• Title/Summary/Keyword: diagnosis of degradation

검색결과 237건 처리시간 0.022초

Next Generation Sequencing (NGS), A Key Tool to open the Personalized Medicine Era

  • Kwon, Sun-Il
    • 대한임상검사과학회지
    • /
    • 제44권4호
    • /
    • pp.167-177
    • /
    • 2012
  • Next-Generation Sequencing (NGS) is a term that means post-Sanger sequencing methods with high-throughput sequencing technologies. NGS parallelizes the sequencing process, producing thousands or millions of sequences at once. The latest NGS technologies use even single DNA molecule as a template and measures the DNA sequence directly via measuring electronic signals from the extension or degradation of DNA. NGS is making big impacts on biomedical research, molecular diagnosis and personalized medicine. The hospitals are rapidly adopting the use of NGS to help to patients understand treatment with sequencing data. As NGS equipments are getting smaller and affordable, many hospitals are in the process of setting up NGS platforms. In this review, the progress of NGS technology development and action mechanisms of representative NGS equipments of each generation were discussed. The key technological advances in the commercialized platforms were presented. As NGS platforms are a great concern in the healthcare area, the latest trend in the use of NGS and the prospect of NGS in the future in diagnosis and personalized medicine were also discussed.

  • PDF

A Vehicle SoC Fault Diagnosis Technique using FlexRay Protocol

  • Kang, Seung-Yeop;Jung, Ji-Hun;Park, Sung-Ju
    • 한국컴퓨터정보학회논문지
    • /
    • 제21권1호
    • /
    • pp.39-47
    • /
    • 2016
  • In this paper, we propose vehicle SoC fault diagnosis platform using FlexRay protocol in order to detect the faults of semiconductor control chip even after vehicle production. Before FlexRay protocol by sending NFI (Null Frame Indicator) bit among the header segment and a specific identifier in the payload segment of FlexRay frame, this technique can be distinguishable from normal mode and test mode. By using this technique, it is possible to detect the faults such as performance degradation of vehicle network system caused by the aging or several problems of vehicle semiconductor chip. Also high reliability and safety of vehicle can be maintained by using structural test for vehicle SoC fault detection.

신생아 혈액 응고질환: 출혈 경향을 보이는 신생아에 대한 진단적 접근 (Neonatal Coagulation Disorder: Diagnostic Approaches for Bleeding Neonates)

  • 김천수
    • Neonatal Medicine
    • /
    • 제18권1호
    • /
    • pp.6-13
    • /
    • 2011
  • All newborn infants with clinically significant bleeding should be evaluated for a hemostatic deficit. Medical history should include the following data: familial bleeding disorders, maternal illness and medication, age of bleeding onset, and prophylactic administration of vitamin K. The first essential step for evaluating bleeding neonates is determining whether the baby is sick or well. The physician should also evaluate the extent of the bleeding, features of bleeding lesions, and other abnormal findings from the physical examination. Skeletal anomalies may provide diagnostic clues. Depending on the clinical features and results of screening tests, other tests including coagulation factors may be useful for determining the diagnosis. All laboratory results must be considered in the context of age-related reference values. The platelet function analyzer provides a promising alternative to bleeding time. Fibrin degradation products and D-dimers are used for screening and specially testing fibrinolytic activity, respectively. The Apt test may help to rule out factors derived from maternal blood. Radiologic imaging studies are important because asymptomatic intracranial hemorrhages are common in neonates.

열상카메라를 이용한 애자의 열화에 관한 연구 (A Study on the Degradation of Insulators using Thermal Image Camera)

  • 김정태;김지홍;구자윤;윤지호;함길호
    • 대한전기학회:학술대회논문집
    • /
    • 대한전기학회 2000년도 하계학술대회 논문집 C
    • /
    • pp.1933-1935
    • /
    • 2000
  • In this paper, it was tried to find out the minimum measurement range in the diagnosis of insulators using thermal image camera, for the purpose, leakage currents and thermal images were observed simultaneously for the insulators of which surface had been artificially polluted by salt fog. As a result. the surface temperature was increased with leakage currents. Also, the results of AC breakdown tests for the insulator of which temperature rise was more than 1 $^{\circ}C$ showed to be bad. Therefore, through the study on the relationship between leakage current, temperature rise and AC breakdown voltages, the diagnosis of the insulator in site would be possible using the thermal image camera.

  • PDF

전자파를 이용한 전동기 절연열화 진단시스템의 설계(2) (Design of Diagnosis System for Insulation Degradation of Motor by using Electromagnetic Wave(2))

  • 유권종;김이곤
    • 한국정보통신학회:학술대회논문집
    • /
    • 한국해양정보통신학회 2000년도 추계종합학술대회
    • /
    • pp.677-682
    • /
    • 2000
  • 본 연구는 전동기의 부분방전에 의해 발생되는 전자파를 측정하여 전동기의 열화상태를 진단할 수 있는 진동기 절연열화 진단시스템을 설계하였다. 청장 전동기에서 부분방전에 의한 전자파를 on-line으로 측정하고, 측정된 데이터로부터 정량화된 특징 데이터를 추출한 후 전자파의 평균 에너지 분포를 이용하여 전동기의 절연열화 상태를 판단하는 방법을 제시하였으며, 현장에서 사용 중인 Megger시험과 비교하였다.

  • PDF

Diagnosis and Evaluation of Conservation State of Mural Paintings in Payathonzu Temple on Bagan Heritage Site in Myanmar

  • Lee, Hwa Soo;Kim, Seol Hui;Han, Kyeong Soon
    • 보존과학회지
    • /
    • 제35권5호
    • /
    • pp.494-507
    • /
    • 2019
  • A diagnostic investigation of the conservation state of damaged murals of the Payathonzu temple mainly indicated delamination, exfoliation, and contamination of the coloring layer; cracks and damage to the wall; and separation from gaps. In particular, vulnerabilities resulting from cracks in the wall and damage from gaps demand swift reinforcement measures. Ultrasonic testing uncovered damage caused by gaps between the base layer and plastered wall in several areas of the mural, vulnerable parts in the wall around the cracks, and considerable degradation of the physical properties where cracks and gaps were severe. Moisture measurements identified vast disparities in moisture depending on location even within a single area of the mural, and it was clear that these disparities were the result of environmental conditions such as humidity. Damage to the murals in monument 477 was the most severe, and a diagnostic of the physical properties uncovered severe physical damage to the upper part of the mural as well as to the corridor ceiling, thus presenting the need for conservation treatment utilizing scientific diagnosis as well as objective data.

가스분해 분석기법을 활용한 가스 전열 변압기의 상태 진단 연구 (A Study on the Condition Diagnosis for A Gas-insulated Transformer using Decomposition Gas Analysis)

  • 김아름;곽병섭;전태현;박현주
    • KEPCO Journal on Electric Power and Energy
    • /
    • 제8권2호
    • /
    • pp.119-126
    • /
    • 2022
  • A growing number of gas-insulated transformers in underground power substations in urban areas are approaching 20 years of operation, the time when failures begin to occur. It is thus essential to prevent failure through accurate condition diagnosis of the given facility. Various solid insulation materials exist inside of the transformers, and the generated decomposition gas may differ for each gas-insulated equipment. In this study, a simulation system was designed to analyze the deterioration characteristics of SF6 decomposition gas and insulation materials under the conditions of partial discharge and thermal fault for diagnosis of gas-insulated transformers. Degradation characteristics of the insulation materials was determined using an automatic viscometer and FT-IR. The analysis results showed that the pattern of decomposition gas generation under partial discharge and thermal fault was different. In particular, acetaldehyde was detected under a thermal fault in all types of insulation, but not under partial discharge or an arc condition. In addition, in the case of insulation materials, deterioration of the insulation itself rapidly progressed as the experimental temperature increased. It was confirmed that it was possible to diagnose the internal discharge or thermal fault occurrence of the transformer through the ratio and type of decomposition gas generated in the gas-insulated transformer.

고자장 수·변전 설비에서의 적외선 카메라용 반사경 설계 (Design of a Reflector Mirror for Infrared Camera in the High Magnetic Field of Power System)

  • 배영철
    • 한국전자통신학회논문지
    • /
    • 제9권2호
    • /
    • pp.255-260
    • /
    • 2014
  • 최근에 열화상 카메라는 수 변전 설비의 열화 상태를 진단하는데 많이 사용하고 있다. 그러나 자장이 높은 곳에서는 열화상 카메라의 전자부가 높은 자장으로 인하여 제대로 동작하지 못하는 문제점이 발생한다. 이를 해결하기 위해 일반적으로 반사경을 사용할 수 있으나 반사경의 휨 등에 의해 반사 성능이 떨어지는 문제점이 있다. 본 논문에서는 이러한 문제점을 극복하기 위하여 아크릴 판에 알루미늄을 코팅하여 설계한 후 이를 제작하여 측정의 오차를 줄이고 측정 효율을 높이는 방법을 제시한다.

전기기기 절연열화진단 시스템개발에 관한 고찰 (Study on Development of Insulation Degradation Diagnosis System for Electrical System)

  • 김이곤;유권종;김서영;조용섭;박봉서;최시영;심상욱
    • 대한전기학회:학술대회논문집
    • /
    • 대한전기학회 2001년도 합동 추계학술대회 논문집 정보 및 제어부문
    • /
    • pp.231-235
    • /
    • 2001
  • Insulation aging diagnosis system provides early warning regarding electrical equipment defect. Early warning is very important in that it can avoid great losses resulting from unexpected shutdown of the production line. Since relations of insulation aging and partial discharge dynamics are non-linear, it is very difficult to provide early warning in an electrical equipment. In this paper, we propose the design method of insulation aging diagnosis system that use a magnetic wave and acoustic signal to diagnoses an electrical equipment. Proposed system measures the partial discharge on-line from DAS(Data Acquisition System) and acquires 2D Patterns from analyzing it. For fettering the noise contained in sensor signals we used ICA algorithms. Using this data design of the neuro-fuzzy model that diagnoses an electrical equipment is investigated. Validity of the new method is asserted by numerical simulation.

  • PDF

GIS 진단시스템의 평가를 위한 PD 모의 펄스발생기 개발에 관한 연구 (A Study on the Development of PD Simulation Pulse Generator for Evaluation of GIS Diagnosis System)

  • 김성주;장석훈;조국희
    • 한국안전학회지
    • /
    • 제33권2호
    • /
    • pp.21-27
    • /
    • 2018
  • The expansion and stable operation of electric power facilities are important factors with development of industrial facilities in modern society. In high-voltage equipment such as GIS, the insulation characteristics may be deterioated by environment-friendly gas adaption and miniaturization. There is also the possibility of accidents due to insulation breakdown due to the deterioration of power facilities. Therefore, it is necessary to extend the diagnosis system to continuously monitor the danger signals of these power equipment and to prevent accidents. Most of the internal defects in the GIS system are conductive particles, floating electrode defects, protrusion defects, and the like. In this case, a partial discharge phenomenon is accompanied. These partial discharge signals occur irregularly and various noise signals are included in the field, so it is difficult to evaluate the reliability in the development of the diagnostic system. In this paper, a study was made on equipment capable of generating a partial discharge simulated signal that can be adjusted in size and frequency to be applied to a diagnostic device by electromagnetic wave detection method. The PD simulated pulse generator consists of a user interface module, a high-voltage charging module, a pulse forming circuit, a voltage sensor and an embedded controller. In order to simulate the partial discharge phenomenon similar to the actual GIS, a discharge cell was designed and fabricated. The application of the prototype pulse generator to the commercialized PD diagnosis module confirmed that it can be used to evaluate the performance of the diagnostic device. It can be used for the development of GIS diagnosis system and performance verification for reliability evaluation.