• Proceedings of the Korean Society of Surveying, Geodesy, Photogrammetry, and Cartography Conference
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• 2009.04a
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• pp.55-57
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• 2009

This research was supported by agrant (07KLSGC02) from Cutting-edge Urban Development - Korean Land Spatialization Research Project funded by Ministry of Land, Transport and Maritime Affairs.

• Archives of Pharmacal Research
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• v.10 no.4
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• pp.245-249
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• 1987

Cardiovascular disease is at present the leading cause of deth in the United States and other in dustrilized countries. A major contributing factor of cardiovascular disease is essential hypertension. Untreated, essential hypertension is considered a risk factor for sudden death due to myocardial infarctions, as well as a risk factor for cerebral vascular disease, renal failure and congestive heart failure. During the last decade, significant progress has been made in the basic knowledge of the pathogenesis of hypertension as well as in the development of new antihypertensive drugs.

• Molecules and Cells
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• v.45 no.11
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• pp.789-791
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• 2022

Targeting fibroblast growth factor receptors (FGFRs) has been slow compared to other targeted cancer therapies for receptor tyrosine kinases, such as epidermal growth factor receptors. The low efficacy and variable response have limited the growth of FGFR inhibitors in clinical use. Nevertheless, recent systematic and genomic approaches have identified the biological conditions for effectively targeting FGFRs and can accelerate the development of targeted drugs. Under clinical and preclinical trials, the inhibitors started fast growing furious races to target FGFRs. Finally, FGFRs will be more actionable and targetable with more precise and effective drugs at the end of the race, passing the finish line.

• Korean Journal of Breeding Science
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• v.43 no.5
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• pp.457-463
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• 2011

Plant specific gene family, NAC (NAM, ATAF, and CUC) transcription factors have been characterized for their roles in plant growth, development, and stress tolerance. In this study, we isolated OsNAC69 gene and analyzed expression level by inoculation of bacterial leaf blight pathogen, Xanthomonas oryzae pv. oryzae (Xoo). NAC transcription factor family can be divided into five groups (I-V). On the basis of phylogenetic analysis, OsNAC69 was fall into group II. OsNAC69 was strongly induced 1 hr after infected with Xoo. To investigate its biological function in the rice, we constructed vector for overexpression in rice, and then generated transgenic rice lines. Gene expression of OsNAC69-overexpressed transgenic rice lines were analyzed by northern blot. Analysis of disease resistance to pathogen Xoo, nine OsNAC69-overexpressed transgenic rice lines showing high expression level of OsNAC69 were shown more resistant than wild type. These results suggest that OsNAC69 gene may play regulatory role during pathogen infection.

• Journal of the Korean Dietetic Association
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• v.14 no.2
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• pp.186-197
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• 2008

The aim of this study was to measure the brand images of contract foodservice management companies by identifying brand image attributes and then developing a measurement scale to measure the weight of these attributes. The measurement scale was developed by following a 5-stage process that included face-to-face interviews with experts, literature review, questionnaire surveys, verification of scale validity, exploratory factor analysis, and confirmatory factor analysis. A total of 137 items measuring brand image were collected: 37 items from studies of brand image and corporate image, 55 items from studies of contract foodservice management companies and 45 items from the internet and websites of contract foodservice management companies. A survey was then conducted to assess the validity and reliability of the questionnaire items. Ultimately, the 137 items were reduced to 40 items. The calculated Cronbach's alpha for the 40 brand image items was 0.934, demonstrating good internal consistency. Based on exploratory factor analysis (EFA), employee attitude, menu content, corporate image, dining location and ambience, along with 33 subattributes, were identified as brand image attributes. Employee attitude was the most significant attribute influencing brand image. After confirmatory factor analysis (CFA) and a review process, four brand image attributes and 33 subattributes were finalized and incorporated into the scale.

• Journal of the Society of Naval Architects of Korea
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• v.44 no.1 s.151
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• pp.26-31
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• 2007

Understanding viscoelastic properties of composite materials is essential for the design and analysis of composite structures. Specially, the loss factor and Young's modulus must be known to develop finite element codes for a composite structure with several damping materials. In this study, an advanced technique for obtaining accurate loss factor and Young's modulus of a composite structure is introduced based on the method of American Society for Testing and Materials (ASTM). The loss factor and Young's modulus of a composite structure are measured for different temperatures by performing the test in a vibration measurement room where temperature can be controllable from 5 to 45 Celsius.

• International Journal of Contents
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• v.14 no.3
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• pp.53-60
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• 2018

Based on the previous studies on sinkholes and ground subsidence conducted until date, the factors affecting the occurrence of sinkholes can be divided into natural environmental factors and human environmental factors in accordance with the purpose of the study. Furthermore, to be more specific, the human environment can be classified into the artificial type and the social type. In this study, the assessment indices for assessing risks of sinkholes and ground subsidence were developed by performing AHP analysis based on the results of the study by Lee et al. (2016), who selected the risk factors for the occurrence of sinkholes by performing Delphi analysis targeting relevant experts. Analysis showed that the artificial environmental factors were of significance in affecting the occurrence of sinkholes. Explicitly, the underground factors were found to be of importance in the natural environment, and among them, the level of underground water turned out to be an imperative influencing factor. In the artificial environment, the underground and subterranean structures exhibited similar importance, and in the underground structures, the excessive use of the underground space was found to be an important influencing factor. In the subterranean ones, the level of water leakage and the erosion of the water supply and sewage piping system were the influential factors, and in the surface, compaction failure was observed as an imperative factor. In the social environment, the regional development, and above all, the groundwater overuse were found to be important factors. In the managemental and institutional environment, the improper construction management proved to be the most important influencing factor.

• Korean Journal of Air-Conditioning and Refrigeration Engineering
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• v.22 no.3
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• pp.149-155
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• 2010

In the present study, the characteristics on the internal flow and heat transfer of the dimple-type plate heat exchanger were numerically investigated. For the numerical analysis, the conjugate heat transfer analysis between hot fluid-separating plate-cold fluid was performed using the periodic boundary condition at the center area of the plate and appropriate inlet and outlet conditions for the two streams. The numerical results were validated by the comparison with the experimental data. From these results, the correlations of the Colburn j-factor for the heat transfer and the Fanning f-factor for the flow friction were obtained. The present results could be applicable for the optimal design of dimple-type plate heat exchanger.

• Geomechanics and Engineering
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• v.6 no.1
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• pp.17-31
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• 2014

This paper investigates the development of failure surfaces induced by an embankment on soft marine clay deposits and the characteristics of such surfaces through numerical simulations and its comparative study with monitoring results. It is well known that the factor of safety of embankment slopes is closely related to the vertical loading, including the height of the embankment. That is, an increase in the embankment height reduces the factor of safety. However, few studies have examined the relationship between the lateral movement of soft soil beneath the embankment and the factor of safety. In addition, no study has investigated the distribution of the pore pressure coefficient B value along the failure surface. This paper conducts a continuum analysis using finite difference methods to characterize the development of failure surfaces during embankment construction on soft marine clay deposits. The results of the continuum analysis for failure surfaces, stress, displacement, and the factor of safety can be used for the management of embankment construction. In failure mechanism, it has been validated that a large shear displacement causes change of stress and pore pressure along the failure surface. In addition, the pore pressure coefficient B value decreases along the failure surface as the embankment height increases. This means that the rate of change in stress is higher than that in pore pressure.

• Journal of Agricultural Extension & Community Development
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• v.14 no.2
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• pp.417-436
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• 2007

The purpose of this study was to prepare for developing rural house remodeling techniques utilizing the traditional residence factor. The study was carried out through both literature research and on-site research. The traditional residence space factors were identified through literature research and on-site research was carried out through analysis of the rural house remodeling cases. The results of this study was as follows ; 1) Traditional space factors were derived by literature research i. e. space arrangement (topography, direction, plane arrangement), exterior factors; walls, madang, interior factors; roofs, ondol, floors, colours. 2) The traditional residence factor utilizations of remodeling were applied a result through investigation case and analysis. Five rural houses in Namsa village, Danseong-myeon, Sangcheong-gun, Gyeongsangnam-Do were analyzed as remodeling cases including traditional residence factors. There were limitation of budget problems and material selection in the traditional residence factor utilizations of remodeling. The researchers have chosen target rural houses which applied for traditional residence factors to remodel the rural houses, and the most important factor to consider was harmony with rural unique characteristics. The researchers suggested considerations should be placed on development with energy savings and convenience in rural house remodelling.