• Clinical and Experimental Pediatrics
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• v.48 no.8
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• pp.826-831
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• 2005

Purpose : This study is directed to evaluate standardized developmental test performances of infants and children who, as fetuses, had mild isolated cerebral ventriculomegaly diagnosed by ultrasound. Methods : All prenatal sonographic findings from 2001 to 2002 were evaluated. Live isolated mild ventriculomegaly(IMVM) of 10-15 mm were observed in 95 cases(1.1 percent). Standardized developmental testing of 40 cases of IMVM and 36 cases in a comparison group were offered to parents Both groups of children were adjusted to normal antepatum subjects with respect to sex, race, indication for ultrasound and gestational age at the time of ultrasound. Test of cognitive and motor development(Bayley Scales of Infant Development, Second Edition; BSID-II) were administered by developmental examiners. Results : Forty cases and 34 comparison sujects completed the testing. The IMVM and comparison groups were similar with respect to parental age, gestational age, birth weight, familial socioeconomic status. The IMVM subjects scored lower than the comparison group on both the BSID-II, but there was not statistically significant. differences; metal development index(MDI)($92.7{\pm}12.9$ vs $94.7{\pm}14.1$, P=0.47) and psychomotor development index(PDI)($100.3{\pm}14.1$ vs $101.3{\pm}10.7$, P=0.75). Eleven cases(27.5 percent) of IMVM group and five cases(14.7 percent) of the comparison group were developmentally delayed, but most cases in both groups showed mild delays. Resolution or lack of progression, lateral ventricle diameter ${\leq}12mm$ and females were associated with better scores, but there were not statistically significant. Polarity, and head circumference were not related to later development. Conclusion : This study show children with MIVM did not delay performance in the developmental test, but we might suggest a tendency to increase the risk of mild developmental delay.

• Journal of Korea Entertainment Industry Association
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• v.15 no.7
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• pp.181-192
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• 2021

This study was conducted to investigate the effects of a participatory rehabilitation program on sit-rise and rise-to-walk test performances, and perception and motor skills in adults with medically vulnerable individuals and, adults with developmental disabilities in particular. Seventeen adults with developmental disabilities participated in a participatory rehabilitation program using resistance bands and exercise balls, for 60 minutes once weekly over 13 weeks. Their performances were measured before and immediately after the intervention, and 12 weeks after. The findings were as follows. In the sit-rise test, the number of times rising from sitting posture increased after the intervention versus before, but the difference was not statistically significant. In the rise-to-walk test, the performance showed statistically significant difference over time, and the post-hoc test showed a significant effect after the intervention versus before. There was no significant difference in perception and motor skills. In sum, the participatory rehabilitation program positively influenced dynamic balancing related to functional activities but had no significant effect on perception and motor skills, which is related to motor control and motor learning. It is suggested that to increase the participation in community activities, reduce fall risk, and improve dynamic balancing abilities in adults with developmental disabilities, participatory rehabilitation programs should be utilized to promote the physical wellbeing.

• The Journal of Korean Physical Therapy
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• v.15 no.3
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• pp.251-264
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• 2003

Alcohol exposure during development leads to significant long-term neurobehavior dysfunction and central nervous system alteration. The purpose of this study was to determine the effects of enriched enviroment in developmental period through motor behavior test and expression of BDNF. Neonatal rat exposed to alcohol on postnatal days 4 through 10 were studied. Female Sprague-Dawley pups were assigned to two groups. Experimental group(EG) via 4.5 g kg-1day-1 of ethanol was housed in enriched enviornment for 9 weeks. The main result of this study were as follows: 1. There was significant difference in the mean of weight change between control and experimental group. 2. In motor behavior test, there was significant difference in the mean of weight change between control and experimental group. 3. Regarding the immunoreactivity of BDNF were higher appeared experimental group than control group. In conclusion, the present results reveals that enriched enviroment in developmental period is to be extremely useful in neuronal reprganization and motor behavior improvement after alcohol exposure.

• Journal of the Korea Furniture Society
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• v.21 no.3
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• pp.261-272
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• 2010

The aim of the present study was to investigate the relations between wooden toy and development of infant and young children by taking only the commercialized wooden furniture which would be suitable for the developmental area for infant and young children, among the physical environment influencing the balanced development and development for them. The recommended standard for them was the commercialized good and the only advanced toys for the development of infant and young children was primary selected, in case of different furniture for same purpose with regardless of manufacturer, country of origin and price. The selected wooden toys for development of infant and young children covered the following test conditions. They keep the soft and clean surfaces and the corners are the round-finished so safe. The dyeing and coloring are so clear like the rainbow-colored in compliance with the international safety norm, and the paint material used are harmless to the people, because they have already passed the European Safety Norm EN 71 which is the most authoritative and strict standard in the world and contained accordingly little heavy metals, toxic substances and also allergy pigment under the maximum permissible standard. The size of wooden toys are not small enough for infant and young children to be able to swallow and this is important check point, because infants tend to feel the object in their own touching and therefore to have everything to the lip. The paint used was the toys-oriented goods and proved by the test regarding saliva and sweat.

• Journal of Korean Academy of Fundamentals of Nursing
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• v.20 no.1
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• pp.37-45
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• 2013

Purpose: The purpose of this study was to identify suicidal ideation in high school students in urban and rural areas. Methods: For this research two urban and two rural high schools in four cities were chosen. The participants were 713 students (373 in the urban area, 340 in the rural area). The survey was conducted from June 1 to July 31, 2012. Data were analyzed with chi-square test, t-test, ANOVA, and multiple regression using SPSS 18.0. Results: Results showed that 19.5% of respondents had suicidal ideation within the past 1 year. There were significant differences in suicidal ideation and developmental assets between the two areas. Multiple regression analysis revealed that support, school violence, gender, family abuse, constructive use of time, and positive identity were significant predictors and explained 26% of suicidal ideation for high school students in urban areas. On the other hand, in rural areas, family abuse, gender, positive identity, smoking and empowerment were significant predictors and explained 31% of suicidal ideation. Conclusion: The findings indicate that implementation of a suicide prevention program in which consideration is given to these factors, and taking into account differences between urban and rural students would be helpful in reducing suicidal ideation.

• Journal of Genetic Medicine
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• v.18 no.1
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• pp.31-37
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• 2021

Purpose: To summarize the results of chromosomal microarray analysis (CMA) for copy number variants (CNVs) detection and clinical utility in a single tertiary hospital. Materials and Methods: We performed CMA in 46 patients over the course of two years. Detected CNVs were classified into five categories according to the American College of Medical Genetics and Genomics guidelines and correlated with clinical manifestations. Results: A total of 31 CNVs were detected in 19 patients, with a median CNV number per patient of two CNVs. Among these, 16 CNVs were classified as pathogenic (n=3) or likely pathogenic (LP) (n=11) or variant of uncertain significance (n=4). The 16p11.2 deletion and 16p13.11 deletion classified as LP were most often detected in 6.5% (3/46), retrospectively. CMA diagnostic yield was 24.3% (9/37 patients) for symptomatic patients. The CNVs results of the commercial newborn screening test using next generation sequencing platforms showed high concordance with CMA results. Conclusion: CMA seems useful as a first-tier test for developmental delay with or without congenital anomalies. However, the classification and interpretation of CMA still remained a challenge. Further research is needed for evidence-based interpretation.

• Food Science and Industry
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• v.54 no.2
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• pp.82-92
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• 2021

To resolve difficulties of export process and strengthen competitiveness, Korea National Food Safety Certificate (K-NFSC), a comprehensive food safety support system, has been promoted to introduction. K-NFSC is at a developmental stage where the government certifies the safety of exported K-foods by developing Korean certification system based on HACCP and food safety management added for international use, and provides consulting on regulations of customs clearance and safety test analysis of food intended for export. To apply for the Global Food Safety Initiative (GFSI) technical equivalence in 2022, developmental direction of Korean certification system is set referring to FSSC22000. If selected as participants of an export supporting project, regulatory information such as customs clearance procedures and food labeling will be provided. In addition, the results of safety test analysis will be certified to help export products pass customs entry. K-NFSC is expected to support K-food exports and be growth engine for K-food industry.

• Journal of the Korean Society of Clothing and Textiles
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• v.19 no.5
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• pp.790-800
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• 1995

This study was done to provide basic data for better fittness of infants and children's clothes and to get the developmental aspect of the subjects. The subjects were total 610 infants and children, 302 boys and 308 girls between month 12 to 59. 67 dependent variables were analyzed by the method of Duncan Test as Multiple Range Test among 8 groups anti T-test between male and female of same age groups. Following results were obtained: 1. In Duncan Test of the direct measurement items, the most subjects between group 1 and 8 were significantly different in the majority of dependent varibles, especially in height and length items 2. In Duncan Test of the body indices, as the subjects 'ages are higher, their bodies were balanced with the growth of the girth of their lower body. 3. In T-test, the significant difference between male and female of same month group was appeared mainly from 4th group to 7th group.

• Journal of the military operations research society of Korea
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• v.31 no.1
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• pp.93-106
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• 2005

The complexity of modern weapon systems using the IT(intelligence technology) demands that rapid and effective transition from force requirements to deployment and fielding. Thus this paper deals with the DT&E(developmental test & evaluation), OT&E(operational test & evaluation) and SBT(simulation based test) procedure using the case study in the test & evaluation of weapon systems. This study is aimed to produce the effective test & evaluation method of weapon systems in the change of acquisition environment.

• Environmental Mutagens and Carcinogens
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• v.16 no.1
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• pp.30-34
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• 1996

This study was performed to examine the availability of using medaka (Oryzias latipes) in teratological test. Medaka embryos were collected within 2 hours post-fertilization and cultured in petri dishes containing buffered saline until hatching. The embryos were treated with 0.56 mg/l chlorpyrifos-methyl and 10 mM methyl methanesulfonate at 20 stages (about 35 hours post-fertilization). Eleven developmental features were selected and observed from 33 stages (about 9 days post-fertilization). Scoring system was developed and applicated for the measurement of potential teratological effects by the test compound. Chlorpyrifos-methyl did not induce teratological effect in medaka embryos. However, we found teratological test using medaka embryo reduced the cost, labors, period and space of experiment significantly compared with teratological study using rodents. Above findings strongly suggest that medaka embryo can be used as a lab animal model for teratogenicity test instead of rodents.