most feminine. The most noticeable uniform was from Singapore airline which included cultural and traditional components of its own national colors. Pants suits of Lufthansa airline and Northwest airline were shown as the most active uniforms. There were significant differences in uniform images according to subjects' gender, age, education, and occupation. Men perceived uniforms more attractive, feminine, and active than women. People over 40 perceived uniforms more attractive, feminine, and active, and the High School graduates perceived uniforms more feminine and active. On occupational basis, Federal workers and Educators perceived uniforms more active on uniforms. Passengers who take planes once a month perceived uniforms more attractive, feminine, and active.

Comparative proteome analysis of seeds of proso millet (Panicum miliaceum) cultivars

  • Roy, Swapan Kumar;Kwon, Soo Jeong;Park, Hyeong-Jun;Yu, Je-Hyeok;Sarker, Kabita;Cho, Seong-Woo;Jung, Tae-Wook;Park, Cheol-Ho;Woo, Sun-Hee
    • 한국작물학회:학술대회논문집
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    • 한국작물학회 2017년도 9th Asian Crop Science Association conference
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    • pp.120-120
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    • 2017
  • Since the composition of proteins from the Korean cultivars of Proso millet is unknown; thereby, the present study was conducted to obtain a reference map of millet seed proteins and identify the functional characteristics of the identified proteins. Proteins extracted from the millet seeds of various cultivars, were investigated using proteomic techniques as 2D electrophoresis coupled with mass fingerprinting. The 1152 (differentially expressed) proteins were detected on 2-D gel. Among them, 26 reproducible protein spots were analyzed by MALDI-TOF-TOF mass spectrometry. Out of 26 proteins, 2 proteins were up-regulated towards all cultivars of millet, while 7 proteins were up-regulated and 13 proteins were down-regulated against only one cultivar. However, abundance in most identified protein species, associated with metabolism, transcription and transcription was significantly enhanced, while that of another protein species involved in polysaccharide metabolism, stress response and pathogenesis were severely reduced. Taken together, the results observed from the study suggest that the differential expression of proteins from the four cultivars of millet may be cultivar-specific. Taken together, a proteomic investigation of millet seeds from different cultivars, we sought to better understand the genetic variation of millet cultivars representing the future millet research, and the functional categorization of individual proteins on the basis of their molecular function.

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구강내 접근법을 이용한 비순낭종의 치료 경험 (Clinical Experience with Nasolabial Cysts Using the Sublabial Approach)

  • 권준성;최환준;최창용;박재홍;박래경;김숙
    • Archives of Plastic Surgery
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    • 제38권3호
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    • pp.251-256
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    • 2011
  • Purpose: A nasolabial cyst is a rare non-odontogenic, soft-tissue, developmental cyst arising anywhere on the face inferior to the nasoalar region. It is thought to arise from either epithelial remnants trapped along the lines of fusion during the development of face or the remnants of the developing nasolacrimal duct. This study examines various features of nasolabial cysts with bony involvement to provide a basis for correct diagnosis and treatment. Methods: Eight cases of nasolabial cyst treated in Soonchunhyang Hospital between March 2002 and July 2010 were examined in terms of their clinical features and radiological and histological findings. Seven patients underwent surgical excision of the cyst via an intraoral, sublabial approach. One underwent incision and drainage. Results: Our eight patients were seven women and one man. The most frequent symptoms and signs were facial deformity and swelling of the nasolabial fold. Computed tomography (CT) showed a well-circumscribed cystic mass lateral to the pyriform aperture. Seven cases had erosive lesions on CT, and the intraoperative findings were consistent with a nasolabial cyst with a bony defect. Typical histopathological findings showed that these cysts were most frequently lined with respiratory epithelium with ciliated columnar cells and cuboid cells. No patient developed complications or recurrences. Conclusion: A nasolabial cyst is often unrecognized or confused with other intranasal masses, including fissural and odontogenic cysts, midface infections, or swelling in the nasolabial area. Therefore, a careful clinical and radiological evaluation should be preformed when considering the differential diagnosis. We present eight patients with nasolabial cysts treated via a gingivobuccal approach with excellent functional and cosmetic results.

지역특성을 고려한 수질오염총량관리 안전부하량 적용 (Application of Margin of Safety Considering Regional Characteristics for the Management of Total Maximum Daily Loads)

  • 박준대;오승영;김용석
    • 한국물환경학회지
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    • 제30권3호
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    • pp.351-360
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    • 2014
  • The allocation of margin of safety (MOS) at a uniform rate to all areas of the unit watershed makes it very difficult to keep the load allotment stable in the area for lack of reduction measures like forest land. This study developed an equation to calculate margin of safety differentially according to the regional characteristics. The equation was formulated on the basis of the regional characteristic factors such as a load contribution factor for land use type and a site conversion factor for the unit watershed. The load contribution factor represents a contribution of loads from a particular land use. The site conversion factor was derived from the site conversion ratio of a unit watershed. Margin of safety for the non-point pollution load in the land use sector decreased by 20~25% in three river basins. The margin of safety in the unit watersheds with low site occupation ratios decreased in high rate, while in the unit watersheds with large urban area decreased in low rate. With the application of the differential margin of safety considering regional characteristics, not only the reduction of pollution loads can become lighter but also it can be easier to develop plans for Total Maximum Daily Loads (TMDLs) even where the reduction measures are not available.