• Korean Journal of Radiology
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• 제22권12호
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• pp.1964-1973
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• 2021

Objective: To investigate the diagnostic performance of CT fractional flow reserve (CT-FFR) for myocardial bridging-related ischemia using dynamic CT myocardial perfusion imaging (CT-MPI) as a reference standard. Materials and Methods: Dynamic CT-MPI and coronary CT angiography (CCTA) data obtained from 498 symptomatic patients were retrospectively reviewed. Seventy-five patients (mean age ± standard deviation, 62.7 ± 13.2 years; 48 males) who showed myocardial bridging in the left anterior descending artery without concomitant obstructive stenosis on the imaging were included. The change in CT-FFR across myocardial bridging (ΔCT-FFR, defined as the difference in CT-FFR values between the proximal and distal ends of the myocardial bridging) in different cardiac phases, as well as other anatomical parameters, were measured to evaluate their performance for diagnosing myocardial bridging-related myocardial ischemia using dynamic CT-MPI as the reference standard (myocardial blood flow < 100 mL/100 mL/min or myocardial blood flow ratio ≤ 0.8). Results: ΔCT-FFR_systolic (ΔCT-FFR calculated in the best systolic phase) was higher in patients with vs. without myocardial bridging-related myocardial ischemia (median [interquartile range], 0.12 [0.08-0.17] vs. 0.04 [0.01-0.07], p < 0.001), while CT-FFR_systolic (CT-FFR distal to the myocardial bridging calculated in the best systolic phase) was lower (0.85 [0.81-0.89] vs. 0.91 [0.88-0.96], p = 0.043). In contrast, ΔCT-FFR_diastolic (ΔCT-FFR calculated in the best diastolic phase) and CT-FFR_diastolic (CT-FFR distal to the myocardial bridging calculated in the best diastolic phase) did not differ significantly. Receiver operating characteristic curve analysis showed that ΔCT-FFR_systolic had largest area under the curve (0.822; 95% confidence interval, 0.717-0.901) for identifying myocardial bridging-related ischemia. ΔCT-FFR_systolic had the highest sensitivity (91.7%) and negative predictive value (NPV) (97.8%). ΔCT-FFR_diastolic had the highest specificity (85.7%) for diagnosing myocardial bridging-related ischemia. The positive predictive values of all CT-related parameters were low. Conclusion: ΔCT-FFR_systolic reliably excluded myocardial bridging-related ischemia with high sensitivity and NPV. Myocardial bridging showing positive CT-FFR results requires further evaluation.

• Clinical and Experimental Pediatrics
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• 제53권1호
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• pp.72-79
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• 2010

목 적 : 고혈압에서 이완기 기능 이상은 수축기 기능 장애가 나타나기 전에 질환 경과에 일찍 발견되고 흔하게 관찰된다. 이완기 심기능을 평가하기에는 TDI가 고식적 심초음파보다 더 우수한 것으로 알려져 있다. 그러나 소아 및 청소년에서의 연구는 많지 않은 실정이다. 청소년 고혈압에서 심실 기능 이상을 발견하는데 있어서 SRI의 유용성을 알아보고자 본 연구를 실시하였다. 방 법: 수축기 혈압이 140 mmHg 이상이거나 이완기 혈압이 90 mmHg이상인 고혈압을 가진 16-17세 사이의 38명의 청소년을 대상군으로 하였고, 같은 연령의 정상 혈압을 가진 청소년 19명을 대조군으로 하였다. M-mode 심초음파로 심실 중격 두께, 좌심실 후벽 두께를 측정하였고, 이면성 심초음파로 ejection fraction (EF), myocardial performance index (MPI)를 측정하였다. TDI를 이용하여 심근 수축기 심근속도, E 심근속도, A 심근속도를 측정하였고, SRI를 이용하여 strain과 strain rate을 측정하였다. 결 과: M-mode 심초음파 소견상 심실벽 두께, 좌심실 후벽 두께가 고혈압군에서 유의하게 증가하였다. EF, MPI와 modified MPI는 두군간에 유의한 차이가 없었다. 고식적 심초음파 검사결과 고혈압군에서 A 혈류속도가 유의하게 증가되었고, TDI 검사상 A 심근 속도는 고혈압군에서 유의하게 증가하였고 E/A 심근속도비는 유의하게 감소되었다. SRI에 의한 E strain rate은 고혈압군에서 기저, 중간 부위, 심첨부에서 유의하게 감소되었고, strain은 중격에서 고혈압군은 $19.15{\pm}8.65%$, 정상군은 $22.63{\pm}5.55%$으로 고혈압군에서 유의하게 감소하였다(P<0.05). 결 론 : 고식적 초음파로는 좌심실 이완기 기능 이상만 관찰되었으나 SRI로 좌심실 이완 기능 외에 수축 기능이 유의하게 감소됨을 알 수 있었다. SRI를 이용하여 심실 기능의 이상을 조기에 발견할 수 있었다. 앞으로 더 많은 고혈압 청소년을 대상으로 한 연구가 필요할 것으로 생각한다.

• 대한방사선협회지
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• 제29권1호
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• pp.170-170
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• 2003

• 대한예방의학회:학술대회논문집
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• 대한예방의학회 1998년도 제50차 추계 학술대회 연제집
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• pp.279-280
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• 1998

• Journal of Cardiovascular Imaging
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• 제26권4호
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• pp.226-228
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• 2018

• Journal of the Korean Data and Information Science Society
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• 제26권4호
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• pp.1007-1015
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• 2015

The purpose of this study was to explore the prevalence of hypertension in Haiti and to describe regional characteristics, and thus to speculate Haitian specific regional risk factors. This is a descriptive and comparative study. Subjects were 145 male/female Haitians, who aged between 30 and 59 and have lived in rural areas, had their hypertension indicators being screened. Data were analyzed with descriptive statistics, t-test and ANOVA. More than four fifth of the subjects (82.8%) showed pre-hypertensive or moderate to severe hypertensive condition. 65.5% of the total had abnormal pulse pressure ($PP{\geq}50$) and 13.8% of the sample showed tachycardia (Heart $Rate{\geq}100$). Female Haitian tended to have higher diastolic blood pressure and faster heart rate than male Haitian. The residents who lived in Part 5-1 area with less accessibility to drinking water tended to have higher systolic and diastolic pressure. Hydration status of Haitians was highly considered as an affecting factor on the distribution of hypertension as evidenced by different level of accessibility to drinking water.

• The Journal of Korean Physical Therapy
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• 제15권2호
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• pp.111-122
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• 2003

The purpose of this study was to investigate the influence on sympathetic nerve system of interferential current therapy(ICT). The subjects were consisted of 20 senile patients, 10 males and 10 females with an average age of 71 years old. And systolic and diastolic blood pressure, temperature, heart rate, and respiratory were tested. The results were as follows: 1) Systolic and diastolic blood pressure were observed a statistical significance between before and during stimulation(p < .05). 2) Temperature was observed a statistical significance between before and during, and before and after 10 minutes stimulation(p < .05). 3) Heart rate and respiratory were not statistical significance(p > .05). These results are imply that electrical stimulation is directly or indirectly influence on sympathetic nerve system.

• Journal of Chest Surgery
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• 제23권6호
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• pp.1067-1073
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• 1990

To clarify the changes of left ventricular function under normothermia, the time interval between the onset of ischemia and the beginning of contracture of left ventricle[TIC] were recorded in newborn piglet. Myocardial performance was assessed using intraventricular balloon to determine compliance and systolic function after 5 to 10 minutes interval per-fusing normothermic substrate free Krebs solution as a perfusate. The time to onset TIC was 29.5\ulcorner1.7 minutes and peak ischemic contracture was 46.7\ulcorner4.0 minutes[p<0.01]. In myocardial performance, systolic function of left ventricle[defined as cardiac contractility] was kept until 25 minutes of perfusion, but was decreased abruptly after 30 minutes of perfusion[p<0.0018] and diastolic function of left ventricle[defined as diastolic compliance] was kept until 15 minutes of perfusion, but was decreased after 20 minutes of perfusion [p=0.00\ulcorner9]. This study demonstrated maximal time of the tolerance to normothermic global ischemia and functional changes of left ventricle using Krebs perfusate under the same condition.

• 한국환경과학회지
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• 제25권9호
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• pp.1213-1222
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• 2016

Given the growing attention to nature and health in modern society, this study considered the role of a waterscape facility as a key element in a landscape's influence on users' physiological and psychological responses. The subjects were 28 university students, and the collected data included systolic and diastolic blood pressure, salivary amylase concentration, semantic differential (SD) scales, and profile of mood states (POMS). As compared to a space without any waterscape element (Type G), relaxation in a space with a waterscape element (Type W) was found to significantly reduce of systolic and diastolic blood pressure and salivary amylase concentration. The SD scale and POMS findings showed that Type W evoked active, bright, dynamic, free, vital, interesting, and cheerful images and improved mood states by enhancing vigor while inhibiting depressive feelings. These findings indicate waterscape facilities can improves users' mood states and may enhance their health.

• 대한의용생체공학회:학술대회논문집
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• 대한의용생체공학회 1997년도 추계학술대회
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• pp.415-419
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• 1997

The left ventricular relaxation rate is used as a golden standard which describes the left ventricular diastolic unction. So far, to get the rate of relaxation one should calculate the data after full recording, that is, off-line method. Therefore one cannot get the rate of relaxation in real-time while changing loading condition or infusing drug. But real time monitoring of the relaxation rate is necessary while changing loading condition or infusing drug to control the mechanics of heart and to get more information. We propose a new criterion to get the left ventricular relaxation rate and a real time algorithm. By comparison, it was turned out that our criterion outperforms others criterion.