• Advances in pediatric surgery
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• 제8권1호
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• pp.48-53
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• 2002

Diagnosing Hirschprungs disease (HD) is a clinical challenge to pediatric surgeons. The cardinal symptoms are failure of passage of meconium within first 24 hours of life, abdominal distension, and vomiting. The severity of these symptoms and the degree of consitpation vary considerably between patients. HD is suspected on the basis of history and clinical findings and the diagnosis is established by radiological examination, anorectal manometry, and histochemical analysis of biopsy specimens. In this review, the advantages and pitfalls of each diagnostic modality are discussed. And a diagnostic approach utilizing these diagnostic modalities in children with suspicious HD is presented.

• Clinical and Experimental Pediatrics
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• 제49권2호
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• pp.117-128
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• 2006

Non-traumatic acute abdominal pain in children presents a diagnostic dilemma. Numerous disorders can cause abdominal pain. Although many etiologies are benign, some require a rapid diagnosis and treatment in order to minimize morbidity. This review concentrates on the clinical office evaluation of acute abdominal pain in infants and children and details the clinical guideline for the diagnostic approach to imaging and the salient clinical features of some of the conditions. The clinical outcomes of children presenting with acute abdominal pain and the risk factors of the high risk underlying diseases would be provided for the diagnostic algorithm.

• 식물분류학회지
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• 제31권4호
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• pp.321-341
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• 2001

벼속(Oryza) 잎의 식물규소체에 대한 분류학적 연구의 일환으로 표징형질을 정립하고 검색표를 작성하고자 광학현미경과 주사전자현미경을 사용하였다. 벼의 잎에서 가장 다양한 형태의 규소체를 형성했던 기공장치규소체, 장세포규소체 그리고 단세포규소체 등을 대상으로 엽신 배축면의 동일한 위치에 형성된 종류를 집중적으로 조사하였다. 이들 규소체의 특징은 속내 분류체계의 설정과 종을 동정하는데 유용하게 사용될 수 있었다. 기공장치규소체는 공변세포와 부세포 상의 유두상돌기 유래 규소체의 발달 유무와 배열 양상의 특징이 다양하게 나타났고, 이들의 특징은 절 및 계열 수준에서 기존 분류체계와 일치하였다. 장세포규소체는 표면에 유두상돌기의 발달 유무, 배열양상 및 형태 등에 따라 다양한 형태가 확인되었다. 그러나 확인된 특징이 본 속내 기존 분류체계와 일치하기보다는, 종의 동정에 유용한 것으로 생각되었다. 단세포규소체는 모두 형판규소체로 십자형, 안장형, 이완형 그리고 3완형 등이 확인되었으며, 이들의 특징은 절 및 계열 수준에서 계통학적으로 의의가 있었다. 또한 단세포규소체가 맥상표피역에 밴드를 형성하는 종류와 밴드를 형성하지 않는 종류, 유관속 종류에 따른 맥상표피역 규소괴의 밴드 수 그리고 맥간표피역에 안장형 규소체의 발달 여부 등에 따라 다양한 종류가 확인되었으나, 이들의 특징이 속내 분류체계와 일치하지 않는 것으로 나타났다. 조사된 기공장치규소체, 장세포규소체 그리고 단세포규소체 등의 특징에 따라 각각 검색표를 작성하였고, 각 형질의 특징과 속내 분류계급과 비교하여 계통학적 의의를 논의하였다.

• Investigative Magnetic Resonance Imaging
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• 제25권4호
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• pp.313-322
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• 2021

Purpose: To find diagnostic image features, to compare diagnostic performance of multiphase CT versus gadoxetic acid disodium-enhanced MRI (GAD-MRI), and to evaluate the impact of analyzing Liver Imaging Reporting and Data System (LI-RADS) imaging features, for distinguishing combined hepatocellular-cholangiocarcinoma (CHC) from hepatocellular carcinoma (HCC). Materials and Methods: Ninety-six patients with pathologically proven CHC (n = 48) or HCC (n = 48), diagnosed June 2008 to May 2018 were retrospectively analyzed in random order by three radiologists with different experience levels. In the first analysis, the readers independently determined the probability of CHC based on their own knowledge and experiences. In the second analysis, they evaluated imaging features defined in LI-RADS 2018. Area under the curve (AUC) values for CHC diagnosis were compared between CT and MRI, and between the first and second analyses. Interobserver agreement was assessed using Cohen's weighted κ values. Results: Targetoid LR-M image features showed better specificities and positive predictive values (PPV) than the others. Among them, rim arterial phase hyperenhancement had the highest specificity and PPV. Average sensitivity, specificity, and AUC values were higher for MRI than for CT in both the first (P = 0.008, 0.005, 0.002, respectively) and second (P = 0.017, 0.026, 0.036) analyses. Interobserver agreements were higher for MRI in both analyses (κ = 0.307 for CT, κ = 0.332 for MRI in the first analysis; κ = 0.467 for CT, κ = 0.531 for MRI in the second analysis), with greater agreement in the second analysis for both CT (P = 0.001) and MRI (P < 0.001). Conclusion: Rim arterial phase hyperenhancement on GAD-MRI can be a good indicator suggesting CHC more than HCC. GAD-MRI may provide greater accuracy than CT for distinguishing CHC from HCC. Interobserver agreement can be improved for both CT and MRI by analyzing LI-RADS imaging features.

• 사상체질의학회지
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• 제29권1호
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• pp.29-39
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• 2017

Objectives Facial features can be utilized as an indicator of Korean medical diagnosis. They are often measured by using the diagnostic device for an objective diagnosis. Accordingly, it is necessary to verify the reliability of the features which are obtained from the device for the accurate diagnosis. In this study, we attempt to evaluate the repeatability of facial feature variables using the Sasang Constitutional Analysis Tool(SCAT) for the Sasang Constitutional face diagnosis. Methods Facial pictures of two subjects were taken 24 times respectively for two days according to a standard guideline. In order to evaluate the repeatability, the coefficient of variation was calculated for the facial features extracted from frontal and profile images. Results The coefficient of variation was less than 10% in most of the facial features except the upper lip, trichion, and chins related features. Conclusions It was confirmed that the coefficient of variation was small in most of the features which enables the objective and reliable analysis of face. However, some features showed the low reliability because the location of facial landmarks related to them is ambiguous. In order to solve the problem, a clear basis for the location discussion is required.

• The Korean Journal of Pain
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• 제32권2호
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• pp.120-128
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• 2019

Background: We aimed to explore the American College of Rheumatology (ACR) 1990 and 2011 fibromyalgia (FM) classification criteria's items and the components of Fibromyalgia Impact Questionnaire (FIQ) to identify features best discriminating FM features. Finally, we developed a combined FM diagnostic (C-FM) model using the FM's key features. Methods: The means and frequency on tender points (TPs), ACR 2011 components and FIQ items were calculated in the FM and non-FM (osteoarthritis [OA] and non-OA) patients. Then, two-step multiple logistic regression analysis was performed to order these variables according to their maximal statistical contribution in predicting group membership. Partial correlations assessed their unique contribution, and two-group discriminant analysis provided a classification table. Using receiver operator characteristic analyses, we determined the sensitivity and specificity of the final model. Results: A total of 172 patients with FM, 75 with OA and 21 with periarthritis or regional pain syndromes were enrolled. Two steps multiple logistic regression analysis identified 8 key features of FM which accounted for 64.8% of variance associated with FM group membership: lateral epicondyle TP with variance percentages (36.9%), neck pain (14.5%), fatigue (4.7%), insomnia (3%), upper back pain (2.2%), shoulder pain (1.5%), gluteal TP (1.2%), and FIQ fatigue (0.9%). The C-FM model demonstrated a 91.4% correct classification rate, 91.9% for sensitivity and 91.7% for specificity. Conclusions: The C-FM model can accurately detect FM patients among other pain disorders. Re-inclusion of TPs along with saving of FM main symptoms in the C-FM model is a unique feature of this model.

• 한국동물위생학회지
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• 제41권2호
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• pp.91-95
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• 2018

Polioencephalomalacia (PEM) is a neurologic disease of ruminants diagnosed by pathological approach. There is very little information available to understand bovine PEM in Korea. In this study, we investigated the diagnostic rate and pathological features of PEM in 334 necropsied cases of cattle submitted to the Animal and Plant Quarantine Agency in Korea from 2015~2017. PEM was diagnosed only in 13 (3.9%) Hanwoo, the Korean native cattle, and sporadically occurred in our country. The disease was the most diagnosed in fall season, and the age of the cows ranged from 1 month to 3 year. In all PEM cases, softening, and yellow discoloration of the gray matter in the cerebrum and fluorescence at the sites using ultraviolet illumination were grossly observed. Microscopically abundance of glial cells with vacuolar large cytoplasm and neuronal necrosis were commonly observed. This study suggests that future studies are necessary to identify the cause and pathogenesis for the control of PEM in our country.

• 대한치과의사협회지
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• 제57권11호
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• pp.690-699
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• 2019

Ultrasound sonography(US) is used to evaluate various diseases of maxillofacial region including salivary glands, soft tissue and jaw lesions because of easy accessibility and no hazard of ionizing radiation. Also, US can offer dynamic study showing real-time images during diagnostic or surgical procedure. US images provide accurate information about the internal features of lesions on the jaw prior to surgical treatment. Doppler images are used to visualize the vascular distribution of the lesions and to provide additional information to enhance diagnostic value. Nevertheless, the clinical application of US imaging is limited in the dental field. This is due to the lack of knowledge about the US image and the image characteristics of the anatomical structures. It is necessary to evaluate the diagnostic value of US and evaluate its usefulness by looking at clinical cases using US images. Therefore, US imaging may be recommended as an assistant image in evaluating jaw lesions. US images provided accurate information about the internal structure of lesions on the jaw prior to surgical treatment, and diagnostic value was enhanced by visualizing the vascular distribution of the lesion using doppler imaging.

• 가정∙방문간호학회지
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• 제24권2호
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• pp.151-159
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• 2017

Purpose: The purpose of this study was to identify nursing demands according to general characteristics and diseases of inpatients to whom comprehensive payment systems apply. Methods: This study was designed as a retrospective research study using the electronic medical records of Hospital Information Systems (HIS). Participants were 836 subjects who received seven Diagnostic-Related Group diagnoses among inpatients of one tertiary hospital from January 1, 2015 to June 30, 2015. Data were analyzed using SPSS 23.0. Results: Nursing demand among inpatients'seven Diagnostic-Related Group diagnoses was relatively higher for appendectomy, cataract surgery, and hysterectomy, while there was a significant difference depending on the age, duration of admission, admission path, hospital entry method and Diagnostic-Related Group. Conclusion: The results can be utilized as basic data on accurate nursing demands that reflect various features of patients.

• Tuberculosis and Respiratory Diseases
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• 제87권1호
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• pp.91-99
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• 2024

Background: Tuberculous pleural effusion (TPE) and parapneumonic effusion (PPE) are often difficult to differentiate owing to the overlapping clinical features. Observational studies demonstrate that the ratio of lactate dehydrogenase to adenosine deaminase (LDH/ADA) is lower in TPE compared to PPE, but integrated analysis is warranted. Methods: We conducted a systematic review to evaluate the diagnostic accuracy of the LDH/ADA ratio in differentiating TPE and PPE. We explored the PubMed and Scopus databases for studies evaluating the LDH/ADA ratio in differentiating TPE and PPE. Results: From a yield of 110 studies, five were included for systematic review. The cutoff value for the LDH/ADA ratio in TPE ranged from <14.2 to <25. The studies demonstrated high heterogeneity, precluding meta-analysis. Quality Assessment of Diagnostic Accuracy Studies Tool 2 assessment revealed a high risk of bias in terms of patient selection and index test. Conclusion: LDH/ADA ratio is a potentially useful parameter to differentiate between TPE and PPE. Based on the limited data, we recommend an LDH/ADA ratio cutoff value of <15 in differentiating TPE and PPE. However, more rigorous studies are needed to further validate this recommendation.