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The Effect of PET Scan Time on the Off-Line PET Image Quality in Proton Therapy (양성자 치료에서 영상 획득 시간에 따른 Off Line PET의 효율성 검증)

  • Hong, Gun-Chul;Jang, Joon-Yung;Park, Se-Joon;Cha, Eun-Sun;Lee, Hyuk
    • The Korean Journal of Nuclear Medicine Technology
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    • v.21 no.2
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    • pp.74-79
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    • 2017
  • Purpose Proton therapy can deliver an optimal dose to tumor while reducing unnecessary dose to normal tissue as compared the conventional photon therapy. As proton beams are irradiated into tissue, various positron emitters are produced via nuclear fragmentation reactions. These positron emitters could be used for the dose verification by using PET. However, the short half-life of the radioisotopes makes it hard to obtain the enough amounts of events. The aim of this study is to investigate the effect of off-line PET imaging scan time on the PET image quality. Materials and Methods The various diameters of spheres (D=37, 28, 22 mm) filled with distilled water were inserted in a 2001 IEC body phantom. Then proton beams (100 MU) were irradiated into the center of the each sphere using the wobbling technique with the gantry angle of $0^{\circ}$. The modulation widths of the spread out bragg peak were 16.4, 14.7 and 9.3 cm for the spheres of 37, 28 and 22 mm in diameters respectively. After 5 min of the proton irradiation, the PET images of the IEC body phantom were obtained for 50 min. The PET images with different time courses (0-10 min, 11-20 min, 21-30 min, 31-40 min and 41-50 min) were obtained by dividing the frame with a duration of 10 min. In order to evaluate the off-line PET image quality with the different time courses, the contrast-to-noise ratio (CNR) of the PET image calculated for each sphere. Results The CNRs of the sphere (D=37 mm) were 0.43, 0.42, 0.40, 0.31 and 0.21 for the time courses of 0-10 min, 11-20 min, 21-30 min, 31-40 min and 41-50 min respectively. The CNRs of the sphere (D=28 mm) were 0.36, 0.32, 0.27, 0.19 and 0.09 for the time courses of 0-10 min, 11-20 min, 21-30 min, 31-40 min and 41-50 min respectively. The CNR of 37 mm sphere was decreased rapidly after 30 min of the proton irradiation. In case of the spheres of 28 mm and 22 mm, the CNR was decreased drastically after 20 min of the irradiation. Conclusion The off-line PET imaging time is an important factor for the monitoring of the proton therapy. In case of the lesion diameter of 22 mm, the off-line PET image should be obtained within 25 min after the proton irradiation. When it comes to small size of tumor, the long PET imaging time will be beneficial for the proton therapy treatment monitoring.

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A Study of the Diffusion and Rise of Stack Plumes at Coastal Region by Using LIDAR Observation Data

  • Yoon, Ill-Hee
    • International Union of Geodesy and Geophysics Korean Journal of Geophysical Research
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    • v.26 no.1
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    • pp.43-58
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    • 1998
  • The Kwinana Shoreline Fumigation Experiment (KSFE) took place at Fremantle, WA, Australia between January 23 and February 8, 1995. The CSIRO DAR LIDAR measured plume sections from near the Kwinana Power Station (KPS) stacks to up to about 5 km downstream. It also measured boundary layer aerosols and the structure of the boundary layer on some occasions. Both stages A and C of KPS were used as tracers at different times. The heart of the LIDAR system is a Neodymium-doped Yttrium-aluminum-garnet (Nd:YAG) laser operating at a fundamental wavelength of 1064 nm, with harmonics of 532 nm and 355 nm. For these experiments the third harmonic was used because the UV wavelength at 355 nm is eye safe beyond about 50 m. The laser fires a pulse of light 6 ns in duration (about 1.8 m long) and with an energy (at the third harmonic) of about 70 mJ. This pulse subsequently scattered and absorbed by both air molecules and particles in the atmosphere. A small fraction of the laser beam is scattered back to the LIDAR, collected by a telescope and detected by a photo-multiplier tube. The intensity of the signal as a function of time is a measure of the particle concentration as a function of distance along the line of the laser shot. The smoke plume was clearly identifiable in the scans both before and after fumigation in the thermal internal boundary layer (TIBL). Both power station plumes were detected. Over the 9 days of operation, 1,568 plumes scans (214 series) were performed. Essentially all of these will provide instantaneous plume heights and widths, and there are many periods of continuous operation over several hours when it should be possible to compile hourly average plume statistics as well. The results of four days LIDAR observations of the dispersion of smoke plume in the TIBL at a coastal site are presented for the case of stages A and C.

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A Study on the Behavior of the Plane Stress Fracture Toughness - About the Compact Tension Specimen- (平面應力 破壞靭性値 擧動에 관한 硏究)

  • 송삼홍;고성위
    • Transactions of the Korean Society of Mechanical Engineers
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    • v.10 no.6
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    • pp.937-946
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    • 1986
  • In this paper, the plane stress fracture toughness of low carbon steel with 3mm thickness is investigated for various specimen widths and crack ratios using the J integral. The experiments is carried out for the compact tension(CT) specimen on an Instron machine. For materials that may be approximated by the Ramberg and Osgood stress strain law, the relevant crack parameter like the J integral and load line displacement are approximately normalized. Crack driving forces in terms of J integral is computed using the above estimation scheme. Abtained results are summarized as follows. (1) The plane stress fracture toughness, J$_{c}$, is almost constant in the range 50-70mm of width. Hence J$_{c}$ can be obtained by using smaller specimen than ASTM standard. (2) Yoon's and Simpson's formular which considers crack growth in obtaining J integral show more consevative J than Rice's and Merkle's (3) J$_{c}$ is almost constant in the range 0.499-0.701 crack ratios tested. J$_{c}$ obtained by using Kumar's formular is 28.14kgf/mm for base metal specimen and 32.51kgf/mm for annealed. (4) Comparison of the prediction with actual experimental measurements by Yoon's formular show good agreement for several different-size specimens.

Flexural Capacity of Encased Composite Beam with Hollow Core PC Slabs (매입형 합성보의 휨 성능 평가 -속 빈 프리캐스트 콘크리트 슬래브와 비대칭 H형강 철골보-)

  • Heo, Byung Wook;Bae, Kyu Woong;Moon, Tae Sup
    • Journal of Korean Society of Steel Construction
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    • v.16 no.5 s.72
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    • pp.587-598
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    • 2004
  • In this study, an experiment was conducted on the Slim Floor system, using a hollow core PC slab, which could reduce the over-all depth of a composite beam. The Slim Floor system is a method used in steel frame multi-story building construction, in which the structural depth of each floor is minimized after incorporating the steel floor beams within the depth of the concrete floor slab. This experimental study focused on the flexural behavior of the partially connected Slim Floor system with asymmetric steel beams encased in hollow core PC slabs. Ten full-scale specimens were constructed and tested in this study, with different steel beam heights, hollow core PC slabs, slab widths, and PC slab bearings. Observations made in line with the experiments indicated that the degree of shear connection without additional shear connection was 0.48-0.98 times more than that of the full shear connection, due to inherent mechanical and chemical bond stress.

Developing a prototype of bi-stretch pants for women in their 20s and 30s with overweight lower bodies (20~30대 하체비만형 여성을 위한 양방향 스트레치 팬츠 원형 개발)

  • Ha, Hee-Jung;Seong, Ok-Jin
    • The Research Journal of the Costume Culture
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    • v.21 no.2
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    • pp.246-260
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    • 2013
  • This research was carried out on women in their 20s and 30s who have overweight lower body. The subjects selected for this study were women a Rohrer index of 1.6 or higher, a waist circumference 78.5cm to 83.5cm, and a lower drop of at least 18cm. The aim is to propose a prototype of bi-stretch pants meeting demands for both functionality and aesthetic appeal. Various clothing patterns ease amount of the waist and hip circumferences and crotch depths and were developed. They had different crotch widths, and center back line angles. The results showed that the best pants patterns were ease 1cm to the total hip circumference. The front hip circumference was H/4-0.5cm, and the back hip circumference was H/4+1cm. The front crotch width was H/20+1cm, the back crotch width was H/10+3cm. No additional ease was given to the total waistline. The front waist circumference was W/4+0.5cm. The back waist circumference was W/4-0.5cm. The knee circumference was set at 44cm, the pant hem width was set at 36cm, and the pant length was set at 100cm-5cm. The findings of this research can be used as basic data for stretch pants that fit the abdomen, hips, and thighs for women in their 20s and 30s with overweight lower body.

Studies on the Micelle Formation of Nonionic Surfactant(1) -1NMR Self-Diffusion and Proton Relaxation of Polyoxyethylene Alkyl Ether- (계면활성제 수용액의 미셀형성(제1보) - Polyoxyethylene Alkyl Ether의 자기확산과 프로톤 이완 -)

  • Choi, Seung-Ok;Jeong, Hwan-Kyeong;Lee, Jin-Hee;Nam, Ki-Dae
    • Applied Chemistry for Engineering
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    • v.9 no.6
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    • pp.822-828
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    • 1998
  • Binary system of water and polyoxyethylene dodecyl ether, $C_{12}H_{25}(OCH_2CH_2)nOH$, have been studied by $^1H$ NMR techniques. For n=5($C_{12}EO_5$) and n=8($C_{12}EO_8$), the self-diffusion coefficients of nonionic surfactants in the isotropic phase($L_1$) have been measured by using pulsed field gradient technique for a range of temperature and concentrations. In addition the line widths of the different proton signals have been monitored, and samples of some liquid crystalline characteristic were also studied. Dramatic Broadening of the methylene signals of the alkyl($C_{12}H_{25}$) chain is observed as the hexagonal liquid crystalline phase is approached in the $C_{12}EO_5-$water system, while only small broadening is observed in the $C_{12}EO_8-$water system. It was shown that there was a growth of $C_{12}EO_5$ micelles to rods with increasing concentrations, while the $C_{12}EO_8-$ micelles at low temperature remain small in the concentration range. The self-diffusion coefficients of the surfactants decrease rapidly with increasing concentration until a minimum is reached after which there is slow increase. The location of the minimum point occurs at lower concentrations the temperature is close to the cloud point, where the system separate into two isotropic phase. In the line width studies, broadening is found at a certain temperature interval when the concentration is increased in the $C_{12}EO_5$ system. The results indicate that the surfactant aggregates grow in size at the cloud point is approached. The aggregates seem to be flexible and probably not to be of a definite shape close to the cloud point. In the $C_{12}EO_8$ system, the micelles are much less affected by an increase in temperature and micellar growth can't be unambiguously established. The methylene signals of the ethylene oxide moieties consistantly show narrower $^1H$ signals, showing that in the aggregates they are less ordered than the chain methylenes. The various changes in aggregate size and shape are correlated with the stability ranges of the isotropic and liquid crystalline phases according to phase diagrams from the literature. Both aggregate size and phase structure are in qualitative agreement with concentration based on the effective shape of the molecules at different temperature and concentration.

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Study on Mathematical Method of Radiation Heat Transfer for Estimating Width of Firebreak in Surface Fire (복사열전달 수치해석을 통한 지표화 방화선 구축 폭 산정에 관한 연구)

  • Kim, Dong-Hyun
    • Journal of the Korean Society of Hazard Mitigation
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    • v.10 no.6
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    • pp.59-64
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    • 2010
  • Building a firebreak against surface forest fire is a typical indirect suppression method that stops spread of flame by removing surface fuel, such as fallen leaves and bushes. In the sense of fire dynamic, building a firebreak is to set a section which will block thermal energy from igniting on virgin fuel. This study suggests and evaluates a calculation method for width of firebreak against surface fire for variant wind and slope conditions by applying the Point Source Model (PSM) to fallen leaves of Pinus densiflora. Width of firebreak was measured based on the distance the threshold radiant heat igniting Pinus densiflora fallen leaves at the heat flux of $4.9\;kW/m^2$ reaches. As a result, at the wind velocity of 0~5 m/s and on the slope of $0{\sim}50^{\circ}$, the appropriate width of a firebreak was 0.35~0.65 m for the mean flame height and 0.75~1.05 m for the maximum flame height. Accordingly, considering the factor of safety, the most appropriate width of a firebreak is 1.05 m based on the maximum flame height. Additional comparative analyses through experiments and field surveys are deemed necessary to determine appropriate widths of firebreak for different types of surface fuel.