• The Korean Journal of Cytopathology
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• v.9 no.2
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• pp.147-153
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• 1998

We have investigated the cervicovaginal smears in order to define the cytologic features of uterine adenocarcinomas. Total 22 cases were reviewed(12 cases from the Sanggye Paik hospital, Inje university and 10 cases from the Korea Cancer Center Hospital) from January 1992 to December 1997. Five cases were endometrial adenocarcinomas and the remaining 17 cases were cervical adenocarcinomas. Seventeen cases of cervical adenocarcinomas were divided into endometrioid(6 cases), endocervical(7 cases), mixed endometrioid and endocervical(1 case), papillary (2 cases), and adenosquamous(1 case) carcinomas. The background of endocervical adenocarcinoma was hemorrhagic or inflammatory. The tumor diathesis was less prominent than that of the squamous cell carcinoma. The prominent features of the endocervical type adenocarcinomas were large and loose clusters, large intracytoplasmic vacuoles, and prominent overlapping and peripheral palisading of nuclei. In contrast, the endometrioid adenocarcinomas showed small and compact clusters, and small intracytoplasmic vacuoles. The detection rate of endometrial adenocarcinoma was lower than that of the endocervical adenocarcinoma.

• Journal of Mechanical Science and Technology
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• v.18 no.9
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• pp.1537-1548
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• 2004

This paper presents a novel diagnostic technique for monitoring the system conditions and detecting failure modes and precursors based on wavelet-packet analysis of external noise/vibration measurements. The capability is based on extracting relevant features of noise/vibration data that best discriminate systems with different noise/vibration signatures by analyzing external measurements of noise/vibration in the time-frequency domain. By virtue of their localized nature both in time and frequency, the identified features help to reveal faults at the level of components in a mechanical system in addition to the existence of certain faults. A prima-facie case is made via application of the proposed approach to fault detection in scroll and rotary compressors, although the methods and algorithms are very general in nature. The proposed technique has successfully identified the existence of specific faults in the scroll and rotary compressors. In addition, its capability of tracking the severity of specific faults in the rotary compressors indicates that the technique has a potential to be used as a prognostic tool.

• The Journal of the Society of Korean Medicine Diagnostics
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• v.12 no.2
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• pp.8-17
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• 2008

Objectives: For the traditional pulse diagnosis in Oriental Medicine, not only the pulse shape in time domain, but the width, length and depth of arterial pulse also should be measured. However, conventional pulse diagnostic systems have failed to measure the spatial parameters of the arterial pulse e.g. effective length of arterial pulse in the wrist. In fact, there are many ways to measure that kind of spatial features in arterial pulsation, but among them, the method using image sensor provides relatively cheap and simple way, therefore I tested feasibility of measuring 2-dimensional pressure distribution by imaging devices. Methods: Using widely used PC cameras and dotted balloons, the subtle oscillation of skin over the radial artery was recorded continuously, and then the displacement of every dot was calculated. Consequently, the time course of that displacements shows arterial pulse wave. Results: By the proposed method I could get pressure distribution map with 30Hz sampling rate, 21steps quantization resolution, and approximately 1mm spatial resolution. With reduced quantization resolution, $3cm{\times}4cm$ view angle could be achieved. Conclusion: Although this method has some limitations, it would be useful method for detecting 2-dimensional features of arterial pulse, and accordingly, this method provides a novel way to detect 'narrow pulse', 'wide pulse', 'long pulse', 'short pulse', and their derivatives.

• Journal of Genetic Medicine
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• v.10 no.2
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• pp.88-93
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• 2013

Alexander disease (ALXD) is a rare demyelinating disease of the white matter of the brain that is caused by a mutation in the glial fibrillary acidic protein (GFAP) gene. The overexpression of GFAP in astrocytes induces a failure in the developmental growth of the myelin sheath. The neurodegenerative destruction of the myelin sheath of the white matter is accompanied by an accumulation of abnormal deposits of Rosenthal fibers in astrocytes, which is the hallmark of ALXD. The disease can be divided into four groups based on the onset age of the patients: neonatal, infantile, juvenile, or adult. Early-onset disease is more severe, progresses rapidly, and results in a shorter life span than late-onset cases. Magnetic resonance imaging and genetic tests are mostly used for diagnostic purposes. Pathological tests of brain tissue for Rosenthal fibers are definitive diagnostic methods. Therapeutic strategies are being investigated. Ceftriaxone, which is an enhancer of glial glutamate transporter (GLT-1) expression, is currently in clinical trials for the treatment of patients with ALXD. To date, there are no clinically available treatments. The cause, pathology, pathophysiology, inheritance, clinical features, diagnosis, and treatment of ALXD will be reviewed comprehensively.

• Journal of Veterinary Clinics
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• v.32 no.1
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• pp.49-55
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• 2015

This study was retrospectively investigated the clinical features, diagnostic imaging, treatment, and prognosis of foreign bodies according to alimentary site and type of foreign body, in 143 dogs. Among 28 breeds, Maltese, Shih Tzu, and terriers including the Yorkshire terrier were presented with high prevalence. Bone was the most commonly identified (33%) foreign body regardless of alimentary site. Approximately 76% of foreign bodies were in the stomach and small intestine. All esophageal foreign bodies were diagnosed on survey radiography, with the most common location being the caudal thoracic esophageal segment. Further diagnostic examinations including ultrasonography or contrast studies were additionally performed to detect radiolucent foreign bodies and perforation or leakage in the stomach and intestine. However, most seeds could be identified based on the characteristic features such as hyperdense thin double lines and inner gas on survey radiography. In conclusion, complications such as peritonitis and intestinal perforation were mainly observed in cases with seeds and linear foreign bodies. Especially, fabric foreign bodies could be induce peritonitis and re-perforation with high prevalence after surgical correction.

• Journal of Species Research
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• v.10 no.4
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• pp.364-386
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• 2021

Six species of the family Kelleriidae, including four new species, are recorded from tropical waters of the Asia-Pacific, two of them from Phuket Island, Thailand, one each from Bohol Island, Philippines and Phu Quoc Island, Vietnam, and two from Kosrae Island, Micronesia. A new genus Kelleriella is proposed to accomodate one of these new species (Kelleriella quadridens n. sp.). There are three diagnostic features of the new genus: the terminal segment of antenna is armed with one strong claw and six setae, the armature of the maxilliped endopod is reduced, and the third exopodal segment of leg 4 is armed with four spines and five setae. The other three new species are Kelleria latipes n. sp., Kelleria phuketensis n. sp., and Kelleria robusta n. sp. As diagnostic features of these new species, their caudal rami are about 2.5, 3.2, and 1.72 times longer than wide, respectively, the exopod of leg 5 of them is smooth, without any process, about 1.9, 3.7, and 2.9 times longer than wide, respectively, and armed with one spine plus one seta in Kelleria latipes and Kelleria phuketensis or with 2 setae in Kelleria robusta. Additionally, Kelleria javaensis Mulyadi, 2009 is synonymized with Kelleria regalis Gurney, 1927 and Kelleria grandisetiger Kim, 2006 is synonymized with Kelleria andamanensis Sewell, 1949, and both species are redescribed.

• Journal of the Korean Society of Radiology
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• v.81 no.2
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• pp.379-394
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• 2020

Purpose To design a scoring system to predict malignancy of additional MRI-detected lesions in breast cancer patients. Materials and Methods Eighty-six lesions (64 benign and 22 malignant) detected on preoperative MRI of 68 breast cancer patients were retrospectively included. The clinico-radiologic features were correlated with the histopathologic results using the Student's t-test, Fisher's exact test, and logistic regression analysis. The scoring system was designed based on the significant predictive features of malignancy, and its diagnostic performance was compared with that of the Breast Imaging-Reporting and Data System (BI-RADS) category. Results Lesion size ≥ 8 mm (p < 0.001), location in the same quadrant as the primary cancer (p = 0.005), delayed plateau kinetics (p = 0.010), T2 isointense (p = 0.034) and hypointense (p = 0.024) signals, and irregular mass shape (p = 0.028) were associated with malignancy. In comparison with the BI-RADS category, the scoring system based on these features with suspicious non-mass internal enhancement increased the diagnostic performance (area under the receiver operating characteristic curve: 0.918 vs. 0.727) and detected three false-negative cases. With this scoring system, 22 second-look ultrasound examinations (22/66, 33.3%) could have been avoided. Conclusion The scoring system based on the lesion size, location relative to the primary cancer, delayed kinetic features, T2 signal intensity, mass shape, and non-mass internal enhancement can provide a more accurate approach to evaluate MRI-detected lesions in breast cancer patients.

• The Korean Journal of Cytopathology
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• v.8 no.1
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• pp.87-92
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• 1997

Reports on the cytologic or histopathologic findings of inflammatory pseudotumors are relatively infrequent and most of them have dealt with those involving the lung, liver, genitourinary tract, alimentary tract, spleen, mediastinum, retroperitoneum, etc. Moreover there have not been any cytologic studios of those involving lymph nodes. We present fine needle aspiration cytologic features of inflammatory pseudotumor occurring in a lymph node in a 64 year-old man. The aspirate consisted of proliferating spindle cells and admixed histiocytes, fibroblasts, lymphocytes, and plasma cells. Histiocytes were present either singly or in loosely cohesive small clusters. A few multinucleated giant cells were present as well. However, tuberculosis could be excluded by the absence of typical granuloma, caseation necrosis, or characteristic mixed spindle and inflammatory cell components. Other benign and malignant lymphadenopathies could also be differentiated based on cytologic findings.

• The Journal of the Society of Korean Medicine Diagnostics
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• v.22 no.1
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• pp.19-31
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• 2018

For the purpose of the basic educated-establishment on the diagnostic methods of "facial color and shape which reflect human's spiritual essence and personality", we study on the diagnostic value and application of the human face. The study's domain is divided the form and color of human face. And the form and color of human face is respectively observed the diagnostic value and contents. The form of human face reflect plenty the information of the mankind, and the observation of the face is applied to the "Physiognomie" refering to the external features of humans. Therefore the diagnosis on the form of human face is the primary factor in the grouping of five-element human, the discrimination of the Sasang constitution, and the classification of Hyunsang type. The color of human face reflect the physical information of internal organs and the pathological change of disease, therefore we examine the region, character and grade of disease by the inspection of complexion including the changes of color and luster of the facial skin. The inspection on the color is also the primary factor in the grouping of five-element human, the classification of Hyunsang and the differentiation of syndromes. The value of the inspection of complexion including the changes of color and form of the face is widely known. In the future, we think, we need to study more about the theory of the diagnostic value and application of the human face.

• Korean Journal of Radiology
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• v.2 no.4
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• pp.183-191
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• 2001

Objective: To document the signal characteristics of intracerebral hemorrhage (ICH) at evolving stages on diffusion-weighted images (DWI) by comparison with conventional MR images. Materials and Methods: In our retrospective study, 38 patients with ICH underwent a set of imaging sequences that included DWI, T1-and T2-weighted imaging, and fluid-attenuated inversion recovery (FLAIR). In 33 and 10 patients, respectively, conventional and echo-planar T2^* gradient-echo images were also obtained. According to the time interval between symptom onset and initial MRI, five stages were categorized: hyperacute (n=6); acute (n=7); early subacute (n=7); late subacute (n=10); and chronic (n=8). We investigated the signal intensity and apparent diffusion coefficient (ADC) of ICH and compared the signal intensities of hematomas at DWI and on conventional MR images. Results: DWI showed that hematomas were hyperintense at the hyperacute and late subacute stages, and hypointense at the acute, early subacute and chronic stages. Invariably, focal hypointensity was observed within a hyperacute hematoma. At the hyperacute, acute and early subacute stages, hyperintense rims that corresponded with edema surrounding the hematoma were present. The mean ADC ratio was 0.73 at the hyperacute stage, 0.72 at the acute stage, 0.70 at the early subacute stage, 0.72 at the late subacute stage, and 2.56 at the chronic stage. Conclusion: DWI showed that the signal intensity of an ICH may be related to both its ADC value and the magnetic susceptibility effect. In patients with acute stroke, an understanding of the characteristic features of ICH seen at DWI can be helpful in both the characterization of intracranial hemorrhagic lesions and the differentiation of hemorrhage from ischemia.