• Asian Pacific Journal of Cancer Prevention
• /
• 제17권7호
• /
• pp.3651-3658
• /
• 2016

Computer-aided diagnosis of breast cancer is an important medical approach. In this research paper, we focus on combining two major methodologies, namely fuzzy base systems and the evolutionary genetic algorithms and on applying them to the Saudi Arabian breast cancer diagnosis database, to aid physicians in obtaining an early-computerized diagnosis and hence prevent the development of cancer through identification and removal or treatment of premalignant abnormalities; early detection can also improve survival and decrease mortality by detecting cancer at an early stage when treatment is more effective. Our hybrid algorithm, the genetic-fuzzy algorithm, has produced optimized systems that attain high classification performance, with simple and readily interpreted rules and with a good degree of confidence.

• Journal of mucopolysaccharidosis and rare diseases
• /
• 제2권1호
• /
• pp.1-4
• /
• 2016

Mucolipidosis type II (MLII; MIM#252500) and type III alpha/beta (MLIIIA; MIM#252600) very rare lysosomal storage disease cause by reduced enzyme activity of GlcNAc-1-phosphotransferase. ML II is caused by a total or near total loss of GlcNAc-1-phosphotransferase activity whether enzymatic activity in patient with ML IIIA is reduced. While ML II and ML III share similar clinical features, including skeletal abnormalities, ML II is the more severe in terms of phenotype. ML III is a much milder disorder, being characterized by latter onset of clinical symptoms and slower progressive course. GlcNAc-1-phosphotransferase is encoded by two genes, GNPTAB and GNPTG, mutations in GNPTAB give rise to ML II or ML IIIA. To date, more than 100 different GNPTAB mutations have been reported, causing either ML II or ML IIIA. Despite development of new diagnostic approach and understanding of disease mechanism, there is no specific treatment available for patients with ML II and ML IIIA yet, only supportive and symptomatic treatment is indicated.

• International Journal of Fuzzy Logic and Intelligent Systems
• /
• 제4권2호
• /
• pp.211-216
• /
• 2004

Fuzzy neural networks have been successfully applied to analyze/generate predictive rules for medical or diagnostic data. However, most approaches proposed so far have not considered the weights for the membership functions much. This paper presents a neural network with weighted fuzzy membership functions. In our approach, the membership functions can capture the concentrated and essential information that affects the classification of the input patterns. To verify the performance of the proposed model, well-known Iris data set is performed. According to the results, the weighted membership functions enhance the prediction accuracy. The architecture of the proposed neural network with weighted fuzzy membership functions and the details of experimental results for the data set is discussed in this paper.

• 제어로봇시스템학회:학술대회논문집
• /
• 제어로봇시스템학회 2000년도 제15차 학술회의논문집
• /
• pp.130-130
• /
• 2000

This paper presents a robust fault diagnosis and fault tolerant control lot the actuator and sensor faults in the closed-loop systems affected by unknown inputs or disturbances. The fault diagnostic scheme is based on the residual set generation by using robust Parity space approach. Residual set is evaluated through the threshold test and then fault is isolated according to the decision logic table. Once the fault diagnosis module indicates which actuator or sensor is faulty, the fault magnitude is estimated by using the disturbance-decoupled optimal state estimation and a new additive control law is added to the nominal one to override the fault effect on the system. Simulation results show that the method has definite fault diagnosis and fault tolerant control ability against actuator and sensor faults.

• 대한수의학회지
• /
• 제47권4호
• /
• pp.461-467
• /
• 2007

A 6-year-old female Maltese dog (body weight 2.0 kg) was referred to the Veterinary Teaching Hospital, Kangwon National University with primary complaints including exercise intolerance and heart murmur. Based on clinical and diagnostic findings including grade V/VI left basal continuous murmur, bounding femoral pulsation, left ventricular enlargement pattern in electrocardiogram, cardiomegaly with aortic bulging on the thoracic radiography, and shunt flow between aorta and pulmonary artery on the echocardiography, the dog was diagnosed as the left-to-right patent ductus arteriosus. The patent ductus arteriosus was successfully treated by lodging a single embolization coil with transjugular approach.

• 응용통계연구
• /
• 제7권2호
• /
• pp.213-224
• /
• 1994

두개의 공분산 행렬의 동질성을 검정하는데 있어서, influence curve 방법을 이용하여 outlier를 찾는데 유용한 진단법을 제시한다. 이러한 진단법은 두개 이상의 공분산 행렬의 경우에 쉽게 일반화된다. 경험적 분포함수에 입각한 진단법의 sample version을 고려하며, 이것은 Wilks가 제안한 한개의 outlier를 찾는데 필요한 통계량과 두개의 모집단의 경우로 일반화된 Wilks 통계량을 포함한다.

• 동의생리병리학회지
• /
• 제19권3호
• /
• pp.830-833
• /
• 2005

Intracranial lipomas are rare lesions, which are believed to be congenital malformations. They are usually asymptomatic incidental findings and localized in the midline. However, they may occasionally produce neurological symptoms such as seizure, headache, mental changes, paresis. Currently, diagnosis of intracranial lipomas is made on based of imaging modalities, particularly Magnetic resonance imaging(MRI). Because Lipomas are strongly adherent to the surroundings and typically enclose both vessels and nerves, Surgical approach is rarely indicated.

• Asian Journal of Innovation and Policy
• /
• 제9권2호
• /
• pp.106-132
• /
• 2020

This study intends to add a factor to the discussion on the sectoral systems of innovation through Korea's response to the COVID-19 pandemic. The Korean approach is summarized as follows: the first response centers on technology and innovation. These include the development of diagnostic test methods and accurate test kits, first in the world, the use of ICT technology in epidemiological investigations, the technical response in the field, and the competitive edge in the development of medicine and vaccines that were behind the developed countries. The second response is an aggressive effort implemented just after the Chinese announcement, before the domestic outbreak; the third response is the open policy that induces voluntary participation of all subjects and people by opening all information. More important is the leadership at the national level shown in the past Korean experience and most advanced countries. National leadership must be the missing factor.

• 대한음성언어의학회:학술대회논문집
• /
• 대한음성언어의학회 1995년도 제4회 학술대회 심포지움 및 워크샵
• /
• pp.128-136
• /
• 1995

Diagnostic evaluation for voice disorders requires a multidimensional approach : physiological examination of the larynx and the vocal tract, aerodynamic studies, examinations of vocal fold vibrations, psychoacoustic evaluations, acoustical analyses, and so on. Previous studies with the use of a computer system suggested that the acoustic evaluation is quite promising for differentiating some causative diseases of voice disorders(Hiki et al., 1975a, b, 1976 ; Kakita et al., 1980). However, a well-equipped computer system for acoustic analysis is very expensive and not available in most voice clinics. A sound spectrograph is available in many voice clinics. (omitted)

• Imaging Science in Dentistry
• /
• 제41권4호
• /
• pp.161-165
• /
• 2011

It is difficult to take intraoral radiographs in some patients who are intolerable to place the film in their mouth. For these patients, Newman and Friedman recommended a new technique of extraoral film placement. Here we report various cases that diagnostic imaging was performed in patients using the extraoral periapical technique. This technique was used to obtain the radiographs for the patients with severe gag reflex, pediatric dental patients, and patients with restricted mouth opening. This technique can be recommended as an alternative to conventional intraoral periapical technique in cases where intraoral film placement is difficult to achieve.